DE2162900C2 - Steriles resorbierbares chirurgisches Nahtmaterial - Google Patents
Steriles resorbierbares chirurgisches NahtmaterialInfo
- Publication number
- DE2162900C2 DE2162900C2 DE2162900A DE2162900A DE2162900C2 DE 2162900 C2 DE2162900 C2 DE 2162900C2 DE 2162900 A DE2162900 A DE 2162900A DE 2162900 A DE2162900 A DE 2162900A DE 2162900 C2 DE2162900 C2 DE 2162900C2
- Authority
- DE
- Germany
- Prior art keywords
- copolymer
- yarn
- percent
- tensile strength
- lactide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229920001577 copolymer Polymers 0.000 claims description 65
- 238000001125 extrusion Methods 0.000 claims description 44
- 239000003356 suture material Substances 0.000 claims description 36
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 34
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims description 29
- 238000002513 implantation Methods 0.000 claims description 26
- 241001465754 Metazoa Species 0.000 claims description 12
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- TVRGPOFMYCMNRB-UHFFFAOYSA-N quinizarine green ss Chemical compound C1=CC(C)=CC=C1NC(C=1C(=O)C2=CC=CC=C2C(=O)C=11)=CC=C1NC1=CC=C(C)C=C1 TVRGPOFMYCMNRB-UHFFFAOYSA-N 0.000 claims description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 56
- 229910052757 nitrogen Inorganic materials 0.000 description 28
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Polymers OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 27
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 27
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 24
- 239000000203 mixture Substances 0.000 description 23
- 238000002844 melting Methods 0.000 description 20
- 230000008018 melting Effects 0.000 description 20
- 238000006243 chemical reaction Methods 0.000 description 16
- 238000006116 polymerization reaction Methods 0.000 description 15
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 14
- 238000009954 braiding Methods 0.000 description 14
- 239000000178 monomer Substances 0.000 description 14
- 239000003054 catalyst Substances 0.000 description 13
- 229920000642 polymer Polymers 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 239000001569 carbon dioxide Substances 0.000 description 12
- 229910002092 carbon dioxide Inorganic materials 0.000 description 12
- 239000007787 solid Substances 0.000 description 12
- 239000011521 glass Substances 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 10
- 238000003756 stirring Methods 0.000 description 10
- 206010052428 Wound Diseases 0.000 description 9
- 208000027418 Wounds and injury Diseases 0.000 description 9
- 239000007789 gas Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 238000010521 absorption reaction Methods 0.000 description 8
- 238000010438 heat treatment Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical group CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 7
- 239000011541 reaction mixture Substances 0.000 description 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 6
- 239000000975 dye Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 229920001296 polysiloxane Polymers 0.000 description 6
- BYEAHWXPCBROCE-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoropropan-2-ol Chemical compound FC(F)(F)C(O)C(F)(F)F BYEAHWXPCBROCE-UHFFFAOYSA-N 0.000 description 5
- 102000008186 Collagen Human genes 0.000 description 5
- 108010035532 Collagen Proteins 0.000 description 5
- 229920000954 Polyglycolide Polymers 0.000 description 5
- 241000700159 Rattus Species 0.000 description 5
- KYKAJFCTULSVSH-UHFFFAOYSA-N chloro(fluoro)methane Chemical compound F[C]Cl KYKAJFCTULSVSH-UHFFFAOYSA-N 0.000 description 5
- 229920001436 collagen Polymers 0.000 description 5
- JQZRVMZHTADUSY-UHFFFAOYSA-L di(octanoyloxy)tin Chemical compound [Sn+2].CCCCCCCC([O-])=O.CCCCCCCC([O-])=O JQZRVMZHTADUSY-UHFFFAOYSA-L 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 239000004576 sand Substances 0.000 description 5
- 229910001220 stainless steel Inorganic materials 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- 238000004804 winding Methods 0.000 description 5
- 239000000155 melt Substances 0.000 description 4
- 239000004633 polyglycolic acid Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 229920001519 homopolymer Polymers 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 238000001757 thermogravimetry curve Methods 0.000 description 3
- IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical compound [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 description 3
- AEMRFAOFKBGASW-UHFFFAOYSA-M Glycolate Chemical compound OCC([O-])=O AEMRFAOFKBGASW-UHFFFAOYSA-M 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 239000002729 catgut Substances 0.000 description 2
- 238000007334 copolymerization reaction Methods 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000004043 dyeing Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 238000004817 gas chromatography Methods 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 239000004753 textile Substances 0.000 description 2
- AXUYQDCVKHKQOW-UHFFFAOYSA-N 2-fluoropropan-2-ol Chemical compound CC(C)(O)F AXUYQDCVKHKQOW-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000282461 Canis lupus Species 0.000 description 1
- 241000122205 Chamaeleonidae Species 0.000 description 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 239000012768 molten material Substances 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- XULSCZPZVQIMFM-IPZQJPLYSA-N odevixibat Chemical compound C12=CC(SC)=C(OCC(=O)N[C@@H](C(=O)N[C@@H](CC)C(O)=O)C=3C=CC(O)=CC=3)C=C2S(=O)(=O)NC(CCCC)(CCCC)CN1C1=CC=CC=C1 XULSCZPZVQIMFM-IPZQJPLYSA-N 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 239000002685 polymerization catalyst Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
- A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
- D01F6/58—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products
- D01F6/62—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters
- D01F6/625—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from homopolycondensation products from polyesters derived from hydroxy-carboxylic acids, e.g. lactones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Materials Engineering (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Textile Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Polyesters Or Polycarbonates (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9955770A | 1970-12-18 | 1970-12-18 | |
| US19914371A | 1971-11-16 | 1971-11-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE2162900A1 DE2162900A1 (de) | 1972-06-29 |
| DE2162900C2 true DE2162900C2 (de) | 1985-03-28 |
Family
ID=26796220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2162900A Expired DE2162900C2 (de) | 1970-12-18 | 1971-12-17 | Steriles resorbierbares chirurgisches Nahtmaterial |
Country Status (15)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH656884A5 (de) * | 1983-08-26 | 1986-07-31 | Sandoz Ag | Polyolester, deren herstellung und verwendung. |
| US4750910A (en) * | 1986-01-22 | 1988-06-14 | Mitsui Toatsu Chemicals, Incorporated | Indigo blue-colored bioabsorbable surgical fibers and production process thereof |
| US5310599A (en) * | 1993-05-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Method for making polymers of alpha-hydroxy acids |
| US7378045B2 (en) | 2002-06-25 | 2008-05-27 | Ethicon, Inc. | Process for the formation of high strength bio-absorbable suture fibers |
| CN104294386A (zh) * | 2014-09-30 | 2015-01-21 | 张家港市金立纳米高弹材料有限公司 | 一种人造草丝的螺杆挤压装置 |
| CN104264254A (zh) * | 2014-09-30 | 2015-01-07 | 张家港市金立纳米高弹材料有限公司 | 人造草丝的熔融挤出装置 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD36499A (enrdf_load_stackoverflow) * | 1960-12-12 | |||
| FR1478694A (fr) * | 1965-04-20 | 1967-04-28 | Ethicon Inc | élément de suture absorbable et son procédé de fabrication |
| DE1642111A1 (de) * | 1965-04-20 | 1971-12-30 | Ethicon Inc | Chirurgisches Nahtmaterial und Verfahren zu seiner Herstellung |
| US3531561A (en) * | 1965-04-20 | 1970-09-29 | Ethicon Inc | Suture preparation |
-
1971
- 1971-11-29 IE IE1506/71A patent/IE35855B1/xx unknown
- 1971-12-13 AU AU36774/71A patent/AU470180B2/en not_active Expired
- 1971-12-14 CA CA130,099,A patent/CA950308A/en not_active Expired
- 1971-12-16 GB GB5856471A patent/GB1375008A/en not_active Expired
- 1971-12-17 IT IT32576/71A patent/IT954156B/it active
- 1971-12-17 ES ES398087A patent/ES398087A1/es not_active Expired
- 1971-12-17 SE SE7116217A patent/SE394593B/xx unknown
- 1971-12-17 IL IL38390A patent/IL38390A/xx unknown
- 1971-12-17 FI FI3601/71A patent/FI58436C/fi active
- 1971-12-17 NL NLAANVRAGE7117360,A patent/NL175140C/xx not_active IP Right Cessation
- 1971-12-17 DK DK621071A patent/DK152336C/da not_active IP Right Cessation
- 1971-12-17 AT AT1087271A patent/AT334546B/de not_active IP Right Cessation
- 1971-12-17 CH CH1847271A patent/CH588287A5/xx not_active IP Right Cessation
- 1971-12-17 DE DE2162900A patent/DE2162900C2/de not_active Expired
- 1971-12-20 BE BE776980A patent/BE776980A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT954156B (it) | 1973-08-30 |
| FI58436B (fi) | 1980-10-31 |
| NL175140C (nl) | 1984-10-01 |
| FI58436C (fi) | 1981-02-10 |
| IE35855L (en) | 1972-06-18 |
| DK152336B (da) | 1988-02-22 |
| CH588287A5 (enrdf_load_stackoverflow) | 1977-05-31 |
| SE394593B (sv) | 1977-07-04 |
| IL38390A0 (en) | 1972-02-29 |
| IL38390A (en) | 1974-06-30 |
| GB1375008A (enrdf_load_stackoverflow) | 1974-11-27 |
| IE35855B1 (en) | 1976-06-09 |
| AU470180B2 (en) | 1976-03-04 |
| ES398087A1 (es) | 1975-09-01 |
| CA950308A (en) | 1974-07-02 |
| BE776980A (fr) | 1972-06-20 |
| AU3677471A (en) | 1973-06-14 |
| DE2162900A1 (de) | 1972-06-29 |
| DK152336C (da) | 1988-07-25 |
| NL175140B (nl) | 1984-05-01 |
| AT334546B (de) | 1976-01-25 |
| ATA1087271A (de) | 1976-05-15 |
| NL7117360A (enrdf_load_stackoverflow) | 1972-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2257334C2 (de) | Verfahren zur Herstellung von Poly-[L(-)-lactid-coglycolid] | |
| US5217485A (en) | Polypropylene monofilament suture and process for its manufacture | |
| DE69528492T2 (de) | Medizinische Geräte, die Poly(p-dioxanone) mit hoher Eigenviskosität enthalten | |
| DE2025468C2 (de) | Verfahren und Vorrichtung zur Herstellung eines absorbierbaren Polyglycolsäurefadens | |
| DE69530363T2 (de) | Absorbierbare Polyetherestercarbonat-Blockcopolymere und daraus gefertigte chirurgische Artikel | |
| DE2700729C2 (de) | Synthetisches, absorbierbares chirurgisches Nahtmaterial und Verfahren zu seiner Herstellung | |
| DE69834375T2 (de) | Geflochtenes Nahtmaterial mit verbesserter Knotenfestigkeit | |
| US6063105A (en) | Medical devices fabricated from elastomeric alpha-olefins | |
| DE69408897T2 (de) | Absorbierbare Blockcopolymere und chirurgische Gegenstände daraus | |
| DE3640658C2 (de) | Kristallines p-Dioxanon/Glycolid Copolymeres und daraus hergestellte chirurgische Vorrichtungen | |
| DE60109112T2 (de) | Multifilamentgarne und Herstellungsverfahren | |
| DE1660181B2 (de) | Verfahren zur herstellung eines als chirurgisches nahtmaterial geeigneten polyglycolsaeurefadens | |
| DE2062604A1 (de) | Im Körper resorbierbares chirurgisches Material | |
| DE69027822T2 (de) | Wärmebehandlung von thermoplastischen Filamenten und Filamente | |
| DE1435614A1 (de) | Verfahren zur Herstellung von Kunstfaeden | |
| EP0585814B1 (en) | Suture fabricated from syndiotactic polypropylene and process for its manufacture | |
| EP0835895B1 (de) | Chirugisches Nahtmaterial aus Triblockterpolymer, seine Verwendung in der Chirurgie und Verfahren zur Herstellung | |
| DE3335588A1 (de) | (epsilon)-caprolacton und glykolid enthaltendes polymermaterial | |
| DE69417115T2 (de) | Verfahren zur Herstellung chirurgischen Nahtmaterials | |
| DE19641334A1 (de) | Triblockterpolymer, seine Verwendung für medizinische Produkte und Verfahren zur Herstellung | |
| DE2162900C2 (de) | Steriles resorbierbares chirurgisches Nahtmaterial | |
| JPH0496758A (ja) | 手術用縫合糸の製造法 | |
| JPS6130585B2 (enrdf_load_stackoverflow) | ||
| DE69521471T2 (de) | Absorbierbares Nahtmaterial | |
| DE1669373A1 (de) | Verfahren zum Schmelzspinnen von Fasern |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OD | Request for examination | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition |