DE3375918D1 - Substituted tropyl and pseudotropyl benzoates and their use in migraine treatment - Google Patents

Substituted tropyl and pseudotropyl benzoates and their use in migraine treatment

Info

Publication number
DE3375918D1
DE3375918D1 DE8383440062T DE3375918T DE3375918D1 DE 3375918 D1 DE3375918 D1 DE 3375918D1 DE 8383440062 T DE8383440062 T DE 8383440062T DE 3375918 T DE3375918 T DE 3375918T DE 3375918 D1 DE3375918 D1 DE 3375918D1
Authority
DE
Germany
Prior art keywords
tropyl
substituted
pseudotropyl
migraine treatment
benzoates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383440062T
Other languages
English (en)
Inventor
John R Fozard
Maurice W Gittos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Merrell Dow France et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow France et Cie filed Critical Merrell Dow France et Cie
Application granted granted Critical
Publication of DE3375918D1 publication Critical patent/DE3375918D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8383440062T 1982-12-10 1983-12-06 Substituted tropyl and pseudotropyl benzoates and their use in migraine treatment Expired DE3375918D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08235296A GB2132189B (en) 1982-12-10 1982-12-10 Tropyl and pseudotropyl benzoates and their use in migraine treatment

Publications (1)

Publication Number Publication Date
DE3375918D1 true DE3375918D1 (en) 1988-04-14

Family

ID=10534881

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383440062T Expired DE3375918D1 (en) 1982-12-10 1983-12-06 Substituted tropyl and pseudotropyl benzoates and their use in migraine treatment

Country Status (17)

Country Link
EP (1) EP0112266B1 (de)
JP (1) JPS59152383A (de)
KR (1) KR840006999A (de)
AT (1) ATE32896T1 (de)
AU (1) AU558082B2 (de)
CA (1) CA1202027A (de)
DE (1) DE3375918D1 (de)
DK (1) DK568483A (de)
ES (1) ES8505636A1 (de)
GB (1) GB2132189B (de)
GR (1) GR79159B (de)
IE (1) IE56327B1 (de)
IL (1) IL70384A0 (de)
NO (1) NO834540L (de)
NZ (1) NZ206496A (de)
PH (1) PH20063A (de)
ZA (1) ZA839044B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204356A (en) * 1985-07-24 1993-04-20 Glaxo Group Limited Treatment of anxiety
US4906755A (en) * 1986-11-03 1990-03-06 Merrell Dow Pharmaceuticals Inc. Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds
AUPR701101A0 (en) * 2001-08-14 2001-09-06 Commonwealth Scientific And Industrial Research Organisation Agonists and antagonists of 5ht3-like receptors of invertebrates as pesticides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1161325A (fr) * 1954-01-22 1958-08-26 Sandoz Ag Procédé de préparation d'esters de 6-alcoxy-tropines présentant un atome d'azotequaternaire

Also Published As

Publication number Publication date
AU2215283A (en) 1984-06-14
IL70384A0 (en) 1984-03-30
GR79159B (de) 1984-10-02
EP0112266A3 (en) 1985-10-23
KR840006999A (ko) 1984-12-04
EP0112266B1 (de) 1988-03-09
DK568483A (da) 1984-06-11
AU558082B2 (en) 1987-01-15
ES527842A0 (es) 1985-06-16
ES8505636A1 (es) 1985-06-16
IE56327B1 (en) 1991-06-19
IE832885L (en) 1984-06-10
NO834540L (no) 1984-06-12
ATE32896T1 (de) 1988-03-15
NZ206496A (en) 1986-07-11
GB2132189A (en) 1984-07-04
ZA839044B (en) 1984-07-25
CA1202027A (en) 1986-03-18
DK568483D0 (da) 1983-12-09
GB2132189B (en) 1986-02-05
PH20063A (en) 1986-09-18
JPS59152383A (ja) 1984-08-31
EP0112266A2 (de) 1984-06-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee