DE102018217130A1 - Sunscreen with a combination of waxes and cetyl palmitate - Google Patents
Sunscreen with a combination of waxes and cetyl palmitate Download PDFInfo
- Publication number
- DE102018217130A1 DE102018217130A1 DE102018217130.0A DE102018217130A DE102018217130A1 DE 102018217130 A1 DE102018217130 A1 DE 102018217130A1 DE 102018217130 A DE102018217130 A DE 102018217130A DE 102018217130 A1 DE102018217130 A1 DE 102018217130A1
- Authority
- DE
- Germany
- Prior art keywords
- inci
- preparation
- cetyl palmitate
- wax
- melting point
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- FLPJVCMIKUWSDR-UHFFFAOYSA-N 2-(4-formylphenoxy)acetamide Chemical compound NC(=O)COC1=CC=C(C=O)C=C1 FLPJVCMIKUWSDR-UHFFFAOYSA-N 0.000 title claims abstract description 56
- 229940074979 cetyl palmitate Drugs 0.000 title claims abstract description 56
- PXDJXZJSCPSGGI-UHFFFAOYSA-N hexadecanoic acid hexadecyl ester Natural products CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC PXDJXZJSCPSGGI-UHFFFAOYSA-N 0.000 title claims abstract description 56
- 239000001993 wax Substances 0.000 title claims abstract description 38
- 230000000475 sunscreen effect Effects 0.000 title claims abstract description 20
- 239000000516 sunscreening agent Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 claims abstract description 79
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 claims abstract description 64
- 239000002537 cosmetic Substances 0.000 claims abstract description 35
- 238000002844 melting Methods 0.000 claims abstract description 32
- 230000008018 melting Effects 0.000 claims abstract description 32
- 238000000034 method Methods 0.000 claims abstract description 21
- 239000004904 UV filter Substances 0.000 claims abstract description 18
- -1 Glycol Ester Chemical class 0.000 claims description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 11
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 8
- 239000000839 emulsion Substances 0.000 claims description 8
- 235000003222 Helianthus annuus Nutrition 0.000 claims description 7
- 239000002253 acid Substances 0.000 claims description 7
- 229960005193 avobenzone Drugs 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 150000003839 salts Chemical class 0.000 claims description 7
- TYYHDKOVFSVWON-UHFFFAOYSA-N 2-butyl-2-methoxy-1,3-diphenylpropane-1,3-dione Chemical compound C=1C=CC=CC=1C(=O)C(OC)(CCCC)C(=O)C1=CC=CC=C1 TYYHDKOVFSVWON-UHFFFAOYSA-N 0.000 claims description 6
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 6
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical compound C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims description 6
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 claims description 5
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 5
- 239000007983 Tris buffer Substances 0.000 claims description 5
- 230000001476 alcoholic effect Effects 0.000 claims description 5
- 238000003287 bathing Methods 0.000 claims description 5
- 239000004204 candelilla wax Substances 0.000 claims description 5
- 229940073532 candelilla wax Drugs 0.000 claims description 5
- 235000013868 candelilla wax Nutrition 0.000 claims description 5
- FDATWRLUYRHCJE-UHFFFAOYSA-N diethylamino hydroxybenzoyl hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1C(=O)C1=CC=C(N(CC)CC)C=C1O FDATWRLUYRHCJE-UHFFFAOYSA-N 0.000 claims description 5
- 238000009472 formulation Methods 0.000 claims description 5
- IUJAMGNYPWYUPM-UHFFFAOYSA-N hentriacontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC IUJAMGNYPWYUPM-UHFFFAOYSA-N 0.000 claims description 5
- 229960005323 phenoxyethanol Drugs 0.000 claims description 5
- NPSJHQMIVNJLNN-UHFFFAOYSA-N 2-ethylhexyl 4-nitrobenzoate Chemical compound CCCCC(CC)COC(=O)C1=CC=C([N+]([O-])=O)C=C1 NPSJHQMIVNJLNN-UHFFFAOYSA-N 0.000 claims description 4
- 239000004808 2-ethylhexylester Substances 0.000 claims description 4
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 claims description 4
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 4
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims description 4
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 4
- 229960004881 homosalate Drugs 0.000 claims description 4
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 4
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 4
- ANZUDYZHSVGBRF-UHFFFAOYSA-N 3-ethylnonane-1,2,3-triol Chemical compound CCCCCCC(O)(CC)C(O)CO ANZUDYZHSVGBRF-UHFFFAOYSA-N 0.000 claims description 3
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- XVAMCHGMPYWHNL-UHFFFAOYSA-N bemotrizinol Chemical compound OC1=CC(OCC(CC)CCCC)=CC=C1C1=NC(C=2C=CC(OC)=CC=2)=NC(C=2C(=CC(OCC(CC)CCCC)=CC=2)O)=N1 XVAMCHGMPYWHNL-UHFFFAOYSA-N 0.000 claims description 3
- 229960001630 diethylamino hydroxybenzoyl hexyl benzoate Drugs 0.000 claims description 3
- 150000002170 ethers Chemical class 0.000 claims description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 3
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 3
- 239000004408 titanium dioxide Substances 0.000 claims description 3
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical compound C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 claims description 2
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 2
- 229940031723 1,2-octanediol Drugs 0.000 claims description 2
- MEZZCSHVIGVWFI-UHFFFAOYSA-N 2,2'-Dihydroxy-4-methoxybenzophenone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1O MEZZCSHVIGVWFI-UHFFFAOYSA-N 0.000 claims description 2
- CENPSTJGQOQKKW-UHFFFAOYSA-N 2,4,6-tris(4-phenylphenyl)-1,3,5-triazine Chemical compound C1=CC=CC=C1C1=CC=C(C=2N=C(N=C(N=2)C=2C=CC(=CC=2)C=2C=CC=CC=2)C=2C=CC(=CC=2)C=2C=CC=CC=2)C=C1 CENPSTJGQOQKKW-UHFFFAOYSA-N 0.000 claims description 2
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- QWGRWMMWNDWRQN-UHFFFAOYSA-N 2-methylpropane-1,3-diol Chemical compound OCC(C)CO QWGRWMMWNDWRQN-UHFFFAOYSA-N 0.000 claims description 2
- NGJJZCPADSICRI-UHFFFAOYSA-N 4-[[4,6-bis(4-carboxyanilino)-1,3,5-triazin-2-yl]amino]benzoic acid Chemical compound C1=CC(C(=O)O)=CC=C1N=C(NC(=NC=1C=CC(=CC=1)C(O)=O)N1)NC1=NC1=CC=C(C(O)=O)C=C1 NGJJZCPADSICRI-UHFFFAOYSA-N 0.000 claims description 2
- 229940073735 4-hydroxy acetophenone Drugs 0.000 claims description 2
- 235000004443 Ricinus communis Nutrition 0.000 claims description 2
- UBNYRXMKIIGMKK-RMKNXTFCSA-N amiloxate Chemical compound COC1=CC=C(\C=C\C(=O)OCCC(C)C)C=C1 UBNYRXMKIIGMKK-RMKNXTFCSA-N 0.000 claims description 2
- DTVQVQGCVNNOSX-UHFFFAOYSA-N bis(2-ethylhexyl) 2-[(4-methoxyphenyl)methylidene]propanedioate Chemical compound CCCCC(CC)COC(=O)C(C(=O)OCC(CC)CCCC)=CC1=CC=C(OC)C=C1 DTVQVQGCVNNOSX-UHFFFAOYSA-N 0.000 claims description 2
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 claims description 2
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- YSRSBDQINUMTIF-UHFFFAOYSA-N decane-1,2-diol Chemical compound CCCCCCCCC(O)CO YSRSBDQINUMTIF-UHFFFAOYSA-N 0.000 claims description 2
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 2
- HUVYTMDMDZRHBN-UHFFFAOYSA-N drometrizole trisiloxane Chemical compound C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)CC(C)CC1=CC(C)=CC(N2N=C3C=CC=CC3=N2)=C1O HUVYTMDMDZRHBN-UHFFFAOYSA-N 0.000 claims description 2
- HEAHZSUCFKFERC-UHFFFAOYSA-N ecamsule Chemical compound CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2=CC(C=C1)=CC=C1C=C1C(=O)C2(CS(O)(=O)=O)CCC1C2(C)C HEAHZSUCFKFERC-UHFFFAOYSA-N 0.000 claims description 2
- 150000002334 glycols Chemical class 0.000 claims description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 2
- 239000008172 hydrogenated vegetable oil Substances 0.000 claims description 2
- 125000001841 imino group Chemical group [H]N=* 0.000 claims description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 2
- MJVGBKJNTFCUJM-UHFFFAOYSA-N mexenone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=C(C)C=C1 MJVGBKJNTFCUJM-UHFFFAOYSA-N 0.000 claims description 2
- 229960001679 octinoxate Drugs 0.000 claims description 2
- 229960001173 oxybenzone Drugs 0.000 claims description 2
- LXTZRIBXKVRLOA-UHFFFAOYSA-N padimate a Chemical compound CCCCCOC(=O)C1=CC=C(N(C)C)C=C1 LXTZRIBXKVRLOA-UHFFFAOYSA-N 0.000 claims description 2
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 2
- 150000004885 piperazines Chemical class 0.000 claims description 2
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 claims description 2
- 239000011787 zinc oxide Substances 0.000 claims description 2
- 241000208818 Helianthus Species 0.000 claims 2
- UUGLJVMIFJNVFH-UHFFFAOYSA-N Hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1 UUGLJVMIFJNVFH-UHFFFAOYSA-N 0.000 claims 2
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 150000008107 benzenesulfonic acids Chemical class 0.000 claims 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 13
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 235000011187 glycerol Nutrition 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 244000020551 Helianthus annuus Species 0.000 description 5
- 239000000539 dimer Substances 0.000 description 5
- 239000004909 Moisturizer Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical class N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 description 4
- 230000001333 moisturizer Effects 0.000 description 4
- 229940116351 sebacate Drugs 0.000 description 4
- CXMXRPHRNRROMY-UHFFFAOYSA-L sebacate(2-) Chemical compound [O-]C(=O)CCCCCCCCC([O-])=O CXMXRPHRNRROMY-UHFFFAOYSA-L 0.000 description 4
- 230000037072 sun protection Effects 0.000 description 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 3
- PBFGMXZRJIUGKU-UHFFFAOYSA-N 3-decanoyloxybutyl decanoate Chemical compound CCCCCCCCCC(=O)OCCC(C)OC(=O)CCCCCCCCC PBFGMXZRJIUGKU-UHFFFAOYSA-N 0.000 description 3
- XTJFFFGAUHQWII-UHFFFAOYSA-N Dibutyl adipate Chemical compound CCCCOC(=O)CCCCC(=O)OCCCC XTJFFFGAUHQWII-UHFFFAOYSA-N 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 229940114374 butylene glycol dicaprylate Drugs 0.000 description 3
- 229940100539 dibutyl adipate Drugs 0.000 description 3
- DLAHAXOYRFRPFQ-UHFFFAOYSA-N dodecyl benzoate Chemical compound CCCCCCCCCCCCOC(=O)C1=CC=CC=C1 DLAHAXOYRFRPFQ-UHFFFAOYSA-N 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 229920002674 hyaluronan Polymers 0.000 description 3
- 229960003160 hyaluronic acid Drugs 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 229940032147 starch Drugs 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- YVLPJIGOMTXXLP-UHFFFAOYSA-N 15-cis-phytoene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CC=CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C YVLPJIGOMTXXLP-UHFFFAOYSA-N 0.000 description 2
- LFESLSYSZQYEIZ-UHFFFAOYSA-N 3-octanoyloxybutyl octanoate Chemical compound CCCCCCCC(=O)OCCC(C)OC(=O)CCCCCCC LFESLSYSZQYEIZ-UHFFFAOYSA-N 0.000 description 2
- ZCTQGTTXIYCGGC-UHFFFAOYSA-N Benzyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OCC1=CC=CC=C1 ZCTQGTTXIYCGGC-UHFFFAOYSA-N 0.000 description 2
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 2
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- 240000008415 Lactuca sativa Species 0.000 description 2
- 240000003183 Manihot esculenta Species 0.000 description 2
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- ISAOCJYIOMOJEB-UHFFFAOYSA-N benzoin Chemical compound C=1C=CC=CC=1C(O)C(=O)C1=CC=CC=C1 ISAOCJYIOMOJEB-UHFFFAOYSA-N 0.000 description 2
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 description 2
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 2
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 description 2
- PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
- 239000001245 distarch phosphate Substances 0.000 description 2
- 235000013804 distarch phosphate Nutrition 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
- 229960000601 octocrylene Drugs 0.000 description 2
- 239000010502 orange oil Substances 0.000 description 2
- OSORMYZMWHVFOZ-UHFFFAOYSA-N phenethyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCCC1=CC=CC=C1 OSORMYZMWHVFOZ-UHFFFAOYSA-N 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- LKUNXBRZDFMZOK-UHFFFAOYSA-N rac-1-monodecanoylglycerol Chemical compound CCCCCCCCCC(=O)OCC(O)CO LKUNXBRZDFMZOK-UHFFFAOYSA-N 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 235000012045 salad Nutrition 0.000 description 2
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical class OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- 230000036572 transepidermal water loss Effects 0.000 description 2
- 239000000230 xanthan gum Substances 0.000 description 2
- 229920001285 xanthan gum Polymers 0.000 description 2
- 235000010493 xanthan gum Nutrition 0.000 description 2
- 229940082509 xanthan gum Drugs 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- CRDAMVZIKSXKFV-FBXUGWQNSA-N (2-cis,6-cis)-farnesol Chemical compound CC(C)=CCC\C(C)=C/CC\C(C)=C/CO CRDAMVZIKSXKFV-FBXUGWQNSA-N 0.000 description 1
- 239000000260 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol Substances 0.000 description 1
- BUHVIAUBTBOHAG-FOYDDCNASA-N (2r,3r,4s,5r)-2-[6-[[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Chemical compound COC1=CC(OC)=CC(C(CNC=2C=3N=CN(C=3N=CN=2)[C@H]2[C@@H]([C@H](O)[C@@H](CO)O2)O)C=2C(=CC=CC=2)C)=C1 BUHVIAUBTBOHAG-FOYDDCNASA-N 0.000 description 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- 239000001244 (E)-1-(2,6,6-trimethyl-1-cyclohex-2-enyl)pent-1-en-3-one Substances 0.000 description 1
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 description 1
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- VPKMGDRERYMTJX-XEHSLEBBSA-N (e)-1-[(1r)-2,6,6-trimethylcyclohex-2-en-1-yl]pent-1-en-3-one Chemical compound CCC(=O)\C=C\[C@H]1C(C)=CCCC1(C)C VPKMGDRERYMTJX-XEHSLEBBSA-N 0.000 description 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 1
- OLUJUQKZMDLFII-UHFFFAOYSA-N 1-phenyloct-1-en-3-ol Chemical compound CCCCCC(O)C=CC1=CC=CC=C1 OLUJUQKZMDLFII-UHFFFAOYSA-N 0.000 description 1
- YVLPJIGOMTXXLP-UUKUAVTLSA-N 15,15'-cis-Phytoene Natural products C(=C\C=C/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C)(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C YVLPJIGOMTXXLP-UUKUAVTLSA-N 0.000 description 1
- YVLPJIGOMTXXLP-BAHRDPFUSA-N 15Z-phytoene Natural products CC(=CCCC(=CCCC(=CCCC(=CC=C/C=C(C)/CCC=C(/C)CCC=C(/C)CCC=C(C)C)C)C)C)C YVLPJIGOMTXXLP-BAHRDPFUSA-N 0.000 description 1
- PPVDHXWQWABSBC-UHFFFAOYSA-N 2-(2,6-diethyl-4-hydroxy-3,5-dimethoxyphenyl)-2-hexyl-1,3-dioxane-4,6-dione Chemical compound CCC=1C(OC)=C(O)C(OC)=C(CC)C=1C1(CCCCCC)OC(=O)CC(=O)O1 PPVDHXWQWABSBC-UHFFFAOYSA-N 0.000 description 1
- PFPQMWRASYNLMZ-LGIMBNBCSA-N 2-(3,4-dihydroxyphenyl)-3-[(2s,3r,4r,5s,6r)-3,4-dihydroxy-5-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5,7-dihydroxychromen-4-one Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 PFPQMWRASYNLMZ-LGIMBNBCSA-N 0.000 description 1
- DNRJTBAOUJJKDY-UHFFFAOYSA-N 2-Acetyl-3,5,5,6,8,8-hexamethyl-5,6,7,8- tetrahydronaphthalene Chemical compound CC(=O)C1=C(C)C=C2C(C)(C)C(C)CC(C)(C)C2=C1 DNRJTBAOUJJKDY-UHFFFAOYSA-N 0.000 description 1
- HMKKIXGYKWDQSV-SDNWHVSQSA-N 2-Pentyl-3-phenyl-2-propenal Chemical compound CCCCC\C(C=O)=C/C1=CC=CC=C1 HMKKIXGYKWDQSV-SDNWHVSQSA-N 0.000 description 1
- CZVOIAOPRGNENY-UHFFFAOYSA-N 2-butyloctyl 2-hydroxybenzoate Chemical compound CCCCCCC(CCCC)COC(=O)C1=CC=CC=C1O CZVOIAOPRGNENY-UHFFFAOYSA-N 0.000 description 1
- CLAHOZSYMRNIPY-UHFFFAOYSA-N 2-hydroxyethylurea Chemical compound NC(=O)NCCO CLAHOZSYMRNIPY-UHFFFAOYSA-N 0.000 description 1
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 description 1
- JRJBVWJSTHECJK-PKNBQFBNSA-N 3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one Chemical compound CC(=O)C(\C)=C\C1C(C)=CCCC1(C)C JRJBVWJSTHECJK-PKNBQFBNSA-N 0.000 description 1
- FGGSPCRNKDZEKY-UHFFFAOYSA-N 3-hexoxypentane-1,2,3-triol Chemical compound CCCCCCOC(O)(CC)C(O)CO FGGSPCRNKDZEKY-UHFFFAOYSA-N 0.000 description 1
- LZRZEWYKODIIJU-UHFFFAOYSA-N 3-hexyl-2-(9-phenylnona-6,8-dienoxy)benzoic acid Chemical compound CCCCCCC1=C(C(=CC=C1)C(=O)O)OCCCCCC=CC=CC2=CC=CC=C2 LZRZEWYKODIIJU-UHFFFAOYSA-N 0.000 description 1
- OXYRENDGHPGWKV-UHFFFAOYSA-N 3-methyl-5-phenylpentan-1-ol Chemical compound OCCC(C)CCC1=CC=CC=C1 OXYRENDGHPGWKV-UHFFFAOYSA-N 0.000 description 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 description 1
- MSHFRERJPWKJFX-UHFFFAOYSA-N 4-Methoxybenzyl alcohol Chemical compound COC1=CC=C(CO)C=C1 MSHFRERJPWKJFX-UHFFFAOYSA-N 0.000 description 1
- KKJKXQYVUVWWJP-UHFFFAOYSA-N 4-[(4,7,7-trimethyl-3-oxo-2-bicyclo[2.2.1]heptanylidene)methyl]benzenesulfonic acid Chemical class CC1(C)C2CCC1(C)C(=O)C2=CC1=CC=C(S(O)(=O)=O)C=C1 KKJKXQYVUVWWJP-UHFFFAOYSA-N 0.000 description 1
- YVSNOTITPICPTB-UHFFFAOYSA-N 4-methyl-2-(2-methylpropyl)oxan-4-ol Chemical compound CC(C)CC1CC(C)(O)CCO1 YVSNOTITPICPTB-UHFFFAOYSA-N 0.000 description 1
- GUOCOOQWZHQBJI-UHFFFAOYSA-N 4-oct-7-enoxy-4-oxobutanoic acid Chemical compound OC(=O)CCC(=O)OCCCCCCC=C GUOCOOQWZHQBJI-UHFFFAOYSA-N 0.000 description 1
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 description 1
- 229910052582 BN Inorganic materials 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 1
- PZNSFCLAULLKQX-UHFFFAOYSA-N Boron nitride Chemical compound N#B PZNSFCLAULLKQX-UHFFFAOYSA-N 0.000 description 1
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 description 1
- 108010087806 Carnosine Proteins 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- OOCCDEMITAIZTP-QPJJXVBHSA-N Cinnamyl alcohol Natural products OC\C=C\C1=CC=CC=C1 OOCCDEMITAIZTP-QPJJXVBHSA-N 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- 244000183685 Citrus aurantium Species 0.000 description 1
- 235000007716 Citrus aurantium Nutrition 0.000 description 1
- 240000002319 Citrus sinensis Species 0.000 description 1
- 235000005976 Citrus sinensis Nutrition 0.000 description 1
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- YEVACTAGDANHRH-UHFFFAOYSA-N Coniferan Chemical compound CCC(C)(C)C1CCCCC1OC(C)=O YEVACTAGDANHRH-UHFFFAOYSA-N 0.000 description 1
- 244000180278 Copernicia prunifera Species 0.000 description 1
- 235000010919 Copernicia prunifera Nutrition 0.000 description 1
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
- 235000000638 D-biotin Nutrition 0.000 description 1
- 239000011665 D-biotin Substances 0.000 description 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 241000522215 Dipteryx odorata Species 0.000 description 1
- QZKRHPLGUJDVAR-UHFFFAOYSA-K EDTA trisodium salt Chemical compound [Na+].[Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O QZKRHPLGUJDVAR-UHFFFAOYSA-K 0.000 description 1
- PNNNRSAQSRJVSB-SLPGGIOYSA-N Fucose Natural products C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O PNNNRSAQSRJVSB-SLPGGIOYSA-N 0.000 description 1
- 239000005792 Geraniol Substances 0.000 description 1
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- BYTORXDZJWWIKR-UHFFFAOYSA-N Hinokiol Natural products CC(C)c1cc2CCC3C(C)(CO)C(O)CCC3(C)c2cc1O BYTORXDZJWWIKR-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- SHZGCJCMOBCMKK-DHVFOXMCSA-N L-fucopyranose Chemical compound C[C@@H]1OC(O)[C@@H](O)[C@H](O)[C@@H]1O SHZGCJCMOBCMKK-DHVFOXMCSA-N 0.000 description 1
- 235000019501 Lemon oil Nutrition 0.000 description 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 1
- 229920000426 Microplastic Polymers 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 206010033546 Pallor Diseases 0.000 description 1
- 235000016856 Palma redonda Nutrition 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 244000028419 Styrax benzoin Species 0.000 description 1
- 235000000126 Styrax benzoin Nutrition 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 235000008411 Sumatra benzointree Nutrition 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 230000037338 UVA radiation Effects 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- SLHPMAOXNSLXEH-ZGVCCVRISA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] 5-oxopyrrolidine-2-carboxylate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C1NC(=O)CC1 SLHPMAOXNSLXEH-ZGVCCVRISA-N 0.000 description 1
- 230000009692 acute damage Effects 0.000 description 1
- 239000001361 adipic acid Substances 0.000 description 1
- 235000011037 adipic acid Nutrition 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- OOCCDEMITAIZTP-UHFFFAOYSA-N allylic benzylic alcohol Natural products OCC=CC1=CC=CC=C1 OOCCDEMITAIZTP-UHFFFAOYSA-N 0.000 description 1
- WUOACPNHFRMFPN-UHFFFAOYSA-N alpha-terpineol Chemical compound CC1=CCC(C(C)(C)O)CC1 WUOACPNHFRMFPN-UHFFFAOYSA-N 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 235000010210 aluminium Nutrition 0.000 description 1
- 229940062909 amyl salicylate Drugs 0.000 description 1
- 230000001153 anti-wrinkle effect Effects 0.000 description 1
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 1
- 229960002130 benzoin Drugs 0.000 description 1
- 239000001518 benzyl (E)-3-phenylprop-2-enoate Substances 0.000 description 1
- 229960002903 benzyl benzoate Drugs 0.000 description 1
- NGHOLYJTSCBCGC-QXMHVHEDSA-N benzyl cinnamate Chemical compound C=1C=CC=CC=1\C=C/C(=O)OCC1=CC=CC=C1 NGHOLYJTSCBCGC-QXMHVHEDSA-N 0.000 description 1
- 229940000635 beta-alanine Drugs 0.000 description 1
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 description 1
- 229940067596 butylparaben Drugs 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229960004203 carnitine Drugs 0.000 description 1
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 description 1
- 229940044199 carnosine Drugs 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- SVURIXNDRWRAFU-OGMFBOKVSA-N cedrol Chemical compound C1[C@]23[C@H](C)CC[C@H]3C(C)(C)[C@@H]1[C@@](O)(C)CC2 SVURIXNDRWRAFU-OGMFBOKVSA-N 0.000 description 1
- 229940026455 cedrol Drugs 0.000 description 1
- PCROEXHGMUJCDB-UHFFFAOYSA-N cedrol Natural products CC1CCC2C(C)(C)C3CC(C)(O)CC12C3 PCROEXHGMUJCDB-UHFFFAOYSA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- NGHOLYJTSCBCGC-UHFFFAOYSA-N cis-cinnamic acid benzyl ester Natural products C=1C=CC=CC=1C=CC(=O)OCC1=CC=CC=C1 NGHOLYJTSCBCGC-UHFFFAOYSA-N 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 235000000484 citronellol Nutrition 0.000 description 1
- 239000001926 citrus aurantium l. subsp. bergamia wright et arn. oil Substances 0.000 description 1
- 239000001071 citrus reticulata blanco var. mandarin Substances 0.000 description 1
- 229940071160 cocoate Drugs 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- 229940110767 coenzyme Q10 Drugs 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 229940109239 creatinine Drugs 0.000 description 1
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000000254 damaging effect Effects 0.000 description 1
- SQIFACVGCPWBQZ-UHFFFAOYSA-N delta-terpineol Natural products CC(C)(O)C1CCC(=C)CC1 SQIFACVGCPWBQZ-UHFFFAOYSA-N 0.000 description 1
- 125000001664 diethylamino group Chemical group [H]C([H])([H])C([H])([H])N(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940116365 diethylhexyl syringylidenemalonate Drugs 0.000 description 1
- 229940120503 dihydroxyacetone Drugs 0.000 description 1
- 229940031569 diisopropyl sebacate Drugs 0.000 description 1
- XFKBBSZEQRFVSL-UHFFFAOYSA-N dipropan-2-yl decanedioate Chemical compound CC(C)OC(=O)CCCCCCCCC(=O)OC(C)C XFKBBSZEQRFVSL-UHFFFAOYSA-N 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000009189 diving Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 229960000655 ensulizole Drugs 0.000 description 1
- NYNCZOLNVTXTTP-UHFFFAOYSA-N ethyl 2-(1,3-dioxoisoindol-2-yl)acetate Chemical compound C1=CC=C2C(=O)N(CC(=O)OCC)C(=O)C2=C1 NYNCZOLNVTXTTP-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229940043259 farnesol Drugs 0.000 description 1
- 229930002886 farnesol Natural products 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- 229940113087 geraniol Drugs 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 229940080812 glyceryl caprate Drugs 0.000 description 1
- 229940075529 glyceryl stearate Drugs 0.000 description 1
- 239000001927 guaiacum sanctum l. gum oil Substances 0.000 description 1
- 235000019382 gum benzoic Nutrition 0.000 description 1
- WNLRTRBMVRJNCN-UHFFFAOYSA-N hexanedioic acid Natural products OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- FVYXIJYOAGAUQK-UHFFFAOYSA-N honokiol Chemical compound C1=C(CC=C)C(O)=CC=C1C1=CC(CC=C)=CC=C1O FVYXIJYOAGAUQK-UHFFFAOYSA-N 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 229920006007 hydrogenated polyisobutylene Polymers 0.000 description 1
- WPFVBOQKRVRMJB-UHFFFAOYSA-N hydroxycitronellal Chemical compound O=CCC(C)CCCC(C)(C)O WPFVBOQKRVRMJB-UHFFFAOYSA-N 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229930013032 isoflavonoid Natural products 0.000 description 1
- 150000003817 isoflavonoid derivatives Chemical class 0.000 description 1
- 235000012891 isoflavonoids Nutrition 0.000 description 1
- SVURIXNDRWRAFU-UHFFFAOYSA-N juniperanol Natural products C1C23C(C)CCC3C(C)(C)C1C(O)(C)CC2 SVURIXNDRWRAFU-UHFFFAOYSA-N 0.000 description 1
- 229940001447 lactate Drugs 0.000 description 1
- 150000003893 lactate salts Chemical class 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 description 1
- 239000010501 lemon oil Substances 0.000 description 1
- 235000001510 limonene Nutrition 0.000 description 1
- 229940087305 limonene Drugs 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- 235000019136 lipoic acid Nutrition 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- JPTOCTSNXXKSSN-UHFFFAOYSA-N methylheptenone Chemical compound CCCC=CC(=O)CC JPTOCTSNXXKSSN-UHFFFAOYSA-N 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 239000001627 myristica fragrans houtt. fruit oil Substances 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- SBLKVIQSIHEQOF-UHFFFAOYSA-N octadec-9-enedioic acid Chemical compound OC(=O)CCCCCCCC=CCCCCCCCC(O)=O SBLKVIQSIHEQOF-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N p-hydroxybenzoic acid propyl ester Natural products CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 229940098888 phenethyl benzoate Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 231100000760 phototoxic Toxicity 0.000 description 1
- 235000011765 phytoene Nutrition 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229940061570 polyglyceryl-10 stearate Drugs 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920006254 polymer film Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- RMGVATURDVPNOZ-UHFFFAOYSA-M potassium;hexadecyl hydrogen phosphate Chemical compound [K+].CCCCCCCCCCCCCCCCOP(O)([O-])=O RMGVATURDVPNOZ-UHFFFAOYSA-M 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229940079889 pyrrolidonecarboxylic acid Drugs 0.000 description 1
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical class CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 description 1
- 239000010668 rosemary oil Substances 0.000 description 1
- 229940058206 rosemary oil Drugs 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- 229940045898 sodium stearoyl glutamate Drugs 0.000 description 1
- KDHFCTLPQJQDQI-BDQAORGHSA-M sodium;(4s)-4-amino-5-octadecanoyloxy-5-oxopentanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC(=O)[C@@H](N)CCC([O-])=O KDHFCTLPQJQDQI-BDQAORGHSA-M 0.000 description 1
- LWBVAHQZGAKXPU-BOXHHOBZSA-M sodium;(4s)-4-amino-5-octadecoxy-5-oxopentanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOC(=O)[C@@H](N)CCC([O-])=O LWBVAHQZGAKXPU-BOXHHOBZSA-M 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 229940116411 terpineol Drugs 0.000 description 1
- 229940080258 tetrasodium iminodisuccinate Drugs 0.000 description 1
- GYBINGQBXROMRS-UHFFFAOYSA-J tetrasodium;2-(1,2-dicarboxylatoethylamino)butanedioate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CC(C([O-])=O)NC(C([O-])=O)CC([O-])=O GYBINGQBXROMRS-UHFFFAOYSA-J 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- PJHKBYALYHRYSK-UHFFFAOYSA-N triheptanoin Chemical compound CCCCCCC(=O)OCC(OC(=O)CCCCCC)COC(=O)CCCCCC PJHKBYALYHRYSK-UHFFFAOYSA-N 0.000 description 1
- 229940078561 triheptanoin Drugs 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
- A61K8/0229—Sticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
Die vorliegende Erfindung betrifft eine kosmetische Zubereitung enthaltenda) ein oder mehrere UV-Filter,b) Cetylpalmitat (INCI: Cetyl Palmitate) undc) ein Wachs mit einem Schmelzpunkt von 68-75 °C, wobei das Gewichtsverhältnis von Cetylpalmitat zum Wachs mit einem Schmelzpunkt von 68-75 °C von 0,45 bis 1,5 beträgt, sowie Verfahren und Verwendungen von Cetylpalmitat und Wachsen mit einem Schmelzpunkt von 68-75 °C in kosmetischen Sonnenschutzmitteln.The present invention relates to a cosmetic preparation containing da) one or more UV filters, b) cetyl palmitate (INCI: cetyl palmitate) and c) a wax with a melting point of 68-75 ° C., the weight ratio of cetyl palmitate to wax with a melting point of 68-75 ° C from 0.45 to 1.5, as well as methods and uses of cetyl palmitate and waxes with a melting point of 68-75 ° C in cosmetic sunscreens.
Description
Die vorliegende Erfindung betrifft eine kosmetische Zubereitung enthaltend
- a) ein oder mehrere UV-Filter,
- b) Cetylpalmitat (INCI: Cetyl Palmitate) und
- c) ein Wachs mit einem Schmelzpunkt von 68-75 °C,
- a) one or more UV filters,
- b) cetyl palmitate (INCI: cetyl palmitate) and
- c) a wax with a melting point of 68-75 ° C,
Der Trend weg von der vornehmen Blässe hin zur „gesunden, sportlich braunen Haut“ ist seit Jahren ungebrochen. Um diese zu erzielen setzen die Menschen ihre Haut der Sonnenstrahlung aus, da diese eine Pigmentbildung im Sinne einer Melaninbildung hervorruft. Die ultraviolette Strahlung des Sonnenlichtes hat jedoch auch eine schädigende Wirkung auf die Haut. Neben der akuten Schädigung (Sonnenbrand) treten Langzeitschäden wie ein erhöhtes Risiko an Hautkrebs zu erkranken bei übermäßiger Bestrahlung mit Licht aus dem UVB-Bereich (Wellenlänge: 280-320 nm) auf. Die übermäßige Einwirkung der UVB- und UVA-Strahlung (Wellenlänge: 320-400 nm) führt darüber hinaus zu einer Schwächung der elastischen und kollagenen Fasern des Bindegewebes. Dies führt zu zahlreichen phototoxischen und photoallergischen Reaktionen und hat eine vorzeitige Hautalterung zur Folge.The trend away from the elegant pallor towards "healthy, sporty brown skin" has been going on for years. In order to achieve this, people expose their skin to the sun's radiation, since this causes pigment formation in the sense of melanin formation. However, the ultraviolet radiation from sunlight also has a damaging effect on the skin. In addition to acute damage (sunburn), long-term damage such as an increased risk of developing skin cancer occurs with excessive exposure to light from the UVB range (wavelength: 280-320 nm). The excessive exposure to UVB and UVA radiation (wavelength: 320-400 nm) also leads to a weakening of the elastic and collagen fibers of the connective tissue. This leads to numerous phototoxic and photoallergic reactions and results in premature skin aging.
Zum Schutz der Haut wurde daher eine Reihe von Lichtschutzfiltersubstanzen entwickelt, die in kosmetischen Zubereitungen eingesetzt werden können. Diese UVA- und UVB-Filter sind in den meisten Industrieländern in Form von Positivlisten wie dem Anlage 7 der Kosmetikverordnung zusammengefasst.To protect the skin, a number of light protection filter substances have therefore been developed that can be used in cosmetic preparations. These UVA and UVB filters are summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the Cosmetics Regulation.
Die Vielzahl an kommerziell erhältlichen Sonnenschutzmitteln darf jedoch nicht darüber hinwegtäuschen, dass diese Zubereitungen des Standes der Technik eine Reihe von Nachteilen aufweisen.However, the large number of commercially available sunscreens must not hide the fact that these preparations of the prior art have a number of disadvantages.
Eine weit verbreitete Nutzungsform kosmetischer Sonnenschutzmittel findet rund um den Wassersport statt. Gerne werden die Sonnenschutzmittel in Verbindung mit Strandurlaub, Besuchen in Schwimmbädern, beim Baden, Surfen, Tauchen, Paddeln oder anderen Aktivitäten eingesetzt, bei denen die menschliche Haut mit Wasser in Kontakt kommt.A widespread use of cosmetic sunscreens takes place around water sports. The sunscreens are often used in connection with beach holidays, visits to swimming pools, bathing, surfing, diving, paddling or other activities in which the human skin comes into contact with water.
Bei allen diesen Aktivitäten kommt es für einen umfassenden UV-Schutz darauf an, dass das Sonnenschutzmittel eine gewisse Wasserfestigkeit aufweist und nicht sofort bei Kontakt mit dem Wasser von der Haut abgespült wird.For all of these activities, it is important for comprehensive UV protection that the sunscreen has a certain water resistance and is not rinsed off the skin immediately upon contact with the water.
Zur Erhöhung der Wasserfestigkeit kosmetischer Sonnenschutzmittel werden diesen Zubereitungen in der Regel sogenannte Filmbildner zugesetzt. Bei den Filmbildnern handelt es sich üblicherweise um polymere Verbindungen auf der Basis von Polyacrylaten oder Polyvinylpyrrolidonen, die auf der Haut einen Schutzfilm ausbilden, der das Abwaschen der UV-Filter von der Haut verhindern/verzögern soll.So-called film formers are generally added to these preparations to increase the water resistance of cosmetic sunscreens. The film formers are usually polymeric compounds based on polyacrylates or polyvinylpyrrolidones, which form a protective film on the skin which is intended to prevent / delay the washing of the UV filters from the skin.
Der Einsatz derartiger Filmbildner wird von einer breiten Öffentlichkeit zunehmend kritisch gesehen. Es wird in der öffentlichen Diskussion des Öfteren die Sorge geäußert, polymere Filmbildner können analog dem so genannten „Mikroplastik“ eine Belastung für die Umwelt darstellen. Ob derartige Sorgen berechtigt und naturwissenschaftlich begründet sind, kann im Rahmen der vorliegenden Offenbarung dahingestellt bleiben. Tatsache ist hingegen, dass bei den Kosmetikherstellern und Verbrauchern zunehmend ein Interesse daran besteht, alternative Techniken zur Gewährleistung der Wasserfestigkeit von Sonnenschutzmitteln zu entwickeln.The general public is increasingly critical of the use of such film formers. In the public discussion, there is often concern that polymer film formers, like the so-called “microplastics”, can be a burden on the environment. Whether such concerns are justified and scientifically justified can be left open in the context of the present disclosure. However, the fact is that cosmetics manufacturers and consumers are increasingly interested in developing alternative techniques to ensure the water resistance of sunscreens.
Es war daher die Aufgabe der vorliegenden Erfindung, ein möglichst wasserfestes Sonnenschutzmittel zu entwickeln, bei dem auf den Einsatz von polymeren Filmbildnern (insbesondere solchen auf Basis von Polyacrylaten und Polyvinylpyrrolidonen) weitgehend verzichtet werden kann.It was therefore the object of the present invention to develop a sunscreen which is as waterproof as possible and in which the use of polymeric film formers (in particular those based on polyacrylates and polyvinylpyrrolidones) can largely be dispensed with.
Überraschend gelöst wird die Aufgabe durch eine kosmetische Zubereitung enthaltend
- a) ein oder mehrere UV-Filter,
- b) Cetylpalmitat (INCI: Cetyl Palmitate) und
- c) ein Wachs mit einem Schmelzpunkt von 68-75 °C,
- a) one or more UV filters,
- b) cetyl palmitate (INCI: cetyl palmitate) and
- c) a wax with a melting point of 68-75 ° C,
In den Untersuchungen, die der vorliegenden Erfindung zugrunde liegen, wurde festgestellt, dass, entgegen den Erwartungen, bei Kontakt mit Wasser der Lichtschutzfaktor SPF auf der mit der erfindungsgemäßen Zubereitung behandelten Haut nicht etwa abnimmt sondern vielmehr noch ansteigt. Dieser bei Kontakt mit Wasser ermittelte Lichtschutzfaktor, auch SPW genannt, wird nach der folgenden Methode bestimmt:
- In Vivo Determination of Sun Protection International Standard
ISO 24444 PA 2005
- In Vivo Determination of Sun Protection International Standard
ISO 24444 PA 2005
Erfindungsgemäß ist daher auch ein Verfahren zur Erhöhung des Lichtschutzfaktors SPF beim Baden in Wasser, dadurch gekennzeichnet, dass man vor dem Baden ein Sonnenschutzmittel enthaltend
- a) Cetylpalmitat (INCI: Cetyl Palmitate) und
- b) ein Wachs mit einem Schmelzpunkt von 68-75 °C,
in einem Gewichtsverhältnis von Cetylpalmitat zum Wachs mit einem Schmelzpunkt von 68-75 °C von 0,45 bis 1,5 auf die Haut aufträgt.According to the invention is therefore also a method for increasing the SPF when bathing in water, characterized in that it contains a sunscreen before bathing
- a) Cetyl Palmitate (INCI: Cetyl Palmitate) and
- b) a wax with a melting point of 68-75 ° C,
in a weight ratio of cetyl palmitate to wax with a melting point of 68-75 ° C from 0.45 to 1.5 to the skin.
Erfindungsgemäß ist ferner die Verwendung einer Kombination aus
- a) Cetylpalmitat (INCI: Cetyl Palmitate) und
- b) ein Wachs mit einem Schmelzpunkt von 68-75 °C,
sowie
die Verwendung einer Kombination aus
- a) Cetylpalmitat (INCI: Cetyl Palmitate) und
- b) ein Wachs mit einem Schmelzpunkt von 68-75 °C,
- a) Cetyl Palmitate (INCI: Cetyl Palmitate) and
- b) a wax with a melting point of 68-75 ° C,
such as
the use of a combination of
- a) Cetyl Palmitate (INCI: Cetyl Palmitate) and
- b) a wax with a melting point of 68-75 ° C,
Die Formulierungen „erfindungsgemäß“, „erfindungsgemäß vorteilhaft“ etc. beziehen sich im Rahmen der vorliegenden Offenbarung immer auf das erfindungsgemäße Sonnenschutzmittel, die erfindungsgemäßen Verwendungen und das erfindungsgemäße Verfahren, wenn es im Einzelfall nicht anders beschrieben wird. Die Schmelzpunkte werden bei Normaldruck (1,013 bar) bestimmt. Als UV-Filter gelten erfindungsgemäß alle Substanzen, die in der Verordnung (EU) Nr. 866/2014 und der Verordnung Nr. 1223/2009 der EU Kommission in der Anlage VI als UV-Filter aufgelistet sind.Within the scope of the present disclosure, the formulations “according to the invention”, “according to the invention advantageously” etc. always refer to the sunscreen according to the invention, the uses according to the invention and the method according to the invention, unless it is described differently in the individual case. The melting points are determined at normal pressure (1.013 bar). According to the invention, all substances are listed as UV filters which are listed in Annex VI to Regulation (EU) No. 866/2014 and Regulation No. 1223/2009 of the EU Commission as UV filters.
Es ist erfindungsgemäß vorteilhaft, wenn als Wachs mit einem Schmelzpunkt von 68-75 °C Sonnenblumenwachs (INCI: Heliantus Annuus Seed Cera), Phytowax (INCI: Castor Hydrogenated Cetyl Castor Esters oder Hydrogenated Behenyl Castor Esters) Candelilla Wax (INCI: Candelilla Wax), Cosmetik Wax A4 (INCI: Hydrogenated Vegetable Oil) oder Syncrowax (INCI: C18-C36 Acid Glycol Ester) eingesetzt werden.It is advantageous according to the invention if, as a wax with a melting point of 68-75 ° C., sunflower wax (INCI: Heliantus Annuus Seed Cera), Phytowax (INCI: Castor Hydrogenated Cetyl Castor Esters or Hydrogenated Behenyl Castor Esters) Candelilla Wax (INCI: Candelilla Wax) , Cosmetic Wax A4 (INCI: Hydrogenated Vegetable Oil) or Syncrowax (INCI: C18-C36 Acid Glycol Ester).
Erfindungsgemäß besonders bevorzugt ist dabei der Einsatz von Sonnenblumenwachs (INCI: Heliantus Annuus Seed Cera).According to the invention, the use of sunflower wax (INCI: Heliantus Annuus Seed Cera) is particularly preferred.
Erfindungsgemäß vorteilhafte Ausführungsformen der vorliegenden Erfindung sind dadurch gekennzeichnet, dass die Zubereitung einen oder mehrere UV-Filter gewählt aus der Gruppe der Verbindungen 4-(tert.-Butyl)-4'-methoxydibenzoylmethan (INCI Butyl Methoxydibenzoylmethane), (2-[-4-(Diethylamino)-2-hydroxybenzoyl] Benzoesäurehexylester (INCI: Diethylamino Hydroxybenzoyl Hexyl Benzoate) und 2,4-Bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazin (INCI Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine) enthält.Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more UV filters selected from the group of the compounds 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane), (2 - [- 4 - (Diethylamino) -2-hydroxybenzoyl] hexanoate (INCI: Diethylamino Hydroxybenzoyl Hexyl Benzoate) and 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6- (4- contains methoxyphenyl) -1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl triazine).
Enthält die Zubereitung 4-(tert.-Butyl)-4'-methoxydibenzoylmethan (INCI Butyl Methoxydibenzoylmethane), so beträgt die erfindungsgemäß vorteilhafte 1 bis 5% Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung.If the preparation contains 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane), the advantageous amount according to the invention is 1 to 5% by weight, based on the total weight of the preparation.
Enthält die Zubereitung (2-[-4-(Diethylamino)-2-hydroxybenzoyl] Benzoesäurehexylester (INCI: Diethylamino Hydroxybenzoyl Hexyl Benzoate), so beträgt die erfindungsgemäß vorteilhafte Einsatzkonzentration von 1 bis 9 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung. If the preparation contains (2 - [- 4- (diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester (INCI: diethylamino hydroxybenzoyl hexyl benzoate), the advantageous use concentration according to the invention is from 1 to 9% by weight, based on the total weight of the preparation.
Enthält die Zubereitung 2,4-Bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazin (INCI Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine), so beträgt die erfindungsgemäß vorteilhafte Einsatzkonzentration von 0,5 bis Gew. 4,5% bezogen auf das Gesamtgewicht der Zubereitung.Contains the preparation 2,4-bis - {[4- (2-ethylhexyloxy) -2-hydroxy] phenyl} -6- (4-methoxyphenyl) -1,3,5-triazine (INCI bis-ethylhexyloxyphenol methoxyphenyl Triazines), the advantageous use concentration according to the invention is from 0.5 to 4.5% based on the total weight of the preparation.
Ferner sind erfindungsgemäß vorteilhafte Ausführungsformen dadurch gekennzeichnet, dass sie einen oder mehrere UV-Filter, gewählt aus der Gruppe der Verbindungen 2-Phenylbenzimidazol-5-sulfonsäuresalze; Phenylen-1,4-bis-(2-benzimidazyl)-3,3'-5,5'-tetrasulfonsäuresalze; 1,4-di(2-oxo-10-Sulfo-3-bornylidenmethyl)-Benzol und dessen Salze; 4-(2-Oxo-3-bornylidenmethyl)benzolsulfonsäuresalze; 2-Methyl-5-(2-oxo-3-bornyliden-methyl)sulfonsäuresalze; 2,2'-Methylen-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)-phenol); 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]-phenol; Ethylhexylsalicylat; Terephthalidendicamphersulfonsäuresalze; 2-Ethylhexyl-2-cyano-3,3-diphenylacrylat; 4-(Dimethylamino)benzoesäure-amylester; 4-Methoxybenzalmalon-säuredi(2-ethylhexyl)ester; 4-Methoxyzimtsäureisoamylester; 2-Hydroxy-4-methoxy-4'-methylbenzophenon; 2,2'-Dihydroxy-4-methoxybenzophenon; Homomenthylsalicylat; 2-Ethylhexyl-2-hydroxybenzoat; Dimethicodiethylbenzalmalonat; 3-(4-(2,2-bis Ethoxycarbonylvinyl)-phenoxy)propenyl)-meth-oxysiloxan / Dimethylsiloxan - Copolymer; Dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone); 2,4-bis-[5-1(dimethylpropyl)benzoxazol-2-yl-(4-phenyl)-imino]-6-(2-ethylhexyl)-imino-1,3,5-triazin mit der (CAS Nr. 288254-16-0); 4,4',4"-(1,3,5-Triazin-2,4,6-triyltriimino)-tris-benzoësäure-tris(2-ethylhexylester) (auch: 2,4,6-Tris-[anilino-(p-carbo-2'-ethyl-1'-hexyloxy)]-1,3,5-triazin (INCI: Ethylhexyl Triazone); 2,4,6-Tribiphenyl-4-yl-1,3,5-triazin; Merocyanine; Piperazinderivate;Titandioxid; Zinkoxid, enthalten.Furthermore, advantageous embodiments according to the invention are characterized in that they have one or more UV filters selected from the group of the compounds 2-phenylbenzimidazole-5-sulfonic acid salts; Phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid salts; 1,4-di (2-oxo-10-sulfo-3-bornylidenemethyl) benzene and its salts; 4- (2-oxo-3-bornylidenemethyl) benzenesulfonic acid salts; 2-methyl-5- (2-oxo-3-bornylidene-methyl) sulfonic acid salts; 2,2'-methylene-bis- (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol); 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] phenol ; Ethylhexyl salicylate; Terephthalic dicamphersulfonic acid salts; 2-ethylhexyl-2-cyano-3,3-diphenyl acrylate; 4- (dimethylamino) benzoic acid amyl ester; 4-methoxybenzalmalonic acid di (2-ethylhexyl) ester; 4-methoxycinnamic acid isoamyl ester; 2-hydroxy-4-methoxy-4'-methylbenzophenone; 2,2'-dihydroxy-4-methoxybenzophenone; Homomenthyl salicylate; 2-ethylhexyl 2-hydroxybenzoate; Dimethicodiethylbenzalmalonate; 3- (4- (2,2-bis ethoxycarbonylvinyl) phenoxy) propenyl) meth oxysiloxane / dimethylsiloxane copolymer; Dioctylbutylamidotriazon (INCI: diethylhexyl butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) imino] -6- (2-ethylhexyl) imino-1,3,5-triazine with the (CAS No. 288254-16-0); 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester) (also: 2,4,6-tris [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: ethylhexyl triazone); 2,4,6-tribiphenyl-4-yl-1,3,5-triazine ; Merocyanines; piperazine derivatives; titanium dioxide; zinc oxide.
Dabei ist insbesondere der Einsatz von Phenylbenzimidazol-5-sulfonsäuresalzen, Ethylhexylsalicylat, Homomenthylsalicylat, 2-Ethylhexyl-2-cyano-3,3-diphenylacrylat, Dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone), 4,4',4"-(1,3,5-Triazin-2,4,6-triyltriimino)-tris-benzoësäure-tris(2-ethylhexylester) (INCI: Ethylhexyl Triazone), Titandioxid. erfindungsgemäß bevorzugt. Erfindungsgemäß besonders bevorzugt sind die UV-Filter Phenylbenzimidazol-5-sulfonsäuresalzen, Ethylhexylsalicylat, Dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone), 4,4',4"-(1,3,5-Triazin-2,4,6-triyltriimino)-tris-benzoesäure-tris-(2-ethylhexylester) (INCI: Ethylhexyl Triazone).In particular, the use of phenylbenzimidazole-5-sulfonic acid salts, ethylhexyl salicylate, homomenthyl salicylate, 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, dioctylbutylamidotriazone (INCI: diethylhexyl butamidotriazone), 4,4 ', 4 "-, 4,4', 4" - 3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester) (INCI: ethylhexyl triazone), titanium dioxide preferred according to the invention, the UV filters phenylbenzimidazole-5-sulfonic acid salts being particularly preferred according to the invention , Ethylhexyl salicylate, dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone), 4,4 ', 4 "- (1,3,5-triazine-2,4,6-triyltriimino) -tris-benzoic acid-tris- (2-ethylhexyl ester) ( INCI: ethylhexyl triazone).
Die erfindungsgemäß bevorzugten Einsatzkonzentrationen für Phenylbenzimidazol-5-sulfonsäuresalze beträgt von 0,5 bis 4 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung, die bevorzugte Einsatzkonzentration für Ethylhexylsalicylat beträgt von 0,5 bis 5 Gew.-%, bezogen auf das Gesamtgewicht.The preferred use concentrations according to the invention for phenylbenzimidazole-5-sulfonic acid salts are from 0.5 to 4% by weight, based on the total weight of the preparation, the preferred use concentration for ethylhexyl salicylate is from 0.5 to 5% by weight, based on the total weight .
Es ist vorteilhaft im Sinne der vorliegenden Erfindung, wenn die Zubereitung einen oder mehrere UV-Filter a) in einer Gesamtkonzentration von 1 bis 30 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.For the purposes of the present invention, it is advantageous if the preparation contains one or more UV filters a) in a total concentration of 1 to 30% by weight, based on the total weight of the preparation.
Die erfindungsgemäße Zubereitung kann erfindungsgemäß vorteilhaft in unterschiedlichen Produktformen vorliegen.The preparation according to the invention can advantageously be present in different product forms according to the invention.
In einer ersten vorteilhaften Ausführungsform liegt die Zubereitung in Form eines Stiftes vor. In a first advantageous embodiment, the preparation is in the form of a stick.
In diesem Fall ist die erfindungsgemäß vorteilhafte Ausführungsform dadurch gekennzeichnet, dass die Stiftformulierung
- b) Cetylpalmitat (INCI: Cetyl Palmitate) in einer Konzentration von 0,5 bis 8 Gew.-% und
- c) ein Wachs mit einem Schmelzpunkt von 68-75 °C in einer Konzentration von 0,2 bis 8 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Zubereitung, enthält.
- b) cetyl palmitate (INCI: cetyl palmitate) in a concentration of 0.5 to 8% by weight and
- c) a wax with a melting point of 68-75 ° C in a concentration of 0.2 to 8 wt .-%, based on the total weight of the preparation.
Erfindungsgemäß vorteilhafte Stiftformulierungen sind ferner dadurch gekennzeichnet, dass die Zubereitungen Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate und/oder Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate enthalten.Stick formulations advantageous according to the invention are further characterized in that the preparations contain diisostearoyl polyglyceryl-3 dimer dilinoleates and / or polyglyceryl-4 diisostearates / polyhydroxystearates / sebacates.
Die erfindungsgemäß vorteilhaften Einsatzkonzentrationen für Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate betragen dabei von 0,5 bis 3,0 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung.The advantageous use concentrations according to the invention for diisostearoyl polyglyceryl-3 dimer dilinoleates are from 0.5 to 3.0% by weight, based on the total weight of the preparation.
Die erfindungsgemäß vorteilhaften Einsatzkonzentrationen für Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate betragen dabei von 0,5 bis 3,5 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung. The advantageous use concentrations according to the invention for polyglyceryl-4 diisostearates / polyhydroxystearates / sebacates are from 0.5 to 3.5% by weight, based on the total weight of the preparation.
In den stiftförmigen Zubereitungen lassen sich erfindungsgemäß bevorzugt die UV-Filter Ethylhexylsalicylat, Homomenthylsalicylat, 2-Ethylhexyl-2-cyano-3,3-diphenylacrylat und 4-(tert.-Butyl)-4'-methoxydibenzoylmethan (INCI Butyl Methoxydibenzoylmethane) einarbeiten.According to the invention, the UV filters ethylhexyl salicylate, homomenthyl salicylate, 2-ethylhexyl-2-cyano-3,3-diphenylacrylate and 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) can preferably be incorporated into the stick-like preparations.
Die stiftförmigen Zubereitungen enthalten erfindungsgemäß vorteilhaft Glycerylcaprylate und/oder Glycerin. Sie können bis zu 52 Gew.-% Wasser enthalten.According to the invention, the stick-like preparations advantageously contain glyceryl caprylates and / or glycerin. They can contain up to 52% by weight of water.
In einer zweiten vorteilhaften Ausführungsform kann die Zubereitung in Form einer Emulsion vorliegen. In einem solchen Falle ist es erfindungsgemäß von Vorteil, wenn die Emulsion
- b) Cetylpalmitat (INCI: Cetyl Palmitate) in einer Konzentration von 1,5 bis 6,5 Gew.-% und
- c) ein Wachs mit einem Schmelzpunkt von 68-75 °C in einer Konzentration von 1 bis 6,5 Gew.- %, jeweils bezogen auf das Gesamtgewicht der Zubereitung, enthält.
- b) cetyl palmitate (INCI: cetyl palmitate) in a concentration of 1.5 to 6.5 wt .-% and
- c) a wax with a melting point of 68-75 ° C in a concentration of 1 to 6.5% by weight, based in each case on the total weight of the preparation.
Der erfindungsgemäß vorteilhafte Emulsionstyp ist dabei die O/W-Emulsion und W/O Liegt die erfindungsgemäße Zubereitung in Form einer O/W-Emulsion vor, so ist sie erfindungsgemäß vorteilhaft dadurch gekennzeichnet, dass die Zubereitung einen oder mehrere O/W-Emulgatoren gewählt aus der Gruppe der Verbindungen Glycerylstearatcitrat, Glycerylstearat (selbstemulgierend), Stearinsäure, Stearatsalze, Polyglyceryl-3-methylglycosedistearat, Natriumcetearylsulfat, Kaliumcetylphosphat, Polyglyceryl-10 Stearate , Natriumstearylglutamat, enthält.The type of emulsion advantageous according to the invention is the O / W emulsion and W / O. If the preparation according to the invention is in the form of an O / W emulsion, it is advantageously characterized according to the invention in that the preparation selects one or more O / W emulsifiers from the group of compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, sodium cetearyl sulfate, potassium cetyl phosphate, polyglyceryl 10 stearate, sodium stearyl glutamate.
Liegt die erfindungsgemäße Zubereitung in Form einer W/O -Emulsion vor, so ist sie erfindungsgemäß vorteilhaft dadurch gekennzeichnet, dass die Zubereitung einen oder mehrere W/O-Emulgatoren gewählt aus der Gruppe der Verbindungen Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Polyglyceryl-3 Polyricinoleate und/oder Polyglyceryl-2 Sesquioleate enthält.If the preparation according to the invention is in the form of a W / O emulsion, it is advantageously characterized according to the invention in that the preparation comprises one or more W / O emulsifiers selected from the group of the compounds diisostearoyl polyglyceryl-3 dimer dilinoleates, polyglyceryl-4 diisostearates / Polyhydroxystearate / Sebacate, Polyglyceryl-3 Polyricinoleate and / or Polyglyceryl-2 Sesquioleate contains.
In einer dritten vorteilhaften Ausführungsform kann die Zubereitung in Form einer alkoholischen Zubereitung vorliegen. Die erfindungsgemäß bevorzugte Ausführungsform ist dabei das alkoholische Spray.In a third advantageous embodiment, the preparation can be in the form of an alcoholic preparation. The preferred embodiment according to the invention is the alcoholic spray.
Die alkoholische Zubereitung enthält erfindungsgemäß vorteilhaft
- b) Cetylpalmitat (INCI: Cetyl Palmitate) in einer Konzentration von 0,1 bis 5 Gew.-% und
- c) ein Wachs mit einem Schmelzpunkt von 68-75 °C in einer Konzentration von 0,1 bis 6% Gew.-%, jeweils bezogen auf das Gesamtgewicht der Zubereitung.
- b) cetyl palmitate (INCI: cetyl palmitate) in a concentration of 0.1 to 5% by weight and
- c) a wax with a melting point of 68-75 ° C in a concentration of 0.1 to 6% by weight, each based on the total weight of the preparation.
Als „ethanolische Zubereitung“ wird im Rahmen der vorliegenden Erfindung ein Sonnenschutzmittel verstanden, dass mindestens 10 Gewichts-% Ethanol, bezogen auf das Gesamtgewicht der Zubereitung, enthält. Erfindungsgemäß bevorzugt enthält ein solches ethanolisches Sonnenschutzmittel von 20 bis 75 Gewichts-% Ethanol und besonders bevorzugt von 25 bis 70 Gewichts-% Ethanol, jeweils bezogen auf das Gesamtgewicht der Zubereitung.In the context of the present invention, “ethanolic preparation” is understood to mean a sunscreen that contains at least 10% by weight of ethanol, based on the total weight of the preparation. According to the invention, such an ethanolic sunscreen preferably contains from 20 to 75% by weight of ethanol and particularly preferably from 25 to 70% by weight of ethanol, in each case based on the total weight of the preparation.
Vorteilhafte Ausführungsformen im Sinne der vorliegenden Erfindung sind dadurch gekennzeichnet, dass die Zubereitung Phenoxyethanol, Ethylhexylglycerin und/oder 4-Hydroxyacetophenon enthält.Advantageous embodiments in the sense of the present invention are characterized in that the preparation contains phenoxyethanol, ethylhexylglycerol and / or 4-hydroxyacetophenone.
Ferner ist es erfindungsgemäß von Vorteil, wenn die Zubereitung ein oder mehrere Alkandiole aus der Gruppe der Verbindungen 1,2-Pentandiol, 1,2-Hexandiol, 1,2-Octandiol, 1,2-Decandiol, 2-Methyl-1,3-propandiol enthält.It is also advantageous according to the invention if the preparation comprises one or more alkanediols from the group of the compounds 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol, 2-methyl-1,3 -propanediol contains.
Außerdem ist es erfindungsgemäß vorteilhaft, wenn die Zubereitung frei ist von 3-(4-Methylbenzyliden)-campher, 2-Hydroxy-4-methoxybenzophenon (INCI: Oxybenzon), 4-Methoxyzimtsäure-2-ethylhexylester (INCI Octylmethoxycinnamate), Parabenen (insbesondere Propyl- und Butylparaben), Methylisothiazolinon, Chlormethyl-isothiazolinon und DMDM-Hydantoin, Polyethylenglycolethern oder Polyethylenglycolestern.It is also advantageous according to the invention if the preparation is free from 3- (4-methylbenzylidene) camphor, 2-hydroxy-4-methoxybenzophenone (INCI: oxybenzone), 4-methoxycinnamic acid-2-ethylhexyl ester (INCI octylmethoxycinnamate), parabens (in particular Propyl and butyl paraben), methyl isothiazolinone, chloromethyl isothiazolinone and DMDM hydantoin, polyethylene glycol ethers or polyethylene glycol esters.
Erfindungsgemäß vorteilhafte Ausführungsformen der vorliegenden Erfindung sind dadurch gekennzeichnet, dass die Zubereitung eine oder mehrere Verbindungen gewählt aus der Gruppe der Verbindungen alpha-Liponsäure, Folsäure, Phytoen, D-Biotin, Coenzym Q10, alpha-Glucosylrutin, Carnitin, Carnosin, natürliche und/oder synthetische Isoflavonoide, Flavonoide, Kreatin, Kreatinin, Taurin, β-Alanin, Panthenol, Magnolol, Honokiol, Tocopherylacetat, Dihydroxyaceton; 8-Hexadecen-1,16-dicarbonsäure, Glycerylglycose, (2-Hydroxyethyl)harnstoff, Vitamin E bzw. seine Derivate, Hyaluronsäure und/oder deren Salze und/oder Licochalcon A enthält.Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, β-alanine, panthenol, magnolol, honokiol, tocopheryl acetate, dihydroxyacetone; Contains 8-hexadecen-1,16-dicarboxylic acid, glycerylglycose, (2-hydroxyethyl) urea, vitamin E or its derivatives, hyaluronic acid and / or its salts and / or licochalcon A.
Die erfindungsgemäße Zubereitung kann vorteilhaft Feuchthaltemittel enthalten. Als Feuchthaltemittel (Moisturizer) werden Stoffe oder Stoffgemische bezeichnet, welche kosmetischen Zubereitungen die Eigenschaft verleihen, nach dem Auftragen bzw. Verteilen auf der Hautoberfläche die Feuchtigkeitsabgabe der Hornschicht (auch transepidermal water loss (TEWL) genannt) zu reduzieren und/oder die Hydratation der Hornschicht positiv zu beeinflussen.The preparation according to the invention can advantageously contain humectants. Moisturizers are substances or mixtures of substances that give cosmetic preparations the property of reducing the release of moisture from the horny layer (also called transepidermal water loss (TEWL)) and / or hydrating the horny layer after application or distribution on the skin surface to positively influence.
Vorteilhafte Feuchthaltemittel (Moisturizer) im Sinne der vorliegenden Erfindung sind beispielsweise Glycerin, Milchsäure und/oder Lactate, insbesondere Natriumlactat, Butylenglykol, Propylenglykol, Biosaccaride Gum-1, Glycine Soja, Ethylhexyloxyglycerin, Pyrrolidoncarbonsäure und Harnstoff. Ferner ist es insbesondere von Vorteil, polymere Moisturizer aus der Gruppe der wasserlöslichen und/oder in Wasser quellbaren und/oder mit Hilfe von Wasser gelierbaren Polysaccharide zu verwenden. Insbesondere vorteilhaft sind beispielsweise Hyaluronsäure, Chitosan und/oder ein fucosereiches Polysaccharid, welches in den
Die erfindungsgemäßen kosmetischen Zubereitungen können ferner vorteilhaft, wenngleich nicht zwingend, Füllstoffe enthalten, welche z. B. die sensorischen und kosmetischen Eigenschaften der Formulierungen weiter verbessern und beispielsweise ein samtiges oder seidiges Hautgefühl hervorrufen oder verstärken. Vorteilhafte Füllstoffe im Sinne der vorliegenden Erfindung sind Stärke und Stärkederivate (wie z. B. Tapiocastärke, Distärkephosphat, Aluminium- bzw. Natrium-Stärke Octenylsuccinat und dergleichen), Pigmente, die weder hauptsächlich UV-Filter- noch färbende Wirkung haben (wie z. B. Bornitrid etc.) und/oder Aerosile® (CAS-Nr. 7631-86-9) und /oder Talkum und/oder Polyethylen, Nylon.The cosmetic preparations according to the invention can furthermore advantageously, although not necessarily, contain fillers which, for. B. further improve the sensory and cosmetic properties of the formulations and, for example, cause or intensify a velvety or silky feeling on the skin. Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as tapioca starch, distarch phosphate, aluminum or sodium starch, octenyl succinate and the like), pigments which have neither mainly UV filter nor coloring effects (such as e.g. B. boron nitride etc.) and / or Aerosile ® (CAS No. 7631-86-9) and / or talc and / or polyethylene, nylon.
Es ist erfindungsgemäß bevorzugt, wenn die erfindungsgemäße Zubereitung Tapiocastärke und/oder Distärkephosphat enthält.It is preferred according to the invention if the preparation according to the invention contains tapioca starch and / or distarch phosphate.
Erfindungsgemäß vorteilhafte Ausführungsformen der vorliegenden Erfindung sind dadurch gekennzeichnet, dass die Zubereitung ein oder mehrere Öle gewählt aus der Gruppe der Verbindungen Butylene Glycol Dicaprylat/Dicaprat, Phenethyl Benzoat, C12-15 Alkyl Benzoat, Dibutyladipat; Diisopropylsebacate, Dicaprylylcarbonat, Di-C12-13 Alkyl Tartrate, Butyloctyl Salicylate, Diethylhexyl Syringylidene Malonate, Hydragenated Castor Oil Dimerate, Triheptanoin, C12-13 Alkyl Lactate, C16-17 Alkyl Benzoate, Propylheptyl Caprylate, Caprylic/Capric Triglyceride, Diethylhexyl 2,6-Naphthalate, Octyldodecanol, Caprylic/Capric Triglyceride, Ethylhexyl Cocoate, enthält.Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation has one or more oils selected from the group of the compounds butylene glycol dicaprylate / dicaprate, phenethyl benzoate, C12-15 alkyl benzoate, dibutyl adipate; Diisopropyl sebacate, dicaprylyl carbonate, di-C12-13 alkyl tartrate, butyl octyl salicylate, diethylhexyl syringylidene malonate, hydragenated castor oil dimerate, triheptanoin, C12-13 alkyl lactate, C16-17 alkyl benzoate, propylheptyl caprylric, tricyllic, triglylic, triglylic, triglylic, caprylic, triglylic, caprylic -Naphthalates, octyldodecanol, caprylic / capric triglycerides, ethylhexyl cocoate, contains.
Dabei ist es erfindungsgemäß bevorzugt, wenn die Zubereitung Dibutyladipat, Dicaprylylcarbonat, Butylene Glycol Dicaprylat/Dicaprat und/oder C12-C15 Alkylbenzoat enthält.It is preferred according to the invention if the preparation contains dibutyl adipate, dicaprylyl carbonate, butylene glycol dicaprylate / dicaprate and / or C12-C15 alkyl benzoate.
Die Wasserphase der erfindungsgemäßen Zubereitungen kann vorteilhaft übliche kosmetische Hilfsstoffe enthalten, wie beispielsweise Alkohole, insbesondere solche niedriger C-Zahl, vorzugsweise Ethanol und/oder Isopropanol oder Polyole niedriger C-Zahl sowie deren Ether, vorzugsweise Propylenglykol, Glycerin, Elektrolyte, Selbstbräuner sowie insbesondere ein oder mehrere Verdickungsmittel, welches oder welche vorteilhaft gewählt werden können aus der Gruppe Siliciumdioxid, Aluminiumsilikate, Polysaccharide bzw. deren Derivate, z. B. Hyaluronsäure, Xanthangummi, Hydroxypropylmethylcellulose.The water phase of the preparations according to the invention can advantageously contain customary cosmetic auxiliaries, such as, for example, alcohols, in particular those having a low C number, preferably ethanol and / or isopropanol or polyols having a low C number, and also their ethers, preferably propylene glycol, glycerol, electrolytes, self-tanners and in particular or more thickeners, which one or which can advantageously be selected from the group consisting of silicon dioxide, aluminum silicates, polysaccharides or their derivatives, e.g. B. hyaluronic acid, xanthan gum, hydroxypropylmethyl cellulose.
Es ist ferner vorteilhaft im Sinne der vorliegenden Erfindung, wenn die erfindungsgemäße Zubereitung einen oder mehrere Parfümstoffe gewählt aus der Gruppe der Verbindungen Limonen, Citral, Linalool, alpha-Isomethylionon, Geraniol, Citronellol, 2-Isobutyl-4-hydroxy-4-methyltetrahydropyran, 2-tert-Pentylcyclohexylacetat, 3-Methyl-5-phenyl-1-pentanol, 7-Acetyl-1,1,3,4,4,6-hexamethyltetralin, Adipinsäurediester, alpha-Amylcinnamaldehyd, Alpha-Methylionon, Amyl C Butylphenylmethylpropionalcinnamal, Amylsalicylat, Amylcinnamylalkohol, Anisalkohol, Benzoin, Benzylalkohol, Benzylbenzoat, Benzylcinnamat, Benzylsalicylat, Bergamotöl, bitteres Orangenöl, Butylphenylmethylpropioal, Cardamomöl, Cedrol, Cinnamal, Cinnamylalkohol, Citronellylmethylcrotonat, Citronenöl, Coumarin, Diethylsuccinat, Ethyllinalool, Eugenol, Evernia Furfuracea Extract, Evernia Prunastri Extract, Farnesol, Guajakholzöl, Hexylcinnamal, Hexylsalicylat, Hydroxycitronellal, Lavendelöl, Lemonenöl, Linaylacetat, Mandarinenöl, Menthyl PCA, Methylheptenon, Muskatnussöl, Rosmarinöl, süßes Orangenöl, Terpineol, Tonkabohnenöl, Triethylcitrat und/oder Vanillin enthält.It is also advantageous in the context of the present invention if the preparation according to the invention is selected from the group of the compounds limonene, citral, linalool, alpha-isomethylionone, geraniol, citronellol, 2-isobutyl-4-hydroxy-4-methyltetrahydropyran, 2-tert-pentylcyclohexyl acetate, 3-methyl-5-phenyl-1-pentanol, 7-acetyl-1,1,3,4,4,6-hexamethyltetralin, adipic acid diester, alpha-amylcinnamaldehyde, alpha-methylionone, amyl C butylphenylmethylpropionalcinnamal, Amyl salicylate, amyl cinnamyl alcohol, anise alcohol, benzoin, benzyl alcohol, benzyl benzoate, benzyl cinnamate, benzyl salicylate, bergamot oil, bitter orange oil, butylphenylmethylpropioal, cardamomoline oil, cedrol, cinnamal, cinnamyl alcohol, citotonatoloalolinolethyl, citronatolinolinolethyl, citronatoluronol , Farnesol, guaiac wood oil, hexylcinnamal, hexylsalicylate, hydroxycitronellal, Contains lavender oil, lemon oil, linaylacetate, mandarin oil, menthyl PCA, methylheptenone, nutmeg oil, rosemary oil, sweet orange oil, terpineol, tonka bean oil, triethyl citrate and / or vanillin.
Darüber hinaus können die erfindungsgemäßen Zubereitungen die für kosmetische Sonnenschutzmittel üblichen Inhaltsstoffe in den üblichen Einsatzkonzentrationen enthalten.In addition, the preparations according to the invention can contain the usual ingredients for cosmetic sunscreens in the usual use concentrations.
Der erfindungsgemäße Effekt konnte mit dem folgenden Vergleichsversuch belegt werden. Es wurden die folgenden Rezepturen hergestellt.
Phase 1 und 2 getrennt auf 80-90°C erhitzen, wobei darauf zu achten ist das in Phase 1 vor der Weiterverarbeitung alle Komponenten komplett aufgeschmolzen sind und in Phase 2 alle Komponenten gelöst sind.
Die Phasenvereinigung findet bei 77-80°C unter Rühren statt und es wird je nach Ansatzgröße zwischen 1 bis 5min homogenisiert. Nach dem Homogenisieren wird auf 68-75° gekühlt und in geeignete Behältnisse abgefüllt.Heat phases 1 and 2 separately to 80-90 ° C, taking care that in phase 1 all components are completely melted and in phase 2 all components are dissolved.
The phase combination takes place at 77-80 ° C with stirring and, depending on the batch size, it is homogenized between 1 to 5 minutes. After homogenization, the mixture is cooled to 68-75 ° and filled into suitable containers.
BeispieleExamples
Die nachfolgenden Beispiele sollen die vorliegende Erfindung verdeutlichen, ohne sie einzuschränken. Alle Mengenangaben, Anteile und Prozentanteile sind, soweit nicht anders angegeben, auf das Gewicht und die Gesamtmenge bzw. auf das Gesamtgewicht der Zubereitungen bezogen.
ZITATE ENTHALTEN IN DER BESCHREIBUNG QUOTES INCLUDE IN THE DESCRIPTION
Diese Liste der vom Anmelder aufgeführten Dokumente wurde automatisiert erzeugt und ist ausschließlich zur besseren Information des Lesers aufgenommen. Die Liste ist nicht Bestandteil der deutschen Patent- bzw. Gebrauchsmusteranmeldung. Das DPMA übernimmt keinerlei Haftung für etwaige Fehler oder Auslassungen.This list of documents listed by the applicant has been generated automatically and is only included for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.
Zitierte Nicht-PatentliteraturNon-patent literature cited
- ISO 24444 [0011]ISO 24444 [0011]
- PA 2005 [0011]PA 2005 [0011]
- Chemical Abstracts unter der Registraturnummer 178463-23-5 [0044]Chemical Abstracts under registration number 178463-23-5 [0044]
Claims (17)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102018217130.0A DE102018217130A1 (en) | 2018-10-08 | 2018-10-08 | Sunscreen with a combination of waxes and cetyl palmitate |
| PCT/EP2019/076212 WO2020074272A1 (en) | 2018-10-08 | 2019-09-27 | Sunscreen with a combination of waxes and cetyl palmitate |
| EP19783241.3A EP3863597A1 (en) | 2018-10-08 | 2019-09-27 | Sunscreen with a combination of waxes and cetyl palmitate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102018217130.0A DE102018217130A1 (en) | 2018-10-08 | 2018-10-08 | Sunscreen with a combination of waxes and cetyl palmitate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102018217130A1 true DE102018217130A1 (en) | 2020-04-09 |
Family
ID=68159080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102018217130.0A Withdrawn DE102018217130A1 (en) | 2018-10-08 | 2018-10-08 | Sunscreen with a combination of waxes and cetyl palmitate |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3863597A1 (en) |
| DE (1) | DE102018217130A1 (en) |
| WO (1) | WO2020074272A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021213749A1 (en) * | 2020-04-21 | 2021-10-28 | Beiersdorf Ag | Color-stable sunscreen |
| DE102020003169A1 (en) | 2020-05-27 | 2021-12-02 | Beiersdorf Aktiengesellschaft | Mineral oil-free W / O emulsion with variable consistency |
| WO2021239478A1 (en) * | 2020-05-28 | 2021-12-02 | Beiersdorf Ag | Sunscreen with a combination of waxes, cetyl palmitate and hydrogenated rapeseed oil |
| DE102021200621A1 (en) | 2021-01-25 | 2022-07-28 | Beiersdorf Aktiengesellschaft | Temperature-stable, mineral oil-free W/O emulsion |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH31287A (en) * | 1991-05-07 | 1998-07-06 | Rihardson Vicks Inc | Photoprotection compositions. |
| DE102017201947A1 (en) * | 2017-02-08 | 2018-08-09 | Beiersdorf Ag | Cosmetic sunscreen pen |
-
2018
- 2018-10-08 DE DE102018217130.0A patent/DE102018217130A1/en not_active Withdrawn
-
2019
- 2019-09-27 EP EP19783241.3A patent/EP3863597A1/en active Pending
- 2019-09-27 WO PCT/EP2019/076212 patent/WO2020074272A1/en unknown
Non-Patent Citations (3)
| Title |
|---|
| Annemarie Börlind Natural Beauty Energy Nature System Pre-Aging. Vitalizing Day Cream. Juni 2016. Mintel GNPD [online]. Eintragsnummer 4029983 [abgerufen am 22.01.2020]. * |
| bareMinerals Jack of All Trades. Lip Balm. August 2013. Mintel GNPD [online]. Eintragsnummer 2158062 [abgerufen am 22.01.2020]. * |
| Deborah Bioetyc Sun Care. Sun Cream SPF 50. Mai 2017. Mintel GNPD [online]. Eintragsnummer 4789291 [abgerufen am 22.01.2020]. * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021213749A1 (en) * | 2020-04-21 | 2021-10-28 | Beiersdorf Ag | Color-stable sunscreen |
| DE102020003169A1 (en) | 2020-05-27 | 2021-12-02 | Beiersdorf Aktiengesellschaft | Mineral oil-free W / O emulsion with variable consistency |
| WO2021239384A1 (en) * | 2020-05-27 | 2021-12-02 | Beiersdorf Ag | Mineral-oil-free w/o emulsion with a variable consistency |
| WO2021239478A1 (en) * | 2020-05-28 | 2021-12-02 | Beiersdorf Ag | Sunscreen with a combination of waxes, cetyl palmitate and hydrogenated rapeseed oil |
| DE102021200621A1 (en) | 2021-01-25 | 2022-07-28 | Beiersdorf Aktiengesellschaft | Temperature-stable, mineral oil-free W/O emulsion |
| WO2022157055A1 (en) | 2021-01-25 | 2022-07-28 | Beiersdorf Ag | Thermally stable, mineral oil-free w/o emulsion |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3863597A1 (en) | 2021-08-18 |
| WO2020074272A1 (en) | 2020-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3173129B1 (en) | Sunscreen comprising titanium dioxide and ethylhexyl salicylate | |
| WO2020074272A1 (en) | Sunscreen with a combination of waxes and cetyl palmitate | |
| EP3195853B1 (en) | Octocrylene-free solar protection formulation with diethylamino hydroxybenzoyl hexyl benzoate. | |
| EP3173130B1 (en) | Sunscreen comprising titanium dioxide and octocrylene | |
| EP2781211A1 (en) | Stable cosmetic preparation | |
| EP3093009A1 (en) | Octocrylene-free sunscreen agent with diethylaminohydroxybenzoylhexylbenzoate | |
| EP3366352B1 (en) | Waterproof, sprayable sun protection agent | |
| WO2021239478A1 (en) | Sunscreen with a combination of waxes, cetyl palmitate and hydrogenated rapeseed oil | |
| EP2485806B1 (en) | Use of cetearyl sulfosuccinates in sunscreen preparations | |
| EP4061313A1 (en) | Novel sunscreen composition containing silica for protection against blue light | |
| EP4103148A1 (en) | Polyacrylate-free cosmetic preparation | |
| EP3746183B1 (en) | O/w emulsion comprising photochemically stable 4-(tert.-butyl)-4'-methoxydibenzoylmethane in oil droplets smaller than 8 micrometers | |
| WO2021063609A1 (en) | Bismuth oxychloride-containing sunscreen for protection from blue light | |
| DE102020204937A1 (en) | Environmentally friendly sunscreen | |
| WO2021239385A1 (en) | Sunscreen with a combination of carnauba wax and hydrogenated rapeseed oil | |
| DE102017202192A1 (en) | Polymer concentrate for sunscreen | |
| WO2021099089A1 (en) | Sunscreen composition containing silica for protection from blue light | |
| WO2021063610A1 (en) | Novel sun protective agent containing bismuth oxychloride for protection against blue light | |
| WO2021110341A1 (en) | Water-resistant cosmetic sunscreen | |
| WO2012168049A2 (en) | USE OF ε-POLYLYSINE (EPSILON-POLYLYSINE) FOR IMPROVING THE WATERPROOFNESS OF COSMETIC OR DERMATOLOGICAL FORMULATIONS | |
| DE102018218740A1 (en) | Cosmetic O / W emulsion with zinc oxide | |
| DE202015009972U1 (en) | Sunscreen containing titanium dioxide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R163 | Identified publications notified | ||
| R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |