DE3369516D1 - Novel 3-(2-(azabicyclo) ethyl)1,2,3,4-tetrahydro-5h(1)benzopyrano(3,4-c)pyridin-5-ones, pharmaceutical compositions containing them and processes for their production - Google Patents
Novel 3-(2-(azabicyclo) ethyl)1,2,3,4-tetrahydro-5h(1)benzopyrano(3,4-c)pyridin-5-ones, pharmaceutical compositions containing them and processes for their productionInfo
- Publication number
- DE3369516D1 DE3369516D1 DE8383303557T DE3369516T DE3369516D1 DE 3369516 D1 DE3369516 D1 DE 3369516D1 DE 8383303557 T DE8383303557 T DE 8383303557T DE 3369516 T DE3369516 T DE 3369516T DE 3369516 D1 DE3369516 D1 DE 3369516D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- radical
- carbon atoms
- benzopyrano
- azabicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 239000004044 bronchoconstricting agent Substances 0.000 abstract 1
- 230000002741 bronchospastic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/391,197 US4404138A (en) | 1982-06-22 | 1982-06-22 | 3-[2-(Azabicyclo) ethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3369516D1 true DE3369516D1 (en) | 1987-03-05 |
Family
ID=23545658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383303557T Expired DE3369516D1 (en) | 1982-06-22 | 1983-06-21 | Novel 3-(2-(azabicyclo) ethyl)1,2,3,4-tetrahydro-5h(1)benzopyrano(3,4-c)pyridin-5-ones, pharmaceutical compositions containing them and processes for their production |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4404138A (cs) |
| EP (1) | EP0101162B1 (cs) |
| JP (1) | JPS5980680A (cs) |
| AT (1) | ATE25257T1 (cs) |
| AU (1) | AU539572B2 (cs) |
| CA (1) | CA1191847A (cs) |
| DE (1) | DE3369516D1 (cs) |
| DK (1) | DK283583A (cs) |
| ES (1) | ES523461A0 (cs) |
| GR (1) | GR78623B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101928505B1 (ko) * | 2011-01-28 | 2018-12-12 | 에스케이바이오팜 주식회사 | 피리돈 유도체 및 이를 포함하는 약학적 조성물 |
| KR101925971B1 (ko) | 2011-01-28 | 2018-12-06 | 에스케이바이오팜 주식회사 | 피리돈 유도체 및 이를 포함하는 약학적 조성물 |
| WO2014176348A1 (en) * | 2013-04-23 | 2014-10-30 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Inhibitors of the ire-1/xbp-1 pathway and methods of using thereof |
| WO2018097162A1 (ja) * | 2016-11-24 | 2018-05-31 | 第一三共株式会社 | クマリン骨格を有するスルホンアミド誘導体 |
| JP7648538B2 (ja) * | 2019-04-27 | 2025-03-18 | ヘルス リサーチ インコーポレイテッド | 前立腺癌の治療のためのクマリン修飾アンドロゲン |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661919A (en) * | 1969-03-27 | 1972-05-09 | Little Inc A | Tetrahydropyridyl-5-resorcinols |
| US3914237A (en) * | 1969-10-30 | 1975-10-21 | Little Inc A | 5H{8 1{9 benzopyrano-{8 3,4-c{9 piperidines |
| US3689497A (en) * | 1971-03-09 | 1972-09-05 | Warner Lambert Co | Substituted benzopyrano (3,4-b) pyridines and process for their preparation |
| US3946008A (en) * | 1973-03-21 | 1976-03-23 | Warner-Lambert Company | Substituted benzopyrano[3,4-c]pyridines |
| US3991196A (en) * | 1974-12-19 | 1976-11-09 | Warner-Lambert Company | Novel substituted benzopyranopyridine hexahydro azepine containing benzopyrano[3,4-c]pyridines |
| US4018766A (en) * | 1974-12-19 | 1977-04-19 | Warner-Lambert Company | Substituted benzopyrano[3,4-c]pyridine-5-ones |
| US4013671A (en) * | 1975-01-03 | 1977-03-22 | Warner-Lambert Company | Substituted benzopyrano[3,4-c]pyridines and process for their preparation |
| US4276296A (en) * | 1975-02-10 | 1981-06-30 | Warner-Lambert Company | Substituted benzopyrano[3,4-c]pyridines, compositions and use thereof |
| US4117140A (en) * | 1975-02-10 | 1978-09-26 | Brown Richard E | Bronchodilating piperidinoethyl benzopyranopyridinones |
-
1982
- 1982-06-22 US US06/391,197 patent/US4404138A/en not_active Expired - Fee Related
-
1983
- 1983-06-08 CA CA000429977A patent/CA1191847A/en not_active Expired
- 1983-06-09 AU AU15659/83A patent/AU539572B2/en not_active Ceased
- 1983-06-20 DK DK283583A patent/DK283583A/da not_active Application Discontinuation
- 1983-06-20 GR GR71724A patent/GR78623B/el unknown
- 1983-06-21 EP EP83303557A patent/EP0101162B1/en not_active Expired
- 1983-06-21 ES ES523461A patent/ES523461A0/es active Granted
- 1983-06-21 AT AT83303557T patent/ATE25257T1/de not_active IP Right Cessation
- 1983-06-21 JP JP58110311A patent/JPS5980680A/ja active Pending
- 1983-06-21 DE DE8383303557T patent/DE3369516D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES8500949A1 (es) | 1984-11-01 |
| AU539572B2 (en) | 1984-10-04 |
| US4404138A (en) | 1983-09-13 |
| AU1565983A (en) | 1984-01-05 |
| DK283583D0 (da) | 1983-06-20 |
| GR78623B (cs) | 1984-09-27 |
| EP0101162A3 (en) | 1984-09-05 |
| ES523461A0 (es) | 1984-11-01 |
| DK283583A (da) | 1983-12-23 |
| EP0101162B1 (en) | 1987-01-28 |
| CA1191847A (en) | 1985-08-13 |
| EP0101162A2 (en) | 1984-02-22 |
| ATE25257T1 (de) | 1987-02-15 |
| JPS5980680A (ja) | 1984-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |