DE2340843A1 - System zur teilchenunterscheidung - Google Patents
System zur teilchenunterscheidungInfo
- Publication number
- DE2340843A1 DE2340843A1 DE19732340843 DE2340843A DE2340843A1 DE 2340843 A1 DE2340843 A1 DE 2340843A1 DE 19732340843 DE19732340843 DE 19732340843 DE 2340843 A DE2340843 A DE 2340843A DE 2340843 A1 DE2340843 A1 DE 2340843A1
- Authority
- DE
- Germany
- Prior art keywords
- cell body
- wavelength band
- cell
- dependent
- functions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title claims description 18
- 238000000034 method Methods 0.000 claims description 42
- 210000004027 cell Anatomy 0.000 claims description 40
- 239000007788 liquid Substances 0.000 claims description 35
- 230000005855 radiation Effects 0.000 claims description 35
- 230000001419 dependent effect Effects 0.000 claims description 28
- 238000005259 measurement Methods 0.000 claims description 25
- 210000000601 blood cell Anatomy 0.000 claims description 22
- 238000010521 absorption reaction Methods 0.000 claims description 18
- 229920000642 polymer Polymers 0.000 claims description 7
- 210000004369 blood Anatomy 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 6
- 230000003204 osmotic effect Effects 0.000 claims description 6
- 210000000805 cytoplasm Anatomy 0.000 claims description 4
- 238000005286 illumination Methods 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 230000008030 elimination Effects 0.000 claims description 3
- 238000003379 elimination reaction Methods 0.000 claims description 3
- 238000005086 pumping Methods 0.000 claims description 3
- 229920002307 Dextran Polymers 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 2
- 210000005056 cell body Anatomy 0.000 claims 64
- 238000002835 absorbance Methods 0.000 claims 2
- 230000006978 adaptation Effects 0.000 claims 2
- 230000000052 comparative effect Effects 0.000 claims 2
- 229920006158 high molecular weight polymer Polymers 0.000 claims 1
- 239000000523 sample Substances 0.000 description 15
- 230000003287 optical effect Effects 0.000 description 11
- 239000003085 diluting agent Substances 0.000 description 8
- 210000004940 nucleus Anatomy 0.000 description 7
- 210000003855 cell nucleus Anatomy 0.000 description 6
- 239000000975 dye Substances 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 239000007924 injection Substances 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000000654 additive Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 108020004414 DNA Proteins 0.000 description 3
- 238000000149 argon plasma sintering Methods 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000006285 cell suspension Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000009795 derivation Methods 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000005194 fractionation Methods 0.000 description 2
- 230000031700 light absorption Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 230000035699 permeability Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 238000010561 standard procedure Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 108091093105 Nuclear DNA Proteins 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004820 blood count Methods 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 239000012470 diluted sample Substances 0.000 description 1
- 238000003113 dilution method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 235000011475 lollipops Nutrition 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 238000000790 scattering method Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000007447 staining method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1497—Particle shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
- G01N2021/4711—Multiangle measurement
- G01N2021/4716—Using a ring of sensors, or a combination of diaphragm and sensors; Annular sensor
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00280271A US3822095A (en) | 1972-08-14 | 1972-08-14 | System for differentiating particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2340843A1 true DE2340843A1 (de) | 1974-02-28 |
Family
ID=23072378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19732340843 Pending DE2340843A1 (de) | 1972-08-14 | 1973-08-13 | System zur teilchenunterscheidung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3822095A (enrdf_load_stackoverflow) |
| JP (1) | JPS4952489A (enrdf_load_stackoverflow) |
| CH (1) | CH583021A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2340843A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2196708A5 (enrdf_load_stackoverflow) |
| GB (2) | GB1425972A (enrdf_load_stackoverflow) |
| NL (1) | NL7311146A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2194368B1 (de) * | 2008-12-03 | 2019-07-17 | Grundfos Management A/S | Sensorsystem zum Erfassen und Spezifizieren von einzelnen Partikeln in einem Fluid |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3982126A (en) * | 1974-03-05 | 1976-09-21 | Outokumpu Oy | Method and device for determining particle size categories of particles dispersed in a liquid |
| US3976862A (en) * | 1975-03-18 | 1976-08-24 | Block Engineering, Inc. | Flow stream processor |
| US3960449A (en) * | 1975-06-05 | 1976-06-01 | The Board Of Trustees Of Leland Stanford Junior University | Measurement of angular dependence of scattered light in a flowing stream |
| US4070113A (en) * | 1976-05-05 | 1978-01-24 | California Institute Of Technology | Coherent optics blood cell classification system |
| US4184766A (en) * | 1976-10-28 | 1980-01-22 | Coulter Electronics, Inc. | Method and apparatus for correlating measurements of tandem sensing zones |
| DE2903625A1 (de) * | 1978-02-03 | 1979-08-09 | Rush Presbyterian St Luke | Vorrichtung zur automatischen blutanalyse |
| SE7806922L (sv) * | 1978-06-15 | 1979-12-16 | Svenska Traeforskningsinst | Forfarande och anordning for att indikera storleksfordelningen av i ett strommande medium befintliga partiklar |
| US4455376A (en) * | 1979-09-17 | 1984-06-19 | R. J. Harvey Instrument Corp. | Photometric methods for counting the particulate components of blood |
| US4338024A (en) * | 1980-05-02 | 1982-07-06 | International Remote Imaging Systems, Inc. | Flow analyzer and system for analysis of fluids with particles |
| FR2484077B1 (fr) | 1980-06-06 | 1984-07-06 | Inst Nat Sante Rech Med | Procede et dispositif de mesure de la deformabilite de cellules vivantes, notamment des globules rouges du sang |
| EP0046345A3 (en) * | 1980-08-15 | 1982-03-03 | Ortho Diagnostic Systems Inc. | Controlled hydrodynamic flow in flow cytometry systems |
| SE453128B (sv) * | 1981-10-01 | 1988-01-11 | Svenska Traeforskningsinst | Forfarande for att bestemma medelpartikelradie och/eller medelpartikellengd |
| US4798465B2 (en) * | 1986-04-14 | 1994-08-30 | Particle Measuring Syst | Particle size detection device having high sensitivity in high molecular scattering environment |
| EP0286088B1 (en) * | 1987-04-08 | 1994-09-14 | Hitachi, Ltd. | A sheath flow type flow-cell device |
| JP2635125B2 (ja) * | 1988-09-30 | 1997-07-30 | 東亜医用電子株式会社 | 核の分葉指数を求めるための粒子分析装置及び方法 |
| US5123055A (en) * | 1989-08-10 | 1992-06-16 | International Remote Imaging Systems, Inc. | Method and an apparatus for differentiating a sample of biological cells |
| US6812032B1 (en) | 1993-01-21 | 2004-11-02 | Cdc Technologies, Inc. | Apparatus and method for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
| US5728351A (en) * | 1993-01-21 | 1998-03-17 | Cdc Technologies, Inc. | Apparatus for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
| JP3039594B2 (ja) * | 1993-10-08 | 2000-05-08 | 株式会社日立製作所 | 染色試薬およびその使用方法 |
| US5840254A (en) * | 1995-06-02 | 1998-11-24 | Cdc Technologies, Inc. | Apparatus for mixing fluids for analysis |
| US6118531A (en) * | 1997-05-03 | 2000-09-12 | Hertel; Martin | Method for identifying particles in a gaseous or liquid carrier medium |
| US6020960A (en) * | 1998-02-25 | 2000-02-01 | Honeywell Inc. | System for the in-line extraction and dilution of a representative sample of a processed medium |
| US6359683B1 (en) * | 2000-04-27 | 2002-03-19 | Becton, Dickinson And Company | Method for determining the volume of particles suspended in liquids |
| US7130046B2 (en) * | 2004-09-27 | 2006-10-31 | Honeywell International Inc. | Data frame selection for cytometer analysis |
| US7283223B2 (en) * | 2002-08-21 | 2007-10-16 | Honeywell International Inc. | Cytometer having telecentric optics |
| US8329118B2 (en) * | 2004-09-02 | 2012-12-11 | Honeywell International Inc. | Method and apparatus for determining one or more operating parameters for a microfluidic circuit |
| US7641856B2 (en) * | 2004-05-14 | 2010-01-05 | Honeywell International Inc. | Portable sample analyzer with removable cartridge |
| US7630063B2 (en) * | 2000-08-02 | 2009-12-08 | Honeywell International Inc. | Miniaturized cytometer for detecting multiple species in a sample |
| US7242474B2 (en) * | 2004-07-27 | 2007-07-10 | Cox James A | Cytometer having fluid core stream position control |
| US8071051B2 (en) | 2004-05-14 | 2011-12-06 | Honeywell International Inc. | Portable sample analyzer cartridge |
| US7420659B1 (en) | 2000-06-02 | 2008-09-02 | Honeywell Interantional Inc. | Flow control system of a cartridge |
| US7471394B2 (en) * | 2000-08-02 | 2008-12-30 | Honeywell International Inc. | Optical detection system with polarizing beamsplitter |
| US7016022B2 (en) * | 2000-08-02 | 2006-03-21 | Honeywell International Inc. | Dual use detectors for flow cytometry |
| US6970245B2 (en) * | 2000-08-02 | 2005-11-29 | Honeywell International Inc. | Optical alignment detection system |
| US6700130B2 (en) * | 2001-06-29 | 2004-03-02 | Honeywell International Inc. | Optical detection system for flow cytometry |
| US7215425B2 (en) * | 2000-08-02 | 2007-05-08 | Honeywell International Inc. | Optical alignment for flow cytometry |
| US7978329B2 (en) * | 2000-08-02 | 2011-07-12 | Honeywell International Inc. | Portable scattering and fluorescence cytometer |
| US7262838B2 (en) * | 2001-06-29 | 2007-08-28 | Honeywell International Inc. | Optical detection system for flow cytometry |
| US20060263888A1 (en) * | 2000-06-02 | 2006-11-23 | Honeywell International Inc. | Differential white blood count on a disposable card |
| US7061595B2 (en) * | 2000-08-02 | 2006-06-13 | Honeywell International Inc. | Miniaturized flow controller with closed loop regulation |
| US7277166B2 (en) * | 2000-08-02 | 2007-10-02 | Honeywell International Inc. | Cytometer analysis cartridge optical configuration |
| US7612871B2 (en) * | 2004-09-01 | 2009-11-03 | Honeywell International Inc | Frequency-multiplexed detection of multiple wavelength light for flow cytometry |
| US7630075B2 (en) * | 2004-09-27 | 2009-12-08 | Honeywell International Inc. | Circular polarization illumination based analyzer system |
| US7688427B2 (en) | 2005-04-29 | 2010-03-30 | Honeywell International Inc. | Particle parameter determination system |
| JP4995197B2 (ja) * | 2005-07-01 | 2012-08-08 | ハネウェル・インターナショナル・インコーポレーテッド | ３ｄ流体力学的集束を有する成形カートリッジ |
| CN101252994B (zh) * | 2005-07-01 | 2011-04-13 | 霍尼韦尔国际公司 | 用于红血细胞分析的微流体卡 |
| WO2007005974A2 (en) * | 2005-07-01 | 2007-01-11 | Honeywell International, Inc. | A flow metered analyzer |
| US7843563B2 (en) * | 2005-08-16 | 2010-11-30 | Honeywell International Inc. | Light scattering and imaging optical system |
| EP1963866B1 (en) * | 2005-12-22 | 2018-05-16 | Honeywell International Inc. | Hematological analyzer system with removable cartridge |
| JP5175213B2 (ja) * | 2005-12-22 | 2013-04-03 | ハネウェル・インターナショナル・インコーポレーテッド | 携帯用サンプル分析システム |
| EP1963817A2 (en) * | 2005-12-22 | 2008-09-03 | Honeywell International Inc. | Portable sample analyzer cartridge |
| CN101389947B (zh) * | 2005-12-29 | 2013-08-21 | 霍尼韦尔国际公司 | 微流格式的测定工具 |
| JP5324598B2 (ja) | 2007-12-04 | 2013-10-23 | パーティクル・メージャーリング・システムズ・インコーポレーテッド | 非直角粒子検出システム及び方法 |
| US8742368B2 (en) | 2008-02-01 | 2014-06-03 | Cambridge Consultants Limited | Device and method for measuring scattering of radiation |
| US20100034704A1 (en) * | 2008-08-06 | 2010-02-11 | Honeywell International Inc. | Microfluidic cartridge channel with reduced bubble formation |
| US8037354B2 (en) | 2008-09-18 | 2011-10-11 | Honeywell International Inc. | Apparatus and method for operating a computing platform without a battery pack |
| US8741234B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US8741235B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Two step sample loading of a fluid analysis cartridge |
| US8741233B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US8663583B2 (en) | 2011-12-27 | 2014-03-04 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US9316635B2 (en) * | 2013-03-15 | 2016-04-19 | Iris International, Inc. | Sheath fluid systems and methods for particle analysis in blood samples |
| TR201809959T4 (tr) | 2013-03-15 | 2018-08-27 | Iris Int Inc | Numune boyanması ve işlenmesine yönelik yöntem ve bileşim. |
| US9857361B2 (en) | 2013-03-15 | 2018-01-02 | Iris International, Inc. | Flowcell, sheath fluid, and autofocus systems and methods for particle analysis in urine samples |
| WO2016130489A1 (en) | 2015-02-09 | 2016-08-18 | Slingshot Biosciences, Inc. | Hydrogel particles with tunable optical properties and methods for using the same |
| KR101855490B1 (ko) * | 2016-01-22 | 2018-05-08 | 한국과학기술원 | 점탄성유체와 점성유체의 병행층류를 이용한 미소 입자 분리 및 세정 방법 |
| US11577994B2 (en) * | 2018-03-22 | 2023-02-14 | Sumitomo Electric Industries, Ltd. | Optical fiber manufacturing method and manufacturing device |
| CA3165821A1 (en) | 2020-01-24 | 2021-07-29 | Jeffrey Kim | Compositions and methods for cell-like calibration particles |
| JP2023524524A (ja) | 2020-05-04 | 2023-06-12 | スリングショット バイオサイエンシーズ， インコーポレイテッド | 多重化アッセイのためのパッシブ光学バーコード付与のための組成物および方法 |
| JP2024539956A (ja) | 2021-10-29 | 2024-10-31 | スリングショット バイオサイエンシーズ， インコーポレイテッド | フィーダー細胞としておよび合成抗原提示細胞としてのヒドロゲル粒子 |
| KR20250018496A (ko) | 2022-05-05 | 2025-02-06 | 슬링샷 바이오사이언시즈 인코포레이티드 | 혈액학을 위한 적혈구 모방체로서의 조작된 입자 및 이를 함유하는 조성물 |
| KR20250025383A (ko) | 2022-06-02 | 2025-02-21 | 슬링샷 바이오사이언시즈 인코포레이티드 | 아폽토시스 세포 모방체 |
| EP4608872A2 (en) | 2022-10-26 | 2025-09-03 | Slingshot Biosciences, Inc. | Size-tunable synthetic particles with tunable optical properties and methods for using the same for immune cell activation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3327117A (en) * | 1963-08-12 | 1967-06-20 | Ibm | Cancer cell detector using two wavelengths for comparison |
| US3315229A (en) * | 1963-12-31 | 1967-04-18 | Ibm | Blood cell recognizer |
| NL6702923A (enrdf_load_stackoverflow) * | 1966-04-06 | 1967-10-09 | ||
| US3699336A (en) * | 1969-08-15 | 1972-10-17 | Hycel Inc | Biological cell analyzing system |
| US3662176A (en) * | 1970-04-06 | 1972-05-09 | Bio Physics Systems Inc | Photo-optical particle analysis method and apparatus |
-
1972
- 1972-08-14 US US00280271A patent/US3822095A/en not_active Expired - Lifetime
-
1973
- 1973-07-16 GB GB3378673A patent/GB1425972A/en not_active Expired
- 1973-07-16 GB GB2153474A patent/GB1425973A/en not_active Expired
- 1973-08-13 JP JP48090805A patent/JPS4952489A/ja active Pending
- 1973-08-13 FR FR7329570A patent/FR2196708A5/fr not_active Expired
- 1973-08-13 NL NL7311146A patent/NL7311146A/xx unknown
- 1973-08-13 DE DE19732340843 patent/DE2340843A1/de active Pending
- 1973-08-14 CH CH1169773A patent/CH583021A5/xx not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2194368B1 (de) * | 2008-12-03 | 2019-07-17 | Grundfos Management A/S | Sensorsystem zum Erfassen und Spezifizieren von einzelnen Partikeln in einem Fluid |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7311146A (enrdf_load_stackoverflow) | 1974-02-18 |
| AU5838273A (en) | 1975-01-23 |
| JPS4952489A (enrdf_load_stackoverflow) | 1974-05-21 |
| GB1425973A (en) | 1976-02-25 |
| US3822095A (en) | 1974-07-02 |
| FR2196708A5 (enrdf_load_stackoverflow) | 1974-03-15 |
| CH583021A5 (enrdf_load_stackoverflow) | 1976-12-31 |
| GB1425972A (en) | 1976-02-25 |
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