DE3171598D1 - Novel beta-lactam compounds, process for production thereof, and medicines containing them - Google Patents

Novel beta-lactam compounds, process for production thereof, and medicines containing them

Info

Publication number
DE3171598D1
DE3171598D1 DE8181107819T DE3171598T DE3171598D1 DE 3171598 D1 DE3171598 D1 DE 3171598D1 DE 8181107819 T DE8181107819 T DE 8181107819T DE 3171598 T DE3171598 T DE 3171598T DE 3171598 D1 DE3171598 D1 DE 3171598D1
Authority
DE
Germany
Prior art keywords
production
lactam compounds
medicines containing
novel beta
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181107819T
Other languages
German (de)
English (en)
Inventor
Mitsuyasu Okabe
Takeo Yoshioka
Yasuo Fukagawa
Rokuro Okamoto
Kageaki Kouno
Tomoyuki Ishikura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55135829A external-priority patent/JPS5762280A/ja
Priority claimed from JP55144507A external-priority patent/JPS5770890A/ja
Priority claimed from JP55170864A external-priority patent/JPS5795987A/ja
Application filed by Sanraku Ocean Co Ltd filed Critical Sanraku Ocean Co Ltd
Application granted granted Critical
Publication of DE3171598D1 publication Critical patent/DE3171598D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8181107819T 1980-10-01 1981-10-01 Novel beta-lactam compounds, process for production thereof, and medicines containing them Expired DE3171598D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP55135829A JPS5762280A (en) 1980-10-01 1980-10-01 Novel antibiotic oa-6129a and its preparation
JP55144507A JPS5770890A (en) 1980-10-17 1980-10-17 Novel antibiotic oa-6129b and its preparation
JP55170864A JPS5795987A (en) 1980-12-05 1980-12-05 Novel antibiotic oa-6129c and its preparation

Publications (1)

Publication Number Publication Date
DE3171598D1 true DE3171598D1 (en) 1985-09-05

Family

ID=27317159

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181107819T Expired DE3171598D1 (en) 1980-10-01 1981-10-01 Novel beta-lactam compounds, process for production thereof, and medicines containing them

Country Status (6)

Country Link
US (1) US4426390A (es)
EP (1) EP0048999B1 (es)
KR (1) KR850000577B1 (es)
CA (1) CA1182413A (es)
DE (1) DE3171598D1 (es)
ES (1) ES505886A0 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068485B1 (en) * 1981-07-01 1987-11-11 Sanraku Incorporated Novel antibiotics and process for production thereof
JPS5857392A (ja) * 1981-10-02 1983-04-05 Sanraku Inc 新規な抗生物質ｏａ−６１２９のリン酸エステル
KR840003255A (ko) * 1982-01-28 1984-08-20 스즈끼 시즈오 항생물질 oa-6129a,b1,b2의 유도체 및 그 제법
US5882900A (en) * 1992-09-10 1999-03-16 Gruppo Lepetit S.P.A. Process for the selective increase of production of antibiotic GE 2270 factor a by adding vitamin B12 to nutrient medium

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
CH632508A5 (de) * 1975-11-21 1982-10-15 Merck & Co Inc Verfahren zur herstellung von neuen estern des n-acylierten thienamycins.
DK456580A (da) * 1979-10-29 1981-06-04 Beecham Group Ltd Fremgangsmaade til fremstilling af bicycliske beta-lactamringholdige forbindelser

Also Published As

Publication number Publication date
CA1182413A (en) 1985-02-12
ES8302093A1 (es) 1983-01-01
ES505886A0 (es) 1983-01-01
US4426390A (en) 1984-01-17
KR850000577B1 (ko) 1985-04-29
KR830007840A (ko) 1983-11-07
EP0048999A1 (en) 1982-04-07
EP0048999B1 (en) 1985-07-31

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER PATENTINHABER LAUTET RICHTIG: SANRAKU INC., TOKIO/TOKYO, JP

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee