DE3264033D1 - Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives - Google Patents

Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives

Info

Publication number
DE3264033D1
DE3264033D1 DE8282401299T DE3264033T DE3264033D1 DE 3264033 D1 DE3264033 D1 DE 3264033D1 DE 8282401299 T DE8282401299 T DE 8282401299T DE 3264033 T DE3264033 T DE 3264033T DE 3264033 D1 DE3264033 D1 DE 3264033D1
Authority
DE
Germany
Prior art keywords
derivatives
preparation
benzothiazolesulfonamide
compositions containing
ophthalmic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282401299T
Other languages
English (en)
Inventor
Otto W Woltersdorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3264033D1 publication Critical patent/DE3264033D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70—Sulfur atoms
    • C07D277/76—Sulfur atoms attached to a second hetero atom
    • C07D277/80—Sulfur atoms attached to a second hetero atom to a nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE8282401299T 1981-07-13 1982-07-09 Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives Expired DE3264033D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28247081A 1981-07-13 1981-07-13
US35240082A 1982-02-25 1982-02-25

Publications (1)

Publication Number Publication Date
DE3264033D1 true DE3264033D1 (en) 1985-07-11

Family

ID=26961471

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282401299T Expired DE3264033D1 (en) 1981-07-13 1982-07-09 Benzothiazolesulfonamide derivatives, their preparation and ophthalmic compositions containing said derivatives

Country Status (14)

Country Link
EP (1) EP0070239B1 (de)
AR (1) AR241136A1 (de)
AU (1) AU556363B2 (de)
CA (1) CA1185980A (de)
DE (1) DE3264033D1 (de)
DK (1) DK312082A (de)
ES (1) ES513831A0 (de)
FI (1) FI78080C (de)
GR (1) GR76527B (de)
IE (1) IE53868B1 (de)
IL (1) IL66238A0 (de)
NO (1) NO157538C (de)
NZ (1) NZ201157A (de)
PT (1) PT75229B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5095026A (en) * 1983-02-04 1992-03-10 University Of Iowa Research Foundation Prodrugs of carbonic anhydrase inhibitors
US4500538A (en) * 1983-03-14 1985-02-19 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4499103A (en) * 1983-03-17 1985-02-12 Merck & Co., Inc. Benzothiazole-2-sulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4472418A (en) * 1983-04-22 1984-09-18 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4470991A (en) * 1983-04-22 1984-09-11 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4456599A (en) * 1983-04-22 1984-06-26 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
US4472417A (en) * 1983-04-22 1984-09-18 Merck & Co., Inc. Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure
ES8600752A1 (es) * 1983-06-20 1985-10-16 Merck & Co Inc Un procedimiento para la preparacion de nuevos derivados de tiosulfonamida.
IL72070A (en) * 1983-06-20 1988-11-30 Merck & Co Inc 2-sulfamoylbenzo(b)-thiophene derivatives,their preparation and pharmaceutical compositions containing them
US4544667A (en) * 1984-02-09 1985-10-01 Merck & Co., Inc. 2-Sulfamoylbenzo[b]furan derivatives for the treatment of elevated intraocular pressure
DE3576498D1 (de) * 1984-03-14 1990-04-19 Merck & Co Inc 2-sulfamoyl-1h-indole-derivate zur behandlung von hohem intraocularem druck.
US5059613A (en) * 1990-03-19 1991-10-22 Research Corporation Technologies, Inc. Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors
US5519040A (en) * 1994-04-29 1996-05-21 Allergan Substituted thiazole sulfonamides as antiglaucoma agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2595334A (en) * 1950-04-08 1952-05-06 American Cyanamid Co Benzothiazolesulfonamides and method of preparing the same
US2868800A (en) * 1954-10-13 1959-01-13 Upjohn Co 6-ethoxybenzothiazole-2-sulfonamide

Also Published As

Publication number Publication date
EP0070239A1 (de) 1983-01-19
PT75229A (en) 1982-08-01
FI78080B (fi) 1989-02-28
NO822410L (no) 1983-01-14
PT75229B (en) 1985-10-04
EP0070239B1 (de) 1985-06-05
AU556363B2 (en) 1986-10-30
IE53868B1 (en) 1989-03-29
DK312082A (da) 1983-01-14
AR241136A1 (es) 1991-11-29
FI78080C (fi) 1989-06-12
ES8400417A1 (es) 1983-11-01
IE821668L (en) 1983-01-13
AU8577582A (en) 1983-01-20
ES513831A0 (es) 1983-11-01
FI822464A0 (fi) 1982-07-09
NO157538C (no) 1988-04-06
NO157538B (no) 1987-12-28
NZ201157A (en) 1985-02-28
AR241136A2 (es) 1991-11-29
IL66238A0 (en) 1982-11-30
GR76527B (de) 1984-08-10
CA1185980A (en) 1985-04-23
FI822464L (fi) 1983-01-14

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee