DE2220906A1 - Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung - Google Patents

Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung

Info

Publication number
DE2220906A1
DE2220906A1 DE19722220906 DE2220906A DE2220906A1 DE 2220906 A1 DE2220906 A1 DE 2220906A1 DE 19722220906 DE19722220906 DE 19722220906 DE 2220906 A DE2220906 A DE 2220906A DE 2220906 A1 DE2220906 A1 DE 2220906A1
Authority
DE
Germany
Prior art keywords
formula
acid
imidazoline
group
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19722220906
Other languages
German (de)
English (en)
Inventor
Wolfgang Dr Hoefke
Herbert Dr Koeppe
Werner Dr Kummer
Helmut Dr Staehle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Priority to DE19722220906 priority Critical patent/DE2220906A1/de
Priority to AT343373A priority patent/AT322547B/de
Priority to CH83577A priority patent/CH601289A5/xx
Priority to CH590273A priority patent/CH594629A5/xx
Priority to NL7305823A priority patent/NL7305823A/xx
Priority to JP48048295A priority patent/JPS4941374A/ja
Priority to GB1996273A priority patent/GB1425846A/en
Priority to BE130563A priority patent/BE798885A/xx
Priority to NO1764/73A priority patent/NO136360C/no
Priority to ES414159A priority patent/ES414159A1/es
Priority to AU54943/73A priority patent/AU477612B2/en
Priority to FR7315569A priority patent/FR2183729B1/fr
Priority to US355412A priority patent/US3872121A/en
Publication of DE2220906A1 publication Critical patent/DE2220906A1/de
Priority to AT248374A priority patent/AT330768B/de
Priority to ES430119A priority patent/ES430119A1/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19722220906 1972-04-28 1972-04-28 Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung Pending DE2220906A1 (de)

Priority Applications (15)

Application Number Priority Date Filing Date Title
DE19722220906 DE2220906A1 (de) 1972-04-28 1972-04-28 Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
AT343373A AT322547B (de) 1972-04-28 1973-04-18 Verfahren zur herstellung von neuen 2-phenylaminoimidazolin-(2)-derivaten und deren säureadditionssalzen
CH83577A CH601289A5 (US08124317-20120228-C00018.png) 1972-04-28 1973-04-25
CH590273A CH594629A5 (US08124317-20120228-C00018.png) 1972-04-28 1973-04-25
NL7305823A NL7305823A (US08124317-20120228-C00018.png) 1972-04-28 1973-04-26
JP48048295A JPS4941374A (US08124317-20120228-C00018.png) 1972-04-28 1973-04-26
GB1996273A GB1425846A (en) 1972-04-28 1973-04-26 2-phenylamino-imidazolines-2- and the acid addition salts thereof processes for their preparation and pharmaceutical compositions containing the same
BE130563A BE798885A (fr) 1972-04-28 1973-04-27 Nouvelles 2-phenylamino-imidazolines-(2) substituees
NO1764/73A NO136360C (no) 1972-04-28 1973-04-27 Analogifremgangsm}te for fremstilling av nye terapeutisk aktive 2-fenylamino-imidazolin-(2)-er
ES414159A ES414159A1 (es) 1972-04-28 1973-04-27 Procedimiento para la preparacion de nuevos derivados de 2-fenilamino-imidazolina-(2).
AU54943/73A AU477612B2 (en) 1972-04-28 1973-04-27 2-phenylamino-imidazolines-(2) andthe acid addition salts thereof processes for their preparation and pharmaceutical compositions containing thesame
FR7315569A FR2183729B1 (US08124317-20120228-C00018.png) 1972-04-28 1973-04-27
US355412A US3872121A (en) 1972-04-28 1973-04-30 2-(Phenyl-amino-2-imidazolines and salts thereof
AT248374A AT330768B (de) 1972-04-28 1974-03-26 Verfahren zur herstellung von neuen 2-phenylaminoimidazolin- (2) -derivaten und deren saureadditionssalzen
ES430119A ES430119A1 (es) 1972-04-28 1974-09-17 Procedimiento para la preparacion de nuevos derivados de 2-fenilamino-imidazolina-(2).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722220906 DE2220906A1 (de) 1972-04-28 1972-04-28 Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
DE2220906A1 true DE2220906A1 (de) 1973-11-15

Family

ID=5843557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19722220906 Pending DE2220906A1 (de) 1972-04-28 1972-04-28 Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung

Country Status (11)

Country Link
US (1) US3872121A (US08124317-20120228-C00018.png)
JP (1) JPS4941374A (US08124317-20120228-C00018.png)
AT (1) AT322547B (US08124317-20120228-C00018.png)
BE (1) BE798885A (US08124317-20120228-C00018.png)
CH (2) CH601289A5 (US08124317-20120228-C00018.png)
DE (1) DE2220906A1 (US08124317-20120228-C00018.png)
ES (2) ES414159A1 (US08124317-20120228-C00018.png)
FR (1) FR2183729B1 (US08124317-20120228-C00018.png)
GB (1) GB1425846A (US08124317-20120228-C00018.png)
NL (1) NL7305823A (US08124317-20120228-C00018.png)
NO (1) NO136360C (US08124317-20120228-C00018.png)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007986A1 (de) * 1978-07-15 1980-02-20 C.H. Boehringer Sohn Neue substituierte 2-Phenylamino-imidazoline-(2), deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zur Herstellung derselben
EP1333028A1 (en) * 2002-01-31 2003-08-06 Boehringer Ingelheim Pharma GmbH & Co.KG 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
US6703409B2 (en) 2002-01-31 2004-03-09 Boehringer Ingelheim Pharma Gmbh & Co Kg 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4398028A (en) * 1977-01-14 1983-08-09 Sandoz Ltd. Bicyclic heterocyclic amino derivatives
JPS54151990A (en) * 1978-04-17 1979-11-29 Beiersdorf Ag Novel condensated nitrogenncontained heterocyclic compound and its manufacture
US4323570A (en) * 1978-11-15 1982-04-06 Beiersdorf Aktiengesellschaft Substituted aminopyrimidines
CA1175434A (en) * 1980-09-10 1984-10-02 Hoffmann-La Roche Limited ¬(2-phenylamino-1-imidazolidinyloxy)methyl| pyridine 1-oxide derivatives
US4517199A (en) * 1981-11-20 1985-05-14 Alcon Laboratories, Inc. Method for lowering intraocular pressure using phenylimino-imidazoles
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
US4515800A (en) * 1981-11-20 1985-05-07 Icilio Cavero Method of lowering intraocular pressure using phenylimino-imidazoles
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
US5258381A (en) * 1984-03-19 1993-11-02 The Rockefeller University 2-substituted-2-imidazolines
DE3527791A1 (de) * 1985-08-02 1987-02-12 Cassella Ag 2,5-dimethylpyrrolderivate, ihre herstellung und ihre verwendung
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
ES2076085B1 (es) * 1993-06-15 1997-03-01 Lilly Co Eli Antagonistas de angiotensina ii.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2719846A (en) * 1954-05-06 1955-10-04 Searle & Co 4[n-(beta-diethylaminoethyl) anilino]-pyrimidine and acid addition salts thereof
BE759048A (fr) * 1969-11-17 1971-05-17 Boehringer Sohn Ingelheim Nouvelles n-aminoalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
US3666767A (en) * 1970-01-28 1972-05-30 Warner Lambert Co 2-amino-1-(2-imidazolin-2-yl)-2-imidazolines

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007986A1 (de) * 1978-07-15 1980-02-20 C.H. Boehringer Sohn Neue substituierte 2-Phenylamino-imidazoline-(2), deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zur Herstellung derselben
EP1333028A1 (en) * 2002-01-31 2003-08-06 Boehringer Ingelheim Pharma GmbH & Co.KG 2'-Halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
WO2003064398A1 (en) * 2002-01-31 2003-08-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg 2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine derivatives and the use thereof for the treatment of urinary incontinence
US6703409B2 (en) 2002-01-31 2004-03-09 Boehringer Ingelheim Pharma Gmbh & Co Kg 2′-Halo-3′,5′-dialkoxyphen-1′-yl-imino-2-imidazolidine and the use thereof as a drug

Also Published As

Publication number Publication date
NO136360C (no) 1977-08-24
US3872121A (en) 1975-03-18
FR2183729B1 (US08124317-20120228-C00018.png) 1977-04-22
NL7305823A (US08124317-20120228-C00018.png) 1973-10-30
JPS4941374A (US08124317-20120228-C00018.png) 1974-04-18
ES414159A1 (es) 1976-02-01
AU5494373A (en) 1974-10-31
CH594629A5 (US08124317-20120228-C00018.png) 1978-01-13
AT322547B (de) 1975-05-26
ES430119A1 (es) 1976-10-16
BE798885A (fr) 1973-10-29
CH601289A5 (US08124317-20120228-C00018.png) 1978-07-14
FR2183729A1 (US08124317-20120228-C00018.png) 1973-12-21
NO136360B (US08124317-20120228-C00018.png) 1977-05-16
GB1425846A (en) 1976-02-18

Similar Documents

Publication Publication Date Title
EP0136658B1 (de) 1-Benzyl-aminoalkyl-pyrrolidinone und ihre Säureadditionssalze, Verfahren zu ihrer Herstellung und Arzneimittel
EP0035749B1 (de) Heterocyclische Verbindungen, ihre Herstellung und diese Verbindungen enthaltende Arzneimittel
DE68927254T2 (de) Arylpiperidin-Derivate
DE2220906A1 (de) Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
EP0005828B1 (de) Neue substituierte Phenylpiperazinderivate, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
EP0163260B1 (de) Neue substituierte Pyrrolidinone, Verfahren zu ihrer Herstellung und Arzneimittel
DE2847792C2 (US08124317-20120228-C00018.png)
WO1999054315A2 (de) Triazolone mit neuroprotektiver wirkung
DE2141818A1 (de) 2-phenylimino-imidazolidine, deren saeureadditionssalze und verfahren zu deren herstellung
EP0053767A1 (de) Tricyclische Cytosinderivate zur Verwendung in Arzneimitteln und Verfahren zu ihrer Herstellung
DE2633679A1 (de) 4,5-dihydro-2-niederalkoxycarbonylamino-4-phenylimidazole und derivate davon mit substituierter phenylgruppe
DE2143614A1 (de) 2-substituierte benzimidazole und verfahren zu deren herstellung
CH627452A5 (en) Process for the preparation of 2,6-disubstituted 2-phenyliminoimidazolidines and their acid addition salts
DE2523103A1 (de) Neue propargyl-2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DD151408A5 (de) Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate
EP0253084A2 (de) 1,3-Disubstituierte Imidazoliumsalze
EP0200947A1 (de) 1,3-Disubstituierte Imidazoliumsalze
DE2308883A1 (de) Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2518032A1 (de) 2-aminoimidazole, verfahren zu deren herstellung und dieselben enthaltendes mittel
DE3715763A1 (de) Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel
EP0280290B1 (de) Mittel mit antidepressiver Wirkung
EP0154721A1 (de) Neue Alkanolderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltendes Arzneimittel
EP0266532A1 (de) 1,3-Disubstituierte Imidazoliumsalze
DE2356005A1 (de) Neue 7-amino-imidazo eckige klammer auf 1,2-a eckige klammer zu pyrimidine, diese enthaltende arzneimittel sowie verfahren zu deren herstellung
DD216013A5 (de) Verfahren zur herstellung neuer ethendiamin- und guanidin-derivate

Legal Events

Date Code Title Description
OD Request for examination
OHN Withdrawal