DE29923907U1 - Miniaturized slide for carrying out a large number of test series in the submicroliter range - Google Patents

Miniaturized slide for carrying out a large number of test series in the submicroliter range

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Publication number
DE29923907U1
DE29923907U1 DE29923907U DE29923907U DE29923907U1 DE 29923907 U1 DE29923907 U1 DE 29923907U1 DE 29923907 U DE29923907 U DE 29923907U DE 29923907 U DE29923907 U DE 29923907U DE 29923907 U1 DE29923907 U1 DE 29923907U1
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Germany
Prior art keywords
miniaturized
areas
slide
slide according
sample receiving
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE29923907U
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German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
QUANTIFOIL MICRO TOOLS GmbH
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QUANTIFOIL MICRO TOOLS GmbH
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Application filed by QUANTIFOIL MICRO TOOLS GmbH filed Critical QUANTIFOIL MICRO TOOLS GmbH
Priority to DE29923907U priority Critical patent/DE29923907U1/en
Publication of DE29923907U1 publication Critical patent/DE29923907U1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00617—Delimitation of the attachment areas by chemical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00617—Delimitation of the attachment areas by chemical means
    • B01J2219/00619—Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/0063—Other, e.g. van der Waals forces, hydrogen bonding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B01J2219/00662—Two-dimensional arrays within two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microscoopes, Condenser (AREA)
  • Sampling And Sample Adjustment (AREA)

Description

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßt The description text was not recorded electronically  

Der Beschreibungstext wurde nicht elektronisch erfaßtThe description text was not recorded electronically

Claims (14)

1. Miniaturisierter Objektträger zur Durchführung einer Vielzahl von Testreihen im Submikroliterbereich, bestehend aus eiern Träger (t) mit wenigstens einer Zeile (z1) von in Gruppen (g1. . .g8) zusammengefaßter einzelner Probenaufnahmebereiche (a), denen zu den sie jeweils umfassenden Objektträgerbereichen ein entgegengesetztes Benetzungsverhalten gegeben ist, wobei jeweils in einer Gruppe (g1, g2 bis g8) gleichplazierte Probenaufnahmebereiche (a11, a21 bis a81) zueinander Jeweils identisch beabstandet sind und das Maß (d) dieser Beabstandung dem Rastermaß (d) des Abstands von Kavitäten (k1, k2 bis k8) einer Mikrotiterplatte (in) und/oder dem Abstand benachbarter einzelner Probenaufgabemittel (p1, p2 bis p8) einer Mikropipettiereinrichtung (p) entsprechend vorgebbar festgelegt ist.1. Miniaturized slide for carrying out a variety of Test series in the submicroliter range, consisting of egg carrier (t) with at least one line (z1) of in groups (g1 ... G8) summarized individual sample receiving areas (a) to which the slide areas they encompass opposite wetting behavior is given, in each case in a group (g1, g2 to g8) placed in the same area (a11, a21 to a81) are each spaced identically from one another and the dimension (d) of this spacing the grid dimension (d) of the distance of cavities (k1, k2 to k8) of a microtiter plate (in) and / or the Distance between adjacent individual sample application means (p1, p2 to p8) a micropipetting device (p) can be predetermined accordingly is. 2. Miniaturisierter Objektträger nach Anspruch 1, dadurch gekennzeichnet, daß das Produkt aus vorgesehenen Zeilen (z1. . .z12) und Arealen (A1. . .A8) zusammengehöriger einzelner Probenaufnahmebereiche derart festgelegt ist, daß es der Anzahl von Kavitäten (k1. . .k96) einer vorgelegten Mikrotiterplatte (m) entspricht.2. Miniaturized slide according to claim 1, characterized characterized that the product from the intended lines (z1. .z12) and areas (A1 ... A8) of related individual Sample receiving areas is set to be the number of Cavities (k1 ... K96) corresponds to a microtiter plate (m). 3. Miniaturisierter Objektträger nach Anspruch 2, dadurch gekennzeichnet, daß pro Areal (A1. . .A8) soviele einzelne Probenaufnahmebereiche (a) vorgesehen sind, daß sie der Anzahl der Kavitäten (k1. . .k96) der vorgelegten Mikrotiterplatte (in) entsprechen.3. Miniaturized slide according to claim 2, characterized characterized in that so many individual areas (A1 ... A8) Sample receiving areas (a) are provided that they are the number of Cavities (k1 ... K96) correspond to the microtiter plate (in). 4. Miniaturisierter Objektträger nach Ansprach 1, dadurch gekennzeichnet, daß das Produkt aus vorgesehenen Zeilen (z1... z12) und Arealen (A1. . .A8) zusammengehöriger einzelner Probenaufnahmebereiche (a) derart festgelegt ist, daß es der Anzahl durch eine Mikropipettiereinrichtung (p) zu übertragenden Proben entspricht. 4. Miniaturized slide according to speech 1, thereby characterized that the product from the specified lines (z1 ... z12) and areas (A1 ... A8) of related individual Sample receiving areas (a) is set so that it is the number samples to be transferred by a micropipetting device (p) corresponds.   5. Miniaturisierter Objektträger nach Anspruch 4, dadurch gekennzeichnet, daß pro Areal (A1. . .A8) soviele einzelne Probenaufnahmebereiche vorgesehen sind, daß sie der Anzahl durch eine Mikropipettiereinrichtung zu übertragenden Proben entsprechen.5. Miniaturized slide according to claim 4, characterized characterized in that so many individual areas (A1 ... A8) Sampling areas are provided so that they can count through correspond to a micropipetting device to be transferred samples. 6. Miniaturisierter Objektträger nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, daß den einzelnen Probenaufnahmebereichen (a) Durchmesser in der Größenordnung von 10. . .1000 µm gegeben sind.6. Miniaturized slide according to one of the preceding claims, characterized in that the individual sample receiving areas (a) Diameter on the order of 10. .1000 µm given are. 7. Miniaturisierter Objektträger nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, daß die einzelnen Probenaufnahmebereiche durch chemische Modifikation mit Bindungsflächen für zu testende Probensubstanzen versehen sind.7. Miniaturized slide according to one of the preceding claims, characterized in that the individual sample receiving areas through chemical modification with binding surfaces for those to be tested Sample substances are provided. 8. Miniaturisierter Objektträger nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, daß den einzelnen Probenaufnahmebereichen eine hydrophile Oberflächeneigenschaft aufgeprägt ist, wohingegen den sie umfassenden Objektträgerbereichen eine hydrophobe Oberflächeneigenschaft aufgeprägt ist.8. Miniaturized slide according to one of the preceding claims, characterized in that the individual sample receiving areas a hydrophilic surface property is imprinted, whereas the slide areas surrounding them a hydrophobic Surface property is imprinted. 9. Miniaturisierter Objektträger nach Anspruch 1 und 8, dadurch gekennzeichnet, daß den hydrophoben Objektträgerbereichen eine zusätzliche dreidimensionale Mikrostruktur aufgeprägt ist.9. Miniaturized slide according to claim 1 and 8, characterized characterized in that the hydrophobic slide areas a additional three-dimensional microstructure is embossed. 10. Miniaturisierter Objektträger nach Anspruch 9, dadurch gekennzeichnet, daß die Mikrostrukturen mit Aspektverhältnissen im Mikrometerbereich von 1/1 bis 5/1 ausgebildet sind.10. Miniaturized slide according to claim 9, characterized characterized in that the microstructures with aspect ratios in the Micrometer range from 1/1 to 5/1 are formed. 11. Miniaturisierter Objektträger nach Anspruch 1, dadurch gekennzeichnet, daß der Objektträger (t) optisch transparent ist.11. Miniaturized slide according to claim 1, characterized characterized in that the slide (t) is optically transparent. 12. Miniaturisierter Objektträger nach Anspruch 1, dadurch gekennzeichnet, daß der Objektträger (t) in der Dimensionierung entsprechend den In der Mikroskopie üblichen Glasobjektträgern ausgebildet ist. 12. Miniaturized slide according to claim 1, characterized characterized in that the slide (t) in the dimensioning corresponding to the glass slides usual in microscopy is trained.   3. Miniaturisierter Objektträger nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, daß der Objektträger (t) entlang zwischen den Arealen (A1. . .An) vorgebbaren Linien (L) vereinzelbar ist.3. Miniaturized slide according to one of the preceding claims, characterized in that the slide (t) along between lines (L) which can be specified in the areas (A1... An) can be separated. 14. Miniaturisierter Objektträger nach Anspruch 13, dadurch gekennzeichnet, daß entlang der vorgebbaren Linien Sollbruchstellen im Objektträger (t) vorgesehen sind.14. Miniaturized slide according to claim 13, characterized characterized that along the predetermined lines Predetermined breaking points are provided in the slide (t).
DE29923907U 1999-12-01 1999-12-01 Miniaturized slide for carrying out a large number of test series in the submicroliter range Expired - Lifetime DE29923907U1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE29923907U DE29923907U1 (en) 1999-12-01 1999-12-01 Miniaturized slide for carrying out a large number of test series in the submicroliter range

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19958839 1999-12-01
DE29923907U DE29923907U1 (en) 1999-12-01 1999-12-01 Miniaturized slide for carrying out a large number of test series in the submicroliter range

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DE29923907U1 true DE29923907U1 (en) 2001-07-26

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10241409A1 (en) * 2002-09-06 2004-03-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Microarray carrier, useful for detecting protein or DNA, comprises substrate of hydrophobic polymer with functionalized hydrophilic regions containing silanol groups
DE10242066A1 (en) * 2002-09-11 2004-03-25 Ngoli, Dominique, Dr. Culturing cells without stressing them, for microscopy to e.g. assess test substances, cultures cell layer on carrier, subsequently transferring growth over to second carrier
WO2005098031A1 (en) * 2004-04-06 2005-10-20 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Liquid-based hybridization assay
DE102006014000A1 (en) * 2006-03-27 2007-10-25 Advalytix Ag Method for characterizing a mixed sample
CN103454414A (en) * 2013-09-25 2013-12-18 河南科技大学 96-hole reaction plate
WO2013189818A1 (en) * 2012-06-18 2013-12-27 Siemens Aktiengesellschaft Assembly and method for analyzing nucleic acid sequences
DE102016104808A1 (en) * 2016-03-15 2017-09-21 Als Automated Lab Solutions Gmbh Device for insertion into an imaging system
AT524623A1 (en) * 2020-11-11 2022-05-15 Hvd Biotech Vertriebsgesellschaft M B H Solid support comprising a set of protein arrays

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10241409A1 (en) * 2002-09-06 2004-03-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Microarray carrier, useful for detecting protein or DNA, comprises substrate of hydrophobic polymer with functionalized hydrophilic regions containing silanol groups
DE10242066A1 (en) * 2002-09-11 2004-03-25 Ngoli, Dominique, Dr. Culturing cells without stressing them, for microscopy to e.g. assess test substances, cultures cell layer on carrier, subsequently transferring growth over to second carrier
DE10242066B4 (en) * 2002-09-11 2005-03-17 Cytopharm Gmbh Process for the treatment of cell cultures
WO2005098031A1 (en) * 2004-04-06 2005-10-20 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Liquid-based hybridization assay
DE102006014000A1 (en) * 2006-03-27 2007-10-25 Advalytix Ag Method for characterizing a mixed sample
DE102006014000B4 (en) * 2006-03-27 2009-08-06 Advalytix Ag Method for characterizing a mixed sample
US9777323B2 (en) 2012-06-18 2017-10-03 Siemens Aktiengesellschaft Assembly and method for analyzing nucleic acid sequences by way of so-called sequencing-by-synthesis
WO2013189818A1 (en) * 2012-06-18 2013-12-27 Siemens Aktiengesellschaft Assembly and method for analyzing nucleic acid sequences
CN103454414A (en) * 2013-09-25 2013-12-18 河南科技大学 96-hole reaction plate
CN103454414B (en) * 2013-09-25 2015-04-01 河南科技大学 96-hole reaction plate
DE102016104808A1 (en) * 2016-03-15 2017-09-21 Als Automated Lab Solutions Gmbh Device for insertion into an imaging system
US11266991B2 (en) 2016-03-15 2022-03-08 Als Automated Lab Solutions Gmbh Device for insertion into an imaging system
AT524623A1 (en) * 2020-11-11 2022-05-15 Hvd Biotech Vertriebsgesellschaft M B H Solid support comprising a set of protein arrays
WO2022099343A1 (en) * 2020-11-11 2022-05-19 Hvd Biotech Vertriebsgesellschaft M.B.H. Solid support comprising a set of protein arrays
AT524623B1 (en) * 2020-11-11 2023-02-15 Hvd Biotech Vertriebsgesellschaft M B H Solid support comprising a set of protein arrays

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R150 Term of protection extended to 6 years

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