DE2351893A1 - CARRIER IMPROVED WITH ACTIVE INGREDIENTS - Google Patents

Description

D R. B E R G DIP L.-IN G. STAPF

piPL.-ING. SCHWABE DR. TR. SANDMAIR

PATENTANWÄLTE 8 MÖNCHEN 80 · MAUERKIRCHER8TR. 45

DR. WILHELM HÜRKA IU LIESERERÜCKE

Eräger soaked with active ingredients

Attorney's file 2% 478 October 16, 1973

409 8 36/0 966

The present invention relates to an iDräger, in particular Xüohlein, impregnated with active ingredients Based on paper, plastic or textile material, 'preferably for disinfection or to protect hand surfaces, which Carrier, air-tight or moisture-tight, enclosed in a foil, in particular an aluminum foil is and consists in that the carrier is impregnated with a composition which, in addition to the active ingredient or ingredients contains a film-forming substance.

Germs have long been used to protect hands from aggressive media such as chemicals, but also rays etc. rubber gloves used. These have a number of disadvantages, only the great degradation of the The ability to touch and the severe impairment of manual dexterity should be mentioned.

For this reason, protective creams have been developed (occupational safety creams, barrier creams (etc.), which, after application on the hands to form a protective film for a period of time. These preparations come in tubes, or cans in bottles as a lotion or emulsion. Protection can also be achieved by dipping in solutions, emulsions, etc. or by spraying an aerosol on the hands, ■ However, these methods are inadequate.

Before using the preparations, it is advisable to wash with soap and water (cleaning) of the to be treated To carry out games. As a rule, the preparation is then applied to hands that are still damp these films have poor adherence if the last bit of moisture is not completely removed · The film is subsequently infiltrated and local "flaking" takes place. The film is removed mechanically and after a short time no longer offers protection

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According to the present invention, the hands are provided with a protective film in the form of an invisible glove overdrawn · This handshake shows the defects mentioned above not on. In practice this is done so "that a carrier, e.g. a little paper based on a textile, Plastic material, among other things, or a sponge or cotton ball is soaked in a solution or emulsion. With This wearer's hands are now cleaned and at the same time provided with an adhesive and protective film. It is important here the intimate writing of the solution, so really a good one Contact with the skin is made. This is how it arises a good adhesive layer, which in turn enables the protective film to adhere closely.

The protective film can contain active ingredients such as disinfectants, skin care products, sun protection substances, Radiation protection agents, among other things, especially in connection with In this way a surprising remanent effect could be achieved with disinfectants «, one such Protective composition can consist of the following components: solvent, film former, active ingredient, Skin care substances, adhesives, perfume, but not always have to contain all components. It can be selected on a case-by-case basis which components are used. However, a film former is always used, preferably in Combination with a disinfectant or skin protectant. Depending on the behavior of the film former, a corresponding one must be used Solvents can be used.

The soaked lüchlein is in if necessary coated aluminum foil or plastic foil welded in.

The following substances are preferably used as film formers:.

1) Macromolecules or actual film formers

a) Natural mucilage: gums, alginates, dextrans

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- 4 Ta) Semi-synthetic macromolecules: methyl and ethyl cellulose esters or -ether e.g. Modocoll, Ihylose,

Carboxymethyl cellulose
c) fully synthetic macromolecules: polyvinyl alcohol, polyvinylpyrrolidone and polyacrylic acids.

2) Fats, oils, waxes: e.g. wool fatty alcohol, cetyl alcohol, Stearate, petroleum jelly, paraffin oil, polyethylene glycols

3) silicone oil.

The following substances are preferred as solvents: water, alcohols diluted or concentrated, Mineral spirits, glycerine, polyglycol.

The following substances in particular come into consideration as active ingredients:
1) disinfectant:

a) ampholytes:
M-hexadecylglycine,

N |, 2 / T2-dodecylaminoethyl) -amino7äth.yliglycine, 3,5 to ££ [2 / T-2 dodecylaminoethyl) amino7ethyl 3

amino-methyl ^ - salicylic acid,

N - £ 2 £ "{2 octylaminoethyl) - amino- ~ ethyl ^ glycine, N - (3 - dodecylaminopropyl) - ß-aminobutyric acid, II - (3 - dodecyloxypropyl) - ß-aminobutyric acid,

b) Quaternary ammonium compounds: dodecyl - dicblorobenzylammoniam chloride,

gluconate, lactate, cyclamate; Dodecyldimethyl - benzylammonium chloride,

-gluconate, -lactate, -wyclamatj tetradecyldimethyl - benzylammonium chloride,

gluconate, lactate, cyclamate; Dodecyldimethyl - ethylbenzylammonium chloride,

gluconate, lactate, cyclamate; Hexadecyltrimethyl - ammonium chloride,

-gluconate, -lactate, -cyclamate

409836/0966

c) Salts of chlorhexidine di: 1,1'-hexamethylene - bis - / __ 5-p-ohlorphenyl'biguanide _> _7 ^r , mainly gluconate, lactate, chloride, acetates

d) aldehydes:

Salicylaldehydes, p-hydroxybejizaldehydes, benzaldehydes

e) phenol derivatives:
O-phenyl - phenol - Na

2.2 '- dihydroxy - 5.5 ^l dichlorodiphenylmethane ο - benzyl - ρ - chi or phenol
f) hexachlorophene

2) Sunscreens of all kinds:
e.g. ρ - aminobenzoates

Salicylates

Anthranyl salts

Zincoside

3) Active ingredients against radiation damage, e.g. brominated oleic acid

4) Protective materials against dust:
Stearic acid, waxes'

5) Protective substances against chromium, lead and other heavy metals: complexing agents, hydroquinones.

The following substances can be used as skin care products:

a) Refatting and superfatting agents Partial glycerol fatty acid esters, Glycerinj Myglyolöl, Softigen, Softisan, Lanolin

b) Substances that promote wound bruising and regeneration: Allantoin, yifamin A, cod liver oil, vitamin C.

Example 1: 0.2 g of Modocoll (ethyl hydroxyethyl cellulose) is left Cold swell in 87.8 g water per liter. 2 g of chlorhexidine gluconate and 10 g of glycerol are stirred in and mixed Well done. Perfume is added at will. Example 2: 0.2 g of Carbopol 934 is left in 95.8 g Water swell. The pH is then increased with iriethanolamine

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6.5 set. 2 g of Preventol OE extra (o-phenylphenolB-l-sodium) are dissolved in this mixture and then 2 g of Purcellin, water-soluble, are added and stirred well.

Example 3: 0.2g irimethyllaurylammonium chloride are dissolved in 5 g of isopropanol. 5 g of Softigen are added and the solution is stirred. 0.5 g of Aerosil are in 89.3 g Dimethylpolysiloxane AK 350 made into a paste and the former solution slowly added "It is then homogenized" Example 4: 1g Kelkosol (sodium alginate.) Leaves 90.5 g of water in which 1.5 g of salicylaldehyde are dissolved, swell cold. You then add 5 g of polyglycol 300 and 2 g of allantoin to and homogenized Example 5: 0.5 g of Methocel HG is left in Swell 20 g of water. 2 g of blorbexidine lactate are added. Separately, 2 g of glycerol monostearate, .5 g of glycerol and 70.5 g of isopropanol stirred into a solution, this solution is added to the former and mixed well. Example 6: 58 g of Ph.enylsilioonöl, 40 g isopropanol and 2 g of dodecyl-aminopropyl-ß-aminobutyric acid are mixed with one another Example 7, stirred cold to form a solution: 1.5 g of Kollidon are allowed to swell in 96 g of 70 tiger alcohol. 0.5 g of dodecyl-aminoethyl-aminoethyl-glycine dissolve in 2 g legomuls 0 and stir, now the two components.

Example 8: 0.5 g of carhopol are homogenized in 69.8 g of water. D _a to one adds 1.0 g Triätbanolamin and 0.2 g of sodium hydroxide, "A mixture of 2.5 g and 25.0 g Arhopal surgical spirit is emulsified with the first solution. 1.0 g of chlorhexidine hydrochloride is mixed in this emulsion and homogenized »

All of these examples describe solutions or thin jellies with which paper towels or the like are used are soaked, which are then welded in aluminum foil.

40 9 836/0966

Claims (1)

DR, WILHELM HOBKA IN LIESERBRÜOKE (ΚΑΕΜΈΝ) Claims (1) Carriers impregnated with active ingredients, in particular handkerchiefs based on paper, plastic or textile material, preferably for disinfection or to protect the surfaces of the hands, which carrier is airtight "or moisture-proof in a film, in particular an optionally coated one Aluminum foil, which is enclosed, characterized that the carrier is impregnated with a composition which, in addition to the active ingredient or the active ingredients, also forms a film Contains substance. 2. Carrier soaked with active ingredients according to claim. 1, characterized in that it is used as a film-forming substance Macromolecules or actual film formers such as natural mucilages ι gums, alginates, dextranesj semi-synthetic Macromolecules: methyl and ethyl cellulose esters or ethers, e.g. Modocoll, Thylose, öärboxymethylcellulose, fully synthetic Macromolecules: polyvinyl alcohol, polyvinylpyrrolidone and polyacrylic acids, or fats, oils, waxes such as e.g. wool fatty alcohol, oetyl alcohol, stearates, petroleum jelly, Contains paraffin oil, polyethylene glycols, and silicone oil. 3 '. Carrier soaked with active ingredients according to claims 1 and 2, characterized in that it, as Active ingredient contains disinfectant. 40 9 8 36/0966 4 · Rager soaked with active ingredients, according to claim 3, characterized in that it uses ampholytes such as N-hexadecylglycine, M "£ 2 / Ts-dodecylaminoethyl) -amino7ethylj glycine 3,5 - his ^ £ j2 / ~ (- £ dodecylaminoethyl) amino__7ethyl ^ amino] methyl ^ - salicylic acid, N - £ 2 / "" (2otylaminoethyl) - amino__7-ethyl ^ - glycine, N - (3 - dodecylaminopropyl) - ß-aminobutyric acid, ΪΓ - (3 - dodecyloxypropyl ) - ß - amino "butyric acid, and / or quaternary ammonium compounds such as dodecyl-dichlorohenzylammonium chloride, -gluconate, -lactate, -cyclamate. Dodecyldimethyl-henzylammonium chloride, -gluconate, -lactate, -cyclamatej tetradecyldimethyl-henzylammonium chloride, -gluconate, -lactate, -cyclamate; Dodecyldimethylethylhenzylammonium chloride, gluconate, lactate, cyclamate; Hexadecyltrimethyl ammonium chloride, gluconate, lactate, cyclamate and / or salts of chlorhexidine di? 1,1 «-Hexamethylene - his - /, ~" 5-p-chlorophenylhiguanide__7 mainly. Gluconate, lactate, chloride, acetate and / or aldehydes such as salicylaldehydes, p-hydroxyhenzaldehydes, benzaldehydes and / or phenol derivatives such as O-phenylphenol Ha , 2,2 * -dihydroxy-5,5 'dichlorodiphenylmethane, oB _e nzyl-pchlorphenol and / or hexachlorophene contains. 5. Impregnated with active ingredients carrier according to claims 1 and 2, characterized in that it is used as Active ingredient sunscreens such as p-aminohenzoates, salicylates, anthranyl salts and zincoside. 6ο Carrier soaked with active ingredients after the Claims 1 and 2, characterized in that it contains active substances against radiation damage, e.g. chromated oleic acid, contains. 7. Carrier soaked with active ingredients according to Claims 1 and 2, characterized in that it contains protective substances against dust such as stearic acid and waxes. 409836/0966 8o Carrier soaked with active ingredients according to the Claims 1 and 2, characterized in that it contains protective substances against chromium, lead or other * heavy metals such as complexing agents and hydroquinones 9. Carrier soaked with active ingredients according to Claims 1 and 2, characterized in that it contains skin care substances, such as refatting and superfatting agents, partial glycerin fatty acid esters, glycerin, myglyol oil, Softigen, Softisan, Lanolin and / or substances that promote wound healing and regeneration, especially allantoin, Contains vitamin A, cod liver oil and vitamin O. 10. Impregnated with active ingredients carrier according to claims 1 to 9, characterized in that it is used as Solvents for the film former such as water, diluted or concentrated alcohols, mineral spirits, glycerine and Contains polyglycol. . 40 9 8 36/0966