DE3261757D1 - Novel urea derivatives - Google Patents

Novel urea derivatives

Info

Publication number
DE3261757D1
DE3261757D1 DE8282200796T DE3261757T DE3261757D1 DE 3261757 D1 DE3261757 D1 DE 3261757D1 DE 8282200796 T DE8282200796 T DE 8282200796T DE 3261757 T DE3261757 T DE 3261757T DE 3261757 D1 DE3261757 D1 DE 3261757D1
Authority
DE
Germany
Prior art keywords
urea derivatives
novel urea
novel
derivatives
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282200796T
Other languages
English (en)
Inventor
Brian Lee Buckwalter
Thomas Robert Lahann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE3261757D1 publication Critical patent/DE3261757D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q9/00—Preparations for removing hair or for aiding hair removal
    • A61Q9/04—Depilatories
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8282200796T 1981-06-30 1982-06-28 Novel urea derivatives Expired DE3261757D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27897081A 1981-06-30 1981-06-30
US06/381,672 US4460602A (en) 1981-06-30 1982-05-25 Urea derivatives

Publications (1)

Publication Number Publication Date
DE3261757D1 true DE3261757D1 (en) 1985-02-14

Family

ID=26959383

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282200796T Expired DE3261757D1 (en) 1981-06-30 1982-06-28 Novel urea derivatives

Country Status (4)

Country Link
US (1) US4460602A (de)
EP (1) EP0068590B1 (de)
CA (1) CA1191862A (de)
DE (1) DE3261757D1 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013759A (en) * 1985-06-10 1991-05-07 The Procter & Gamble Company Compounds and compositions having anti-inflammatory and analgesic activity
GB2178031B (en) 1985-06-10 1989-07-26 Procter & Gamble Phenylacetic acid amides having anti-inflammatory and analgesic activity
US4689182A (en) * 1985-12-20 1987-08-25 Warner-Lambert Company Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US4990533A (en) * 1985-12-20 1991-02-05 Warner-Lambert Co. Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity
US5099030A (en) * 1987-03-09 1992-03-24 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
US5045565A (en) * 1987-03-09 1991-09-03 The Procter & Gamble Company Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain
CN1021819C (zh) * 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
US5461075A (en) * 1988-06-17 1995-10-24 The Procter & Gamble Company Use of vanilloids for the prevention of lesions due to herpes simplex infections
GR880100400A (el) * 1988-06-21 1990-05-11 Sandoz Ag Μεθοδος παρασκευης παραγωγων θειουριας
US5403868A (en) * 1988-12-23 1995-04-04 Sandoz Ltd. Capsaicin derivatives
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
US5063060A (en) * 1989-12-19 1991-11-05 Cisco Limited Partnership Compositions and method for treating painful, inflammatory or allergic disorders
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
US5405617A (en) * 1991-11-07 1995-04-11 Mcneil-Ppc, Inc. Aliphatic or fatty acid esters as a solventless carrier for pharmaceuticals
US5762963A (en) * 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
GB9519270D0 (en) * 1995-09-21 1995-11-22 Sandoz Pharma Uk Organic compounds
CA2197364A1 (en) * 1996-02-15 1997-08-16 Toshikazu Suzuki Phenol compound and process for preparing the same
WO1998020867A1 (en) * 1996-11-15 1998-05-22 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Pharmaceutical compositions containing vanilloid agonists in combination with vanilloid antagonists
WO1998051290A2 (en) 1997-05-16 1998-11-19 Children's Medical Center Corporation Local anesthetic formulations comprising a site 1 sodium channel blocker combined with a second active agent
US6689399B1 (en) 2000-03-16 2004-02-10 James R. Dickson Transdermal delivery of an anti-inflammatory composition
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
DE60120421T2 (de) * 2000-08-21 2006-12-28 Pacific Corp. Neue (thio)harnstoffverbindungen und arzneimittelkompositionen, die diese enthalten
EP1303483B1 (de) 2000-08-21 2008-04-23 Pacific Corporation Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten
US20030203944A1 (en) * 2000-08-21 2003-10-30 Suh Young Ger Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same
WO2002067966A1 (en) 2001-02-22 2002-09-06 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
GB0105895D0 (en) * 2001-03-09 2001-04-25 Smithkline Beecham Plc Novel compounds
PT1605956E (pt) 2002-12-18 2016-03-09 Centrexion Therapeutics Corp Administração de capsaicinóides para o tratamento da osteoartrite
JP2006514109A (ja) * 2002-12-18 2006-04-27 アルゴルクス ファーマスーティカルズ，インク カプサイシノイドの投与
CA2521925A1 (en) * 2003-04-08 2004-10-28 Algorx Pharmaceuticals, Inc. Preparation and purification of synthetic capsaicin
CA2596194A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
WO2007013811A2 (en) * 2005-07-29 2007-02-01 Quest International Services B.V. N-vanillyl urea derivatives as flavour modulating substances
US7709507B2 (en) * 2006-05-17 2010-05-04 Allergan, Inc. Therapeutic fluoroethyl ureas
US8952152B2 (en) 2009-03-24 2015-02-10 Proteus S.A. Methods for purifying phycotoxins, pharmaceutical compositions containing purified phycotoxins, and methods of use thereof
GB0909768D0 (en) * 2009-06-08 2009-07-22 Nanyang Polytechnic Novel compounds and uses thereof
CN102762185A (zh) * 2010-02-17 2012-10-31 宝洁公司 有效的脱毛剂制品
ATE537808T1 (de) * 2010-03-26 2012-01-15 Procter & Gamble Verfahren zur depilation und depilierausrüstung
WO2011119557A2 (en) * 2010-03-26 2011-09-29 The Procter & Gamble Company Kit and method for removing hair
EP2684468A4 (de) * 2011-03-07 2014-08-27 Ajinomoto Kk Salzgeschmacksverstärker
EP2701807A2 (de) * 2011-04-28 2014-03-05 The Procter and Gamble Company Depilationsverfahren und kit
CA3018668C (en) 2013-03-15 2021-04-13 The Children's Medical Center Corporation Neosaxitoxin combination formulations for prolonged local anesthesia

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2663730A (en) * 1953-09-16 1953-12-22 Ethyl Corp N-alkyl-n'-(p-hydroxyphenyl) ureas
US2960488A (en) * 1958-04-25 1960-11-15 Eastman Kodak Co Poly-alpha-olefins containing substituted ureas
DE1166766B (de) * 1961-08-04 1964-04-02 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen Phenylalkylcarbonsaeureamiden
FR1336388A (fr) * 1961-08-04 1963-08-30 Boehringer Sohn Ingelheim Procédé pour la préparation des amides d'acides phénylalcoylcarboxyliques
BE626897A (de) * 1962-01-17
DE1170398B (de) * 1962-05-30 1964-05-21 Bayer Ag Verfahren zur Herstellung von Isocyanaten
GB1143802A (de) * 1965-03-25
US3488376A (en) * 1967-01-27 1970-01-06 Upjohn Co Isocyanatophenols
US3636104A (en) * 1968-10-29 1972-01-18 Olin Mathieson Process for preparing n n'-diarylthioureas
JPS4913785B1 (de) * 1969-02-10 1974-04-03
US3734961A (en) * 1969-06-25 1973-05-22 Exxon Co Herbicidal fluorinated phenyl ureas and thioureas
JPS4913785Y1 (de) * 1969-08-04 1974-04-05
US3852339A (en) * 1970-06-15 1974-12-03 Squibb & Sons Inc Aminoalkoxyphenylurea derivatives
US3852348A (en) * 1970-11-18 1974-12-03 Stauffer Chemical Co Ether and sulfide meta-substituted phenyl ureas
ES474449A1 (es) * 1978-10-23 1979-05-01 Invest Tecnica Aplicada Procedimiento de obtencion de ureas y tioureas con actividad farmacologica.
US4238508A (en) * 1979-08-17 1980-12-09 The Research Foundation Of State University Of New York Method for analgesia using 3-hydroxyacetanilide
US4313958A (en) * 1980-10-24 1982-02-02 The Procter & Gamble Company Method of producing analgesia
JPS6139413A (ja) * 1984-07-31 1986-02-25 日立電線株式会社 弛度抑制型電線の製造方法
JPS6147752A (ja) * 1984-08-14 1986-03-08 Fujikura Ltd 難燃性組成物

Also Published As

Publication number Publication date
CA1191862A (en) 1985-08-13
EP0068590A1 (de) 1983-01-05
EP0068590B1 (de) 1985-01-02
US4460602A (en) 1984-07-17

Similar Documents

Publication Publication Date Title
DE3261757D1 (en) Novel urea derivatives
AU558623B2 (en) Urea derivatives
GB8417905D0 (en) Hydroxymethyl-5 oxazolidinic derivatives
GB2169294B (en) Urea derivatives
IL65799A0 (en) 2-amino-1-alkanol derivatives
GB2111483B (en) 3-acylamino-4-hydroxy-phenethylamine derivatives
GB2101986B (en) Thiazolinoazetidinone derivatives
IL64774A0 (en) Hexahydro-trans-and tetrahydropyridoindole derivatives
GB2099424B (en) Isoprenylamine derivatives
GB2155932B (en) Phenylhydrazinomethylenemalononitrile derivatives
GB2099419B (en) Imidazothizole derivatives
EG15931A (en) Urea derivatives
GB2098613B (en) Polyisoprenylamine derivatives
GB2094297B (en) Apovincaminol derivatives
GB2099423B (en) Isopyrenylamine derivatives
IL66123A0 (en) Benzoyl-phenyl-piperidine derivatives
GB2112781B (en) Aminopropylaminobleomycin derivatives
EP0066144A3 (en) Benzylazole derivatives
GB2100728B (en) 3-substituted -2- cyclopentenone derivatives
GB2106908B (en) Alkoxyvincamone derivatives
GB2108105B (en) Isoprenylamine derivatives
ZA818413B (en) Indoloquinolizine derivatives
GB2098202B (en) Tetrachloropentene derivatives
GB2096609B (en) Thiazolotriazine derivatives
IE822143L (en) Urea derivatives