DE3162614D1 - Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same - Google Patents

Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same

Info

Publication number
DE3162614D1
DE3162614D1 DE8181104100T DE3162614T DE3162614D1 DE 3162614 D1 DE3162614 D1 DE 3162614D1 DE 8181104100 T DE8181104100 T DE 8181104100T DE 3162614 T DE3162614 T DE 3162614T DE 3162614 D1 DE3162614 D1 DE 3162614D1
Authority
DE
Germany
Prior art keywords
same
preparing
pharmaceutical composition
lowering activity
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181104100T
Other languages
English (en)
Inventor
Kazuo Sasahara
Masamitsu Honda
Masuo Koizumi
Yasushi Murakami
Tomohiro Neichi
Hiroshi Nakakimura
Yukifumi Noda
Hiroshi Matsushita
Shun-Ichi Hata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3162614D1 publication Critical patent/DE3162614D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D267/20—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE8181104100T 1980-05-28 1981-05-27 Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same Expired DE3162614D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7017680A JPS56166180A (en) 1980-05-28 1980-05-28 Dibenzoxazepine derivative and its preparation

Publications (1)

Publication Number Publication Date
DE3162614D1 true DE3162614D1 (en) 1984-04-19

Family

ID=13423954

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181104100T Expired DE3162614D1 (en) 1980-05-28 1981-05-27 Dibenzoxazepine derivative, process for preparing the same and pharmaceutical composition comprising the same

Country Status (11)

Country Link
US (1) US4435391A (de)
EP (1) EP0040860B1 (de)
JP (1) JPS56166180A (de)
KR (1) KR850000212B1 (de)
AT (1) ATE6645T1 (de)
CA (1) CA1162189A (de)
DE (1) DE3162614D1 (de)
HU (1) HU183456B (de)
IL (1) IL62894A (de)
MX (1) MX157054A (de)
ZA (1) ZA813385B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240721A3 (de) * 1986-03-12 1991-01-02 Chugai Seiyaku Kabushiki Kaisha Therapeutisches Arzneimittel zur Behandlung von peripheren Zirkulationskrankheiten
CA2200598C (en) * 1994-09-28 1999-12-07 Shuji Jinno Novel anti-oxidative, tricyclic, condensed heterocyclic compound
WO1996033983A1 (fr) * 1995-04-25 1996-10-31 Daiichi Radioisotope Laboratories, Ltd. Derives n-oxyde de dibenzoxazepine et medicament les contenant en tant que principe actif
JP4582366B2 (ja) * 1998-11-30 2010-11-17 東レ・ファインケミカル株式会社 ピロリジン誘導体の製造法
US7550499B2 (en) * 2004-05-12 2009-06-23 Bristol-Myers Squibb Company Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
JP2008527043A (ja) * 2005-01-19 2008-07-24 ブリストル−マイヤーズ スクイブ カンパニー 血栓塞栓障害治療用のｐ２ｙ１受容体阻害剤としての２−フェノキシ−ｎ−（１，３，４−チアジアゾール−２−イル）ピリジン−３−アミン誘導体および関連化合物
EP1899299B1 (de) * 2005-06-27 2010-10-20 Bristol-Myers Squibb Company C-verknüpfte zyklische antagonisten des p2y1-rezeptors mit eignung bei der behandlung thrombotischer leiden
US7728008B2 (en) * 2005-06-27 2010-06-01 Bristol-Myers Squibb Company N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
US7714002B2 (en) * 2005-06-27 2010-05-11 Bristol-Myers Squibb Company Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
ATE502924T1 (de) * 2005-06-27 2011-04-15 Bristol Myers Squibb Co Lineare harnstoffmimetika-antagonisten des p2y1- rezeptors zur behandlung von thromboseleiden
US20080090805A1 (en) * 2005-10-17 2008-04-17 Acadia Pharmaceuticals Inc. Cb-1 modulating compounds and their use
EP1937677A1 (de) * 2005-10-17 2008-07-02 Arcadia Pharmaceuticals Inc. Cb-1-modulierende verbindungen und deren anwendung
US7960569B2 (en) * 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
US8461145B2 (en) 2007-12-05 2013-06-11 Janssen Pharmaceutica Nv Dibenzoazepine and dibenzooxazepine TRPA1 agonists
WO2019173761A1 (en) * 2018-03-09 2019-09-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services C-abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH473141A (de) 1965-12-30 1969-05-31 Wander Ag Dr A Verfahren zur Herstellung 11-aminoalkylierter Dibenz(b,f)-1,4-oxazepine und Dibenzo(b,f)-1,4-thiazepine
US3646009A (en) 1967-03-15 1972-02-29 Boehringer & Soehne Gmbh Anti-diabetically active sulfonyl-semicarbazides
US3458516A (en) 1968-02-16 1969-07-29 American Cyanamid Co 11-(piperazinyl)dibenz(b,f)(1,4)oxazepines and analogous thiazepines
DE2014223A1 (de) 1969-03-28 1970-10-01 Sumitomo Chemical Company Ltd., Osaka (Japan) Benzoxazepin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
JPS5576869A (en) 1978-12-06 1980-06-10 Chugai Pharmaceut Co Ltd Dibenzoxazepine derivative and its preparation

Also Published As

Publication number Publication date
MX157054A (es) 1988-10-24
CA1162189A (en) 1984-02-14
KR830006249A (ko) 1983-09-20
US4435391A (en) 1984-03-06
ZA813385B (en) 1982-06-30
KR850000212B1 (ko) 1985-03-06
IL62894A (en) 1984-10-31
JPS56166180A (en) 1981-12-21
IL62894A0 (en) 1981-07-31
ATE6645T1 (de) 1984-03-15
JPH0223550B2 (de) 1990-05-24
EP0040860B1 (de) 1984-03-14
HU183456B (en) 1984-05-28
EP0040860A1 (de) 1981-12-02

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee