DE3264523D1 - Derivatives of 4-aminoethoxy-5-isopropyl-2-methyl phenol, process for their preparation and their use as medicines - Google Patents
Derivatives of 4-aminoethoxy-5-isopropyl-2-methyl phenol, process for their preparation and their use as medicinesInfo
- Publication number
- DE3264523D1 DE3264523D1 DE8282450006T DE3264523T DE3264523D1 DE 3264523 D1 DE3264523 D1 DE 3264523D1 DE 8282450006 T DE8282450006 T DE 8282450006T DE 3264523 T DE3264523 T DE 3264523T DE 3264523 D1 DE3264523 D1 DE 3264523D1
- Authority
- DE
- Germany
- Prior art keywords
- aminoethoxy
- medicines
- isopropyl
- derivatives
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YIQNPWXJLJNNTB-UHFFFAOYSA-N 4-(2-aminoethoxy)-2-methyl-5-propan-2-ylphenol Chemical class CC(C)C1=CC(O)=C(C)C=C1OCCN YIQNPWXJLJNNTB-UHFFFAOYSA-N 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8106832A FR2503142A1 (en) | 1981-04-06 | 1981-04-06 | N-Substd. 4-aminoethoxy-2-methyl-5-isopropyl-phenol derivs. - useful as alpha blockers and platelet aggregation inhibitors |
FR8203796A FR2522502A2 (fr) | 1982-03-04 | 1982-03-04 | Application d'aminoethoxy-4 isopropyl-5 methyl-2 phenols diversement substitues au traitement et a la prevention des thromboses |
FR8203795A FR2522654A2 (fr) | 1982-03-04 | 1982-03-04 | Nouveaux aminoethoxy-4 isopropyl-5 methyl-2 phenols diversement substitues, leur methode de synthese, les preparations pharmaceutiques les contenant et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3264523D1 true DE3264523D1 (en) | 1985-08-08 |
Family
ID=27251046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8282450006T Expired DE3264523D1 (en) | 1981-04-06 | 1982-04-01 | Derivatives of 4-aminoethoxy-5-isopropyl-2-methyl phenol, process for their preparation and their use as medicines |
Country Status (7)
Country | Link |
---|---|
US (1) | US4818772A (de) |
EP (1) | EP0062596B1 (de) |
CA (1) | CA1196650A (de) |
DE (1) | DE3264523D1 (de) |
ES (1) | ES8304062A1 (de) |
OA (1) | OA07063A (de) |
PT (1) | PT74710B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0179009A1 (de) * | 1984-09-19 | 1986-04-23 | Cortial S.A. | N-1(Aminoalcoxy)-4-isopropyl-5 phenoxy)-2 ethyl-N-4-phenylpiperazine, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung |
FR2585355B2 (fr) * | 1985-07-26 | 1988-11-25 | Cortial | Nouvelles n1-((aminoalcoxy)-4 isopropyl-5 methyl-2 phenoxy)-2 ethyl n4-phenyl piperazines, leur methode de preparation et leur application therapeutique |
FR2570376B1 (fr) * | 1984-09-19 | 1987-09-25 | Cortial | Nouveaux (isopropyl-5 (((methoxy-2 phenyl) piperazinyl)-2 ethoxy)-4 methyl-2 phenoxy)-1 alkylamino-3 propanols-2, leur methode de preparation et leur application therapeutique |
FR2574401B1 (fr) * | 1984-12-12 | 1987-01-09 | Cortial | Bis-((hydroxy-4 isopropyl-2 methyl-5 phenoxy)-2 ethyl) amines, leur methode de synthese, les preparations pharmaceutiques les contenant et leur application en therapeutique |
FR2581643B1 (fr) * | 1985-05-10 | 1988-11-18 | Irceba | Compositions pharmaceutiques utiles dans le domaine de l'urologie, contenant de l'acetoxy-1 methyl-2 ((piperidino)-2 ethoxy)-4 (methyl-1 ethyl)-5 benzene ou l'un de ses sels |
FR2614302B2 (fr) * | 1986-02-10 | 1989-07-28 | Irceba | Derives du ((pyrrolidinul-1)-2 ethoxy)-5 p-cymene, procede pour leur preparation et medicaments en contenant. |
FR2594122B1 (fr) * | 1986-02-10 | 1988-06-10 | Irceba | ((pyrrolidinyl-1)-2 ethyoxy)-3 p cymene, les derives acetyl, acetoxy, hydroxy dudit produit et les medicaments contenant lesdits composes comme principe actif |
FR2595357B1 (fr) * | 1986-03-04 | 1988-07-08 | Irceba | (piperidino-3 propoxy)-5 p.cymene, les derives acetyl, acetoxy et hydroxy dudit produit, les sels de ces produits, un procede de preparation desdits produits et les medicaments contenant au moins un de ces produits comme principe actif |
ATE74600T1 (de) * | 1987-04-30 | 1992-04-15 | Inst Rech Chim Biolog | Derivate von 5-(2-(1-pyrrolidinyl)-aethoxy>-pcymen, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel. |
IT1224404B (it) * | 1987-12-23 | 1990-10-04 | Simes | Composti attivi sul sistema cardiovascolare |
JP2706755B2 (ja) * | 1994-02-10 | 1998-01-28 | 日本たばこ産業株式会社 | 新規なベンジルアミノエトキシベンゼン誘導体 |
US6730691B1 (en) | 2000-02-10 | 2004-05-04 | Miles A. Galin | Uses of alpha adrenergic blocking agents |
KR20040014600A (ko) * | 2001-07-02 | 2004-02-14 | 산텐 세이야꾸 가부시키가이샤 | 알파1 수용체 차단약을 유효 성분으로 하는 시신경 보호제 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2688639A (en) * | 1951-07-17 | 1954-09-07 | Givaudan Corp | Nu-(beta-phenoxyethyl) ethanolamines |
US2688638A (en) * | 1951-07-17 | 1954-09-07 | Givaudan Corp | Nu-(beta-phenoxyethyl) haloethylamines |
GB745070A (en) * | 1953-04-28 | 1956-02-22 | Veritas Drug Company Ltd | Improvements in or relating to basic thymol dimethyl-amino ethyl ethers |
FR1310M (fr) * | 1959-04-22 | 1962-05-14 | Pfizer | Agents thérapeutiques appartenant au groupe des anisoxyéthylamines. |
GB902617A (en) * | 1959-04-22 | 1962-08-01 | Pfizer Ltd | Improvements in or relating to therapeutically-active alkylamines |
GB922600A (en) * | 1960-05-06 | 1963-04-03 | Crookes Lab Ltd | Ortho-tertiary-butyl phenolethers |
FR1405494A (fr) * | 1963-06-20 | 1965-07-09 | Ward Blenkinsop & Co Ltd | 1.4-benzodioxannes et leur préparation |
US3341572A (en) * | 1965-05-26 | 1967-09-12 | Warner Lambert Pharmaceutical | Basic thymol n-ethyl-n-betahaloethyl-aminoethyl ethers |
GB1301134A (en) * | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
US3988475A (en) * | 1974-02-05 | 1976-10-26 | Istituto Luso Farmaco D'italia S.R.L. | Phenoxyalkylamines |
HU170392B (de) * | 1974-07-19 | 1977-06-28 | ||
US4147805A (en) * | 1978-07-28 | 1979-04-03 | Mead Johnson & Company | Alkylthiophenoxyalkylamines and the pharmaceutical use thereof |
IT1209160B (it) * | 1979-12-20 | 1989-07-10 | Blasinachim Spa | Processo per la sintesi di 4-[2-(dimetilammino)-etossi]2-metil-5-81-metiletil)-fenol-este ri |
-
1982
- 1982-04-01 DE DE8282450006T patent/DE3264523D1/de not_active Expired
- 1982-04-01 EP EP82450006A patent/EP0062596B1/de not_active Expired
- 1982-04-05 CA CA000400482A patent/CA1196650A/fr not_active Expired
- 1982-04-05 PT PT74710A patent/PT74710B/pt not_active IP Right Cessation
- 1982-04-06 ES ES511220A patent/ES8304062A1/es not_active Expired
- 1982-04-06 OA OA57651A patent/OA07063A/xx unknown
- 1982-04-09 US US06/366,133 patent/US4818772A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT74710B (fr) | 1983-11-09 |
EP0062596A1 (de) | 1982-10-13 |
CA1196650A (fr) | 1985-11-12 |
EP0062596B1 (de) | 1985-07-03 |
ES511220A0 (es) | 1983-02-16 |
OA07063A (fr) | 1984-01-31 |
ES8304062A1 (es) | 1983-02-16 |
PT74710A (fr) | 1982-05-01 |
US4818772A (en) | 1989-04-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |