DE3368416D1 - Aroyl pyrrolizine compounds, process for their preparation and pharmaceutical compositions containing them - Google Patents

Aroyl pyrrolizine compounds, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
DE3368416D1
DE3368416D1 DE8383300536T DE3368416T DE3368416D1 DE 3368416 D1 DE3368416 D1 DE 3368416D1 DE 8383300536 T DE8383300536 T DE 8383300536T DE 3368416 T DE3368416 T DE 3368416T DE 3368416 D1 DE3368416 D1 DE 3368416D1
Authority
DE
Germany
Prior art keywords
aroyl
preparation
pharmaceutical compositions
compositions containing
pyrrolizine compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383300536T
Other languages
English (en)
Inventor
Alexander Crossan Goudie
Robert William Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE3368416D1 publication Critical patent/DE3368416D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8383300536T 1982-02-25 1983-02-03 Aroyl pyrrolizine compounds, process for their preparation and pharmaceutical compositions containing them Expired DE3368416D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8205546 1982-02-25

Publications (1)

Publication Number Publication Date
DE3368416D1 true DE3368416D1 (en) 1987-01-29

Family

ID=10528598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383300536T Expired DE3368416D1 (en) 1982-02-25 1983-02-03 Aroyl pyrrolizine compounds, process for their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
EP (1) EP0091181B1 (de)
JP (1) JPS58157789A (de)
AU (1) AU1176983A (de)
CA (1) CA1194026A (de)
DE (1) DE3368416D1 (de)
ES (2) ES520076A0 (de)
NZ (1) NZ203371A (de)
ZA (1) ZA831215B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874871A (en) * 1987-03-25 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4232038A (en) * 1979-08-31 1980-11-04 Syntex (U.S.A.) Inc. 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3H-pyrrolo[1,]pyrrole-1-carboxylic acids
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters

Also Published As

Publication number Publication date
ES8504803A1 (es) 1985-05-01
NZ203371A (en) 1986-05-09
ES526400A0 (es) 1985-10-01
ES520076A0 (es) 1985-05-01
ZA831215B (en) 1984-04-25
EP0091181A2 (de) 1983-10-12
JPS58157789A (ja) 1983-09-19
EP0091181B1 (de) 1986-12-17
CA1194026A (en) 1985-09-24
AU1176983A (en) 1983-09-01
EP0091181A3 (en) 1984-07-11
ES8600292A1 (es) 1985-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee