DE2620891C3 - Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoff - Google Patents
Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder ProthesenverankerungswerkstoffInfo
- Publication number
- DE2620891C3 DE2620891C3 DE2620891A DE2620891A DE2620891C3 DE 2620891 C3 DE2620891 C3 DE 2620891C3 DE 2620891 A DE2620891 A DE 2620891A DE 2620891 A DE2620891 A DE 2620891A DE 2620891 C3 DE2620891 C3 DE 2620891C3
- Authority
- DE
- Germany
- Prior art keywords
- bone
- calcium phosphate
- solid
- resorbable
- composite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000463 material Substances 0.000 title claims description 26
- 210000000988 bone and bone Anatomy 0.000 title claims description 18
- 239000002131 composite material Substances 0.000 title claims description 6
- 239000007787 solid Substances 0.000 title claims description 4
- 238000004873 anchoring Methods 0.000 title claims description 3
- 239000000316 bone substitute Substances 0.000 title description 3
- 239000001506 calcium phosphate Substances 0.000 claims description 23
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 23
- 235000011010 calcium phosphates Nutrition 0.000 claims description 22
- 238000006116 polymerization reaction Methods 0.000 claims description 5
- 229920002988 biodegradable polymer Polymers 0.000 claims 1
- 239000004621 biodegradable polymer Substances 0.000 claims 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 17
- 229920000642 polymer Polymers 0.000 description 10
- 239000007943 implant Substances 0.000 description 8
- 239000011148 porous material Substances 0.000 description 6
- 239000000203 mixture Substances 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 4
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 description 3
- 230000008468 bone growth Effects 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 229920001432 poly(L-lactide) Polymers 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 2
- 241000050051 Chelone glabra Species 0.000 description 1
- 229920001651 Cyanoacrylate Polymers 0.000 description 1
- 208000005422 Foreign-Body reaction Diseases 0.000 description 1
- MWCLLHOVUTZFKS-UHFFFAOYSA-N Methyl cyanoacrylate Chemical compound COC(=O)C(=C)C#N MWCLLHOVUTZFKS-UHFFFAOYSA-N 0.000 description 1
- 208000006735 Periostitis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000004068 calcium phosphate ceramic Substances 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 239000011872 intimate mixture Substances 0.000 description 1
- 239000012705 liquid precursor Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 210000003460 periosteum Anatomy 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- DCKVNWZUADLDEH-UHFFFAOYSA-N sec-butyl acetate Chemical compound CCC(C)OC(C)=O DCKVNWZUADLDEH-UHFFFAOYSA-N 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 230000009026 tissue transition Effects 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2620891A DE2620891C3 (de) | 1976-05-12 | 1976-05-12 | Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoff |
| NL7704659A NL7704659A (nl) | 1976-05-12 | 1977-04-28 | Beendervervangings-, beenderverbindings- of prothesenverankeringsmateriaal. |
| AT299377A AT352867B (de) | 1976-05-12 | 1977-04-28 | Knochenersatz-knochenverbund-oder prothesen- verankerungswerkstoff und verfahren zu seiner herstellung |
| GB19368/77A GB1562758A (en) | 1976-05-12 | 1977-05-09 | Bone replacement bone joining or prosthesis anchoring material |
| IT23371/77A IT1085566B (it) | 1976-05-12 | 1977-05-10 | Materiale per sostituzione di ossa,giunzione di ossa o ancoraggio di protesi |
| US05/796,165 US4192021A (en) | 1976-05-12 | 1977-05-12 | Bone replacement or prosthesis anchoring material |
| CH597177A CH632158A5 (de) | 1976-05-12 | 1977-05-12 | Knochenersatz-, knochenverbund- oder prothesenverankerungswerkstoff. |
| FR7714604A FR2350826A1 (fr) | 1976-05-12 | 1977-05-12 | Materiau de remplacement des os, d'assemblage des os et d'ancrage des protheses et procede pour sa fabrication |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2620891A DE2620891C3 (de) | 1976-05-12 | 1976-05-12 | Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoff |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2620891A1 DE2620891A1 (de) | 1977-11-17 |
| DE2620891B2 DE2620891B2 (OSRAM) | 1979-01-25 |
| DE2620891C3 true DE2620891C3 (de) | 1989-06-29 |
Family
ID=5977695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2620891A Expired DE2620891C3 (de) | 1976-05-12 | 1976-05-12 | Fester, resorbierbarer Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoff |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE2620891C3 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2620890C3 (de) * | 1976-05-12 | 1987-09-10 | Battelle-Institut eV, 6000 Frankfurt | Plastische Masse auf der Basis von gesinterten Calciumphosphaten für implantierbare Knochenersatz-, Knochenverbund- oder Prothesenverankerungswerkstoffe |
| FR2364644B1 (fr) * | 1976-09-20 | 1981-02-06 | Inst Nat Sante Rech Med | Nouveau materiau de prothese osseuse et son application |
| DE2843963A1 (de) | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
| DE2807132C2 (de) * | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
| DE2827529C2 (de) * | 1978-06-23 | 1982-09-30 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbarer Knochenersatzwerkstoff bestehend aus einem Metallkern und aus bioaktiven, gesinterten Calciumphosphat-Keramik-Partikeln und ein Verfahren zu seiner Herstellung |
| DE2850586C2 (de) * | 1978-11-22 | 1982-05-27 | Battelle-Institut E.V., 6000 Frankfurt | Einlage zur Endoprothesenverankerung |
| DK154260C (da) * | 1981-02-20 | 1989-05-22 | Mundipharma Gmbh | Fremgangsmaade til fremstilling af et knogleimplantat af braendt tricalciumphosphat, specielt til udfyldning af hulrum eller til sammensaetning af knogledele efter fraktur. |
| DE3424777C2 (de) * | 1983-07-08 | 1995-08-03 | Kyushu Refractories | Künstliche Zahnmaterialien |
| DE3414924A1 (de) * | 1984-04-19 | 1985-10-31 | Klaus Dr.med. Dr.med.habil. 8000 München Draenert | Beschichtetes verankerungsteil fuer implantate |
| US4839215A (en) * | 1986-06-09 | 1989-06-13 | Ceramed Corporation | Biocompatible particles and cloth-like article made therefrom |
| DE3825211A1 (de) * | 1988-07-25 | 1990-02-01 | Henkel Kgaa | Verbesserte koerperresorbierbare knochenwachse (iii) |
| DE3826915A1 (de) * | 1988-08-09 | 1990-02-15 | Henkel Kgaa | Neue werkstoffe fuer den knochenersatz und knochen- bzw. prothesenverbund |
| DE4120325A1 (de) * | 1991-06-20 | 1992-12-24 | Merck Patent Gmbh | Implantatwerkstoff |
| DE102004035182B4 (de) * | 2004-07-14 | 2008-05-29 | Innovent E.V. Technologieentwicklung | Implantatmaterial, ein Verfahren zu seiner Herstellung und seine Verwendung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3609867A (en) * | 1969-03-10 | 1971-10-05 | Research Corp | Plastic bone composition |
-
1976
- 1976-05-12 DE DE2620891A patent/DE2620891C3/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2620891B2 (OSRAM) | 1979-01-25 |
| DE2620891A1 (de) | 1977-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |