DE1791012A1 - Two-chamber injector - Google Patents

Description

Dr.-Ing. Herb0rtMo $$ r

75 Karlsruhe, Ettli * g * ntm69l§ ^

Applicant: PfIier Gebfl., Karl »rests Two caraer IaJtk tor

The invention relates to a Zveikasaier injector, particularly for veterinary veekeys, with an "injector designed as a piston preprite" which holds a first camera for a substance to be mixed.

In human and veterinary medicine, various devices are required for instillation and injection of τοη drugs, Pie development slides on for the applying Arit die Prepare for instillation or injection there as well as possible SU Ytreinfaehtn, where carrion used armelalttel only before use from svsi or several starting substances by mixing are produced on Is are therefore in different forms of execution Immediate injection spirits known, velobt iwei auf *

109843/0521 " ² "

BATH ORIGINAL

show close-ups, in which the exits to be bischenden are sub β tanz eu. When Gebrauohsftrtigaaohen a Partition between these chambers opened, so d & 3 ready for harvest Content is created »Such well-known Zwtikaaraer-InjektionsßpritKeu however, are expensive to manufacture or have difficulties in practical use, the a wider spread la ways are · especially in the Veterinary products are easy to manufacture and use Devices * ur instillation and injection desired that should be able to be manufactured as a mass-produced item without significant expense

For the treatment of local diseases in animals, especially in cow udders, preparations are used in which the active ingredients are dispersed in mineral or plant-based bases The udder can be injected into the udder. Large amounts of the mineral or vegetable oil and old aluestearate yerdiocte carrier substances are injected, which results in an increased release and absorption of the active agent and possibly a fitter body effect Yehikel are limiting. "Ow are also considered" £ s Dafi I "Yieis" cases in the udder itself is not enough liquid Ur disentanglement of the active ingredients aue the fatty Grundsubft ** · * "sur is available.

109843/0521

BAB ORfGfNAL

For this reason, the Kubtreitungsformen could be in general and vegetable oil articles do not prevail to a great extent · KIn A large part of the udder inflammation is therefore caused by aqueous drug solutions treated. Such preparations are marketable in the form of the usual ampoules or ampoule bottles an ampoule bottle contains the active ingredients in dry form. In another ampoule bottle or ampoule the solvent is included, so that gate start the treatment first with a syringe both substances need to be raised, which then as a resultant Solution form the injectable drug. The use of injection syringes of this type is permitted when using several tubes awkward, especially under "Jerlickoichtl ^ ung the upper ^ etlii ^ mn ^ en, under which veterinary love is carried out Need to become.

It seems obvious from the current state of affairs, too the aqueous to be used for veterinary application Solutions immediately gate the start of treatment in a ready-to-use To manufacture two-component injection syringes, like this already in the HuraanmediBin, for example for the Injection of chloramphenicol, is known. The gate acquaintances However, fuel constructions are for veterinary use not suitable as a mass-produced item.

The invention is based on the task of creating a two-cylinder injector, especially for veterinary purposes, to create dtr as a mass-produced article cheaply and a special one allows easy handling. Starting point for the innovation

109843/0521

ÖBMMNAU

Injector formed in Ala piston apritae which tint trttt Kantr fu * tint in sisehtadt Subtttni uptiat. Rennieichnende dtr invention is it ro athtB, deß tint ivtllt Kasatr for admission tlntr further eu aiaohtfidtn Snbstani In tinea auf dtn fuel «antat * dta injector · aufattckbartn zuaat * - container is provided, and dtfl 1 «area dt» Anettses as Zuiatfbthfilttr tint torch tin Ttrtehltbbtrtt Rohntöek In eintr DurohlaSiagt öfftnbart sealing ftrgtathta let that dat Ttr * schiebbarβ Rohretack In tints sit dts Antat * Ytrblndbartn Vtrbverbindaatuek is stored, and that ftratr did tob dtr sealing facing away from the sliding pipe piece as sealing Edition of Spritzansate is geatalttt. Sin d-type two-chamber injector represents a piston assembly with an additional container attached, the stability of the active ingredients being activated with additional substances In the internal chambers through perfect sealing of the injector against the additional container under sterile Conditions reached vlrd it is only necessary to hold the ingredient to move the connecting piece in the direction of the injector, the open seal being opened bsv · a luaätslichta The sealing element is either removed or severed. The contents of the additional container then enter the Svrltsanaat sealingly surrounding, slide-in ear piece and is tob there absorbed into the injector · After this has been done, the filter with connection and sliding drill bit can be removed from the injection nozzle of the injector. Sit in the mixture formed by the injector is ready for use.

In a EveckmäSigen training the connecting piece can be designed so that the additional containers with injectors Ttrachit-

109843/0521

ÄAD ORiGfNAL

Because of its size more combined, without the connection piece on the same side and daa Taraohiabbara Kohrstück are also changed mUasan * On this weiaa an arhablioha becomes Simplification achieved before assembly.

In a further embodiment is the invention may also gvack * • ftBig aaittt tHe daa Connector "it Ainar threaded on dan Ansäte · β Zusatsbehältere ά aufaohraubbar, and that custody as a seal ia region of this threaded a · behind" aohnittanan inner edge the connector ain sealing element is located, wherein aina central recess daa connecting piece is designed as a guide dta Terschiebbaren Rohratüoks.

Ba can be famer τοrteillich that the connector on the (uta injector facing oeite an outer fora des Yer push bar en liohrattioka adjusted neckline on waist, in dia the sliding earpiece when preparing the Injector enters in such a way that oils prevent the possible displacement of the earpiece relative to the container and connector bagranit · This makes it particularly easy to handle · A correspondingly designed annular counter bearing aa in » i> nd of the Kohratüoka on the jector side enables a completion The injectors are made during manufacture by pressing the injector tapes into the sliding earpiece without causing any Bohratück i »connecting piece varachoben«

possibly with high demands on the Abeol pouring Yoriusehende Diohtuagsele «ent can after the abiusohlieflenden Suaataaiem in different ^ aiaa either as a removable cap,

as a perforable partition or as a seal swlsonsu dta connection piece and dta Ttrschiebbaren Bohrttttek be trained. In some cases, the existing seal is sufficient the connecting piece and the soles of the Bthrstflok, whose passage openings trtt to dta Vtrtohobenn dta ttrtohitbbartn Pipe section in dlt usage position old dta Inataraua dta Additional container * kosannliitrtn · Here, if necessary, sur Increase the sealing to be interchangeable so that the door can be centralized Ausnehaung dta connector tint Diohtaag gtgtaübtr dta Ytrtohitbbarta piece of pipe arranged let · Ditse seal can Partially designed as a tin alt dta connecting piece, one-story fiingbulst be formed

Bti tintr recommendable execution fona is the sliding one Bobrstüek to dta τοπ injector completed and turned away bath an stintr face ait tinta fiingansats τerathen, with behind dta bottom part transverse sitr longitudinal axis dlt DurohlsAaasnthaungen for the contents of the supplement "container" are approved.

In tintr further sweckaäßigen version is dtr Zweikaeeer-in i tktor, beets starting from injector Terschlebbarea Kohrstück, Vtrbindungsstück and Zusatsbehälter, ready-old gtbraaohsfertige Kinheit aontiert. SIt Sinielteile dtt Zwtikaaatr-Injectors are advised old innststofforate parts, for example as Syritsgadteile, manufactured

Dtr ZusatibehUttr contains either tlnta gaaagand grtUta I * ftraua odtr ist dnroh material «ad Waadstftrkt Ttrforatar, at IaI tiat adjustment ta Volaataiadtraagtn aöglieh 1st «

Ia dtr Ztitamtaf let tia AasfUhraagabtitBlal dta (lagansttjaitt dtr Xrfindung toheaatisoh dargttttllti ta stigaat

- 7-., 109843/0521

Figure 1 shows a Zwelkaaaer injector according to the invention, assembled ready for use.

FIG. 2 shows a section of the two-caaer injector, with the connector sue Gebrauohsfertlgaachen has been moved,

Figure 3 shows a section corresponding to Figure 2 according to dera Pulling up the contents of the «Susati container with functionala injector

In Figures 1 to 3, a two-caaer injector is shown, which one formed in the fora of a plunger injection syringe Has injector 1, to the via a in a connector 2 displaceable drill bit 3 an additional container 4 is connected in a housing 5 of the injector 1 is in A displaceable piston 6 is mounted in a known manner. On the housing 5 there is a fuel seed 7 which merges into a conical outlet 8. On Spritsansate 7, that's dea Injector 1 applied end of the sliding bobbin 3 attached In the sliding pipe section 3 are transverse to the longitudinal axis Durchlaßausnehaungen 9 provided «The dea additional container The front end of the displaceable earpiece 3 has a bottom part 10 and a ring attachment 11, which is attached to the inner part Surface of an undercut inner edge 12 of the Connector 2 overlying cap-like sealing elements 13 is present. If necessary, the sealing between the displaceable tire piece 3 and the connecting piece 2 can be improved by means of an annular seal.

109843/0521

DIM · can locate it at a recess in the connection 2 tin-piece forged annular bead tnt be formed. As a result, despite ε production-related fluctuations in size, dee Diameter of the recess 17 and the Rohretück 3 a safe Sealing achieved

The connecting piece 2 has a screw sleeve 14 and is old the internal thread of which can be screwed onto a correspondingly adapted threaded part of an attachment 15 of the additional container 4. The connector 2 shows a partially conical recess 17, which is deepened by longitudinal ribs 16, which is adapted to the outer contour of the end part of the sliding earpiece 3 Pipe section 3 also has an annular counter bearing 18 and is in a central recess 19 of the connector 2 slidably mounted

In injector 1 there is a first chamber I ₉ while a second Cairo II is formed by the inner space of the additional container 4. Corresponding components of the drug to be used as a mixture can be accommodated in both channels.

The two-chamber injector is mounted in the position shown in Figure 1 Location and · delivered to Ready to Make the injector is the connecting piece 2 "it de" screwed Zusatebehälter 4 to move so against the Spritsansats 7 of the injector 1 that the injector-indtell of the sliding tube section 3 rests in the recess 16 of the connecting piece · The end of the sliding tube 3 on the side of the additional container 4 moves into the inner space

1 09843 / ΠΒ2 1

fiAD ORiGINAL

of the additional container “rs 4” and the. ”and part 11 lifts the cap-like sealing element 13, which falls into the interior of the additional container 4. In addition, the passage recess a 9 are free from their sealing contact on the inner circumference of the central recess 17 of the connecting piece 2 and now communicate with the interior of the additional container 4. This process is explained in FIG so that the liquid contents of the additive container 4 are drawn out of chamber II · (the distribution of dry substance and liquid can also be reversed if necessary ») it mixes with the contents of chamber I» so that the ready-to-use drug is now available. Then the additional container 4 with the connecting piece 2 and the sliding nozzle 3 can be removed, and the injector is ready for use (Figure 3).

Hit the features of the invention according to yourself a ready to use Manufacture a removable two-chamber injector, which is preferred in veterinary medicine «but can also be used for special applications in human medicine. The conical outlet of the Injector can also be advantageous to attach the known Hypodermic needles be designed.

Because of the low production costs, such two-chamber » Injector · »also outside the medical field for such · Usable for purposes of application in which «in · mixture before use au · two separately tu stored · «substances must be produced« For example, a similar injector can be used as a cream

109843/0521

ORIGINAL

Make a syringe, with a freeze-dried » Storable starting product and in which Kasaer Π contains an amount of liquid required for dissolution.

• 11 -

109843/0521

«A ORiGfNAL

Claims (1)

Expectations U Areikaminer injector, especially for veterinary purposes, with an injector designed as a plunger syringe which receives a first iCamaer for a substance to be mixed, characterized in that ds3 a second Chamber to accommodate another Substana to be table in one on the Spritzansata (7) of the injector (1) attachable 2usat «container (4) is provided and dall in area of approach (15) εη additional filter one through a Slidable earpiece (3) reveal in a scroll leaf Sealing (9.17 »13) is provided because it is slidable »Ear piece (3) in a connecting piece that can be connected to the extension (15) (2) is supported, and that furthermore the linden of the sliding ear piece (3) facing away from the seal is designed as a sealing support aa jprit kit (7). 2m »orriclitunj still claim I, since ο uru ^r r e 1: β η η draws, d: i.» the /erbin<3un.iS3tück (2) with a screw thread (14) on the ^ nsat «(Γ>) <3 of the additional container (4) can be screwed, and Ua- * itself sls .bdicIituKuj; in the area of this screw sleeve on an "in-cut inner edge (1?) of the connecting piece (?) there is a r / icUtuugeelemtnt (13), with a central AusnehMut ^; (19) of the connecting piece (2) is designed as a guide for the displaceable.; Ear; icks (3). 1098U / 0521 3 · Device according to claim 2, characterized in that the connecting piece (2) on the side facing the injector (1) by means of a longitudinal rib (16) a partially conical recess (17) fitted to the outer fona of the displaceable drill hole (5) ) which the displaceable pipe section (3) enters when the injector (1) is ready for use in such a way that it limits the possible displacement of the pipe section (5) with respect to the additional container (4) and connecting piece (?). 4. Apparatus according to claim?, Characterized in that de8 des Pichtun ^ seleaent is designed in the form of a rm inner edge (12) sealingly abutting, detachable cap (13). Device according to claim 2, d ο characterized in that the displaceable tubular piece (3) is closed at the end facing away from the injector (1) and has a ring attachment (11) on its end face, with the bottom part (10) behind the bottom part (10) across the length IXirchlaßauenehiüungeti (9) are provided for the content of the additional containers (4). 6, apparatus according to claim 1, characterized in that ca; 3 & Sweiknnner he injector "it injector (1), sliding liohrstück (3), connecting piece (2) and Zusatzbehalter (4) as a ready-mounted unit 1st · 1098 ^ 3/0521 - ¹ ^ - ÄAD ORIGINAL 7. The device according to claim 1, characterized in that <: e k β η η -draws, daii in iitrtlch dtr central recess (19) of the connection piece (2) tint seal ßgtnübtr de · verehlebbartn uohrstück (3) is arranged. 8 »Device according to claim 7, characterized in that r θ k β η η draws, that the seal is a HingvuXst formed in one piece with the connecting piece (2). 9 · Device according to claim 1 or 6 »characterized in that g β identifies, that dtr injector (1), the displaceable Rohretiick (3), the connecting piece (2) and dtr / additional container <4) Synthetic material are tilted. 1098A3 / 0521 Blank page