DE202017005998U1 - Compact atomizer for the inhalation of volatile substances - Google Patents

Abstract

Compact atomizer for the inhalation of volatile active substances, consisting of a housing 1 1, 2 with a cavity 2 3 for drug absorption, wherein the underside of the housing has an adhesive layer 6 3 and the top of the housing has a perforated or permeable layer (membrane) 4 3.

Description

A compact nebulizer for the inhalation of volatile substances was developed. This consists of a housing 1 with a reservoir 2 , which serves as a drug storage, an impermeable adhesive layer 6 on the underside of the housing and a drug-permeable layer of membranartige material 4 on the top of the case. This nebulizer is applied to the skin near the nasal opening by means of the adhesive layer. He is barely noticeable. The membrane of the upper layer of the atomizer serves to escape the volatile substances during inhalation.

Volatile active substances are to be understood as meaning those which u. a. are of plant origin and cause minimal or no side effects, such as essential oils or, for example, cannabiol. These drugs are defined as remedies, preservatives and remedies, and do not raise any concerns from a physiological or therapeutic point of view and can be administered through the nose.

Small-dose, aromatic, aromatic oils are highly effective agents for calming and regulating mucosal and glandular activity and relieving pain. They can be used very well to normalize many physiological processes.

In order to achieve the desired effect, it is sufficient to inhale the least amounts of essential or aromatic oils, which are often used in aromatherapy or inhalation practice. Their effect is particularly effective when the diffusion of substances during respiration occurs by continuously delivering microdoses.

Against this background, this development has led to the development of a simple, compact nebulizer for the inhalation of volatile substances, which can be attached with an adhesive layer under the nose. In this way, its use prepares little discomfort, the breath is restricted as little as possible and effective delivery of the active ingredients to be inhaled is ensured.

To solve the above-mentioned object, therefore, a compact atomizer for inhalation of volatile active ingredients is offered, which consists of a housing with cavity 2 for receiving the drug reservoir 7 consists.

In the cavity 2 can in regions an open-pore foam material 7 and / or a fibrous material are introduced. The active ingredients contained therein show a very effective effect on the respiratory tract of humans due to the controlled diffusion occurring by a volatile dispersion. The reservoir can be filled in advance with the active substance or the filling of the volatile active substance takes place through the openings provided for this purpose or by immersion in a corresponding substance.

The nebulizer is intended for inhaling volatile agents through the nose. Its housing is made of a material approved for medical use and fulfills the following functions: The nebulizer must be able to be attached to the skin under the nostrils in the area of the outer surface without discomfort. It releases the contained substances without hindrance and only through the provided permeable layer or through a perforation.

Because of the cavity 2 is filled with an open-cell foam material and / or a fibrous material that allows diffusion of the liquid ingredients, no liquids or aerosols can escape from the compact atomizer while it is not used. The diffusion of the active ingredients takes place only when breathing as a result of the negative pressure through the openings.

The storage area with the foam material and / or fiber material introduced therein ensures a uniform release of the active substances as a function of the porosity of the material, ie. H. according to the pore size and the pore distance. The porous and fibrous material must be stable and neutral to all active substances with which it comes into contact. One advantage is that the open-celled foam material and / or fibrous material can be replaced after prolonged use and thus solves some problems that might occur without this possibility.

Thanks to the nature of the construction and the storage properties, the exiting active ingredients reach the nose when inhaled. The nebulizer is stuck to the skin and releases the active ingredient when inhaled.

In order for the active ingredient or substances to be delivered well, a correct attachment of the nebulizer under the nose is important. Usually, the two atomizers are adjusted and pressed by hand or fingers.

Due to its minimal size, the compact atomizer can be inconspicuous and aesthetically pleasing in public areas, while eating, talking and over long periods of time. The basic parameters of nasal breathing are not impaired, that is, no resistance to breathing is created by the nebulizers.

As a suitable, medically safe material for the atomizer z. As an elastic material, including silicone, are used.

The illustrations serve to clarify:

1 , Top view on two single atomizers under the nose

2 , Top view of the interconnected individual atomizers

3 , Section view of the developed atomizer housing

In the cavity 2 the atomizer becomes a store 7 or a filling of open cell foam material and / or fibrous material impregnated with volatile active ingredients.

The nebulizer is only slightly under the nose and its permeable upper layer leaves the volatile active ingredient free.

Cannabis-based drugs.

Anti-inflammatory and anti-asthmatic effect of cannabidiol or a CBD composition with essential oils.

Asthma is considered a chronic inflammatory disease because it has been found that the bronchi and their fine branches are constantly inflamed, even in seizure-free phases.

During a seizure, the inflammation increases and thereby aggravates the constriction caused by muscular contractions of the bronchial tissue. That cannabis is able to expand the bronchi is probably its most significant feature in relation to asthma treatment.

Asthma-related inflammation is generally considered to be an immune response to the presence of allergens, although the immune response has not been definitively demonstrated and there are likely to be large individual differences. Cannabis has been shown to reduce the constriction of the bronchi as effectively as salbutamol.

Bronchodilatory effect.

Several studies have shown that the administration of cannabis in various forms can significantly improve the constriction of the bronchi, both during an asthma attack and under normal conditions.

Analgesic and antispasmodic action

That cannabis is able to expand the bronchi is probably its most significant feature in relation to asthma treatment.

Although pain is not necessarily considered the primary symptom of an acute asthma attack, studies have shown that up to 76% of patients suffer from chest pain during a seizure. The known bronchodilatory and pain-relieving effects of certain cannabinoids suggest that they may be helpful in curbing asthmatic pain as they reduce pressure and constriction in the lungs and, at the same time, directly on the nociceptors (pain-sensitive nerve cells) themselves act.

Antibiotic effect

The cannabinoids THC, CBD and CBG have also been shown to have a potent germicidal effect on many common infectious pathogens (pathogens). One group of bacteria that is believed to be a potential cause of asthma is the genus Streptococcus, which includes S. pneumoniae and S. aureae. Several studies have shown that these can be controlled by the bactericidal effect of cannabinoids.

It is believed that the bronchodilatory effect of cannabis is mainly due to its anti-inflammatory properties.

In addition, it is believed that the ability of cannabis to reduce muscle spasm (involuntary contractions) plays an important role in controlling the bronchoconstriction during an asthma attack. Bronchi and bronchioles consist of smooth muscles that contract, contract and become inflamed during a seizure.

Mucolytic effect

Although the mucolytic effects of cannabis have not been established, it has been used for centuries in cough medicine.

LIST OF REFERENCE NUMBERS

1

casing

2

Storage

3

protective layer

4

membrane

5

protective layer

6

adhesive layer

7

Storage

8th

casing

9

connecting element

Claims (9)

Compact nebulizer for the inhalation of volatile substances, consisting of a housing 1 1 . 2 with a cavity 2 3 for drug absorption, wherein the underside of the housing an adhesive layer 6 3 and the top of the housing a perforated or permeable layer (membrane) 4 3 having. The compact nebulizer for the inhalation of volatile active substances according to claim 1 is characterized in that in the cavity 2 3 at least one memory 7 . 3 as open-pore foam material 7 . 3 or a fibrous material is arranged. The compact nebulizer for the inhalation of volatile active substances according to claim 2 is characterized in that the memory 7 . 3 can be exchanged. The compact atomizer for the inhalation of volatile substances is characterized by the fact that the cavity 2 3 in the case 1 1 . 2 is as a memory 7 . 3 provided for the absorption of liquid active substances. The compact nebulizer for the inhalation of volatile active substances according to claim 2 is characterized in that the complete device 1 from two separate parts 1 can exist. The compact nebulizer for inhalation of volatile active substances according to claim 5, characterized in that the atomizer from a unit 2 consists. The compact nebulizer for the inhalation of volatile active substances according to claim 6 is characterized in that the parts of the housing containing the active substance with a connecting element ( 9 ) 2 are connected The compact nebulizer for the inhalation of volatile substances is characterized by the fact that the active ingredients also contain marijuana. The compact atomizer for the inhalation of volatile substances is characterized by the fact that the outlet openings of the atomizer are directed to the nostrils.

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