DE2962822D1 - New anthracycline derivatives and process for preparing the same - Google Patents

New anthracycline derivatives and process for preparing the same

Info

Publication number
DE2962822D1
DE2962822D1 DE7979103393T DE2962822T DE2962822D1 DE 2962822 D1 DE2962822 D1 DE 2962822D1 DE 7979103393 T DE7979103393 T DE 7979103393T DE 2962822 T DE2962822 T DE 2962822T DE 2962822 D1 DE2962822 D1 DE 2962822D1
Authority
DE
Germany
Prior art keywords
preparing
same
anthracycline derivatives
new anthracycline
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979103393T
Other languages
English (en)
Inventor
Toshikazu Oki
Akihiro Yoshimoto
Taiji Inui
Tomio Takeuchi
Hamao Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Original Assignee
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Ocean Co Ltd filed Critical Sanraku Ocean Co Ltd
Application granted granted Critical
Publication of DE2962822D1 publication Critical patent/DE2962822D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE7979103393T 1978-09-20 1979-09-11 New anthracycline derivatives and process for preparing the same Expired DE2962822D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11550778A JPS5543012A (en) 1978-09-20 1978-09-20 Novel anthracycline derivatine and its preparation

Publications (1)

Publication Number Publication Date
DE2962822D1 true DE2962822D1 (en) 1982-07-01

Family

ID=14664222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979103393T Expired DE2962822D1 (en) 1978-09-20 1979-09-11 New anthracycline derivatives and process for preparing the same

Country Status (4)

Country Link
US (1) US4267312A (de)
EP (1) EP0012159B1 (de)
JP (1) JPS5543012A (de)
DE (1) DE2962822D1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6023679B2 (ja) * 1979-07-13 1985-06-08 メルシャン株式会社 ロドマイシン群抗生物質とその製造法
JPS5648893A (en) * 1979-09-07 1981-05-02 Sanraku Inc Preparation of anthracycline glycoside
DE3071391D1 (en) * 1979-09-07 1986-03-13 Sanraku Ocean Co 2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same
CH648327A5 (de) * 1980-10-16 1985-03-15 Hoffmann La Roche Anthracycline.
JPS57159496A (en) * 1981-03-28 1982-10-01 Sanraku Inc Preparation of adriamycin
JPS57165399A (en) 1981-04-03 1982-10-12 Sanraku Inc Novel anthracycline antibiotic substance and its preparation
US4471052A (en) * 1982-01-18 1984-09-11 Adria Laboratories, Inc. Biosynthesis of simplified anthracyclines
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
IT1155446B (it) * 1982-12-23 1987-01-28 Erba Farmitalia Procedimento per la purificazione di glucosidi antraciclinonici mediante adsobimento selettivo su resine
GB8421491D0 (en) * 1984-08-24 1984-09-26 Erba Farmitalia Anthracycline glycosides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039736A (en) * 1976-04-15 1977-08-02 Bristol-Myers Company Antibiotic compounds marcellomycin and musettamycin
CH637160A5 (fr) * 1976-10-05 1983-07-15 Microbial Chem Res Found Procede de fabrication de glucosides anthracyclines.
GB1542920A (en) * 1976-12-22 1979-03-28 Farmaceutici Italia Antitumour glycosides

Also Published As

Publication number Publication date
EP0012159A1 (de) 1980-06-25
EP0012159B1 (de) 1982-05-12
JPS5543012A (en) 1980-03-26
US4267312A (en) 1981-05-12

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANRAKU INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee