Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ihara Chemical Industry Co Ltd
Kumiai Chemical Industry Co Ltd
Original Assignee
Ihara Chemical Industry Co Ltd
Kumiai Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ihara Chemical Industry Co Ltd, Kumiai Chemical Industry Co LtdfiledCriticalIhara Chemical Industry Co Ltd
Priority claimed from EP88114855Aexternal-prioritypatent/EP0306996B1/en
Publication of DE3382642D1publicationCriticalpatent/DE3382642D1/en
Application grantedgrantedCritical
Publication of DE3382642T2publicationCriticalpatent/DE3382642T2/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
Prepn. of 3,5-dioxocyclohexanecarboxylic acid derivs. of formula (I) or salt, where R = H, alkyl, alkylthioalkyl or opt. substd. phenyl; and R' = alkyl, opt. substd. benzyl, phenethyl, phenoxy-, 2-thienyl-, alkoxy- or alkylthiomethyl; comprises: (i) cyclising a cpd. of formula (II) in presence of base to give (III), where M' = alkali metal; (ii) opt. treating (III) with acid to give (IV); (iii) reacting (III) or (IV) with R'-CO-Cl (V) to give (VI); and (v) rearranging (VI) in presence of a catalyst to give (I) and opt. converting to a salt by reacting with inorganic or organic cation.
DE8888114855T1983-09-231983-09-23
METHOD OF PRODUCING DERIVATIVES OF 3,5-DIOXOCYCLOHEXANCARBONIC ACID.
Expired - LifetimeDE3382642T2
(en)