DE19882066T1 - Reversible stoichiometric method for conjugating biomolecules - Google Patents

Reversible stoichiometric method for conjugating biomolecules

Info

Publication number
DE19882066T1
DE19882066T1 DE19882066T DE19882066T DE19882066T1 DE 19882066 T1 DE19882066 T1 DE 19882066T1 DE 19882066 T DE19882066 T DE 19882066T DE 19882066 T DE19882066 T DE 19882066T DE 19882066 T1 DE19882066 T1 DE 19882066T1
Authority
DE
Germany
Prior art keywords
reversible
stoichiometric method
conjugating biomolecules
conjugating
biomolecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19882066T
Other languages
German (de)
Inventor
Andreas Ruppert
Hubert Koester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequenom Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE19882066T1 publication Critical patent/DE19882066T1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE19882066T 1997-02-04 1998-02-04 Reversible stoichiometric method for conjugating biomolecules Withdrawn DE19882066T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3716597P 1997-02-04 1997-02-04
PCT/US1998/002007 WO1998033808A2 (en) 1997-02-04 1998-02-04 A reversible stoichiometric process for conjugating biomolecules

Publications (1)

Publication Number Publication Date
DE19882066T1 true DE19882066T1 (en) 2000-01-05

Family

ID=21892797

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19882066T Withdrawn DE19882066T1 (en) 1997-02-04 1998-02-04 Reversible stoichiometric method for conjugating biomolecules

Country Status (7)

Country Link
EP (1) EP1000081A2 (en)
JP (1) JP2001526776A (en)
AU (1) AU748806B2 (en)
CA (1) CA2284463A1 (en)
DE (1) DE19882066T1 (en)
NO (1) NO993746L (en)
WO (1) WO1998033808A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225061B1 (en) 1999-03-10 2001-05-01 Sequenom, Inc. Systems and methods for performing reactions in an unsealed environment
US20020009394A1 (en) 1999-04-02 2002-01-24 Hubert Koster Automated process line
US7917301B1 (en) 2000-09-19 2011-03-29 Sequenom, Inc. Method and device for identifying a biological sample
US20020155587A1 (en) 2001-04-20 2002-10-24 Sequenom, Inc. System and method for testing a biological sample
EP2053406A3 (en) * 2001-07-16 2009-06-24 caprotec bioanalytics GmbH Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
CA2658334C (en) 2003-01-16 2012-07-10 Caprotec Bioanalytics Gmbh Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
WO2005024068A2 (en) 2003-09-05 2005-03-17 Sequenom, Inc. Allele-specific sequence variation analysis
WO2005098050A2 (en) 2004-03-26 2005-10-20 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
KR20140001257A (en) 2008-05-13 2014-01-06 유니버시티 오브 캔사스 Metal abstraction peptide(map) tag and associated methods
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2019081680A1 (en) * 2017-10-25 2019-05-02 Institut Pasteur Immobilization of nucleic acids using an enzymatic his-tag mimic for diagnostic applications

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501746A (en) * 1984-04-05 1986-08-21 ライフ　テクノロジ−ズ，インコ−ポレイテツド Nucleic acid immobilization method
DE3644346A1 (en) * 1986-12-19 1987-05-21 Saeulentechnik Dr Ing Herbert Matrix-bound crown ether ligands as separating material in the affinity chromatography of nucleic acids
CA1335721C (en) * 1987-12-24 1995-05-30 Patrick E. Guire Biomolecule attached to a solid surface by means of a spacer and methods of attaching biomolecules to surfaces
WO1990001564A1 (en) * 1988-08-09 1990-02-22 Microprobe Corporation Methods for multiple target analyses through nucleic acid hybridization
US5410068A (en) * 1989-10-23 1995-04-25 Perseptive Biosystems, Inc. Succinimidyl trityl compounds and a process for preparing same
US5582981A (en) * 1991-08-14 1996-12-10 Gilead Sciences, Inc. Method for identifying an oligonucleotide aptamer specific for a target
US5547835A (en) * 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
EP1460083B1 (en) * 1996-11-06 2006-01-18 Sequenom, Inc. Analysing method and apparatus

Also Published As

Publication number Publication date
NO993746D0 (en) 1999-08-03
JP2001526776A (en) 2001-12-18
WO1998033808A3 (en) 1999-02-25
CA2284463A1 (en) 1998-08-06
AU748806B2 (en) 2002-06-13
NO993746L (en) 1999-10-01
AU6141698A (en) 1998-08-25
EP1000081A2 (en) 2000-05-17
WO1998033808A2 (en) 1998-08-06

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8127 New person/name/address of the applicant

Owner name: SEQUENOM, INC., SAN DIEGO, CALIF., US

8607 Notification of search results after publication
8139 Disposal/non-payment of the annual fee