DE3065088D1 - Novel bis- and mono-quaternary ammonium derivatives of 2-beta, 16-beta-dipiperidino-5-alpha-androstanes, processes for their preparation and pharmaceutical preparations - Google Patents

Novel bis- and mono-quaternary ammonium derivatives of 2-beta, 16-beta-dipiperidino-5-alpha-androstanes, processes for their preparation and pharmaceutical preparations

Info

Publication number
DE3065088D1
DE3065088D1 DE8080201186T DE3065088T DE3065088D1 DE 3065088 D1 DE3065088 D1 DE 3065088D1 DE 8080201186 T DE8080201186 T DE 8080201186T DE 3065088 T DE3065088 T DE 3065088T DE 3065088 D1 DE3065088 D1 DE 3065088D1
Authority
DE
Germany
Prior art keywords
beta
dipiperidino
androstanes
mono
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080201186T
Other languages
German (de)
English (en)
Inventor
Jan Dr Kelder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of DE3065088D1 publication Critical patent/DE3065088D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE8080201186T 1979-12-12 1980-12-09 Novel bis- and mono-quaternary ammonium derivatives of 2-beta, 16-beta-dipiperidino-5-alpha-androstanes, processes for their preparation and pharmaceutical preparations Expired DE3065088D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7942883 1979-12-12

Publications (1)

Publication Number Publication Date
DE3065088D1 true DE3065088D1 (en) 1983-11-03

Family

ID=10509800

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080201186T Expired DE3065088D1 (en) 1979-12-12 1980-12-09 Novel bis- and mono-quaternary ammonium derivatives of 2-beta, 16-beta-dipiperidino-5-alpha-androstanes, processes for their preparation and pharmaceutical preparations

Country Status (12)

Country Link
US (1) US4348390A (sv)
EP (1) EP0032261B1 (sv)
JP (1) JPH026360B2 (sv)
AU (1) AU534992B2 (sv)
CA (1) CA1153366A (sv)
DE (1) DE3065088D1 (sv)
DK (1) DK158741C (sv)
ES (1) ES8204443A1 (sv)
FI (1) FI66394C (sv)
HU (1) HU185865B (sv)
IE (1) IE50675B1 (sv)
WO (1) WO1981001710A1 (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53463B1 (en) * 1981-06-15 1988-11-23 Akzo Nv Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
US4726275A (en) * 1983-05-10 1988-02-23 Synthaxe Limited Electronic musical instrument
US5418226A (en) * 1992-04-22 1995-05-23 Akzo N.V. Monoquaternary 2,16-bispiperidinylandrostane derivatives
US5926516A (en) * 1995-05-24 1999-07-20 Siemens Aktiengesellschaft Absorption structure for absorbing neutrons and method for producing an absorption structure
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
US5990124A (en) * 1997-10-24 1999-11-23 Gyermek; Laszlo Neuromuscular relaxants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
GB1454749A (en) * 1972-11-29 1976-11-03 Akzo Nv 2beta, 16beta-diamino-androstanes and their preparation
HU172522B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej
ATE921T1 (de) * 1978-09-05 1982-05-15 Akzo N.V. Saeureadditionssalze von 2-beta, 16-beta-bis-piperidino-an drostan-16-beta-monoquaternaeren ammoniumderivaten und diese enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
US4348390A (en) 1982-09-07
FI66394C (fi) 1984-10-10
ES497724A0 (es) 1982-05-01
JPH026360B2 (sv) 1990-02-08
WO1981001710A1 (en) 1981-06-25
IE50675B1 (en) 1986-06-11
EP0032261B1 (en) 1983-09-28
FI811857L (fi) 1981-06-15
HU185865B (en) 1985-04-28
ES8204443A1 (es) 1982-05-01
DK158741B (da) 1990-07-09
JPS56501761A (sv) 1981-12-03
DK260881A (da) 1981-06-25
IE802566L (en) 1981-06-12
DK158741C (da) 1990-11-26
CA1153366A (en) 1983-09-06
AU6640581A (en) 1981-07-06
FI66394B (fi) 1984-06-29
EP0032261A1 (en) 1981-07-22
AU534992B2 (en) 1984-02-23

Similar Documents

Publication Publication Date Title
DE2861688D1 (en) Quinazoline derivatives, process for their preparation, pharmaceutical preparations and their preparation
IL60510A (en) Derivatives of n-(mercaptoalkylcarbonyl)glycine,processes for their preparation and pharmaceutical compositions containing them
DE3067252D1 (en) Cyclopeptides and pharmaceutical preparations thereof, process for their preparation and their use
IL59679A (en) Derivatives of glycinamide,their preparation and pharmaceutical compositions containing them
DE3062586D1 (en) 2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same
IL59425A0 (en) N-substituted aziridine-2-carboxylic acid derivatives,processes for preparation thereof and pharmaceutical compositins containing the same
DE3067258D1 (en) Substituted 3-amino-sydnonimines, process for their synthesis and pharmaceutical preparations containing them
DE2964249D1 (en) Isoquinoline derivatives, process for their preparation and pharmaceutical preparations containing them
DE3062884D1 (en) Spiro-hydantoin derivatives, process for their preparation and pharmaceutical compositions thereof
GB2043644B (en) 3-phosphonocephalosporanic acid derivatives process for preparation thereof and pharmaceutical composition comprising the same
DE3060345D1 (en) Fluortriazine derivatives, process for the preparation of fluortriazin-derivatives and reactive dyes and their application
DE3261364D1 (en) Novel mono - and bisquaternary ammonium derivatives of 2-beta, 16-beta-diamino-5-alpha-androstane derivatives and pharmaceutical preparations containing same
DE3065088D1 (en) Novel bis- and mono-quaternary ammonium derivatives of 2-beta, 16-beta-dipiperidino-5-alpha-androstanes, processes for their preparation and pharmaceutical preparations
IL60325A0 (en) Novel quinazoline derivatives and pharmaceutical preparations containing them
ZA803535B (en) Novel quinazoline derivatives and pharmaceutical preparations
DE3062017D1 (en) Phenyliminothiazoline derivatives, their preparation and intermediates therefor, pharmaceutical preparations containing them and their production
EP0081478A3 (en) Novel halophenyl-pyridyl-allylamine derivatives, processes and intermediates as well as pharmaceutical preparations thereof
DE2960675D1 (en) Isoquinolines, process for their preparation, and pharmaceutical preparations containing them
DE3063335D1 (en) Tetrahydroquinoline derivatives, processes for their production, their use and pharmaceutical preparations containing them
DE3060079D1 (en) Spiro-quinolylhydantoins, process for their preparation and pharmaceutical compositions thereof
AU6546780A (en) N-substituted amino acids, their production, and pharmaceutical preparations containing them
DE2961524D1 (en) Glycofuranosyl-nitrosourea derivatives, process for their manufacture and their pharmaceutical preparations
DE3071750D1 (en) Nasal preparations, process for making same and their use
DE3061160D1 (en) 15-methanesulfonamidoprostaglandin derivatives, pharmaceutical compositions thereof and process therefor
DE3264595D1 (en) N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee