DE19882066T1 - Reversibles stöchiometrisches Verfahren zum Konjugieren von Biomolekülen - Google Patents
Reversibles stöchiometrisches Verfahren zum Konjugieren von BiomolekülenInfo
- Publication number
- DE19882066T1 DE19882066T1 DE19882066T DE19882066T DE19882066T1 DE 19882066 T1 DE19882066 T1 DE 19882066T1 DE 19882066 T DE19882066 T DE 19882066T DE 19882066 T DE19882066 T DE 19882066T DE 19882066 T1 DE19882066 T1 DE 19882066T1
- Authority
- DE
- Germany
- Prior art keywords
- reversible
- stoichiometric method
- conjugating biomolecules
- conjugating
- biomolecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3716597P | 1997-02-04 | 1997-02-04 | |
| PCT/US1998/002007 WO1998033808A2 (en) | 1997-02-04 | 1998-02-04 | A reversible stoichiometric process for conjugating biomolecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19882066T1 true DE19882066T1 (de) | 2000-01-05 |
Family
ID=21892797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19882066T Withdrawn DE19882066T1 (de) | 1997-02-04 | 1998-02-04 | Reversibles stöchiometrisches Verfahren zum Konjugieren von Biomolekülen |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1000081A2 (no) |
| JP (1) | JP2001526776A (no) |
| AU (1) | AU748806B2 (no) |
| CA (1) | CA2284463A1 (no) |
| DE (1) | DE19882066T1 (no) |
| NO (1) | NO993746L (no) |
| WO (1) | WO1998033808A2 (no) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6225061B1 (en) | 1999-03-10 | 2001-05-01 | Sequenom, Inc. | Systems and methods for performing reactions in an unsealed environment |
| US20020009394A1 (en) | 1999-04-02 | 2002-01-24 | Hubert Koster | Automated process line |
| US7917301B1 (en) | 2000-09-19 | 2011-03-29 | Sequenom, Inc. | Method and device for identifying a biological sample |
| US20020155587A1 (en) | 2001-04-20 | 2002-10-24 | Sequenom, Inc. | System and method for testing a biological sample |
| CA2453434C (en) * | 2001-07-16 | 2009-04-14 | Hk Pharmaceuticals, Inc. | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions |
| US20060051879A9 (en) * | 2003-01-16 | 2006-03-09 | Hubert Koster | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions |
| US9394565B2 (en) | 2003-09-05 | 2016-07-19 | Agena Bioscience, Inc. | Allele-specific sequence variation analysis |
| US9249456B2 (en) | 2004-03-26 | 2016-02-02 | Agena Bioscience, Inc. | Base specific cleavage of methylation-specific amplification products in combination with mass analysis |
| KR101430627B1 (ko) | 2008-05-13 | 2014-08-14 | 유니버시티 오브 캔사스 | 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법 |
| WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
| WO2019081680A1 (en) * | 2017-10-25 | 2019-05-02 | Institut Pasteur | NUCLEIC ACID IMMOBILIZATION USING AN ENZYMATIC HISTIDINE LABEL MIMETIC FOR DIAGNOSTIC APPLICATIONS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985004674A1 (en) * | 1984-04-05 | 1985-10-24 | Life Technologies, Inc. | Immobilization of nucleic acids |
| DE3644346A1 (de) * | 1986-12-19 | 1987-05-21 | Saeulentechnik Dr Ing Herbert | Matrixgebundene kronenetherliganden als trennmaterial in der affinitaetschromatographie von nukleinsaeuren |
| CA1335721C (en) * | 1987-12-24 | 1995-05-30 | Patrick E. Guire | Biomolecule attached to a solid surface by means of a spacer and methods of attaching biomolecules to surfaces |
| WO1990001564A1 (en) * | 1988-08-09 | 1990-02-22 | Microprobe Corporation | Methods for multiple target analyses through nucleic acid hybridization |
| US5410068A (en) * | 1989-10-23 | 1995-04-25 | Perseptive Biosystems, Inc. | Succinimidyl trityl compounds and a process for preparing same |
| US5582981A (en) * | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
| US5547835A (en) * | 1993-01-07 | 1996-08-20 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
| EP0937096B1 (en) * | 1996-11-06 | 2004-02-04 | Sequenom, Inc. | Method of mass spectrometry analysis |
-
1998
- 1998-02-04 CA CA002284463A patent/CA2284463A1/en not_active Abandoned
- 1998-02-04 WO PCT/US1998/002007 patent/WO1998033808A2/en not_active Application Discontinuation
- 1998-02-04 AU AU61416/98A patent/AU748806B2/en not_active Ceased
- 1998-02-04 DE DE19882066T patent/DE19882066T1/de not_active Withdrawn
- 1998-02-04 EP EP98906096A patent/EP1000081A2/en not_active Withdrawn
- 1998-02-04 JP JP53319598A patent/JP2001526776A/ja not_active Ceased
-
1999
- 1999-08-03 NO NO993746A patent/NO993746L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001526776A (ja) | 2001-12-18 |
| WO1998033808A3 (en) | 1999-02-25 |
| AU6141698A (en) | 1998-08-25 |
| CA2284463A1 (en) | 1998-08-06 |
| NO993746L (no) | 1999-10-01 |
| EP1000081A2 (en) | 2000-05-17 |
| WO1998033808A2 (en) | 1998-08-06 |
| AU748806B2 (en) | 2002-06-13 |
| NO993746D0 (no) | 1999-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8127 | New person/name/address of the applicant |
Owner name: SEQUENOM, INC., SAN DIEGO, CALIF., US |
|
| 8607 | Notification of search results after publication | ||
| 8139 | Disposal/non-payment of the annual fee |