DE3163290D1 - Inert support made of a reticulated copolymer, method of preparing it, and its use in making sustained-release drugs - Google Patents
Inert support made of a reticulated copolymer, method of preparing it, and its use in making sustained-release drugsInfo
- Publication number
- DE3163290D1 DE3163290D1 DE8181401023T DE3163290T DE3163290D1 DE 3163290 D1 DE3163290 D1 DE 3163290D1 DE 8181401023 T DE8181401023 T DE 8181401023T DE 3163290 T DE3163290 T DE 3163290T DE 3163290 D1 DE3163290 D1 DE 3163290D1
- Authority
- DE
- Germany
- Prior art keywords
- methacrylate
- preparing
- weight
- support made
- inert support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001577 copolymer Polymers 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 abstract 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 2
- 125000005250 alkyl acrylate group Chemical group 0.000 abstract 2
- 230000001588 bifunctional effect Effects 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000010526 radical polymerization reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8014529A FR2485370A1 (fr) | 1980-06-30 | 1980-06-30 | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3163290D1 true DE3163290D1 (en) | 1984-05-30 |
Family
ID=9243677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8181401023T Expired DE3163290D1 (en) | 1980-06-30 | 1981-06-25 | Inert support made of a reticulated copolymer, method of preparing it, and its use in making sustained-release drugs |
Country Status (9)
Country | Link |
---|---|
US (2) | US4590068A (de) |
EP (1) | EP0043319B1 (de) |
JP (1) | JPS5740416A (de) |
AT (1) | ATE7200T1 (de) |
CA (1) | CA1214596A (de) |
DE (1) | DE3163290D1 (de) |
ES (2) | ES8300471A1 (de) |
FR (1) | FR2485370A1 (de) |
IE (1) | IE51336B1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2485370A1 (fr) * | 1980-06-30 | 1981-12-31 | Commissariat Energie Atomique | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
US4608249A (en) * | 1982-11-02 | 1986-08-26 | Nitto Electric Industrial Co., Ltd. | Hydrophilic therapeutic material |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
JPS6263508A (ja) * | 1985-09-13 | 1987-03-20 | Kao Corp | 毛髪化粧料 |
US5210166A (en) * | 1985-11-07 | 1993-05-11 | Basf Aktiengesellschaft | Copolymers of ethylene with polyalkylene glycol (meth)acrylates |
US5879716A (en) * | 1985-12-18 | 1999-03-09 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of benzoyl peroxide |
US5145675A (en) * | 1986-03-31 | 1992-09-08 | Advanced Polymer Systems, Inc. | Two step method for preparation of controlled release formulations |
US5955109A (en) * | 1985-12-18 | 1999-09-21 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of retinoic acid |
DE3789956T2 (de) * | 1986-08-15 | 1994-11-10 | Advanced Polymer Systems Inc | Polymere trägerzubereitungen, herstellung und verwendung. |
US4830855A (en) * | 1987-11-13 | 1989-05-16 | Landec Labs, Inc. | Temperature-controlled active agent dispenser |
ZA892859B (en) * | 1988-04-22 | 1989-12-27 | Advanced Polymer Systems Inc | Porous particles in preparations involving immiscible phases |
FR2630326B1 (fr) * | 1988-04-25 | 1990-08-03 | Oreal | Composition cosmetique pour le maquillage contenant des microspheres de poly (beta)-alanine reticulee impregnees d'un alcool polyhydrique inferieur |
DE69014081T2 (de) | 1989-10-31 | 1995-03-30 | Columbia Laboratories, Inc., Miami, Fla. | Mittel zur Feuchthaltung vaginalen Gewebes. |
US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
TW209174B (de) * | 1991-04-19 | 1993-07-11 | Takeda Pharm Industry Co Ltd | |
US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
US5389722A (en) * | 1992-06-05 | 1995-02-14 | Nippon Shokubai Co., Ltd. | Hydrophilic resin and method for production thereof |
US5981719A (en) * | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5516509A (en) * | 1993-03-31 | 1996-05-14 | International Beauty Design, Inc. | Quick-drying nail coating for use over nail polish |
US5407666A (en) * | 1993-04-05 | 1995-04-18 | International Beauty Design, Inc. | Removable, hard, durable, nail coating |
US5788687A (en) * | 1994-02-01 | 1998-08-04 | Caphco, Inc | Compositions and devices for controlled release of active ingredients |
US5554147A (en) * | 1994-02-01 | 1996-09-10 | Caphco, Inc. | Compositions and devices for controlled release of active ingredients |
US5763555A (en) * | 1996-01-22 | 1998-06-09 | Ashland Inc. | Water-borne acrylic emulsion pressure-sensitive adhesive compositions containing multifunctional monomer having improved stability and removability |
AU1745997A (en) * | 1996-01-22 | 1997-08-20 | Ashland Inc. | Water-borne acrylic emulsion pressure-sensitive adhesive compositions containing multifunctional monomer having improved stability and removability |
US20050020613A1 (en) * | 2002-09-20 | 2005-01-27 | Alpharma, Inc. | Sustained release opioid formulations and method of use |
WO2005023181A2 (en) * | 2003-08-22 | 2005-03-17 | Vista Scientific | Polymeric systems for controlled drug therapy |
US20100183688A1 (en) * | 2006-07-24 | 2010-07-22 | Amcol International Corporation | Delivery System and Method of Manufacturing the Same |
WO2011017123A2 (en) | 2009-07-27 | 2011-02-10 | Endologix, Inc. | Stent graft |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3080346A (en) * | 1958-11-15 | 1963-03-05 | Bayer Ag | Sustained-release pharmaceutical preparations |
US3881026A (en) * | 1966-07-26 | 1975-04-29 | Nat Patent Dev Corp | Powdered water-insoluble polymers containing absorbed additives |
US3608063A (en) * | 1969-08-15 | 1971-09-21 | Gilbert S Banker | Molecular drug entrapment process and compositions |
US3857932A (en) * | 1970-09-09 | 1974-12-31 | F Gould | Dry hydrophilic acrylate or methacrylate polymer prolonged release drug implants |
GB1394990A (en) * | 1971-08-12 | 1975-05-21 | Hydrophilics Int Inc | Copolymers and compositions containing copolymers |
US3767790A (en) * | 1972-02-11 | 1973-10-23 | Nat Patent Dev Corp | Microorganisms |
US3966902A (en) * | 1972-05-12 | 1976-06-29 | Airwick Industries, Inc. | Polymer complex carriers for an active ingredient |
US3901967A (en) * | 1973-09-10 | 1975-08-26 | Union Corp | Sustained release of atropine |
FR2250793B1 (de) * | 1973-11-09 | 1978-12-29 | Commissariat Energie Atomique | |
CH602916A5 (de) * | 1975-09-10 | 1978-08-15 | Airwick Ag | |
SE420101B (sv) * | 1978-03-03 | 1981-09-14 | Hoechst Perstorp Ab | Forfarande for framstellning av ett bindemedel for heftlim baserat pa en sampolymer av akrylestrar och eteniskt omettande syror |
CA1125698A (en) * | 1978-03-09 | 1982-06-15 | Masaru Yoshida | Process for preparing a polymer composition |
FR2433949A1 (fr) * | 1978-08-25 | 1980-03-21 | Commissariat Energie Atomique | Substrat hydrophobe apte a liberer une substance chimique |
FR2485370A1 (fr) * | 1980-06-30 | 1981-12-31 | Commissariat Energie Atomique | Support inerte en copolymere reticule, son procede de preparation et son utilisation pour la realisation de medicaments retard |
-
1980
- 1980-06-30 FR FR8014529A patent/FR2485370A1/fr active Granted
-
1981
- 1981-06-22 IE IE1390/81A patent/IE51336B1/en not_active IP Right Cessation
- 1981-06-25 DE DE8181401023T patent/DE3163290D1/de not_active Expired
- 1981-06-25 EP EP81401023A patent/EP0043319B1/de not_active Expired
- 1981-06-25 AT AT81401023T patent/ATE7200T1/de not_active IP Right Cessation
- 1981-06-29 CA CA000380827A patent/CA1214596A/en not_active Expired
- 1981-06-29 ES ES503498A patent/ES8300471A1/es not_active Expired
- 1981-06-30 JP JP56102208A patent/JPS5740416A/ja active Granted
-
1982
- 1982-02-18 ES ES509707A patent/ES8303461A1/es not_active Expired
-
1983
- 1983-08-22 US US06/525,404 patent/US4590068A/en not_active Expired - Lifetime
-
1985
- 1985-08-07 US US06/763,253 patent/US4729904A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE51336B1 (en) | 1986-12-10 |
JPS5740416A (en) | 1982-03-06 |
ES509707A0 (es) | 1983-02-01 |
CA1214596A (en) | 1986-11-25 |
FR2485370B1 (de) | 1984-01-06 |
IE811390L (en) | 1981-12-30 |
FR2485370A1 (fr) | 1981-12-31 |
US4729904A (en) | 1988-03-08 |
ES503498A0 (es) | 1982-11-01 |
US4590068A (en) | 1986-05-20 |
ATE7200T1 (de) | 1984-05-15 |
EP0043319B1 (de) | 1984-04-25 |
ES8300471A1 (es) | 1982-11-01 |
EP0043319A1 (de) | 1982-01-06 |
ES8303461A1 (es) | 1983-02-01 |
JPH0131490B2 (de) | 1989-06-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: ORIS INDUSTRIE S.A., PARIS, FR |
|
8328 | Change in the person/name/address of the agent |
Free format text: GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DIPL.-ING. DR.-ING. STOCKMAIR, W., DIPL.-ING. DR.-ING. AE.E. CAL TECH SCHUMANN, K., DIPL.-PHYS. DR.RER.NAT. JAKOB, P., DIPL.-ING. BEZOLD, G., DIPL.-CHEM. DR.RER.NAT. MEISTER, W., DIPL.-ING. HILGERS, H., DIPL.-ING. MEYER-PLATH, H., DIPL.-ING. DR.-ING. KINKELDEY, U., DIPL.-BIOL. DR.RER.NAT. BOTT-BODENHAUSEN, M., DIPL.-PHYS. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: COMPAGNIE ORIS INDUSTRIE S.A., PARIS, FR |