DE2967535D1 - Xanthinoxydase inhibitors and utilization of benzotriazine derivatives - Google Patents
Xanthinoxydase inhibitors and utilization of benzotriazine derivativesInfo
- Publication number
- DE2967535D1 DE2967535D1 DE7979104432T DE2967535T DE2967535D1 DE 2967535 D1 DE2967535 D1 DE 2967535D1 DE 7979104432 T DE7979104432 T DE 7979104432T DE 2967535 T DE2967535 T DE 2967535T DE 2967535 D1 DE2967535 D1 DE 2967535D1
- Authority
- DE
- Germany
- Prior art keywords
- xanthinoxydase
- inhibitors
- utilization
- xanthine oxidase
- benzotriazine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OWQPOVKKUWUEKE-UHFFFAOYSA-N 1,2,3-benzotriazine Chemical class N1=NN=CC2=CC=CC=C21 OWQPOVKKUWUEKE-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 2
- 229940123769 Xanthine oxidase inhibitor Drugs 0.000 abstract 2
- 239000003064 xanthine oxidase inhibitor Substances 0.000 abstract 2
- LLMGYOJUHDRDFJ-UHFFFAOYSA-N 5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione;dihydrate Chemical compound O.O.CC1=CC=C2N=C(N(C)C)N3C(=O)C(CCC)C(=O)N3C2=C1 LLMGYOJUHDRDFJ-UHFFFAOYSA-N 0.000 abstract 1
- 108010093894 Xanthine oxidase Proteins 0.000 abstract 1
- 102100033220 Xanthine oxidase Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP79104432A EP0028660B1 (de) | 1979-11-10 | 1979-11-10 | Xanthinoxydasehemmer und Verwendung von Benztriazinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2967535D1 true DE2967535D1 (en) | 1985-11-28 |
Family
ID=8186233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE7979104432T Expired DE2967535D1 (en) | 1979-11-10 | 1979-11-10 | Xanthinoxydase inhibitors and utilization of benzotriazine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4305942A (enExample) |
| EP (1) | EP0028660B1 (enExample) |
| JP (1) | JPS5695116A (enExample) |
| AT (1) | ATE16150T1 (enExample) |
| DE (1) | DE2967535D1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190072B (en) * | 1983-03-11 | 1986-08-28 | Biogal Gyogyszergyar,Hu | Process for production of medical preparatives with sinergetic influence |
| GB2155329A (en) * | 1984-03-08 | 1985-09-25 | Kim Drummond Rainsford | A pharmaceutical formulation containing azapropazone |
| US4668676A (en) * | 1985-12-06 | 1987-05-26 | E.I. Du Pont De Nemours And Company | Azapropazone prevention of post-ischemic tissue damage |
| JPS62138431A (ja) * | 1985-12-06 | 1987-06-22 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | 虚血後組織損傷のアザプロパゾンによる防止 |
| AUPM835394A0 (en) | 1994-09-23 | 1994-10-13 | King, Michael G. Dr. | Method for controlling or eliminating the need to smoke tobacco, and for treating ailments which may lead to the said need |
| US5965625A (en) * | 1997-03-21 | 1999-10-12 | King; Michael Glenn | Compositions and methods for the control of smoking |
| EP2165705A1 (en) | 2008-09-18 | 2010-03-24 | Centre National de la Recherche Scientifique (CNRS) | Use of a compound capable of reducing the uric acid level for the prevention and/or the treatment of lung inflammation and fibrosis |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH487171A (de) * | 1963-10-22 | 1970-03-15 | Siegfried Ag | Verfahren zur Herstellung therapeutisch wirksamer 1,2-Dihydro-1,2,4-benztriazine |
-
1979
- 1979-11-10 DE DE7979104432T patent/DE2967535D1/de not_active Expired
- 1979-11-10 AT AT79104432T patent/ATE16150T1/de not_active IP Right Cessation
- 1979-11-10 EP EP79104432A patent/EP0028660B1/de not_active Expired
-
1980
- 1980-10-28 US US06/201,500 patent/US4305942A/en not_active Expired - Lifetime
- 1980-11-10 JP JP15712780A patent/JPS5695116A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0144685B2 (enExample) | 1989-09-29 |
| EP0028660B1 (de) | 1985-10-23 |
| US4305942A (en) | 1981-12-15 |
| JPS5695116A (en) | 1981-08-01 |
| EP0028660A1 (de) | 1981-05-20 |
| ATE16150T1 (de) | 1985-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |