DE3165576D1 - 1,1-disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivatives - Google Patents

1,1-disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivatives

Info

Publication number
DE3165576D1
DE3165576D1 DE8181304833T DE3165576T DE3165576D1 DE 3165576 D1 DE3165576 D1 DE 3165576D1 DE 8181304833 T DE8181304833 T DE 8181304833T DE 3165576 T DE3165576 T DE 3165576T DE 3165576 D1 DE3165576 D1 DE 3165576D1
Authority
DE
Germany
Prior art keywords
derivatives
indolo
hexahydro
disubstituted
homo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181304833T
Other languages
German (de)
English (en)
Inventor
Csaba Szantay
Lajos Szabo
Gyorgy Kalaus
Janos Sapi
Janos Kreidl
Maria Farkas
Andras Nemes
Laszlo Czibula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of DE3165576D1 publication Critical patent/DE3165576D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE8181304833T 1980-10-17 1981-10-16 1,1-disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivatives Expired DE3165576D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU802525A HU183234B (en) 1980-10-17 1980-10-17 Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan

Publications (1)

Publication Number Publication Date
DE3165576D1 true DE3165576D1 (en) 1984-09-20

Family

ID=10959834

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181304833T Expired DE3165576D1 (en) 1980-10-17 1981-10-16 1,1-disubstituted-hexahydro-indolo(2,3-a)quinolizine derivatives and their use in the enantioselective synthesis of optically active 14-oxo-e-homo-eburnane derivatives

Country Status (5)

Country Link
US (1) US4399069A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0050492B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS57145876A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3165576D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU183234B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX150317A (es) * 1978-11-17 1984-04-16 Unilever Nv Mejoras en bolsa cerrada de material en hoja para detergentes en particulas
IT1248881B (it) * 1989-06-21 1995-01-30 Richter Gedeon Vegyeszet Derivati diesteri di ottaidro-indolo/2,3-a/tetraidropiramil/2,3-c/ chinolizina racemici ed otticamente attivi e procedimento per la loro preparazione
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
JP7491514B2 (ja) 2018-03-31 2024-05-28 モレキュラー インターナショナル リサーチ， インコーポレーテッド 予防及び治療に有効な選択的抗がん剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
AU499923B2 (en) * 1975-06-27 1979-05-03 Richter Gedeon Vegyeszeti Gyar N Indoloquinolizine derivatives & their production
GB2010833B (en) * 1977-11-25 1982-04-15 Scras Homoerburnamine preparation
FR2445328A1 (fr) * 1978-07-12 1980-07-25 Richter Gedeon Vegyeszet Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
HU178402B (en) * 1978-08-01 1982-04-28 Richter Gedeon Vegyeszet New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines
HU181495B (en) * 1979-05-31 1983-07-28 Richter Gedeon Vegyeszet Process for producing hydroxy-imino-eburnane derivatives

Also Published As

Publication number Publication date
EP0050492B1 (en) 1984-08-15
US4399069A (en) 1983-08-16
JPH0323551B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-03-29
HU183234B (en) 1984-04-28
EP0050492A1 (en) 1982-04-28
JPS57145876A (en) 1982-09-09

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee