DE2965841D1 - 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof - Google Patents

2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof

Info

Publication number
DE2965841D1
DE2965841D1 DE7979900876T DE2965841T DE2965841D1 DE 2965841 D1 DE2965841 D1 DE 2965841D1 DE 7979900876 T DE7979900876 T DE 7979900876T DE 2965841 T DE2965841 T DE 2965841T DE 2965841 D1 DE2965841 D1 DE 2965841D1
Authority
DE
Germany
Prior art keywords
dopaminimino
tetrahydronaphthalene
dihydroxy
alpha
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979900876T
Other languages
German (de)
English (en)
Inventor
David Michael Stout
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
American Hospital Supply Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Hospital Supply Corp filed Critical American Hospital Supply Corp
Application granted granted Critical
Publication of DE2965841D1 publication Critical patent/DE2965841D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE7979900876T 1978-07-14 1979-06-18 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof Expired DE2965841D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92476378A 1978-07-14 1978-07-14
PCT/US1979/000434 WO1980000251A1 (en) 1978-07-14 1979-06-18 Derivatives of 2-amino-6,7-dihydroxytetrahydronaphthalene(adtn)

Publications (1)

Publication Number Publication Date
DE2965841D1 true DE2965841D1 (en) 1983-08-18

Family

ID=25450688

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979900876T Expired DE2965841D1 (en) 1978-07-14 1979-06-18 2-alpha-methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, its salts, and a process for preparation thereof

Country Status (4)

Country Link
EP (1) EP0016148B1 (cg-RX-API-DMAC7.html)
JP (1) JPS639500B2 (cg-RX-API-DMAC7.html)
DE (1) DE2965841D1 (cg-RX-API-DMAC7.html)
WO (1) WO1980000251A1 (cg-RX-API-DMAC7.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
FI832108A7 (fi) * 1981-05-11 1983-06-10 Arvidsson Folke Lars Erik Terapeuttisesti käyttökelpoiset tetraliinijohdannaiset III, menetelmät tällaisten yhdisteiden valmistavalmistamiseksi ja farmaseuttiset valm isteet tällaisille yhdisteille.
IT1241988B (it) * 1990-06-15 1994-02-02 Sigma Tau Ind Farmaceuti 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE745314C (de) * 1941-03-15 1944-11-27 Troponwerke Dinklage & Co Verfahren zur Herstellung von analgetisch wirkenden 1-Oxyphenyl-3-aminoalkylverbindungen
US3135797A (en) * 1958-04-15 1964-06-02 Colgate Palmolive Co Aromatic amino antispasmodic compounds
US3579582A (en) * 1967-02-16 1971-05-18 Universal Oil Prod Co Hydroxy and/or hydrocarbyloxy and amino substituted tetrahydronaphthalenes
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
JPS5826332B2 (ja) * 1974-04-25 1983-06-02 武田薬品工業株式会社 テトラロ−ルカゴウブツ ノ セイゾウホウ
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0016148A1 (en) 1980-10-01
EP0016148B1 (en) 1983-07-13
JPS639500B2 (cg-RX-API-DMAC7.html) 1988-02-29
EP0016148A4 (en) 1980-10-13
JPS55500419A (cg-RX-API-DMAC7.html) 1980-07-10
WO1980000251A1 (en) 1980-02-21

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: THE DU PONT MERCK PHARMACEUTICAL CO., WILMINGTON,

8328 Change in the person/name/address of the agent

Free format text: ABITZ, W., DIPL.-ING.DR.-ING. MORF, D., DR. GRITSCHNEDER, M., DIPL.-PHYS. FRHR. VON WITTGENSTEIN, A., DIPL.-CHEM. DR.PHIL.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee