DE3266036D1 - 3-piperidinylindole derivatives, their salts and preparation, their use in medicines and pharmaceutical preparations containing them - Google Patents

3-piperidinylindole derivatives, their salts and preparation, their use in medicines and pharmaceutical preparations containing them

Info

Publication number
DE3266036D1
DE3266036D1 DE8282401357T DE3266036T DE3266036D1 DE 3266036 D1 DE3266036 D1 DE 3266036D1 DE 8282401357 T DE8282401357 T DE 8282401357T DE 3266036 T DE3266036 T DE 3266036T DE 3266036 D1 DE3266036 D1 DE 3266036D1
Authority
DE
Germany
Prior art keywords
carbon atoms
alkyl
hydrogen
group
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282401357T
Other languages
German (de)
English (en)
Inventor
Lucien Nedelec
Jacques Guillaume
Claude Dumont
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of DE3266036D1 publication Critical patent/DE3266036D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8282401357T 1981-07-24 1982-07-21 3-piperidinylindole derivatives, their salts and preparation, their use in medicines and pharmaceutical preparations containing them Expired DE3266036D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8114428A FR2510111A1 (fr) 1981-07-24 1981-07-24 Nouveaux derives du piperidin-3-yl indole, leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
DE3266036D1 true DE3266036D1 (en) 1985-10-10

Family

ID=9260844

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282401357T Expired DE3266036D1 (en) 1981-07-24 1982-07-21 3-piperidinylindole derivatives, their salts and preparation, their use in medicines and pharmaceutical preparations containing them

Country Status (7)

Country Link
US (1) US4447438A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0071520B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5824580A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE15370T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1195332A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3266036D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2510111A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026869A (en) * 1984-02-06 1991-06-25 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
FR2567884B1 (fr) * 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
FR2610929B1 (fr) * 1987-02-13 1989-06-23 Roussel Uclaf Derives de la benzimidazol-2-one, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
FI970310A0 (fi) * 1994-07-26 1997-01-24 Pfizer 4-indolijohdannaiset serotoniinin vaikuttaja- ja vastavaikuttaja-aineina
RU2415138C2 (ru) * 2005-07-13 2011-03-27 Ф. Хоффманн-Ля Рош Аг Производные бензимидазола и индола в качестве селективных антагонистов 5-нт6 и/или 5-нт2а рецепторов
SG11201606216UA (en) 2014-04-23 2016-09-29 Dart Neuroscience Llc Substituted [1,2,4] triazolo [1,5-a] pyrimidin-7-yl compounds as pde2 inhibitors
TWI568737B (zh) 2014-11-05 2017-02-01 達特神經科學（開曼）有限責任公司 作為ｐｄｅ２抑制劑之經取代的５－甲基－［１，２，４］三唑并［１，５－ａ］嘧啶－２－胺化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1030623A (en) * 1962-01-17 1966-05-25 Upjohn Co 3-substituted-indoles and their preparation
US3501484A (en) * 1968-01-15 1970-03-17 Miles Lab Certain substituted 3 - (2-indolyl)-1,2,5,6-tetrahydropyridines and derivatives thereof
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2391211A2 (fr) * 1977-05-18 1978-12-15 Roussel Uclaf Nouveaux derives de 2,3-dihydroa(4-(3-indolyl) 1-piperidinyl) methyl 1,4-benzodioxin-2-methanol, un procede de preparation, et leur application comme medicaments
US4332808A (en) * 1979-06-12 1982-06-01 Roussel Uclaf Dopaminergically stimulating 4-substituted indoles
FR2458549A1 (fr) * 1979-06-12 1981-01-02 Roussel Uclaf Nouveaux derives de l'indole, leur procede de preparation et leur application comme medicaments
SE8004129L (sv) * 1979-07-13 1981-01-14 Roussel Uclaf Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar

Also Published As

Publication number Publication date
JPS5824580A (ja) 1983-02-14
FR2510111A1 (fr) 1983-01-28
EP0071520B1 (fr) 1985-09-04
ATE15370T1 (de) 1985-09-15
CA1195332A (fr) 1985-10-15
US4447438A (en) 1984-05-08
JPH0339071B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-06-12
FR2510111B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-12-30
EP0071520A1 (fr) 1983-02-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee