DE3374199D1 - Isoxazole (5,4-b) pyridines - Google Patents
Isoxazole (5,4-b) pyridinesInfo
- Publication number
- DE3374199D1 DE3374199D1 DE8383102648T DE3374199T DE3374199D1 DE 3374199 D1 DE3374199 D1 DE 3374199D1 DE 8383102648 T DE8383102648 T DE 8383102648T DE 3374199 T DE3374199 T DE 3374199T DE 3374199 D1 DE3374199 D1 DE 3374199D1
- Authority
- DE
- Germany
- Prior art keywords
- pyridines
- isoxazole
- depressant
- antiinflammatory
- cns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 title abstract 2
- RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000005792 cardiovascular activity Effects 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8209361 | 1982-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3374199D1 true DE3374199D1 (de) | 1987-12-03 |
Family
ID=10529406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383102648T Expired DE3374199D1 (de) | 1982-03-30 | 1983-03-17 | Isoxazole (5,4-b) pyridines |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4530927A (de) |
| EP (1) | EP0090275B1 (de) |
| JP (1) | JPS58177992A (de) |
| AT (1) | ATE30425T1 (de) |
| AU (1) | AU561013B2 (de) |
| CA (1) | CA1204440A (de) |
| DE (1) | DE3374199D1 (de) |
| DK (1) | DK143583A (de) |
| ES (1) | ES8405407A1 (de) |
| GR (1) | GR77945B (de) |
| IL (1) | IL68171A (de) |
| PH (1) | PH18337A (de) |
| ZA (1) | ZA831738B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2161667B (en) * | 1984-07-12 | 1988-04-27 | John Spencer Liggett | Portable facial image synthesiser |
| JPH04368375A (ja) * | 1991-06-17 | 1992-12-21 | Otsuka Pharmaceut Factory Inc | イソオキサゾール誘導体 |
| EP0835255A1 (de) * | 1995-06-29 | 1998-04-15 | Novo Nordisk A/S | Neue substituierte azazyklische verbindungen |
| JPWO2002102807A1 (ja) * | 2001-06-14 | 2004-09-30 | 萬有製薬株式会社 | 新規イソキサゾロピリドン誘導体及びその用途 |
| GB0124848D0 (en) * | 2001-10-16 | 2001-12-05 | Celltech R&D Ltd | Chemical compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3541101A (en) * | 1966-03-04 | 1970-11-17 | Upjohn Co | Isoxazolo(5,4-b)pwridines,5,6 - polymethyleneisoxazolo(5,4 - b)pyridines and processes therefor |
| US3381016A (en) * | 1966-03-04 | 1968-04-30 | Upjohn Co | Isoxazolo[5, 4-b]pyridine derivatives and a method for their preparation |
| US3816429A (en) * | 1971-08-10 | 1974-06-11 | Ciba Geigy Corp | Tetrahydroisoxazolo(5,4-c)isoquinolines |
| IT1054655B (it) * | 1975-08-27 | 1981-11-30 | Lepetit Spa | Derivati condensati del l isochinolina |
-
1983
- 1983-03-10 AU AU12330/83A patent/AU561013B2/en not_active Ceased
- 1983-03-10 GR GR70751A patent/GR77945B/el unknown
- 1983-03-14 ZA ZA831738A patent/ZA831738B/xx unknown
- 1983-03-14 PH PH28645A patent/PH18337A/en unknown
- 1983-03-17 AT AT83102648T patent/ATE30425T1/de not_active IP Right Cessation
- 1983-03-17 EP EP83102648A patent/EP0090275B1/de not_active Expired
- 1983-03-17 DE DE8383102648T patent/DE3374199D1/de not_active Expired
- 1983-03-18 IL IL68171A patent/IL68171A/xx unknown
- 1983-03-28 JP JP58050590A patent/JPS58177992A/ja active Granted
- 1983-03-28 US US06/479,378 patent/US4530927A/en not_active Expired - Fee Related
- 1983-03-29 CA CA000424793A patent/CA1204440A/en not_active Expired
- 1983-03-29 ES ES521083A patent/ES8405407A1/es not_active Expired
- 1983-03-29 DK DK143583A patent/DK143583A/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL68171A0 (en) | 1983-06-15 |
| JPS58177992A (ja) | 1983-10-18 |
| ES521083A0 (es) | 1984-06-01 |
| JPH0342276B2 (de) | 1991-06-26 |
| ATE30425T1 (de) | 1987-11-15 |
| ZA831738B (en) | 1984-01-25 |
| DK143583D0 (da) | 1983-03-29 |
| IL68171A (en) | 1986-03-31 |
| PH18337A (en) | 1985-06-05 |
| EP0090275A3 (en) | 1984-05-02 |
| CA1204440A (en) | 1986-05-13 |
| EP0090275B1 (de) | 1987-10-28 |
| ES8405407A1 (es) | 1984-06-01 |
| DK143583A (da) | 1983-10-01 |
| GR77945B (de) | 1984-09-25 |
| US4530927A (en) | 1985-07-23 |
| AU561013B2 (en) | 1987-04-30 |
| AU1233083A (en) | 1983-10-06 |
| EP0090275A2 (de) | 1983-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |