DE3263327D1 - Immune adsorbent, adsorbing device and blood purifying apparatus - Google Patents

Immune adsorbent, adsorbing device and blood purifying apparatus

Info

Publication number
DE3263327D1
DE3263327D1 DE8282100371T DE3263327T DE3263327D1 DE 3263327 D1 DE3263327 D1 DE 3263327D1 DE 8282100371 T DE8282100371 T DE 8282100371T DE 3263327 T DE3263327 T DE 3263327T DE 3263327 D1 DE3263327 D1 DE 3263327D1
Authority
DE
Germany
Prior art keywords
purifying apparatus
adsorbing device
blood purifying
immune adsorbent
adsorbent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282100371T
Other languages
English (en)
Inventor
Naokuni Yamawaki
Shozo Suzuki
Tadaaki Furuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Medical Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56007152A external-priority patent/JPS57122875A/ja
Priority claimed from JP56112919A external-priority patent/JPS5815924A/ja
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Application granted granted Critical
Publication of DE3263327D1 publication Critical patent/DE3263327D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3616—Batch-type treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3253—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure not containing any of the heteroatoms nitrogen, oxygen or sulfur, e.g. aromatic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
DE8282100371T 1981-01-22 1982-01-20 Immune adsorbent, adsorbing device and blood purifying apparatus Expired DE3263327D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56007152A JPS57122875A (en) 1981-01-22 1981-01-22 Immunity adsorbing material and adsorbing device
JP56112919A JPS5815924A (ja) 1981-07-21 1981-07-21 免疫吸着材

Publications (1)

Publication Number Publication Date
DE3263327D1 true DE3263327D1 (en) 1985-06-05

Family

ID=26341414

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282100371T Expired DE3263327D1 (en) 1981-01-22 1982-01-20 Immune adsorbent, adsorbing device and blood purifying apparatus

Country Status (3)

Country Link
US (1) US4432871A (de)
EP (1) EP0056977B1 (de)
DE (1) DE3263327D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1221307A (en) * 1982-12-02 1987-05-05 Nobutaka Tani Adsorbent and process for preparing the same
US4627915A (en) * 1983-04-06 1986-12-09 Asahi Kasei Kogyo Kabushiki Kaisha Absorbent of autoantibody and immune complexes, adsorbing device and blood purifying apparatus comprising the same
JPS6145773A (ja) * 1984-08-07 1986-03-05 テルモ株式会社 体液浄化材
EP0197521B1 (de) * 1985-04-09 1989-08-02 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Immunoglobulinadsorbent und Adsorptionsvorrichtung
CH663728A5 (fr) * 1985-06-10 1988-01-15 Battelle Memorial Institute Procede de purification de substances bioactives par adsorption biospecifique.
FR2586359B1 (fr) * 1985-08-23 1989-09-08 Commissariat Energie Atomique Support solide a base d'alcool polyvinylique capable d'adsorber les lipoproteines et son utilisation pour la separation des lipoproteines de basse densite presentes dans un liquide tel que du plasma sanguin
US5656163A (en) * 1987-01-30 1997-08-12 Baxter International Inc. Chamber for use in a rotating field to separate blood components
US5370802A (en) * 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US5792372A (en) * 1987-01-30 1998-08-11 Baxter International, Inc. Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma
EP0358758A1 (de) * 1987-04-09 1990-03-21 Terumo Kabushiki Kaisha Mittel zur abtrennung von b-lymphozyten und mittel zur klärung von körperflüssigkeiten
DE3717951C1 (de) * 1987-05-25 1988-11-24 Shanmugam Murugavel Verwendung von Silica-Gel zur Entgiftung von Blut
SE462165B (sv) * 1988-02-26 1990-05-14 Porath Jerker Saett att paa en baerare adsorbera sammansatta proteinkomplex, saerskilt vid biospecifika bestaemningsmetoder
US5286449A (en) * 1988-04-04 1994-02-15 Asahi Medical Co., Ltd. Adsorber module for whole blood treatment and an adsorber apparatus containing the adsorber module
US5593897A (en) * 1988-04-04 1997-01-14 Northwestern University Binding of immune complexes by modified forms of C-reactive protein
CA1325770C (en) * 1988-04-04 1994-01-04 Toru Kuroda Adsorber module for whole blood treatment and an adsorber apparatus containing the adsorber module
US5277701A (en) * 1991-11-15 1994-01-11 Regents Of The University Of Minnesota Treatment of aluimmunization and refractoriness to platelet transfusion by protein A column therapy
US5804079A (en) * 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5549834A (en) * 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US6007725A (en) * 1991-12-23 1999-12-28 Baxter International Inc. Systems and methods for on line collection of cellular blood components that assure donor comfort
US5427695A (en) * 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
DE19623131C2 (de) * 1996-06-10 2001-10-31 Gerhard Harry Scholz Konjugat, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Bindung von Substanzen
CN1220531C (zh) * 2001-01-30 2005-09-28 钟渊化学工业株式会社 能够直接进行血液灌流的体液处理器
US20030150813A1 (en) * 2001-04-12 2003-08-14 Nobuyuki Hayashi Adsorbent device for body fluid treatment
EP1621220B1 (de) * 2003-05-08 2014-11-19 Kaneka Corporation Lipoprotein niederer dichte/fibrinogen adsorbens und gerät für die vollblutbehandlung
JP5036315B2 (ja) * 2004-11-05 2012-09-26 株式会社カネカ 血液接触材料の改質方法、及び顆粒球活性化が抑制された血液接触材料
US20130068691A1 (en) * 2011-08-05 2013-03-21 Henry John Smith Targeted apheresis for the treatment of rheumatoid arthritis and immune disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3442819A (en) * 1965-03-26 1969-05-06 Mount Sinai Hospital Research Molecular sieve coated particulate adsorbent and processes using same
DE1914079A1 (de) * 1969-03-20 1970-10-01 Behringwerke Ag Verfahren zur Isolierung von nativem hochgereinigtem Plasminogen
DE2532883C2 (de) * 1975-07-23 1983-03-24 Hans-Peter Dr. 6906 Leimen Geisen Verfahren und Vorrichtung zur selektiven Gewinnung eines Reaktionspartners einer Immunreaktion aus dem strömenden Blut von lebenden Organismen
NL7703937A (nl) * 1977-04-12 1978-10-16 Organon Teknika Bv Inrichting voorzien van een sorbent voor het zuiveren van bloed; een voor orale toepassing geschikt sorbent en een werkwijze voor vervaar- diging van het sorbent.
US4182750A (en) * 1977-04-21 1980-01-08 Sullivan Thomas E Bloodcompatible functional polymers
DE2827109C2 (de) * 1977-06-24 1986-10-30 Asahi Kasei Kogyo K.K., Osaka Verfahren und Vorrichtung zur Abtrennung von organischen Verbindungen von Plasmaproteinen des Blutes
US4246107A (en) * 1978-03-06 1981-01-20 Asahi Kasei Kogyo Kabushiki Kaisha Separation of lymphocytes from lymphocyte-containing suspension by filtration
DE2840655C2 (de) * 1978-09-19 1982-06-16 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg Vorrichtung zur Blutentgiftung

Also Published As

Publication number Publication date
EP0056977A1 (de) 1982-08-04
EP0056977B1 (de) 1985-05-02
US4432871A (en) 1984-02-21

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: ASAHI MEDICAL CO. LTD., TOKIO/TOKYO, JP