DE2040999B2 - USE OF A CARBOHYDRATE - Google Patents

USE OF A CARBOHYDRATE

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Publication number
DE2040999B2
DE2040999B2 DE19702040999 DE2040999A DE2040999B2 DE 2040999 B2 DE2040999 B2 DE 2040999B2 DE 19702040999 DE19702040999 DE 19702040999 DE 2040999 A DE2040999 A DE 2040999A DE 2040999 B2 DE2040999 B2 DE 2040999B2
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Germany
Prior art keywords
xylitol
sugar
cariogenic
production
foods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19702040999
Other languages
German (de)
Other versions
DE2040999A1 (en
Inventor
Erika Dr. Basel Böhni (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2040999A1 publication Critical patent/DE2040999A1/en
Publication of DE2040999B2 publication Critical patent/DE2040999B2/en
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/42Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/14Organic oxygen compounds
    • A21D2/18Carbohydrates
    • A21D2/181Sugars or sugar alcohols
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/38Sucrose-free products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/33Artificial sweetening agents containing sugars or derivatives
    • A23L27/34Sugar alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/282Organic compounds, e.g. fats
    • A61K9/2826Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Description

Die Verwendung von Xylit als Zuckeraustauschstoff für Diabetiker bzw. in diätetischen Lebensmitteln, ist beispielsweise aus dem »Handbuch der Lebensmittelchemie«, L. Acker u.a., Bd. 5/1, 1967, S. 683, bekannt.The use of xylitol as a sugar substitute for diabetics or in dietary foods is for example from the "Handbuch der Lebensmittelchemie", L. Acker et al., Vol. 5/1, 1967, p. 683, known.

Es wurde nun festgestellt, daß Xylit, im Gegensatz JXL den üblicherweise für die menschliche Ernährung frerwendeten Zuckern, wie Saccharose, Glucose u. dgl., iiveder das Wachstum kariogener Bakterien fördert, doch durch kariogene Bakterien zu Säuren abgebaut Wird, die ihrerseits eine der wesentlichsten Ursachen (der Karies sind.It has now been found that xylitol, in contrast to JXL the sugars usually used for human nutrition, such as sucrose, glucose and the like, promotes the growth of cariogenic bacteria, but is broken down by cariogenic bacteria to acids, which in turn are one of the most essential Causes (which are tooth decay.

Die vorliegende Erfindung betrifft nun die Verwendung von Xylit zur Herstellung von zahnschonenden, nicht kariopcnen Lebens- und Genußmitteln, wobei man bei deren Herstellung zumindest teilweise Xylit verwendet. Eine bevorzugte Ausführungsform dieser Verwendung besteht darin, daß man den gesamten Zuckergehalt des Lebens- bzw. Genußmittels durch Xylit deckt, d. h., daß man den gesamten Anteil des üblicherweise verwendeten Zuckers (z. B. Saccharose) durch Xylit ersetzt.The present invention relates to the use of xylitol for the production of tooth-friendly, non-carious foods and luxury foods, where at least some of the xylitol is used in their production. A preferred embodiment this use consists in the fact that one has the total sugar content of the food or luxury food covered by xylitol, d. This means that the entire proportion of the sugar commonly used (e.g. sucrose) replaced by xylitol.

Die vorliegende Erfindung betrifft ferner die Verwendung von Xylit zur Herstellung von pharmazeutischen Tabletten und Dragees.The present invention also relates to the use of xylitol for the production of pharmaceuticals Tablets and coated tablets.

Als zuckerhaltige Lebens- und Genußmittcl sind zuckerhaltige Lebens- und Genußmittel in fester, halbfester oder flüssiger Form zu verstehen, z. B. Backwaren, wie Biskuits und Kuchen, Cremen, Speiseeis, zuckerhaltige Getränke, wie Sirupe und Fruchtsäfte.As sugary foods and beverages are To understand sugary foods and luxury foods in solid, semi-solid or liquid form, z. B. Bakery products, such as biscuits and cakes, creams, ice cream, sugary drinks such as syrups and fruit juices.

Insbesondere bezieht sich die vorliesende Erfindung auf die Verwendung von Xylit zur Herstellung von zahnschonenden, bzw. nicht kariogenen Süßwaren, d. h. Lebens- bzw. Genußmitteln mit hohem Zuckergehalt, wie beispielsweise Hart- und Weichkaramellen (Benbons), Fondant, Schaumzuckerwaren, Gummizuckerwaren, Lakritzv/aren, Dragees, pharmazeutischen Tabletten und Dragees, Pastillen, Fruchtpasten, Kaugummi, Krokant, Brausepulver, Marzipan, Persipan, Nugat, Schokoladen und Kakaoerzeugnisse, Speiseeis, Marmelade und Kunsthonig. Diese Verwendung besteht darin, daß man bei der Herstellung dieser Süßwaren an Stelle zumindest eines Teües des zur Herstellung üblicher Süßwaren verwendeten Zuckers Xylit verwendet. Auch hier wird vorzugsweise an Stelle der gesamten Menge des zur Herstellung üblicher Süßwaren verwendeten Zuckers Xylit verwendet. In particular, the present invention relates to the use of xylitol for the manufacture of Tooth-friendly or non-cariogenic sweets, d. H. Food and luxury foods with a high sugar content, such as hard and soft caramels (benbons), fondant, foamed sugar products, rubber candy products, Licorice v / aren, coated tablets, pharmaceutical tablets and coated tablets, lozenges, fruit pastes, Chewing gum, brittle, effervescent powder, marzipan, persipan, nougat, chocolate and cocoa products, Ice cream, jam and artificial honey. This use is that one in the manufacture this confectionery instead of at least a portion of that used for the production of conventional confectionery Sugar's xylitol is used. Here, too, is preferably used instead of the total amount of the for production Commonly used confectionery uses sugar xylitol.

Der Ersatz des üblichen Zuckers durch etwa gleiche Mengen Xylit ist deshalb möglich, weil Xylit etwa dieselbe Süßkraft wie üblicher Zucker aufweist.The replacement of the usual sugar with roughly equal amounts of xylitol is possible because xylitol is around has the same sweetness as normal sugar.

Eine besonders bevorzugte Ausführungsform der oben beschriebenen Verwendung zur Herstellung zahnschonender bzw. nicht kariogener Süßwaren, besteht in der Anwendung dieses Verfahrens auf die Her-A particularly preferred embodiment of the above-described use for producing tooth-friendly or non-cariogenic confectionery, consists in applying this process to the

PassagenPassages Streptococcus mutans (Streptococcus mutans ( ■) pH·*)■) pH *) 1. Stamm)1st trunk) -1,7-1.7 5151 PHPH ZuckerfreiSugar free pHpH NährmtdienNutrients -1,7-1.7 -2,8-2.8 7676 +0,3+0.3 %T% T +0,3+0.3 +0,5% Glucose+ 0.5% glucose -1,8-1.8 ! +0,5% Xylit! + 0.5% xylitol -1,9-1.9 7373 00 3030th 00 %T<% T < -1,8-1.8 %T% T -1,9-1.9 7676 -0,1-0.1 5353 -0,1-0.1 1.1. 66th -1,8-1.8 6060 -1,9-1.9 7070 -0,2-0.2 3636 -0,3-0.3 2.2. 66th -1,8-1.8 7676 -1,9-1.9 6767 -0,1-0.1 3636 -0,1-0.1 3*.3 *. 55 -1,8-1.8 4848 -1,9-1.9 7171 -0,1-0.1 4141 -0,1-0.1 4.4th 55 -1,8-1.8 3535 7?7? -0,1-0.1 3939 -0,1-0.1 5.5. 55 -1,8-1.8 4141 -i>-i> 7272 -0,1-0.1 3434 -0,1-0.1 6.6th 44th -1,9-1.9 3939 -1,8-1.8 3838 -0,1-0.1 2323 -0,1-0.1 7.7th 33 -1,8-1.8 3939 -2,6-2.6 4747 -0,1-0.1 3636 -0,1-0.1 8.8th. 44th -2,5-2.5 3838 -2,6-2.6 4747 -0,1-0.1 3535 -0,1-0.1 9.9. 44th -2,6-2.6 3838 -2,5-2.5 4848 -0,1-0.1 3737 -0,1-0.1 10.10. 55 -2,5-2.5 4242 -2,7-2.7 5454 -0,1-0.1 3232 -0,1-0.1 11.11th 44th -2,0-2.0 3232 -2,5-2.5 6060 00 3939 00 12.12th 44th -2,5-2.5 3737 -2,6-2.6 5959 -0,2-0.2 3636 00 13.13th 44th -2,6-2.6 3939 -2,6-2.6 5555 -0,1-0.1 3636 00 14.14th 44th -2,5-2.5 3838 -2,5-2.5 3535 -0,1-0.1 3838 -0,1-0.1 15.15th 44th -2,5-2.5 3838 - 5151 00 3636 -0,1-0.1 16.16. 44th 3232 -2,5-2.5 4747 - 3333 - 17.17th 44th -2,5-2.5 3636 5151 -0,1-0.1 3939 -0,1-0.1 18.18th 44th -2,0-2.0 3131 00 3636 -0,1-0.1 19.19th 55 3636 [2. Stamm)[2. Tribe) 3636 20.20th 55 3636 +0,4+0.4 +0,3+0.3 21.21. 44th 3535 +0,1+0.1 4040 +0,1+0.1 Streptococcus mutans 1Streptococcus mutans 1 00 6262 +0,1+0.1 1.1. 33 +0,1+0.1 6969 00 2.2. 55 +0,1+0.1 6767 +0,1+0.1 3.3. 55 +0,1+0.1 7373 +0,1+0.1 4.4th 66th +0,1+0.1 6262 +0,1+0.1 5.5. 66th DD. 6767 4-n ι4-n ι 6.6th 55 +0,1+0.1 +0J+ 0Y 7.7th 44th -0,1-0.1 7070 +0,1+0.1 R.R. 66th υυ 6060 υυ 9.9. 66th -ο,ι-ο, ι 7171 +0,1+0.1 10.10. 66th 00 6565 +0,1+0.1 11.11th 33 +0,2+0.2 6767 +0,1+0.1 12.12th 33 00 8383 +0,1+0.1 13.13th 33 00 5959 + 0,1+ 0.1 14.14th 22 00 6666 00 15.15th 33 00 6666 +0,1+0.1 16.16. 33 - 6262 - 17.17th 33 -0,1-0.1 6464 -0,1-0.1 18.18th 33 - 6666 - 19.19th 33 6363 20.20th 33 21.21. 55

*) Transmission (Uchtdurchlässigktit).*) Transmission (impermeability).

**) pH-Differenz pH vor Beimpfung und nlT nach Bebrütung während 24 Stunden bei 37° C.**) pH difference pH before inoculation and nIT after incubation for 24 hours at 37 ° C.

Versuch 1Attempt 1

Es wurde das Wachstum von zwei stark kariogenen Streptokokkenslämmen auf einem 0,5% Glucose enthaltenden Nährboden, iuf einem 0,5% Xylit enthaltenden Nährboden und auf einem zuckerfreien Nährboden in 21 Passagen bestimmt. Die Wachstums-The growth of two highly cariogenic streptococcal sponges on one containing 0.5% glucose was observed Culture medium, in a culture medium containing 0.5% xylitol and on a sugar-free culture medium determined in 21 passages. The growth

J) 20 40 9S3 J) 20 40 9 S3

3 43 4

intensität wurde an Hand ^ on Trübungsmessungen in Hefe, 4% Kleemehl, 3% Weizenkeimlinge und 3%Intensity was determined on the basis of turbidity measurements in yeast, 4% clover flour, 3% wheat seedlings and 3%

einem Nephelometer mit Filter 5300 A im prozentu- Mineralien und Vitamine.a nephelometer with filter 5300 A in percent - minerals and vitamins.

alen Vergleich zu einer unbeimpften Kontrolle be- Der obige Versuch 1 zeigt ferner, daß StreptokokkenThe above experiment 1 also shows that streptococci

stimmt. (Streptococcus mutans) auf einem Xylit enthaltendenit's correct. (Streptococcus mutans) on a xylitol containing

Der Abbau von Glucose bzw. Xylit wurde an Hand 5 Nährboden praktisch nicht wachsen und praktischThe breakdown of glucose or xylitol was practically not growing and practically on hand 5 nutrient medium

der Säurebildung durch elektrische pH-Messung vor keine pH-Änderung verursachen, im Gegensatz zuin contrast to the acid formation by electrical pH measurement before causing no pH change

und nach Bebrüten der Kulturmedien während einen) Glucose enthaltenden Nährboden. Andererseitsand after the culture media have been incubated during a nutrient medium containing glucose. on the other hand

24 Stunden bei 37 0C festgestellt. ist aus »Schweizerischer Monatsschrift für Zahnhcil-Determined at 37 ° C. for 24 hours. is from the »Swiss Monthly Journal for Dental Hygiene

Die Ergebnisse sind in der vorstehenden Tabelle künde«, Bd. 79, Februar 1969, S. 130, bekannt, daßThe results are shown in the table above, "Vol. 79, February 1969, p. 130, known that

zusammengestellt. io kariogene Streptokokken in vitro Sorbit vergären.compiled. io cariogenic streptococci ferment sorbitol in vitro.

Aus der obigen Tabelle ergibt sich, daß die beiden Dies zeigt, daß der Xylit dem Sorbit hinsichtlich seinerFrom the table above it can be seen that the two dies show that xylitol is compared to sorbitol in terms of its

Streptokokken-Stämme auf dem Glucose enthaltenden zahnschonenden Wirkung weit überlegen ist, was alsStreptococcus strains on the glucose-containing tooth-protecting effect is far superior to what is considered

Nährboden außerordentlich gut wachsen und diesen überraschend anzusehen ist, da ja angenommen werdenGrowing medium grow extremely well and this is surprising to look at, since yes are accepted

Nährboden in normalem Ausmaß vergären. Die dabei mußte, daß auch Xylit, welcher sich vom Sorbit nurFerment the nutrient medium to the normal extent. That had to include xylitol, which is only different from sorbitol

entstehende Säure erniedrigt den pH-Wert um etwa 15 durch das Fehlen einer Hydroxymethylgruppe unter-the resulting acid lowers the pH value by about 15 due to the lack of a hydroxymethyl group.

2 bis 2,5 Einheiten. scheidet, auch durch kariogene Streptokokken ver-2 to 2.5 units. differs, also caused by cariogenic streptococci

Demgegenüber wachsen die Streptokokken-Stämme goren werden würde.In contrast, the streptococcal strains growing would become fermented.

auf dem Xylit enthaltenden Nährboden wesentlich Die Erfindung wird an Hand folgender Beispieleessential on the xylitol-containing nutrient medium. The invention is illustrated by the following examples

weniger gut, und es tritt praktisch keine pH-Änderung noch näher erläuteit:less well, and there is practically no change in pH.

ein. 20 . .a. 20th .

Dies zeigt, daß die beiden stark kariogenen Strepto- BeispielThis shows that the two highly cariogenic strepto- example

kokken-Stämme Xylit praktisch nicht abzubauen Es werden Zuckerwürfel zum Süßen von KaffeeKokken-Strains Xylitol practically cannot be broken down. Sugar cubes are used to sweeten coffee

vermögen. oder Tee hergestellt, indem man Xylit mit etwa 2%capital. or tea made by adding xylitol with about 2%

Versuch 2 Wasser anfeuchtet, in Würfelform preßt (GewichtExperiment 2 Moistening the water, pressing it into a cube (weight

25 eines jeden Würfels etwa 3,3 g) und unter Ultrarot-25 of each cube about 3.3 g) and under ultrared

Es wurde an Ratten Normalfutter (ohne Zucker- bestrahlung trocknet,
zusatz), Normalfutter + 5% Saccharose, Normal- . .
futter + 10"^Saccharose, Normalfutter + 5% Xylit B e 1 s ρ 1 e 1 2
und Normalfutter + 10% Xylit verfüttert. Nach Man stellt Marmelade her, wobei man die üblicher-6wöchiger Versuchsdauer wurden die Zähne der 30 weise verwendete Saccharose durch die gleiche Menge Ratten auf Dentinschädigungen untersucht. Die Er- Xylit ersetzt. Eine derartige Marmelade (beispielsweise gebnisse sind in der folgenden Tabelle zusammen- Schwarzbeermartnelade oder Quittenmarmelade) entgestellt: hält pro 100 g etwa 25 g Xylit.
Rats were fed normal diet (without sugar irradiation, dried,
additive), normal feed + 5% sucrose, normal. .
feed + 10 "^ sucrose, normal feed + 5% xylitol B e 1 s ρ 1 e 1 2
and normal feed + 10% xylitol. After one makes jam, the usual 6-week test duration, the teeth of the 30 wise used sucrose were examined for dentin damage by the same amount of rats. The er-xylitol replaced. A jam of this type (for example, the results are shown in the following table - blackberry marmalade or quince jam): contains about 25 g of xylitol per 100 g.

DÜtt Ar1 der K^ 35 B e i S ρ i e 1 3DÜtt Ar 1 der K ^ 35 B ei S ρ ie 1 3

leichte Dentin- mittlere Dentin- ^s wird Schokolade hergestellt, wobei man an Stellelight dentin- medium dentin- ^ s is made of chocolate, with one in place

Schädigungen Schädigungen des üblicherweise verwendeten Zuckers Xylit ver-Damage Damage to the commonly used sugar xylitol

: wendet. Eine derartige zahnschonende Schokolade hat : turns. Such a tooth-friendly chocolate has

Normalfutter 2,07 0,07 beispielsweise einen Xylitgehalt von etwa 24%.Normal feed 2.07 0.07, for example, a xylitol content of around 24%.

Normalfutter 3,23 0,31 4° B e i s ρ i e 1 4Normal feed 3.23 0.31 4 ° B eis ρ ie 1 4

4- 5 /0 Saccharose Es wird em Brausepuiver folgender Zusammen-4- 5/0 sucrose It is em B rausepu i ver following cooperation

Normalfutter 4,36 1,0 setzung hergestellt:Normal chuck 4.36 1.0 settlement made:

+ 10% Saccharose .. .. -+ 10% sucrose .. .. -

Norrnalfutter 1,36 0,07 45 Sä ".".". \ \ \'. \ \ \ \'.'.'.'.'. \".".'.'. Λθ',0 gStandard feed 1.36 0.07 45 Sä ".". ". \ \ \ '. \ \ \ \'. '. '. '.'. \ ". ". '. '. Λθ ', 0 g

+ Vo Xvllt Natriumcarbonat 35,0 g+ Vo Xvllt sodium carbonate 35.0 g

Normalfutter 2,60 0,27 Oraneenaroma 1,5gNormal food 2.60 0.27 Orange flavor 1.5g

+ 10% Xylit Farbstoff 0,3 g+ 10% xylitol dye 0.3 g

Die obigen Zahlenwerte wurden ermittelt durch 50 Je 11 g dieses Pulvers werden in AluminiumsäckchenThe above numerical values were determined by 50 11 g of each of this powder in aluminum bags

quantitative Auszählungen von leichten und mittleren gefüllt, und die Säckchen werden versiegelt. Der Inhaltquantitative counts of light and medium filled, and the sachets are sealed. The content

Dentinläsionen und sind in Form von errechneten eines Säckchens reicht für die Bereitung eines GlasesDentine lesions and are calculated in the form of a sachet is enough for the preparation of a glass

Indices in der Tabelle angegeben. Sie zeigen, daß bei (etwa 100 bis 150 ml) Limonade.
Ernährung mit xylithaltiger Normalfutter-Diät die
Indices given in the table. They show that with (about 100 to 150 ml) lemonade.
Diet with normal feed diet containing xylitol the

Dentinschädigungen im allgemeinen nicht größer sind 55 U e 1 s ρ 1 e 1 .Dentin damage is generally not greater than 55 U e 1 s ρ 1 e 1.

als bei zuckerfreier Ernährung, während bei saccha- Es werden Biscuits hergestellt, wobei man den üb-than with a sugar-free diet, while with saccha- Biscuits are made using the usual

rosehaltiger Normalfutter-Diät Dcntinschädigungen licherwcise verwendeten Zucker durch Xylit ersetzt,normal feed diet containing rose din damage licherwcise sugar used is replaced by xylitol,

wesentlich häufiger auftreten. . · \ r occur much more frequently. . · \ R

Bei dem verwendeten Normalfutter handelt es sich β e 1 s ρ 1 e 1The normal feed used is β e 1 s ρ 1 e 1

um ein Tierfutter folgender Zusammensetzung: 45% 60 Es wird Kaugummi hergestellt, wobei man den üb-around an animal feed of the following composition: 45% 60 Chewing gum is produced, whereby the usual

Gerste, 18% Hafer, 10% Mais, 6% Fischmehl, 5% liclurweise verwendeten Zucker durch Xylit ersetzt.Barley, 18% oats, 10% maize, 6% fishmeal, 5% sugar, sometimes used, replaced by xylitol.

Claims (3)

Patentansprüche:Patent claims: 1. Verwendung von Xylit zur Herstellung von nicht kariogenen Lebens- und Genußmitteln.1. Use of xylitol for the production of non-cariogenic foods and luxury foods. 2. Verwendung von Xylit gcinäü Ansprach 1 zur Herstellung von Kaugummi.2. Use of xylitol gcinäü spoke 1 for making chewing gum. 3. Verwendung von Xylit zur Herstellung von pharmazeutischen Tabletten und Dragees.3. Use of xylitol for the production of pharmaceutical tablets and dragees. stellung von Bonbons und auf die Herstellung von Schokolade.production of candies and chocolate making. In den folgenden Versuchen wird gezeigt, daß XyLt im Gegensatz zu Glucose weder das Wachstum kariogener Bakterien fördert, noch durch kariogene Bakterien zu Säuren abgebaut wiiil. In the following experiments it is shown that XyLt, in contrast to glucose, neither promotes the growth of cariogenic bacteria nor is it broken down into acids by cariogenic bacteria.
DE19702040999 1969-08-22 1970-08-18 USE OF A CARBOHYDRATE Ceased DE2040999B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1276769A CH524319A (en) 1969-08-22 1969-08-22 Process for the production of sweetener-containing, tooth-friendly or non-cariogenic food and luxury foods

Publications (2)

Publication Number Publication Date
DE2040999A1 DE2040999A1 (en) 1971-03-04
DE2040999B2 true DE2040999B2 (en) 1976-02-19

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DE19702040999 Ceased DE2040999B2 (en) 1969-08-22 1970-08-18 USE OF A CARBOHYDRATE

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AR (1) AR192299A1 (en)
BE (1) BE755115A (en)
CH (1) CH524319A (en)
DE (1) DE2040999B2 (en)
DK (1) DK135696B (en)
FR (1) FR2059077A5 (en)
GB (1) GB1318424A (en)
HU (1) HU168232B (en)
IE (1) IE34476B1 (en)
IL (1) IL35118A (en)
IT (1) IT1033045B (en)
MY (1) MY7400035A (en)
NL (1) NL7011905A (en)
ZA (1) ZA705682B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932604A (en) * 1972-12-22 1976-01-13 Colgate-Palmolive Company Humectant sweetener
DE2703396A1 (en) * 1976-01-30 1977-08-04 Indiana University Foundation NON-CARIOGENIC FOOD AND METHOD OF MANUFACTURING THEREOF
CH623995A5 (en) * 1976-07-06 1981-07-15 Hoffmann La Roche Process for producing hard caramels
CH627629A5 (en) * 1978-04-05 1982-01-29 Xyrofin Ag Method for producing a covering layer on tabletted cores
US5817294A (en) * 1990-11-02 1998-10-06 Arnold; Michael J. Plaque adsorbent oral composition and method
US5804165A (en) * 1996-07-24 1998-09-08 Arnold; Michael J. Antiplaque oral composition
US7182968B2 (en) * 2001-01-11 2007-02-27 Fran Gare Composition containing xylitol and fiber

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2970058A (en) * 1959-12-04 1961-01-31 Ledoga Spa Process for preparing a fruit juice in powder form
US3296079A (en) * 1963-12-09 1967-01-03 Pfizer & Co C Products sweetened without sugar and characterized by freedom from aftertaste
US3278314A (en) * 1964-03-27 1966-10-11 Procter & Gamble Sweetened peanut food
DE1299990B (en) * 1965-03-20 1969-07-24 Maizena Werke Gmbh Deutsche Process for making durable fondant mass

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GB1318424A (en) 1973-05-31
IL35118A0 (en) 1971-02-25
IL35118A (en) 1974-05-16
BE755115A (en) 1971-02-22
IE34476B1 (en) 1975-05-14
FR2059077A5 (en) 1971-05-28
MY7400035A (en) 1974-12-31
DE2040999A1 (en) 1971-03-04
NL7011905A (en) 1971-02-24
HU168232B (en) 1976-03-28
IT1033045B (en) 1979-07-10
DK135696B (en) 1977-06-13
CH524319A (en) 1972-06-30
ZA705682B (en) 1971-04-28
AR192299A1 (en) 1973-02-14
IE34476L (en) 1971-02-22

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