DE102011007060A1 - Waterproof, fast drying and water vapor permeable fabric patches - Google Patents

Abstract

A self-adhesive skin pad with a layer structure of hydrophobic and / or oleophobic fabric, a liquid-tight and gas-permeable layer and a water-vapor-permeable adhesive, with the liquid-tight layer facing the skin, offers the user an advantageous tissue feel with simultaneously moisture-regulating properties.

Description

The invention discloses self-adhesive skin coverings with a special layer structure of hydrophobic and / or oleophobic fabric, a liquid-tight and gas-permeable layer and a water-vapor-permeable adhesive.

The skin layer offers the user an advantageous tissue feel with moisture-regulating properties.

For wound dressings, patches, skin coverings and tapes, for example for the fixation of wound dressings and for stabilizing z. As joints, a number of materials are known.

The different materials, from fabric to films to laminates, serve different purposes and applications

So classic fabric patches are not waterproof, so do not protect the wound from water. In addition, they become wet when washing hands, whereby the adhesion is reduced, the wearing comfort is deteriorated and the appearance is deteriorated.

Waterproof fabric patches are therefore unknown.

If water resistance is required, it is necessary to use foil tape. However, these films have the disadvantage that they have no pleasant to the consumer feel.

Textile dressings based on e.g. Cotton, viscose, PE or PP, can create a moist wound healing environment in combination with occlusive support materials. However, there is a risk of maceration of the skin if too much moisture is accumulated under the occlusive carrier material. By maceration is meant a liquid-based softening of the sore-skin, which may result in a softened skin barrier or loss of adhesion. A softened skin barrier can lead to wound healing complications, such as. As infections lead.

EP 826083 A2 describes fabrics that are rendered liquid-tight and gas-permeable by treating them with a curable thixotropic polymer composition with then-containing biologically active molecules. The fabrics can be used in protective clothing and wound care products.

It is known in the art to coat fibers of a fabric with hydrophilic polymer (eg, acrylic resin) or to treat the fabric with fluorochemicals or silicones to render it water repellent and gas permeable.

US 4454191 discloses a waterproof and moisture wicking fabric. It describes a coating with polyorganosiloxanes to make the fabrics waterproof but permeable to water vapor. The feeling when touching the fabric does not change.

In the EP 1260565 A1 describes fabrics that can be made waterproof and breathable by lamination with a polyurethane film.

In DE 3835016 A2 . JP 02249645 . JP 63230337 . JP 59158252 . WO 2009044875 A wide variety of textiles are disclosed, which are waterproof with a variety of coatings and air permeable at the same time. The main application of these textiles is the clothing industry.

Wound dressings are known as BandAid ^® Tough Strips Waterproof or Nexcare ^® Heavy Duty Clear & Tough from the trade, represent the foil patch with integrated fabric structure.

Existing really waterproof patches always have film feel and therefore can not be perceived as fabric patches.

It is desirable to provide wound dressings that are liquid-impermeable, permeable to water vapor, exhibit no maceration, and yet provide tissue feel to the user.

EP 673657 describes an adhesive dressing, wherein on the skin-facing side of a nonwoven fabric is provided with an adhesive layer and on the opposite side a film with water vapor permeability and water impermeability is laminated to the textile composite. The textile composite is composed of elastomeric threads. In this patch construction where the tissue faces the skin, the tissue underlying a watertight film can wick liquid over the open edges by capillary action. Due to these capillary effects, moisture can penetrate from the edge of the support into the wound dressing and lead to the problems described, for example maceration.

In the EP 673657 This problem is described and offered as a solution welding the open edges.

The self-adhesive products based on waterproof textiles (wound dressings, tapes) described in the prior art have in the There are essentially two disadvantages: they lose their textile feel due to the fact that the waterproof layer is applied on the side facing away from the skin, and the textile lying underneath the waterproof layer absorbs liquid at the open edges via capillary forces.

These disadvantages should be improved or avoided.

The invention is a self-adhesive skin layer comprising a layer of hydrophobic and / or oleophobic tissue ( 2 ) to the skin-facing side with a liquid-tight and gas-permeable layer ( 3 ), which in turn leads to the skin-facing side with a water-vapor-permeable adhesive ( 4 ) is coated. The liquid-tight and water vapor-permeable layer ( 3 ) can be z. B. as a dispersion or as a melt directly on the tissue ( 2 ) or laminated in the form of a film on the fabric.

The tissue ( 2 ) is by appropriate equipment ( 1 ) hydrophobic and / or oleophobic (water and oil repellent). The hydrophobization or oleophobization ( 1 ) of the tissue ( 2 ) can be done for example by equipment of fluorocarbon or by using 100% synthetic yarn. Also come as hydrophobic and / or oleophobic equipment ( 1 ) all suitable and suitable for use in wound care products and tapes or bandages chemicals in question, such as paraffins, aluminum and / or zirconium organic acids, fluorocarbons, Aklylsilane, dimethylpolysiloxanes, waxes and / or mixtures thereof in question. The in the EP 826083 A2 described possibilities of hydrophobization or oleophobization are part of the present disclosure.

Skin layers according to the invention are wound dressings, tapes, bandages, patches, plasters, pads and dressings. The requirements may be designed drug-free as well as containing active ingredient.

Self-adhesive means that the skin layer will adhere to the skin for a certain period of time without any additional additional fasteners. Of course, the period and the bond strength can be individually adapted to the required conditions. Thus, a wound plaster is to provide a higher bond strength and adhesion than a cosmetic pad. The self-adhesive is through the adhesive layer ( 4 ) reached.

The adhesive may be selected from various materials such as acrylates, rubber (natural or synthetic), polyurethane, silicone or hydrocolloids.

The water vapor permeable coating with adhesive ( 4 ) can be done in different ways. Preferably, a full-surface coating with a water vapor permeable adhesive, z. B. of polyacrylate, silicone or polyurethane. However, the application of the adhesive may also be carried out only partially (eg screen printing, strip coating) in order to achieve good water vapor permeability. In this case, in addition to the adhesives already mentioned also occlusive adhesives can be used, for. B. based on natural and / or synthetic rubber. For better absorption and passage of water vapor, the adhesives z. B. also be added a hydrocolloid, z. As carboxymethylcellulose, Na salts of polyacrylic acid. Suitable adhesives include hotmelt compositions as well as solvents, including water, based adhesives. Also, the adhesive may contain medical, dermatological or cosmetic agents that are delivered to the skin over time.

The adhesive ( 4 ) is wholly or partially on the liquid-tight layer ( 3 ) applied.

The application as well as the type of adhesive can, in turn, be adapted individually to the required conditions, depending on the requirements.

The adhesive ( 4 ) may be composed of one or more different adhesives. Likewise, the layer ( 3 ) are coated at different points with different adhesives. This allows individual adaptation of the bond of the pad according to the invention to the required conditions, such as adhesion to joints, facial skin, hairy spots, etc.

In contrast to skin dressings and wound dressings of the prior art, the liquid-tight layer (in the edition according to the invention) is 3 ) applied to the skin-facing side of the fabric, for example, laminated. As a liquid-tight and gas-permeable, thus water-vapor-permeable and breathable, layer ( 3 ), a polyurethane film is preferred. As an alternative to the polyurethane film, it is also preferred according to the invention for a layer obtained from a polyurethane or acylate dispersion (US Pat. 3 ) to be available.

Layer ( 3 ) According to the invention advantageously by means of a laminated vapor-permeable film, for. As polyurethane, copolyester or a microporous film, for. Example of PE, PP, polyamide, polyester, polyether ester or PTFE, or a flowable, z. B. from the melt, from a Dispersion or a solution applied polymer layer, for. B. of silicone, polyurethane or polyacrylate, are generated.

Advantageously, the thickness of the film is about 10 to 100 microns. The order of u. U. flexible film can be done by casting or extrusion. Suppliers of known films are established film manufacturers, such as the companies SNEF or Epurex.

According to the invention, a film having a water vapor transmission rate (WVTR) of more than 300 g / m ² in 24 hours is considered to be permeable to water vapor.

Advantageously, the layer ( 3 ) Breathability and water vapor permeability of> 350 g / m ^2/24 hr after listed in Example 1 method.

Due to this layer structure, the fabric layer ( 2 ) to the side facing away from the skin and offers the user the desired tissue haptics, which he perceives externally and noticed.

Due to the hydrophobic or oleophobic formation ( 1 ) of the tissue ( 2 ) a wetting of the upper tissue layer is reduced or prevented.

The foil ( 3 ) directly on the skin and the tissue ( 2 ) to point outward (skin-facing) to place failed so far on the requirement that the fabric is to be kept dry.

In prior art adhesive tape embodiments having combinations of fabric and waterproof layers, the waterproof layer always faces outward. Thus, while the fabric is kept dry, the product loses its fabric feel and is more likely to be perceived as a film product.

Another advantage of the structure according to the invention is that the fabric can dry faster if it is even wetted or wet with liquid. The hydrophobing and / or Oleophobierung prevents the fabric threads themselves can be saturated with liquid. Liquid can thus penetrate only in or through the spaces between the threads of the tissue. The waterproof layer underneath the fabric, however, ensures that the liquid does not penetrate deeper, but remains on the surface, where it can evaporate quickly. A further decisive advantage is that, in contrast to plaster constructions in which the tissue points to the skin, no capillary effects can occur which can draw moisture from the edge of the support into the wound dressing.

As in EP 673657 A2 described that by the underlying non-woven under a waterproof film can absorb liquid via the open edges by capillary action, the structure according to the invention easily bypasses these disadvantages by the tissue facing out and the waterproof layer is arranged underneath, to the adhesive.

The product structure according to the invention thus does not have the serious disadvantages of the loss of textile feel and the sucking out of liquid.

As tissue are any form of textiles, such as fabrics, knitted fabrics, knitted fabrics, nonwovens, etc. to understand. In principle, all suitable self-adhesive wound care products, tapes and bandages textile carrier materials in question. The underlying fibers or yarns are usually made of cotton, viscose, cellulose acetate, polyester, PE, PP, polyamide and mixtures thereof - but other materials are conceivable.

The basis weight of the fabric layer ( 2 ) is advantageously selected in the range of 80 to 200 g / m ² .

Advantageously, the bond between the tissue ( 2 ) and the liquid-tight and water vapor-permeable layer ( 3 ) and the composite of the water vapor-permeable layer ( 3 ) and the adhesive ( 4 ) significantly stronger than the bonding of the patch to the skin.

The adhesive forces in the composite of layers ( 2 ) and ( 3 ) such as ( 3 ) and ( 4 ) are ideally approximately the same.

This difference in adhesion between the various layers of the dressing and the adhesion to the skin prevents destruction and tearing of the skin patch when it is removed from the skin.

Common patches have an adhesive force on the skin in the range of 20 to 200 cN / cm. However, regardless of the specific adhesion of the pads according to the invention on the skin, the adhesion between the layers ( 2 ) and ( 3 ) such as ( 3 ) and ( 4 ) According to the invention preferably larger to choose.

Thus, the cohesiveness is sufficient enough to meet the necessary application properties as a self-adhesive pad when glued to the skin and to be deducted without residue from the application site after application.

The conditions according to the invention, in particular as wound care products, ie as Wound plaster, perceived by the consumer as a textile patch and signal and ensure stability and robustness. On the other hand, prior art film plasters act rather than non-dimensionally stable and "labile".

The stability, in particular dimensional stability of the plaster according to the invention, which is associated with the water resistance of the fabric, ensures a more stable functionality, such as the protection of a wound, than do customary textile or foil patches.

In the plaster according to the invention, both the textile plaster properties and the film-paving properties are combined.

Due to the textile character and a "more natural" perception, the plaster according to the invention is therefore preferred by the user.

shows a schematic structure of the fabric patch according to the invention. The tissue ( 2 ) with hydrophobic and / or oleophobic equipment ( 1 ) is provided on the skin-facing side with a waterproof breathable layer ( 3 ), z. As a laminated PU film or an applied acrylate. On this layer ( 3 ) is again an adhesive layer ( 4 ) applied, which ensures the adhesion of the patch on the skin.

If the support according to the invention is designed as a wound care product, it is possible to apply to the adhesive layer ( 4 ) one or more nonwoven wound dressing ( 5 ) be applied.

The inventive coating may comprise active ingredients and function as a transdermal system.

As active ingredients, the known pharmaceutical and / or cosmetic active ingredients can be selected. The active substance (s) are preferably selected from the group Coenzyme Q10, 3- (menthoxy) propane-1,2-diol, ((1R, 2S, 5R) -N- (2- (2-pyridinyl) ethyl) -2- isopropyl-5-methylcyclohexanecarboxamide), AGR, glycerylglucose, ibuprofen and its salts, etofenamate, indomethacin, diclofenac and its salts, acetylsalicylic acid, licochalcone A, bakuchiol, acyclovir, decanediol, camitine, n-4-butyl-resorcinol, magnolol, honokiol, Paeonol and salicylic acid.

The active compounds are advantageous in a proportion of 0.001-10 wt.%, Preferably 0.01-5 wt.%, Particularly preferably 0.05-1 wt.%, Preferably 0.01-0.5 wt.%, Based on the total mass of the layer they contain contained in the edition.

The active ingredients can be used on the one hand in the adhesive ( 4 ) and / or in the liquid-tight layer ( 3 ). In the case of, for example, grid-shaped adhesive application, it is thus possible to produce active substances from the film ( 3 ) and at the same time other active substances from the adhesive ( 4 ) get into or on the skin.

The following examples illustrate the skin conditions according to the invention.

example 1

It is a support made of cross-elastic fabric with a basis weight 100 g / m ² , warp threads of viscose (thread count 35 / cm) and weft threads made of polyamide (thread count 14 / cm). The hydrophobic / oleophobic equipment is made with 1-2% ramasite KGT (paraffin-wax emulsion with aluminum salt) and 0.5-1% fluorocarbon (eg Rucostar EEE6 from Rodulf Chemie).

The liquid-tight layer was obtained by applying directly to the fabric a polyacrylate layer (eg Ruco-Coat AC 3330 and Ruco-Coat AC 7510 from Rudolf Chemie) with a basis weight of 80-100 g / m ² . This laminate was then coated with a UV-crosslinkable acrylate adhesive (Sanicare UV 4450-21, Henkel) with a coat application of 65 g / m ² and a UV dose of 75 mJ / cm ² .

Subsequently, plasters were punched out and a fleece wound pad made of polypropylene was placed in the middle in the form of an Iceland dressing.

The water vapor permeability was about 400 g / m ^2/24 determines h.

• • Die Öffnung des Prüfgefäßes beträgt 804 mm²
• • Das Material wird 24 Std. vorkonditioniert bei 23 ± 2°C und 50 ± 5% rel. Luftfeuchte (LF)
• • Der Abstand zwischen Wasserspiegel im Prüfgefäß und der Probe beträgt 35 ± 5 mm
• • Das Rückwiegen der mit Proben bestückten Prüfgefäße erfolgt nach 24 Std., in denen diese im Klimaschrank bei 37 ± 1,5°C und 30 ± 3% rel. LF gelagert wurden

The water vapor permeability is according to ASTM E 96 (water method), with the following data:

• • The opening of the test vessel is 804 mm ²
• • The material is preconditioned for 24 hours at 23 ± 2 ° C and 50 ± 5% rel. Humidity (LF)
• • The distance between the water level in the test vessel and the sample is 35 ± 5 mm
• • Weigh out the test vessels equipped with samples after 24 hours, during which they are stored in a climate chamber at 37 ± 1.5 ° C and 30 ± 3% rel. LF were stored

The product was liquid tight according to the test method described below for determining liquid tightness.

Method for determining the liquid-tightness:

500 ml of tap water are placed in a beaker. There are 2 g of liquid hand soap (eg Nivea Creme Soft) and 1 ml sodium hydroxide solution (45%). The patch to be tested is adhered to a glass plate (5 cm x 20 cm), wherein under the wound dressing a piece of pH indicator paper is laid, which turns to blue in the alkaline range.

Together with the glass plate, the plaster stuck in this way is dipped into the solution prepared in the beaker.

If no color change occurs within a 20-minute period, the product tested is liquid-tight.

Example 2

• Fabric: 100% polyester
• Hydrophobic Equipment: 1-2% Hydrophobol APK (paraffin with aluminum salt)

The liquid-tight layer was obtained by applying directly to the fabric a polyacrylate layer (eg Ruco-Coat AC 3330 and Ruco-Coat AC 7510) having a basis weight of 80-100 g / m ² . This laminate was coated with a UV-crosslinkable acrylate adhesive (M14.1070, nolax), coat application 75 g / m ² and UV dose 40 mJ / cm ² .

Subsequently, plasters were punched out and a fleece wound pad made of polypropylene was placed in the middle in the form of an Iceland dressing.

The water vapor permeability was about 400 g / m ^2/24 determines h.

The product was also liquid tight in the test listed in Example 1.

Example 3

• Fabric: 100% cotton, basis weight 170 g / m ² , warp: 170/10 cm, 60x1 tex,
• Weft threads: 145/10 cm, 34x1 tex

Hydrophobic / oleophobic finish: 1-2% hydrophobol APK + 0.5-1% fluorocarbon (eg Rucostar EEE6 from Rudolf Chemie)

A 20 μm thin polyurethane film was laminated to the fabric using a PU pressure-sensitive hotmelt adhesive. This laminate was coated with a UV-crosslinkable acrylate adhesive (M14.1070, nolax), coat application 65 g / m ² and UV dose 40 mJ / cm ² .

Subsequently, plasters were punched out and a fleece wound pad made of polypropylene was placed in the middle in the form of an Iceland dressing.

The water vapor permeability was measured to be about 600 g / m ^2/24 determines h.

The product was liquid-tight in the test listed in Example 1.

Example 4

It is a pad made of cross-elastic fabric with a basis weight of about 160 g / m ² , warp threads made of cotton and weft threads made of polyamide. The hydrophobic / oleophobic equipment is made with 1-2% Hydrophobol APK (paraffin with aluminum set) and 0.5-1% fluorocarbon (eg Rucostar EEE6 from Rodulf Chemie).

The liquid-tight layer was obtained by applying directly to the fabric a polyacrylate layer (eg Ruco-Coat AC 3330 and Ruco-Coat AC 7510) having a basis weight of 80-100 g / m ² .

This laminate was coated with a UV-curable acrylate adhesive (M14.1070, nolax), coat application 75 g / m ² and UV dose 50 mJ / cm ² .

Subsequently, plasters were punched out and a fleece wound pad made of polypropylene was placed in the middle in the form of an Iceland dressing.

The water vapor permeability was measured to about 450 g / m ^2/24 determines h.

The product was liquid-tight in the test listed in Example 1.

QUOTES INCLUDE IN THE DESCRIPTION

This list of the documents listed by the applicant has been generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.

Cited patent literature

• EP 826083 A2 [0009, 0022]
• US 4454191 [0011]
• EP 1260565 A1 [0012]
• DE 3835016 A2 [0013]
• JP 02249645 [0013]
• JP 63230337 [0013]
• JP 59158252 [0013]
• WO 2009044875 [0013]
• EP 673657 [0017, 0018]
• EP 673657 A2 [0040]

Cited non-patent literature

• ASTM E 96 [0064]

Claims (4)

Self-adhesive skin layer comprising a layer of tissue ( 2 ) with hydrophobic and / or oleophobic equipment ( 1 ) to the skin-facing side with a liquid-tight and gas-permeable layer ( 3 ), which in turn leads to the skin-facing side with a gas-permeable adhesive ( 4 ) is coated. An overlay according to claim 1, characterized in that the liquid-tight layer ( 3 ) consists of polyurethane and / or acrylates. Pad according to one of the preceding claims, characterized in that in the liquid-tight layer ( 3 ) and / or the adhesive ( 4 ) One or more active ingredients are included. An overlay according to any one of the preceding claims as a wound care product, by applying to the adhesive ( 4 ) one or more textile wound dressings ( 5 ) are arranged.

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