DE3270869D1 - Dihydrothiazole-purines - Google Patents

Dihydrothiazole-purines

Info

Publication number
DE3270869D1
DE3270869D1 DE8282107863T DE3270869T DE3270869D1 DE 3270869 D1 DE3270869 D1 DE 3270869D1 DE 8282107863 T DE8282107863 T DE 8282107863T DE 3270869 T DE3270869 T DE 3270869T DE 3270869 D1 DE3270869 D1 DE 3270869D1
Authority
DE
Germany
Prior art keywords
lower alkyl
dihydrothiazole
purines
halogen
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282107863T
Other languages
English (en)
Inventor
John Winthrop Hadden
Lionel Norton Simon
Alfredo Giner-Sorolla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NEWPORT PHARMACEUTICALS
Sloan Kettering Institute for Cancer Research
Newport Pharmaceuticals International Inc
Original Assignee
NEWPORT PHARMACEUTICALS
Sloan Kettering Institute for Cancer Research
Newport Pharmaceuticals International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NEWPORT PHARMACEUTICALS, Sloan Kettering Institute for Cancer Research, Newport Pharmaceuticals International Inc filed Critical NEWPORT PHARMACEUTICALS
Application granted granted Critical
Publication of DE3270869D1 publication Critical patent/DE3270869D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8282107863T 1981-08-26 1982-08-26 Dihydrothiazole-purines Expired DE3270869D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/296,557 US4387226A (en) 1981-08-26 1981-08-26 Purine-dihydrothiazoles

Publications (1)

Publication Number Publication Date
DE3270869D1 true DE3270869D1 (de) 1986-06-05

Family

ID=23142521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282107863T Expired DE3270869D1 (de) 1981-08-26 1982-08-26 Dihydrothiazole-purines

Country Status (7)

Country Link
US (1) US4387226A (de)
EP (1) EP0073490B1 (de)
JP (1) JPS5843981A (de)
AT (1) ATE19519T1 (de)
AU (1) AU554372B2 (de)
DE (1) DE3270869D1 (de)
IN (1) IN158143B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US6057329A (en) * 1996-12-23 2000-05-02 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives
RU2660653C1 (ru) * 2017-05-29 2018-07-09 Федеральное государственное бюджетное образовательное учреждение высшего образования "Сибирский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СибГМУ Минздрава России) Способ получения 1,3-диметил-7-(пиперидин-1-илметил)-6,7-дигидротиазоло[3,2-f]пурин-2,4(1н,3н)-диона

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2592930A (en) * 1952-04-15 Method for preparing vitamin b
US2592931A (en) * 1952-04-15 Thiothiazolone derivatives
US3770741A (en) * 1968-01-05 1973-11-06 Pfizer 1,3-dimethyl - 1,2,3,4 - tetrahydroheterocyclo(x,y-f)purine-2,4-diones and method for their preparation
US3637684A (en) * 1968-01-05 1972-01-25 Pfizer Preparation of heterocycloimidazoles
BE755361A (fr) * 1969-08-28 1971-03-01 Newport Pharmaceuticals Derives de l'inosine
JPS516992A (ja) * 1974-07-03 1976-01-20 Dainippon Pharmaceutical Co Jihidorochiazoroadeninjudotaino seiho

Also Published As

Publication number Publication date
AU554372B2 (en) 1986-08-21
EP0073490B1 (de) 1986-04-30
JPH0435476B2 (de) 1992-06-11
ATE19519T1 (de) 1986-05-15
IN158143B (de) 1986-09-13
JPS5843981A (ja) 1983-03-14
EP0073490A1 (de) 1983-03-09
US4387226A (en) 1983-06-07
AU1215183A (en) 1984-09-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee