DE1728885U - COLPOMICROSCOPE. - Google Patents
COLPOMICROSCOPE.Info
- Publication number
- DE1728885U DE1728885U DEV6221U DEV0006221U DE1728885U DE 1728885 U DE1728885 U DE 1728885U DE V6221 U DEV6221 U DE V6221U DE V0006221 U DEV0006221 U DE V0006221U DE 1728885 U DE1728885 U DE 1728885U
- Authority
- DE
- Germany
- Prior art keywords
- filter
- blue
- beam path
- colpomicroscope
- blocking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000005855 radiation Effects 0.000 claims description 6
- 230000005284 excitation Effects 0.000 claims description 5
- 230000000903 blocking effect Effects 0.000 claims description 3
- 244000052769 pathogen Species 0.000 claims 1
- 230000001717 pathogenic effect Effects 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000003855 cell nucleus Anatomy 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
Landscapes
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Microscoopes, Condenser (AREA)
Description
M 2O170.U3.5B M 2O170.U3.5B
VEB Carl Zeiss JENA Erfinders Drc Ludwig Otto, JenaVEB Carl Zeiss JENA inventor Dr c Ludwig Otto, Jena
KoIpomikroskopCollomicroscope
Der Gegenstand der Neuerung betrifft eiα Kolpomikroskop zur Beobachtung von Vorgänge* in Körperhöhlen lebender Organismen»The subject of the innovation concerns a colpomicroscope for observing processes * in body cavities living organisms »
Bei den bisher bekannten Kolposkopen erfolgt die Beobachtung eines Objektes mit dem sichtbaren von einer Lichtquelle erzeugten Licht, so daß damit nur die ab=· sterbenden oder bereits abgestorbenen Zellkerne der obersten verhornten Zellschicht sichtbar werdeae Weiter= hin sind auch Mikroskope für Intravital-Untersuchungea bekannt, die sich bei der Beobachtung ultravioletter oder blauer Strahlen bedienen und die es erforderlich machen, daß dem zu untersuchenden Körperteil fluoreszierende Stoffe einverleibt werden. Der Nachteil dieser Mikroskope besteht in der Anwendung des ultravioletten Lichtesj, welches bei längerer Einwirkung auf den lebenden Körper Schädigungen hervorruft. In the previously known colposcopes, an object is observed with the visible light generated by a light source, so that only the dying or already dead cell nuclei of the uppermost keratinized cell layer are visibleea e Furthermore, microscopes for intravital examinationsa are also known which use ultraviolet or blue rays for observation and which make it necessary that fluorescent substances are incorporated into the part of the body to be examined. The disadvantage of these microscopes is the use of ultraviolet light, which causes damage if the living body is exposed for a long period of time.
Gemäß der Neuerung werden diese Nachteile dadurch beseitigt^ daß im Beleuchtungsstrahlengang ein UV-Sperr= filter und vorzugsweise ein Blaufilter vorgesehen sind» so daß nur blaues Licht als Erregerstrahluag auf dasAccording to the innovation, these disadvantages are eliminated in that a UV barrier = in the illuminating beam path filter and preferably a blue filter are provided »so that only blue light as an exciter beam on the
G 2877G 2877
vorzugsweise fluoroehroinierte Objekt gelangt 12nd daß durch, ein im Beobaehtungsstrahlengang angeordnetes Interferenz« Spiegelfilter das Fluoreszejasslieht von der im Objekt reflektierten Erregerstrahlung getrennt wird* Da das In= t©r£@r®as=>Sp lege !filter noch Reste der Srregerstrahluag hindurchläßt, ist im Beöbaehtungsstrahlengang ein Sperr=· filter vorzusehen^preferably fluoro-hydrated object passes 12nd that through, an interference arranged in the observation beam path " Mirror filter the fluorescence differs from that in the object reflected excitation radiation is separated * Since the In = t © r £ @ r®as => Sp lege! filter still remains of the exciter jet passes through, there is a blocking in the observation beam path = filter to be provided ^
Eine beispielsweise Ausführung des Gegenstandes der Neuerung ist in d©r Zeichnung im Schema dargestellt«,An example implementation of the object the innovation is shown in the drawing in the scheme «,
In dem Strahlengang einer QueGksilberhöehstdruck= dampflampe 1 ist ©in W~Sperrfilt@r 2 angeordnet.In the beam path of a maximum mercury pressure = Steam lamp 1 is arranged in W ~ blocking filter @ r 2.
Hinter dieeem Filter befindet sish ©in Blattfilter 3 s w@lel3.es nur des. blauen Anteil des sishtbaren Farben= spektrims hindurchläßt. Dieses blaue Licht wird durch ©ia Iaterfereng°Spiöge!filter 4- als Erregerstrahluag auf ein fliioroehromiertes Objekt 5 abgelenkt» Das dort entstehende Fluoreszenzlicht gelangt zusammen mit einem Rest der reflektierten blauen Erregerstrahlung auf das erwähnte Interf®reaz=.Spiege!filter 4 9 welches die Strahlen d@s Fluore&zensliehtes ungehindert zum Okular 6 hindurtJhläßt uM den Rest der blauen Erregerstrahlen in den BeleuGhtungpstrahlengaag zurückwirft« Mit der Ziffer 7 iftt das beobachtende luge bezeichnet. Da das Interferenz= Sperrfilter 4 noch einen geringen Teil des Blaulichtes der Erregerstrahluag hindurchläßt s ist ssur Absorption dieser Strahlen ®ia orangefarbenes Okular=Sperrfilter 8 vorgesehen«Behind this filter is sish © in leaf filter 3 s w@lel3.es only lets through the blue part of the visible color spectrum. This blue light is deflected by © ia Iaterfereng ° Spiöge! 4- filter as Erregerstrahluag a fliioroehromiertes object 5 »The fluorescent light produced there comes together with a remainder of the reflected blue excitation radiation to the mentioned Interf®reaz = .Spiege! Filter 4 9 which the rays of the fluorine and zensliehtes pass unhindered to the eyepiece 6 so that the remainder of the blue excitation rays are reflected back in the illumination beam. The number 7 denotes the observing eye. Because the interference rejection filter = 4 for only a small portion of blue light can pass the Erregerstrahluag s is ssur absorption of this radiation ®ia orange eyepiece = cut filter 8 is provided "
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEV6221U DE1728885U (en) | 1956-03-13 | 1956-03-13 | COLPOMICROSCOPE. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEV6221U DE1728885U (en) | 1956-03-13 | 1956-03-13 | COLPOMICROSCOPE. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE1728885U true DE1728885U (en) | 1956-08-30 |
Family
ID=32694121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEV6221U Expired DE1728885U (en) | 1956-03-13 | 1956-03-13 | COLPOMICROSCOPE. |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE1728885U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1254289B (en) * | 1962-01-26 | 1967-11-16 | Dr Mohamed Sherif Abdel Hadi | Device for microscopic examination of body cavities |
| DE1262502B (en) * | 1965-07-06 | 1968-03-07 | Wolf Gmbh Richard | Endoscope with color filter in the illumination beam path |
-
1956
- 1956-03-13 DE DEV6221U patent/DE1728885U/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1254289B (en) * | 1962-01-26 | 1967-11-16 | Dr Mohamed Sherif Abdel Hadi | Device for microscopic examination of body cavities |
| DE1262502B (en) * | 1965-07-06 | 1968-03-07 | Wolf Gmbh Richard | Endoscope with color filter in the illumination beam path |
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| Lines | Fraunhofer Lines |