DE10390696T5 - Adhesive sheet for promoting blood circulation using pyrolignin fluid and methods of making the same - Google Patents

Abstract

A method for producing an adhesive sheet for promoting blood circulation, the method comprising the following steps:
performing a fractional distillation of pyrolignin liquid twice for two to six months using a vessel whose ratio of width to height is between 1: 3 and 1: 8;
Adding 20-30% by volume of an activated carbon with a diameter of 0.5-2.0 cm to the fractionated pyrolignin liquid, and stirring the mixture for adsorption refining;
Mixing 10-20% by weight starch and 20-30% by weight crystalline cellulose with 60-70% by weight of the pyrolignin liquid, and drying the mixture with a hot wind at a temperature of 40-50 ° C;
Mix 10-25% by weight of the pyrolignin liquid with 70-85.5% by weight starch, 0.5-1% by weight okapi, 0.5-1% by weight Kalopanacis cortex, 0.5-1% by weight centipede powder, 0.5-1% by weight aloe. Essence, 0.5-1 percent by weight chito oligosaccharide, 0.5-1 percent by weight Poria cocos, 0.5-1 percent by weight Agaricus pieade, 0.5-1 percent by weight seaweed powder and 0.5-1 percent by weight green tea powder, stirring the mixture Days at a ...

Description

technical area

The present invention relates on an adhesive sheet to convey of the bloodstream using wood acidic liquid or pyrolignin liquid, and a method of manufacturing the same. In particular relates The present invention relates to an adhesive sheet that is ceramic-treated surface has on the pyrolignin liquid is applied sealed, the pyrolignin liquid has gone through a number of procedures, starting with a three-step one Refining and processing, followed by a mixing process with effective components, a maturation process, a drying process and a mixing process, again with the effective components, at a predetermined ratio.

State of the art

Pyrolignin liquid is an acidic liquid with a pH of 3, which is generated when wood decomposes thermally becomes. Technically speaking, pyrolignin liquid is made by liquefying steam, the one out of a process Carbonization or charring of wood is obtained. Out for this reason, pyrolignin liquid enriched with effective components that are present in the wood and comes across different Industrial areas of keen interest.

In particular, pyrolignin liquid very popular as a healing additive in medical fields. One should however, be very careful with the pyrolignin liquid along with others Medication because it contains many harmful substances to Example tar, methanol or cresol. Before the pyrolignin liquid in a human body is applied, any harmful or poisonous substance through a high grade refining process same be removed.

Many are aware that the pyrolignin liquid is very effective in quickly subcutaneously harmful substances eliminate after it has been applied to the skin, and the further promote the metabolism, which can quickly heal a skin injury. To the pyrolignin liquid Apply to an epidermis using an adhesive sheet to be able you should get the pyrolignin liquid however, freeze to a certain extent. For example is disclosed in Japanese Patent Publication No. 1999-377391 a technique for processing pyrolignin liquid into fine powder, by the pyrolignin liquid with crystalline cellulose, starch and PCS is mixed and dried by mixing the mixture at 50 ° C is disclosed. Another Japanese patent application No. 99-207184 and filed utility model and device application No. 99-5455 an adhesive sheet to convey of the bloodstream, in which a mixture of dry pyrolignin fluid and strength and Spray adsorbing effective components applied to the plate becomes.

The above technologies have been proven however, proved insufficient to completely remove many harmful ones Substances contained in raw pyrolignin liquid, and the activation of the effective components and their hypodermic absorption remained questionable as a simple mixing process of the effective ones Components could not guarantee such effects.

epiphany the invention

Thus, there is an object of the present Invention therein, an adhesive sheet for promoting blood circulation under Use of pyrolignin liquid and to provide a method of making the same.

To solve the above call, created a method for producing an adhesive sheet, wherein one side of a ceramic treatment for the purpose of applying a Mixture of pyrolignin liquid, which are free of harmful substances is, with other effective components, namely Elvan, Agaricus pieade and subjected to dry centipedes to promote blood circulation and hypodermic absorption, the Mixture has undergone a ripening process, followed by a drying process using a fluid bed dryer, to maximize activation of the effective components and mix a very small amount of effective components evenly. Finally the surface of the Adhesive sheet on which the pyrolignin liquid with a much stronger effect applied to the bloodstream, attached to the skin.

Best mode to perform the invention

The following is a preferred one embodiment of the present invention.

First, here is a method for producing an adhesive sheet using pyrolignin liquid, which has the following steps:
a first step of collecting steam resulting from carbonization (or burning) of wood material, naturally cooling the steam to get pyrolignin liquid therefrom, and leaving the pyrolignin liquid in a vessel for a predetermined period of time until the liquid settles in has three layers separated;
a second step of extracting the middle layer from this three-layer pyrolignin liquid and repeating a distillation gangs on the middle layer until the middle layer is sufficiently cleaned;
a third step of mixing the purified pyrolignin liquid with activated carbon to stir, and removing any harmful substances by an adsorption process;
a fourth step of heating the purified pyrolignin liquid by the activated carbon at a low temperature to remove harmful substances from the pyrolignin liquid by a fractional distillation method, and reheating the pyrolignin liquid at a high temperature to remove remaining harmful substances by the fractionated process Distillation;
a fifth step of mixing the pyrolytic liquid, which is free of harmful substances, with okapi, kalopanacis cortex, centipede powder and vegetable powder, stirring the mixture at a low speed and allowing it to mature for five to ten days;
a sixth step of adding starch and crystalline cellulose to the ripened pyrolignin liquid and drying at a predetermined temperature to produce pyrolignin powder;
a seventh step of performing spray drying or vacuum freezing on the pyrolignin powder;
an eighth step of mixing 20-60 of the pyrolignin powder with 40-80 of a mixture liquid containing starch, elvan powder and vegetable powder, stirring the mixture and performing a fluid bed drying operation on the mixture at low temperature; and
a ninth step of sealing the final pyrolignin mixture made so far in an SMMS adhesive sheet, one side of the sheet being subjected to a ceramic surface treatment to be in contact with the skin, and the other side being coated with a film.

What an apparatus for fractional Distillation in the first step concerns the ratio of Width to length of the still between 1: 3 and 1: 8. If the ratio is below 1: 3, it becomes very difficult to get the pyrolignin liquid to get because of the contact area the middle layer compared to the total volume of the pyrolignin liquid is relatively large. If the ratio however over 1: 8, the still is too large to use, though he might be able the liquid to separate much better. The separation or distillation preferably takes two up to six months.

If the separation is within two months, you can not adequately purified pyrolignin liquid receive. On the other hand, the separation period cannot exceed six Last for months because there is nothing more to separate.

This is particularly useful in the third step activated carbon adsorption process used to remove harmful Substances with a high boiling point, for example benzopyrene, phenol and cresol. Activated carbon preferably used has a diameter from 0.5 cm-2.0 cm, and the volume of activated carbon to be used is 20-30 des Total volume of the pyrolignin liquid. If the activated carbon is shorter than 0.5 cm, the adsorbability is not very good, and if the activated carbon longer than 2.0 cm, it is easily broken during the stirring step, causing activated carbon suspended matter arise. If the total volume of activated carbon is below 20% of the Total volume, including the pyrolignin liquid, the adsorption capacity is also very low. If the volume However, if the activated carbon exceeds 30% of the total volume, the adsorption capacity becomes so excessive that some effective components could be adsorbed. A desirable one stirring frequency is 20-60 times per minute since the adsorption efficiency becomes poor if it is below 20 and since the activated carbon could break if it is over 60.

The fourth step is the pyroligneous refined first at a low temperature of 60-70 ° C and then at a high temperature of 100-110 ° C refined. The refining process taking place at the low temperature serves harmful Substances with a low boiling point, e.g. methanol (boiling point: 64.1 ° C) to remove, and the refining process taking place at high temperatures serves harmful Substances with a boiling point of around 100 ° C, which is also the boiling point of Water is to be removed. In particular, 100 ° C are chosen to a major component of the pyrolignin liquid, i.e. Acetic acid, the Boiling point 117.8 ° C is, to protect.

In the sixth step, the composition ratio is Mixture (strength: crystalline cellulose) for 60-70 % By weight of the pyrolignin liquid 10-20 : 20-30%. The mixture is then based on a hot wind drying process dried, in which a dry air flow of 40-50 ° C from both Directions past the mixture.

In the fifth step, this continues Plant powder from aloe essence, chito-oligosaccharide, poria cocos, Agaricus pieade, seaweed powder and green tea powder together. More accurate said 10-25% by weight the pyrolignin liquid, 70 to 85.5 % By weight starch, 0.5-1 Wt% okapi, 0.5-1 Wt% Kalopanacis cortex, 0.5-1 % By weight centipede powder, 0.5-1% by weight Aloe essence, 0.5-1 % By weight chito oligosaccharide, 0.5-1 % By weight Poria cocos, 0.5-1% by weight Agaricus pieade, 0.5-1 % By weight of seaweed powder and 0.5-1 % By weight of green tea powder. A suitable speed of rotation of an agitator is between 30 and 80 times a minute, and the stirring and ripening continue until the final viscosity of the mixture 0.2-0.3 Pa • s reached.

The seventh step is matured viscous pyrolignin mixture is sprayed through a nozzle and is dried to particles of size less than 0.5 mm. After that, the particles are subjected to a rotary drying process subjected in a turning wind. Furthermore, the dry mixture becomes one Freeze-drying process at a temperature between 20 ° C and -40 ° C under reduced pressure from about 0.02-0.14 psi subjected to sublimate moisture therein.

The eighth step will be too the pyrolignin mixture for drying starch, elvan powder and vegetable powder added. This mixture is placed in a vessel, the lower section of which a perforated plate is placed in a special way. Hot wind flows into the perforated plate for an extremely strong fluidization movement in the vessel to effect, whereby the mixture is dried. The dry mixture will then by a blower released, and its particle size becomes even. The Plant powder includes Aloe Essence, Chito Oligosaccharide, Poria cocos, Agaricus pieade, Kelp powder, propolis, red ginseng and green tea powder. As for the Elvan powder As concerns, an Elvan is pulverized to a grain size of 60-300 mesh. If the Elvan particles are smaller than 60 mesh, they are so tiny that she through a hole (or an opening) of the adhesive sheet surface member can get whereas when larger than 300 mesh, the Elvan particles are so large that they do so to lead can, that itself a patient who applies the adhesive sheet to his skin feels uncomfortable. Preferably comprises the mixture 15-25% by weight pyroligneous, 60-76 % By weight starch, 6-7% by weight Elvan powder, 0.5-1.0 Wt% aloe essence, 0.5-1.0 % By weight chito oligosaccharide, 0.5-1.0% by weight poria cocos, 0.5-1.0% by weight Agaricus pieade, 0.5-1.0 % By weight seaweed powder and 0.5-1.0% by weight Green tea powder.

The ninth step is usually a Nonwoven fabric of the SMMS type for used the adhesive sheet. In particular, the nonwoven is a four-layer, that of a spunbonded fabric, a meltblown fabric, a meltblown fabric and a spunbonded web. In this way, the pyrolignin liquid particles penetrate not easy on the outside. Further becomes a side of the adhesive sheet that comes into contact with the skin with a liquid adhesive, namely Pine resin, a powdered ceramic substance with a size of 150-300 mesh as well as the pyrolignin mixture solution sprayed. The other side of the adhesive sheet is covered with an (aluminum) film, creating effective components in the pyrolignin liquid mixture outward completely protected can be.

Embodiment 1 - Refining of pyrolignin liquid

An oak was made in an industrial oven at 1300 ° C carbonized, and a manifold installed over the industrial furnace is, collected steam generated by the carbonization. Later the collected steam filled in a separate container, and one installed in the container Cooling tube liquefies the Steam all the time. Pyrolignin liquid thus obtained was placed in a glass bottle sealed with a diameter of 20 cm and a height of 130 cm and stored for three months. After a while, the middle class was separated collected, and after two months it was returned to the previous one used glass bottle of the same size to fill the middle class distill. In particular, the vessel for collecting the pyrolignin liquid made of resin to prevent the vessel from being exposed to the acidic pyrolytic liquid (pH ≈ 3) is eroded.

There were 20 kg of the distilled Layer of the pyrolignin liquid into an agitator placed, and 25 vol .-% activated carbon with a diameter of 1 cm were added. The mixture was then run at a rate of 40 times each Minute stirred. After the pyrolignin liquid refined, it was passed through a non-woven fabric, to remove the activated carbon.

After the pyrolignin liquid had been refined by adsorption of the activated carbon them at 60 ° C for 30 minutes heated to harmful Remove substances with a low boiling point. The pyrolignin was heated again at 100 ° C for 15 minutes to remove harmful substances with a medium boiling point.

Embodiment 2 - manufacture of pyrolytic liquid powder

20 kg of the embodiment 1 refined pyrolignin liquid obtained was 3 kg starch and 7 kg of crystalline cellulose mixed. To stir the mixture happened a hot one Wind at a temperature of 45 ° C from both directions through the mixture.

20 kg of the resulting pyrolignin liquid were again with 8 kg strength, 80 g okapi, 70 g kalopanacis cortex, 80 g centipede powder and 80 g green tea powder mixed and in a stirrer stirred at a speed of 60 times per minute and subsequently matured for seven days. The ripening temperature was kept at 30 ° C.

Later 20 kg of the ripened pyrolignin mixture was placed in a cooling container at 35 degrees below zero and freeze-dried under reduced pressure. 20 kg of processed pyrolignin liquid thus obtained was injected into a fluidized bed dryer and a hot wind was blown at 40 ° C therein. To the dry pyrolignin liquid was added 50 g propolis, 80 g red ginseng and 80 g chito oligosaccharide while the pyrolignin liquid was coated and dried. Furthermore, 1 kg of the tro mixed fluidized bed powder and 1 kg of the freeze-dried powder.

Finally 2 kg of dry Pyroligneous powder mixed with other effective components, i.e. 7.2 kg starch, 600 g Elvan powder at 200 mesh, 40 g aloe essence, 80 g chito oligosaccharide, 85 g poria cocos, 95 g agaricus pieade, 90 g seaweed powder and 100 g green tea powder, to produce an end product.

Embodiment 3 - Manufacturing an adhesive sheet

Using a spunbond and a meltblown fabric with a width of 5 cm and a height of 10 cm, a four-layer non-woven fabric, that of a spunbond, a meltblown fabric, a meltblown fabric and a spunbond fabric was made. With two pieces of Fleece became a mixture of pine resin and ceramic at 250 mesh sprayed on one side of a fleece. This page becomes one Inside. In contrast, an adhesive was applied to the other three outsides of the two nonwovens applied, and these two nonwovens adhered together. Then 3.5 g of that produced in embodiment 2 were Mix added and the other side was attached to seal the mixture in the adhesive sheet and the outer surface of the The adhesive sheet was provided with foil.

While the invention with reference to certain preferred embodiments same has been shown and described, those skilled in the art will recognize that various changes in in terms of shape and details can be made without on the nature and scope of the invention brought about by the attached claims are defined to deviate.

industrial applicability

The adhesive sheet, the pyrolignin liquid according to the present Invention used is able to enhance the medical effects of the pyroligneous, this means improve blood circulation by removing harmful components that are in the pyrolignin liquid are included completely are removed, whereby a separate ripening process is carried out, to maximize the activation of effective components, with a Fluid bed drying process is carried out to remove component particles to make even adding many materials that are known to be the best Promote blood circulation, including Centipede or Okapi, and using a four-layer adhesive sheet, at one side is covered with foil and the other side, the in contact with the skin should come, is subjected to a ceramic treatment.

Summary

It is an adhesive sheet to promote the Blood circulation using pyrolignin fluid disclosed. In particular goes through the pyrolignin liquid a three-stage refining and processing and is made with okapi, Houttuynia cordata, Kalopanax pictus (i.e. thorny tree) and dry Centipede mixed. Subsequently the mixture is over matured for a predetermined period of time and in the adhesive sheet, which has a surface treated with ceramic, sealed. For this purpose, the pyrolignin liquid is predominantly derived from the Carbonization of a wood material collected. Later the liquid by an activated carbon adsorption process and a process of a fractional Distillation cleaned and mixed with effective components. The mixture is then subjected to a number of processes, including stirring, ripening, Fluid bed drying, spray drying and freeze drying processes. The Pyrolignin liquid mixture dried in this way is in turn with strength, Elvan and effective components mixed and in the adhesive sheet with a ceramic-treated surface sealed. The adhesive sheet of the invention can advantageously to remove any harmful Components contained in raw pyrolignin liquid are used become. Furthermore, the adhesive sheet maximizes an activity of effective ones Components by adding materials that are good for the bloodstream are and easily penetrate subcutaneous tissue, and further maximized a maturation process of the Mixture. Furthermore, the ceramic surface treatment of the adhesive sheet improves a medical effect regarding of the bloodstream.

Claims (2)

A method of making an adhesive sheet for promoting blood circulation, the method comprising the steps of: twice performing a fractional distillation of pyrolignin liquid for two to six months using a vessel whose ratio of width to height is between 1: 3 and 1: 8 ; Adding 20-30% by volume of an activated carbon with a diameter of 0.5-2.0 cm to the fractionated pyrolignin liquid, and stirring the mixture for adsorption refining; Mixing 10-20% by weight starch and 20-30% by weight crystalline cellulose with 60-70% by weight of the pyrolignin liquid, and drying the mixture with a hot wind at a temperature of 40-50 ° C; Mix 10-25% by weight of the pyrolignin liquid with 70-85.5% by weight starch, 0.5-1% by weight okapi, 0.5-1% by weight Kalopanacis cortex, 0.5-1% by weight Centipede powder, 0.5-1 weight percent aloe essence, 0.5-1 weight percent chito oligosaccharide, 0.5-1 weight percent Poria cocos, 0.5-1 weight percent Agaricus pieade, 0.5-1 weight percent seaweed powder and 0. 5-1 weight percent green tea powder, stirring the mixture for seven days at a stirring speed of 30-80 times / minute and ripening the mixture; Performing a spray drying on the ripened pyrolignin liquid mixture or performing a freeze drying on the ripened pyrolignin liquid mixture at 20 ° C below zero to 40 ° C below zero at a reduced pressure in the range of 0.02-0.14 psi; Mix 20-60% of the pyrolignin liquid mixture with 40-80% of a mixture consisting of 15-25 weight percent pyrolignin liquid, 60-76 weight percent starch, 6-7 weight percent Elvan powder at 60-300 mesh, 0.5-1.0 weight percent aloe -Essence, 0.5-1.0 weight percent chito oligosaccharide, 0.5-1.0 weight percent poria cocos, 0.5-1.0 weight percent agaricus pieade, 0.5-1.0 weight percent seaweed powder and 0.5 -1.0% by weight of green tea powder, stirring a resulting mixture and performing a fluidized bed drying operation to produce a mixed powder; and sealing the mixed powder produced in an adhesive sheet, the adhesive sheet being a four-layer nonwoven fabric consisting of a spunbonded fabric, a meltblown fabric, a meltblown fabric and a spunbonded fabric, one side of the plate having a mixture of ceramic at 150- 300 mesh is sprayed with pine resin and the other side of the plate is covered with foil. An adhesive sheet to promote blood circulation Use of the manufacturing method according to claim 1.