DE2009515A1 - Artificial kidney dialysis membrane - Google Patents

Artificial kidney dialysis membrane

Info

Publication number
DE2009515A1
DE2009515A1 DE19702009515 DE2009515A DE2009515A1 DE 2009515 A1 DE2009515 A1 DE 2009515A1 DE 19702009515 DE19702009515 DE 19702009515 DE 2009515 A DE2009515 A DE 2009515A DE 2009515 A1 DE2009515 A1 DE 2009515A1
Authority
DE
Germany
Prior art keywords
dialysis membrane
artificial kidney
collagen
kidney dialysis
fabric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702009515
Other languages
German (de)
Inventor
Auf Nichtnennung Antrag
Original Assignee
Petrow, Michael, 8520 Erlangen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Petrow, Michael, 8520 Erlangen filed Critical Petrow, Michael, 8520 Erlangen
Priority to DE19702009515 priority Critical patent/DE2009515A1/en
Publication of DE2009515A1 publication Critical patent/DE2009515A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/74—Natural macromolecular material or derivatives thereof

Abstract

Dialysis membrane for an artificial kidney is a collagen sheet supported on a layer of fabric. Specif., the collagen is from comminuted horsehide. On drying at 60 degrees C after extrusion onto the fabric, the membrane decreases in thickness from 1000 to 15 mu as it loses water.

Description

Dialysemembran für künstliche Nieren 4 a Seit vielen Jahren sind künstliche Nieren in Gebrauch. Sie haben die Aufgabe, das Blut der Patienten von giftigen Stoffwechselprodukten zu befreien. Dies geschieht an einer Dialysemembran. Die bisher verwendeten Membranen bestehen aus Zellulose oder Kollagen. Kollagenfolien sind für den Austausch von Harnstoffen und Kreatinin vielfach besser geeignet, können aber nicht ohne weiteres verwendet werden, da sie eine zu geringe Festigkeit besitzen. Dialysis Membrane for Artificial Kidneys 4 a For many years are artificial kidneys in use. Their job is to draw the blood of patients from to rid toxic metabolic products. This is done on a dialysis membrane. The membranes used up to now consist of cellulose or collagen. Collagen foils are often better suited for the exchange of urea and creatinine but not readily used because they have too little strength.

Es ist zu beachten, daß die Folien oft nur 10 bis 30 y Dicke aufweisen.It should be noted that the foils are often only 10 to 30 y thick.

Erfindungsgemäß wird nun diese Kollagenfolie zunächst unter gegebenen Bedingungen hergestellt. Anschließend beschichtet man diese Folie mit einem dünnen Gewebe. Es ist darauf zu achten, daß das verwendete Gewebe möglichst gleichförmig ist, um eben eine gleichförmige Verstärkung der Kollagenfolie zu gewAhrleisten.According to the invention, this collagen foil is now initially given below Conditions established. This film is then coated with a thin one Tissue. It is important to ensure that the fabric used is as uniform as possible is to ensure a uniform reinforcement of the collagen foil.

Zur Herstellung der Kollagenfolie wird man vorzugsweise Rinderhaut in kleine Stücke zerschneiden und bei pil 3 quellen. Dann preßt man durch etwa 0,1 mm2 große Löcher. Die so entstehende Kollagenmasse hat einen Trockenstoffgehalt von etwa 10 %.Cow hide is preferably used to produce the collagen foil cut into small pieces and swell at pil 3. Then you press through about 0.1 mm2 holes. The resulting collagen mass has a dry matter content of about 10%.

Man wird sie dann vorzugsweise nochmals verdünnen auf etwa 0,5 % Trockenstoffgehalt. Diese Masse läßt sich dann leicht durch eine Schlitzdüse in Form einer dünnen Folie auspressen.They will then preferably be diluted again to about 0.5% dry matter content. This mass can then easily be passed through a slot nozzle in the form of a thin film to squeeze.

Die Folie kann zunächst eine Dicke von etwa 1 mm haben. Diese Folie, die zu über 99 % aus Wasser besteht, wird dann mit einem Gewebe verstärkt. Die Vereinigung beider Schichten erfolgt ohne Schwierigkeiten, da eben die Kollagenfolie infolge des hohen Wassergehaltes das Vers tärkungs gewebe zunächst ziemlich fest an sich bindet.The film can initially have a thickness of about 1 mm. This slide, which consists of over 99% water, is then reinforced with a fabric. The Union both layers takes place without difficulty, as the collagen foil as a result Due to the high water content, the reinforcement fabric is initially quite solid binds.

Anschließend trocknet man bei etwa 600C. Dabei verliert die Kollagenfolie erhebliche Mengen Wasser, wodurch ihre Dicke von ursprünglich 1000 cm auf z.B. 15 y zurückgeht.Then it is dried at about 600C. The collagen foil is lost in the process considerable amounts of water, reducing its thickness from originally 1000 cm to e.g. 15 y is decreasing.

Nach dem Trocknen ist der Verbund beider Schichten ebenfalls noch fest.After drying, the bond between the two layers is still there fixed.

Claims (1)

PatentanspruchClaim Dialysemembran,bestehend aus einer Kollagenfolie, die auf einer Gewebe-Stützschicht ruht.Dialysis membrane, consisting of a collagen foil, which is placed on a tissue support layer rests.
DE19702009515 1970-02-28 1970-02-28 Artificial kidney dialysis membrane Pending DE2009515A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19702009515 DE2009515A1 (en) 1970-02-28 1970-02-28 Artificial kidney dialysis membrane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702009515 DE2009515A1 (en) 1970-02-28 1970-02-28 Artificial kidney dialysis membrane

Publications (1)

Publication Number Publication Date
DE2009515A1 true DE2009515A1 (en) 1971-09-16

Family

ID=5763693

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702009515 Pending DE2009515A1 (en) 1970-02-28 1970-02-28 Artificial kidney dialysis membrane

Country Status (1)

Country Link
DE (1) DE2009515A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0085166A1 (en) * 1981-12-30 1983-08-10 New York Blood Center, Inc. A filter and a process for the preparation thereof
US4640778A (en) * 1981-12-30 1987-02-03 New York Blood Center, Inc. Fibrin gel-containing filter

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0085166A1 (en) * 1981-12-30 1983-08-10 New York Blood Center, Inc. A filter and a process for the preparation thereof
EP0187894A1 (en) * 1981-12-30 1986-07-23 New York Blood Center, Inc. A size selective catalyst comprising a fibrin gel
US4640778A (en) * 1981-12-30 1987-02-03 New York Blood Center, Inc. Fibrin gel-containing filter

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