DE3274641D1 - Octahydrobenzo(6,7)cyclohept(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them - Google Patents

Octahydrobenzo(6,7)cyclohept(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them

Info

Publication number
DE3274641D1
DE3274641D1 DE8282110410T DE3274641T DE3274641D1 DE 3274641 D1 DE3274641 D1 DE 3274641D1 DE 8282110410 T DE8282110410 T DE 8282110410T DE 3274641 T DE3274641 T DE 3274641T DE 3274641 D1 DE3274641 D1 DE 3274641D1
Authority
DE
Germany
Prior art keywords
cyclohept
octahydrobenzo
oxazines
preparation
pharmaceutical formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282110410T
Other languages
English (en)
Inventor
James H Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3274641D1 publication Critical patent/DE3274641D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8282110410T 1981-11-20 1982-11-11 Octahydrobenzo(6,7)cyclohept(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them Expired DE3274641D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/323,771 US4349548A (en) 1981-11-20 1981-11-20 Octahydrobenzo[6,7]cyclohept[1,2-b]-1,4-oxazines, compositions and use

Publications (1)

Publication Number Publication Date
DE3274641D1 true DE3274641D1 (en) 1987-01-22

Family

ID=23260649

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282110410T Expired DE3274641D1 (en) 1981-11-20 1982-11-11 Octahydrobenzo(6,7)cyclohept(1,2-b)-1,4-oxazines, process for their preparation and pharmaceutical formulation containing them

Country Status (4)

Country Link
US (1) US4349548A (de)
EP (1) EP0080116B1 (de)
JP (1) JPS5892671A (de)
DE (1) DE3274641D1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766212A (en) * 1983-02-15 1988-08-23 Merrell Dow Pharmaceuticals Inc. 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives
US4774243A (en) * 1985-12-24 1988-09-27 Merck & Co., Inc. Dopamine agonists for treating elevated intraocular pressure
US4758661A (en) * 1986-06-24 1988-07-19 Merck & Co., Inc. Chiral synthesis of (+)-trans-1a,2,3,4a,5,6-hexahydro-9-hydroxy-4-propyl-4H-naphth[1,2-b]-1,4-oxazine
IT1283110B1 (it) * 1996-06-07 1998-04-07 Indena Spa Composti a scheletro colchicinico,loro uso come farmaci e composizioni che li contengono
DE202014008299U1 (de) 2014-10-17 2015-03-10 Hartmann Möbelwerke GmbH Stuhl

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476649A1 (fr) * 1980-02-26 1981-08-28 Roussel Uclaf Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Also Published As

Publication number Publication date
JPS5892671A (ja) 1983-06-02
US4349548A (en) 1982-09-14
EP0080116A2 (de) 1983-06-01
EP0080116A3 (en) 1984-07-25
EP0080116B1 (de) 1986-12-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee