DE19905160A1 - High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy - Google Patents

High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy

Info

Publication number
DE19905160A1
DE19905160A1 DE19905160A DE19905160A DE19905160A1 DE 19905160 A1 DE19905160 A1 DE 19905160A1 DE 19905160 A DE19905160 A DE 19905160A DE 19905160 A DE19905160 A DE 19905160A DE 19905160 A1 DE19905160 A1 DE 19905160A1
Authority
DE
Germany
Prior art keywords
prevent
allergens
epitopy
substance
changing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19905160A
Other languages
German (de)
Inventor
Gerrit Hoehn
Roland Meyer-Pittroff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bluemelhuber Gerrit Dipl-Ing 85084 Reichertsho
MEYER-PITTROFF, ROLAND, PROF. DR.-ING., 85354 FREI
Original Assignee
MEYER PITTROFF ROLAND
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEYER PITTROFF ROLAND filed Critical MEYER PITTROFF ROLAND
Priority to DE19905160A priority Critical patent/DE19905160A1/en
Publication of DE19905160A1 publication Critical patent/DE19905160A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C3/00—Preservation of milk or milk preparations
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/30—Physical treatment, e.g. electrical or magnetic means, wave energy or irradiation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C2210/00—Physical treatment of dairy products
    • A23C2210/15—High pressure treatment

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Substances containing allergens are subjected to pressures of 200-9000 bar to prevent or reduce the triggering of allergies in organisms.

Description

Allergien werden durch Allergene ausgelöst. Allergene sind Stoffe, die, wenn sie in den Organismus gelangen, von dem Immunsystem des Organismus als körperfremde Substanzen erkannt und durch eine übersteigerte Immunantwort bekämpft werden. Das Erkennen von Allergenen geschieht über deren Oberflächenstruktur, die sogenannten Epitope.Allergies are triggered by allergens. Allergens are substances that, when in get to the organism from the immune system of the organism Foreign substances recognized and by an excessive immune response be fought. Allergens are recognized via their Surface structure, the so-called epitopes.

Das körpereigene Immunsystem reagiert auf diese Epitope mit einer übersteigerten Immunaktion. Dies kann in harmlosen Fällen zu Hautausschlägen oder Rötungen der Schleimhäute führen, in besonders schweren Fällen (anaphylaktischer Schock) zu Asthmaanfällen, Atembeschwerden und zum Tode.The body's immune system reacts to these epitopes with an exaggerated one Immune action. In harmless cases, this can lead to rashes or redness of the mucous membranes, in particularly severe cases (anaphylactic shock) to asthma attacks, difficulty breathing and death.

Das erfindungsgemäße Verfahren verändert die Epitope in ihrer Struktur, so daß sie vom Immunsystem nicht mehr als körperfremd erkannt werden und so keine Immunreaktion ausgelöst wird. Bei dem erfindungsgemäßen Verfahren werden Allergene Drücken zwischen 200 und 9000 bar ausgesetzt, wobei die Druckhaltezeit zwischen 1 sec und 2 h liegt. Diese Behandlung wird einmal durchgeführt oder mehrfach wiederholt. Während der Druckhaltezeit wird das Allergen mit Temperaturen zwischen -25°C und 150°C beaufschlagt. Durch diese Behandlung werden die Epitope der Allergene irreversibel verändert, was dazu führt, daß sie vom Immunsystem nicht mehr als körperfremd identifiziert werden.The inventive method changes the structure of the epitopes so that they are no longer recognized by the immune system as foreign and therefore none Immune response is triggered. In the method according to the invention Allergens exposed to pressures between 200 and 9000 bar, the pressure holding time is between 1 sec and 2 h. This treatment is carried out once or repeated several times. The allergen is released during the pressure maintenance period Temperatures between -25 ° C and 150 ° C applied. Through this treatment the allergens' epitopes are irreversibly changed, which leads to them being Immune system can no longer be identified as foreign to the body.

Insbesondere in der Nahrungsmittelindustrie kann das erfindungsgemäße Verfahren angewendet werden. In den letzten Jahren nahmen die Lebensmittelallergien deutlich zu. Einige Lebensmittel stehen im Verdacht, überproportional oft Lebensmittelallergien auszulösen. Hierzu zählen Milchprodukte, Nüsse und Nussprodukte sowie einige Gewürze. Diese Lebensmittel können mit dem erfindungsgemäßen Verfahren derart verändert werden, daß eine Allergiereaktion ausgeschlossen werden kann.The method according to the invention can be used in particular in the food industry be applied. Food allergies have increased in recent years clearly too. Some foods are suspected, disproportionately often Trigger food allergies. These include dairy products, nuts and Nut products as well as some spices. These foods can with the The inventive method can be changed so that an allergy reaction can be excluded.

Claims (6)

1. Verfahren, dadurch gekennzeichnet, daß Allergene enthaltende Stoffe mit Drücken zwischen 200 und 9000 bar beaufschlagt werden, um das Auslösen von Allergien in Organismen zu verhindern oder zu verringern.1. The method, characterized in that substances containing allergens are subjected to pressures between 200 and 9000 bar in order to prevent or reduce the triggering of allergies in organisms. 2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß Druckhaltezeiten von 1 sec bis 2 h eingehalten werden.2. The method according to claim 1, characterized in that pressure holding times of 1 sec to 2 h are observed. 3. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Druckbeaufschlagung einmal durchgeführt wird.3. The method according to claim 1, characterized in that the Pressurization is performed once. 4. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Druckbeaufschlagung bis zu zehnmal durchgeführt wird.4. The method according to claim 1, characterized in that the Pressurization is carried out up to ten times. 5. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Allergene während der Druckbeaufschlagung Temperaturen von -25°C bis 150°C ausgesetzt werden.5. The method according to claim 1, characterized in that the allergens during exposed to temperatures from -25 ° C to 150 ° C become. 6. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß es sich bei den Allergenen enthaltenden Stoffen um Lebensmittel handelt.6. The method according to claim 1, characterized in that it is in the Allergens containing substances are food.
DE19905160A 1999-02-08 1999-02-08 High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy Withdrawn DE19905160A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19905160A DE19905160A1 (en) 1999-02-08 1999-02-08 High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19905160A DE19905160A1 (en) 1999-02-08 1999-02-08 High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy

Publications (1)

Publication Number Publication Date
DE19905160A1 true DE19905160A1 (en) 2000-09-21

Family

ID=7896839

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19905160A Withdrawn DE19905160A1 (en) 1999-02-08 1999-02-08 High pressure treatment of substance, especially food, containing allergens, is used to prevent or reduce allergic reactions by changing epitopy

Country Status (1)

Country Link
DE (1) DE19905160A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004031275A1 (en) * 2003-09-29 2005-04-21 Roland Meyer-Pittroff Medicament for specific immunotherapy, especially for combating food allergy, comprising material, preferably foodstuff, containing allergen subjected to antiallergenic pretreatment, preferably using high pressure
WO2005067731A1 (en) * 2004-01-20 2005-07-28 Technion Research & Development Foundation Ltd. Method and apparatus for reducing allergenic activity
WO2013113908A1 (en) * 2012-02-02 2013-08-08 Societe Financiere Cormouls Houles Method for preparing a hypoallergenic food

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004031275A1 (en) * 2003-09-29 2005-04-21 Roland Meyer-Pittroff Medicament for specific immunotherapy, especially for combating food allergy, comprising material, preferably foodstuff, containing allergen subjected to antiallergenic pretreatment, preferably using high pressure
WO2005067731A1 (en) * 2004-01-20 2005-07-28 Technion Research & Development Foundation Ltd. Method and apparatus for reducing allergenic activity
WO2013113908A1 (en) * 2012-02-02 2013-08-08 Societe Financiere Cormouls Houles Method for preparing a hypoallergenic food
FR2986401A1 (en) * 2012-02-02 2013-08-09 Financ Cormouls Houles Soc PROCESS FOR PREPARING A HYPOALLERGENIC FOOD

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Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: BLüMELHUBER, GERRIT, DIPL.-ING., 85084 REICHERTSHO

Owner name: MEYER-PITTROFF, ROLAND, PROF. DR.-ING., 85354 FREI

8139 Disposal/non-payment of the annual fee