DE2702537A1 - Neue piperazinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel - Google Patents

Neue piperazinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Info

Publication number
DE2702537A1
DE2702537A1 DE19772702537 DE2702537A DE2702537A1 DE 2702537 A1 DE2702537 A1 DE 2702537A1 DE 19772702537 DE19772702537 DE 19772702537 DE 2702537 A DE2702537 A DE 2702537A DE 2702537 A1 DE2702537 A1 DE 2702537A1
Authority
DE
Germany
Prior art keywords
piperazine
piperazinyl
cyclohexylamine
methyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19772702537
Other languages
German (de)
English (en)
Other versions
DE2702537C2 (de
Inventor
Camillo Corvi-Mora
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CORVI CAMILLO SpA
Camillo Corvi SpA
Original Assignee
CORVI CAMILLO SpA
Camillo Corvi SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CORVI CAMILLO SpA, Camillo Corvi SpA filed Critical CORVI CAMILLO SpA
Publication of DE2702537A1 publication Critical patent/DE2702537A1/de
Application granted granted Critical
Publication of DE2702537C2 publication Critical patent/DE2702537C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2702537A 1976-01-23 1977-01-21 N-Cyclohexyl-piperazino-acetamide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel Expired DE2702537C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19517/76A IT1054961B (it) 1976-01-23 1976-01-23 Derivati della piperazina adatti come agenti anti ulcera

Publications (2)

Publication Number Publication Date
DE2702537A1 true DE2702537A1 (de) 1977-07-28
DE2702537C2 DE2702537C2 (de) 1987-03-12

Family

ID=11158695

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2702537A Expired DE2702537C2 (de) 1976-01-23 1977-01-21 N-Cyclohexyl-piperazino-acetamide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Country Status (9)

Country Link
US (2) US4123530A (US06633782-20031014-M00005.png)
JP (1) JPS52111583A (US06633782-20031014-M00005.png)
BE (1) BE850628A (US06633782-20031014-M00005.png)
CH (1) CH624944A5 (US06633782-20031014-M00005.png)
DE (1) DE2702537C2 (US06633782-20031014-M00005.png)
FR (1) FR2338938A1 (US06633782-20031014-M00005.png)
GB (1) GB1567958A (US06633782-20031014-M00005.png)
IT (1) IT1054961B (US06633782-20031014-M00005.png)
NL (1) NL7700425A (US06633782-20031014-M00005.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035957A1 (en) * 1997-02-14 1998-08-20 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
WO2011000945A2 (en) 2009-07-03 2011-01-06 Nensius Research A/S Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1054961B (it) * 1976-01-23 1981-11-30 Corvi Camillo Spa Derivati della piperazina adatti come agenti anti ulcera
US4666911A (en) * 1981-07-14 1987-05-19 Taiho Pharmaceutical Company Limited Allophanoylpiperazine compound and analgesic composition containing same as active ingredient
IT1150759B (it) * 1982-04-05 1986-12-17 Corvi Camillo Spa Complessi organometallici di n-cicloesil-piperazino-acetammidi o propionammidi, loro preparazione e impiego come farmaci antiulcera-antisecretivi-tamponanti
US4477646A (en) * 1983-08-24 1984-10-16 The Dow Chemical Company Piperazinoethyl ureas
JPS6147466A (ja) * 1984-08-10 1986-03-07 Dainippon Pharmaceut Co Ltd アミン誘導体
US5182284A (en) * 1990-01-26 1993-01-26 Taiho Pharmaceutical Co., Ltd. Piperazine compounds, processes for preparation thereof and medical uses thereof
US6048900A (en) * 1998-02-13 2000-04-11 Bayer Corporation Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
US6245817B1 (en) 1997-02-14 2001-06-12 Bayer Corporation NPY5 receptor antagonists and methods for using same
ATE432267T1 (de) * 2002-06-24 2009-06-15 Janssen Pharmaceutica Nv Verfahren zur herstellung von n-(2,6- dimethylphenyl)-2-piperazin-1-ylacetamid
JP5838628B2 (ja) * 2011-07-25 2016-01-06 東ソー株式会社 Ｎ−アルキルピペラジン類の製造方法
WO2019079243A1 (en) * 2017-10-17 2019-04-25 Albert Einstein College Of Medicine, Inc. MITOFUSIN ACTIVATORS AND USES THEREOF

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1186495A (en) * 1968-02-20 1970-04-02 Delalande Sa 0-[3-(4-Fluorobenzoyl) Proplyl]-4-Substituted Piperazines, their Acid Addition Salts and their method of preparation
DE1795375A1 (de) * 1968-09-21 1972-01-05 Boehringer Mannheim Gmbh Basische AEther und Verfahren zur Herstellung derselben
DE2034625A1 (US06633782-20031014-M00005.png) * 1969-08-14 1971-02-25
IT1054961B (it) * 1976-01-23 1981-11-30 Corvi Camillo Spa Derivati della piperazina adatti come agenti anti ulcera

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ehrhart-Ruschig: Bd. 2, 1972, S. 94, 95 u. 99 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035957A1 (en) * 1997-02-14 1998-08-20 Bayer Corporation Amide derivatives as selective neuropeptide y receptor antagonists
WO2011000945A2 (en) 2009-07-03 2011-01-06 Nensius Research A/S Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns
WO2011000945A3 (en) * 2009-07-03 2011-02-24 Nensius Research A/S Aminoalkamides for use in the treatment of inflammatory, degenerative or demyelinating diseases of the cns

Also Published As

Publication number Publication date
BE850628A (fr) 1977-05-16
JPS52111583A (en) 1977-09-19
FR2338938A1 (fr) 1977-08-19
JPS6242905B2 (US06633782-20031014-M00005.png) 1987-09-10
US4123530A (en) 1978-10-31
FR2338938B1 (US06633782-20031014-M00005.png) 1979-10-05
GB1567958A (en) 1980-05-21
IT1054961B (it) 1981-11-30
US4278796A (en) 1981-07-14
CH624944A5 (US06633782-20031014-M00005.png) 1981-08-31
NL7700425A (nl) 1977-07-26
DE2702537C2 (de) 1987-03-12

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee