DE3026898A1 - Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums - Google Patents

Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums

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Publication number
DE3026898A1
DE3026898A1 DE19803026898 DE3026898A DE3026898A1 DE 3026898 A1 DE3026898 A1 DE 3026898A1 DE 19803026898 DE19803026898 DE 19803026898 DE 3026898 A DE3026898 A DE 3026898A DE 3026898 A1 DE3026898 A1 DE 3026898A1
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Germany
Prior art keywords
capillary
test
filled
micro
blood
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Ceased
Application number
DE19803026898
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German (de)
Inventor
Günter 4430 Steinfurt Keul
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Individual
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Individual
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Priority to DE19803026898 priority Critical patent/DE3026898A1/en
Publication of DE3026898A1 publication Critical patent/DE3026898A1/en
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

A microcapillary for a one-off test, for use in clinical laboratories for blood or urine checks, has been filled by capillary action with analytical reagents, biochemicals, control serums, standard or calibration substances or coated. A sample of blood or urine can thus be checked by direct reaction; based on a colour scale or comparative Table in qualitative, semiquantative or quantitative fashion. This saves the various pipette operations required in the conventional procedure of mixing a sample in turn with various reagents and to check the reaction in a dish. The tests are thus simplified and free from errors.

Description

Titel: Einmal-Micro-Kapillar-Test Patentansprüche: 1. 0 Einmal-Micro-Kapillaren, oder Gegenstände, die auf der Kapillarwirkung beruhen, die mit analytischen Substanzen, Biochemica, Kontrollseren, Standards und Eichsubstanzen oder anderen Diagnostica gefüllt oder beschichtet sind und dadurch keinen zusätzlichen Arbeitsgang durch nochmaliges Pipettieren erforderlich machten. Nach Abnahme der Probe kann dann die so erfolgte direkte Reaktion an Hand einer Farbskala oder Vergleichstafel qualitativ, halbquantitativ bzw. quantitativ ausgewertet werden. Eine weitere qualitative, halbquantitative oder quantitative Auswertungsmögl ichkeit ergibt sich durch die photometrische Messung.Title: Disposable Micro Capillary Test Claims: 1. 0 Disposable Micro Capillaries, or objects that are based on the capillary effect, which with analytical substances, Biochemica, control sera, standards and calibration substances or other diagnostics filled or coated and therefore no additional work step made repeated pipetting necessary. After the sample has been taken, the so there was a qualitative direct reaction on the basis of a color scale or comparison chart, be evaluated semi-quantitatively or quantitatively. Another qualitative, semi-quantitative or quantitative evaluation option results from the photometric measurement.

Kritik am Stand der Technik: 2.) Bisher untersuchte man Proben mittels herkömmlicher Testverfahren, indem man im klinischen Laboratorium dem Patienten Blut oder Urin entnahm und diese Probe nacheinander mit verschiedenen Reagenzien mischte und anschließend die Messung in einer Küvette durchführte. Auf diese Art und Weise entstanden natürlich viele Pipettierfehler oder Konzentrationsfehler. Außerdem entstand noch ein zeitlicher Fehler, da eine gewisse Zeit vergeht, bevor das Blut oder der Urin mit den Reaktionspartnern zusammentrifft. Außerdem tritt bei manchen Bestimmungen durch Gerinnungshemmer eine Ergebnisverfälschung ein.Criticism of the state of the art: 2.) So far, samples have been examined using conventional testing method by looking at the patient in the clinical laboratory Blood or urine was drawn and this sample was taken one at a time with various reagents mixed and then carried out the measurement in a cuvette. In this manner And of course there were many pipetting errors or concentration errors. There was also a timing error because a certain amount of time passed before the blood or urine meets the reactants. Also occurs for some determinations a result falsified by anticoagulants.

Ein weiterer Nachteil besteht bei Teststreifen darin, daß man bei Teststreifen im "Eintauchverfahren" eine viel zu große Menge Harn, Serum, Blut oder Plasma benötigte und durch die nicht konstante Probemenge beim Teststreifen, die im photometrischen Reflektionsverfahren ausgewertet wurden, ebenfalls eine Verfälschung eintreten konnte. Another disadvantage of test strips is that you have to Test strips in the "immersion procedure" a much too large amount of urine, serum, blood or Plasma required and due to the inconsistent sample amount in the test strip, the were evaluated in the photometric reflection method, also a falsification could enter.

Aufgabe: 3.) Der Erfindung liegt die Aufgabe zugrunde, die im bisherigen Analysengang unter Punkt 2.) (Kritik) geschilderten Mängel zu beseitigen und eine leicht zu handhabende und bessere Alternative zu den bisherigen Analysen-Verfahren, -Stoffen und -Geräten zu bieten.Task: 3.) The invention is based on the task in the previous Analysis process under point 2.) (criticism) to eliminate the deficiencies and a easy-to-use and better alternative to the previous analysis methods, Fabrics and equipment.

Lösung: 4) Der unter Punkt 1.) (Patentanspruch) geschilderte Einmal-Micro-Kapillar-Test, welcher mit analytischen 0Substanzen, Biochemica, Kontrollseren, Standards und Eichsubstanzen oder anderen Diagnostica gefüllt oder beschichtet ist.Solution: 4) The single-use micro-capillary test described under point 1.) (patent claim), which with analytical substances, biochemicals, control sera, standards and calibration substances or other diagnostics is filled or coated.

Claims (1)

Vorteile: 5.) Bei einem solchen Einmal-Micro-Kapillar-Test trifft die Probe sofort bei der Entnahme unter konstantem Volumen auf das Reaktionsmedium bzw. -Medien, welche (r) außerdem nur geringe Mengen an Proben benötigt (en), (z.B. sehr wichtig bei der Blutentnahme von Kleinkindern). Durch den Einmal-Micro-Kapillar-Test tritt eine erhebliche Vereinfachung und bessere Reproduzierbarkeit ein.Advantages: 5.) In such a single-use micro-capillary test hits Immediately upon removal of the sample under constant volume on the reaction medium or media that also only require small amounts of samples (e.g. very important when taking blood from small children). With the disposable micro-capillary test there is a considerable simplification and better reproducibility.
DE19803026898 1980-07-16 1980-07-16 Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums Ceased DE3026898A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19803026898 DE3026898A1 (en) 1980-07-16 1980-07-16 Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803026898 DE3026898A1 (en) 1980-07-16 1980-07-16 Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums

Publications (1)

Publication Number Publication Date
DE3026898A1 true DE3026898A1 (en) 1982-02-04

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DE19803026898 Ceased DE3026898A1 (en) 1980-07-16 1980-07-16 Micro-capillary for one-off test - filled by capillary action with analytical reagents or control serums

Country Status (1)

Country Link
DE (1) DE3026898A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226407A1 (en) * 1982-07-15 1984-01-19 Volker Dr. 6900 Heidelberg Daniel Microanalysis capillary system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226407A1 (en) * 1982-07-15 1984-01-19 Volker Dr. 6900 Heidelberg Daniel Microanalysis capillary system

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