DE259493C - - Google Patents
Info
- Publication number
- DE259493C DE259493C DENDAT259493D DE259493DA DE259493C DE 259493 C DE259493 C DE 259493C DE NDAT259493 D DENDAT259493 D DE NDAT259493D DE 259493D A DE259493D A DE 259493DA DE 259493 C DE259493 C DE 259493C
- Authority
- DE
- Germany
- Prior art keywords
- foam
- amount
- disinfectants
- remedies
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000000249 desinfective Effects 0.000 claims description 12
- 239000006260 foam Substances 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 8
- 200000000019 wound Diseases 0.000 claims description 7
- 239000000084 colloidal system Substances 0.000 claims description 6
- 239000000645 desinfectant Substances 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000002085 persistent Effects 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 2
- 235000014103 egg white Nutrition 0.000 claims description 2
- 210000000969 egg white Anatomy 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 claims description 2
- 235000011852 gelatine desserts Nutrition 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000000875 corresponding Effects 0.000 claims 1
- 238000005755 formation reaction Methods 0.000 claims 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 210000004369 Blood Anatomy 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- 206010018987 Haemorrhage Diseases 0.000 description 1
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 description 1
- 210000004400 Mucous Membrane Anatomy 0.000 description 1
- 241000209051 Saccharum Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000740 bleeding Effects 0.000 description 1
- 231100000319 bleeding Toxicity 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007911 effervescent powder Substances 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- KEAYESYHFKHZAL-UHFFFAOYSA-N sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
KAISERLICHESIMPERIAL
PATENTAMT.PATENT OFFICE.
Den Gegenstand der Erfindung bildet ein Verfahren zur Herstellung von zur Behandlung
von Wunden oder Körperhöhlen bestimmten Desinfektions- oder Heilmitteln.
Das neue Verfahren kennzeichnet sich dadurch, daß einer einen Desinfektions- oder
Heilstoff enthaltenden aufbrausenden. Mischung ein die Schaumbildung begünstigender
Stoff, ein Kolloid, Gelatine, Eiweiß o. dgl.The subject matter of the invention is a process for the production of disinfectants or medicaments intended for the treatment of wounds or body cavities.
The new method is characterized by the fact that an effervescent substance containing a disinfectant or medicinal substance. Mixture of a foam-promoting substance, a colloid, gelatin, egg white or the like.
in solcher Menge zugesetzt wird, daß sich beim Aufbrausen der Mischung ein stehenbleibender Schaum nach Art eines zähen Seifenschaumes bildet.is added in such an amount that when the mixture effervesces a persistent Forms foam in the manner of a tough soap foam.
Wird ein nach dem neuen Verfahren vorbereitetes Desinfektions- oder Heilmittel in eine Wunde oder Körperhöhle eingeführt und mit Feuchtigkeit in \rerbindung gebracht, so bildet sich ein die Wunde oder Körperhöhle bis in die äußersten Verzweigungen -hinein ausfüllender und hermetisch abschließender Schaumpflock, so daß die unbequeme, eine geübte Hand erfordernde Anwendung von Sonden, Spritzen u. dgl. in Fortfall kommt, während andererseits der lange stehenbleibende dichte Schaum das Desinfektions- oder Heilmittel in dauernder Berührung mit den Wänden der Wunde oder Körperhöhle hält und vermöge seiner Adhäsion an diesen Wänden eine gründliche Einwirkung sichert.Is a prepared by the new process disinfecting or remedies introduced into a wound or body cavity and brought into contact with moisture in \ r Getting Connected, so to form a wound or body cavity up to the outermost branches -hinein fills and hermetically sealed foam peg, so that the The inconvenient use of probes, syringes and the like, which requires a skilled hand, is no longer necessary, while on the other hand the dense foam that remains for a long time keeps the disinfectant or healing agent in constant contact with the walls of the wound or body cavity and, by virtue of its adhesion to these walls, does one thorough exposure ensures.
Der Zusatz des Schaumbildners ist naturgemäß innerhalb des Rahmens der angestrebten Wirkung so gering wie nur möglich zu halten, damit in der Mischung der wirksame Bestandteil in möglichst ausgiebigem Maße vorwaltet.The addition of the foaming agent is naturally within the scope of that which is desired To keep the effect as low as possible so that the active ingredient in the mixture is as extensive as possible prevails.
Es ist bereits bekannt (vgl. z. B. die britische Patentschrift 10294/1895) zur innerlichen Behandlung bestimmten Heil- und Desinfektionsstoffen Brausepulver zuzusetzen, sei es, um ihren Geschmack zu verbessern, oder sei es, um ein schnelles Zerfallen von aus den betreffenden Stoffen hergestellten Tabletten und dadurch eine raschere Auflösung zu bewirken. Auch ist es bekannt, den eben erwähnten Mischungen Gummistoffe, also Kolloide, zuzusetzen. Hierbei handelte es sich aber niemals um die Erzeugung eines stehenbleibenden Schaumes. Die Kolloide sollen vielmehr nur als Bindemittel dienen. Sie werden demgemäß auch nur in so geringen Mengen verwendet, daß die Erzeugung" eines stehenbleibenden Schaumes durch Zusammenbringen der bekannten Präparate mit Wasser nicht möglich ist. Demgegenüber beruht die vorliegende Erfindung gerade darauf, die Menge der schaumbildenden Kolloide im fertigen Produkt so hoch zu bemessen, daß ein dichter stehenbleibender Schaum entsteht, der ein Hineintreiben des Heil- oder Desinfektionsmittels durch die Gasentwicklung in die fernsten Winkel der Wunde oder Körperhöhle ermöglicht und die Heil- oder Desinfek-It is already known (see, for example, British patent specification 10294/1895) for internal To treat certain medicinal products and disinfectants, add effervescent powder it to improve its taste, or be it to make it disintegrate quickly relevant substances produced tablets and thereby to bring about a faster dissolution. It is also known to add rubber substances, that is to say colloids, to the mixtures just mentioned. Here it was but never about the production of a permanent foam. The colloids rather, they should only serve as a binding agent. Accordingly, they will only be so small Quantities used that the creation of "a persistent foam by bringing together." of the known preparations with water is not possible. In contrast, the present invention is based precisely on to measure the amount of foam-forming colloids in the finished product so high that a dense, permanent foam is created, which drifts in the medicinal or disinfectant made possible by the development of gas into the furthest corners of the wound or body cavity and the healing or disinfection
tionsstoffe zur innigen langdauernden Anhaftung an die Schleimhäute bringt. Versuche haben ergeben, daß hierfür eine Menge der Kolloide in Höhe von etwa 5 Prozent der Gesamtmasse ausreicht.brings tion substances to the intimate long-term adhesion to the mucous membranes. try have shown that for this an amount of the colloids in the amount of about 5 percent of the Total mass is sufficient.
Infolge der Entwicklung eines lange stehenbleibenden dichten Schaumes eignen sich die nach dem neuen Verfahren hergestellten Mischungen u. a. auch vorzüglich dazu, Blutungen in Körperhöhlungen zum Stillstand zu bringen, indem der steife Schaum das in der Mischung enthaltene Blut- j Stillungsmittel in dauernder inniger Beruh- j rung mit den Wundkanälen hält. jDue to the development of a dense foam that lasts for a long time, it is suitable the mixtures produced by the new process inter alia. also excellent to stop bleeding in body cavities by the stiff foam the blood contained in the mixture j Keeps the breastfeeding agent in constant intimate contact with the wound canals. j
Zur Desinfektion von Körperhöhlen eignet sich beispielsweise folgende Mischung: Acidum tartaricum 100, Natrium bicarbonicum 100, Saccharum 50, Gelatine 20, ein Desinficiens (z. B. Sublamin 1 oder Salizylsäure 10).The following mixture, for example, is suitable for disinfecting body cavities: Acidum tartaricum 100, sodium bicarbonicum 100, saccharum 50, gelatine 20, a disinfectant (e.g. sublamine 1 or salicylic acid 10).
Die Mischung wird zweckmäßig in Tablettenform gebracht.The mixture is expediently brought into tablet form.
Claims (1)
Publications (1)
Publication Number | Publication Date |
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DE259493C true DE259493C (en) |
Family
ID=517213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DENDAT259493D Active DE259493C (en) |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE259493C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10327432A1 (en) * | 2003-06-18 | 2005-01-05 | Beiersdorf Ag | Reactive foaming of a skin-care preparation or cosmetic and/or dermatological preparation uses spatially separated product strips, one containing (bi)carbonate and another an acid |
-
0
- DE DENDAT259493D patent/DE259493C/de active Active
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10327432A1 (en) * | 2003-06-18 | 2005-01-05 | Beiersdorf Ag | Reactive foaming of a skin-care preparation or cosmetic and/or dermatological preparation uses spatially separated product strips, one containing (bi)carbonate and another an acid |
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