DE102008033105A1 - Mouth and dental care cleaning agents, useful as mouth and tooth-powders, -pastes, -creams and -gels, comprise flowable carrier containing water, and flowable carrier suspended particle containing cellulose - Google Patents

Abstract

Mouth- and dental -care cleaning agents comprise flowable carrier containing at least 5 wt.% of water; and flowable carrier suspended particle containing at least 70 wt.% of cellulose.

Description

The Invention relates to oral and dental care and cleaning agents, which have a special look.

Dentifrice are in different forms in the market and serve first Line of cleaning the tooth surface and prevention of dental and gum diseases. They usually contain a combination of polishes, humectants, surfactants, Binders, flavorings and fluoride-containing and antimicrobial Agents. In addition to toothpowder, because of their increased Abrasiveness play a minor role, become dentifrices especially in paste, cream and translucent or more transparent Gel form offered. In recent years, also have liquid or Liquid toothpastes and mouthwash increasingly on Gained importance.

Next the cleaning of the teeth expects the consumer of the generic products also a care of Teeth and the oral cavity. So are in particular a "clean" feeling, that is, a smooth and shiny one Tooth surface and a fresh feeling in the mouth essential aspects for the buying incentive of preparations for oral and dental care and cleaning. A successful remedy The generic type should therefore be the teeth Thoroughly clean, without the tooth or the tooth surface to harm and at the same time reduce bad breath and / or prevent.

It is known, preparations for oral and dental care and cleaning Adding odors and / or flavors or flavors to them on the one hand to give a special smell or taste and on the other hand, for an aromatic feeling of freshness to leave the application. Such flavors etc. are in the range oral and dental care and cleaning widely used.

It has shown that the commonly used Flavors the consumer interest for a unique product sensation only inadequate or only over a certain period of time to satisfy. There is therefore still the need, the consumer a "typical and distinctive" product available He repeatedly buys and applies it.

to To avoid hygienic concerns, oral preparations are and dental care and cleaning so packaged that a direct Contact with the product at the point of sale is not possible. Unlike other cosmetics, such as showering or Shampoos, have the packaging securing means (eg peel-of-films) on, which prevent the product from contacting the point of sale with the environment receives. The consumer can also through Unscrewing the closure thus not perceiving the product olfactorily, as is the case with a shower gel, for example. this leads to that further efforts are needed, the product already at the point of sale as "typical and unmistakable" Product. Here are next to the packaging design also optical differentiations of the product.

One Another task is to provide the consumer with as close to nature as possible. To provide products that are only the absolute necessary quantities of synthetic substances.

Of the Present invention was based on the object, forms of preparation for oral and dental care and cleaners already create a unique sensation at the point of sale. additionally should, if possible, the additional use reduced or completely dispensed with by synthetic substances can.

It is known, oral and dental care and cleaning optically to differentiate. Here are the different ones To mention types of strip-tooth pastes that are over Type, color and shape as well as location of the stripes a message n the Communicate consumers. Another form of optical differentiation is colored particles, flakes of films or gas bubbles in to incorporate the oral and dental care and cleansers.

That's how it describes WO 2005/058265 A1 (Colgate-Palmolive) the incorporation of drug-loaded films, ie a variety of platelet-shaped structures containing active ingredients in various cosmetics, especially in dentifrices. Film materials are called synthetic polymers. However, the oral and dental care and cleaning agents that act as a carrier are limited in their water content, since the said polymers are water-soluble or swellable.

Of the The present invention was based on the object, an optical differentiation regardless of the water content of the oral and dental care and to allow cleaning agents.

Surprisingly it has now been found that optical differentiation of water-containing mouth and dental care and cleaning products succeeds by incorporating visible cellulose particles into them.

• a) der fließfähige Träger – bezogen auf sein Gewicht – mindestens 5 Gew.-% Wasser enthält, und
• b) die im fließfähigen Träger suspendierten Partikel – bezogen auf ihr Gewicht – mindestens 70 Gew.-% Cellulose enthalten.

Accordingly, the subject matter of the present invention is oral and dental care and cleaning compositions containing a flowable carrier and particles suspended therein in which

• a) the flowable carrier - based on its weight - contains at least 5 wt .-% water, and
• b) the suspended in the flowable carrier particles - based on their weight - at least 70 wt .-% cellulose.

Mouth- and dentifrices as well as mouth and tooth cleaning agents in the sense The invention includes oral and dental powders, oral and toothpastes, liquid Mouth and tooth creams and oral and dental gels. Preferably suitable are toothpastes and liquid dentifrices. For this can the oral and dental care and cleaning agents z. B. in the form of toothpastes, liquid toothpastes, toothpowder, Oral or, if appropriate, as a gum, z. B. as chewing gum. Preferably, however, they are more or less flowable or plastic toothpastes before, how to clean the teeth using a toothbrush be used.

Under "flowable" For the purposes of the present invention, compositions are understood as meaning at 20 ° C and 1013.25 mbar viscosities between 0.001 and 1,000,000 mPas (= 1 μPas to 1 kPas). Preferred preparations according to the invention have Viscosities between 0.1 and 500,000 mPas, preferably between 1 and 250,000 mPas and in particular between 100 and 75,000 mPas on.

In a further preferred embodiment of the invention the agents have a viscosity [mPas] in the range of 8,000 to 45,000 mPas (measured with Brookfield RVF; 4/4 rpm at 20 ° C).

The Compositions according to the invention are aqueous Agents whose aqueous carrier is at least 5 Wt .-% water. Its amount can indeed after further Ingredients vary, particularly preferred inventive Oral and dental care and cleaning products are characterized that the flowable carrier - related on its weight - at least 10 wt .-%, preferably at least 20 wt .-%, particularly preferably at least 30 wt .-%, more preferably at least 40% by weight and in particular at least 50% by weight of water contains.

When Water can be used ordinary tap water, depending on Origin contains different amounts of hardness formers. If tap water in the inventive Contains compositions, this preferably has degrees of hardness between 0 and 20 ° dH. Particularly preferred is the use technically demineralized water, for example by ion exchange can be won. Other ingredients of the flowable Carriers are described in detail below.

When second essential ingredient contain the inventive Oral and dental care and cleaning particles that are flowable Suspended carrier and thus visually present.

These suspended in the flowable carrier Particles contain - based on their weight - at least 70 Wt .-% cellulose.

Cellulose is the isotactic β-1,4-polyacetate of cellobiose (C ₆ H ₁₀ O ₅ ) _n and forms unbranched, water-insoluble chains. The average molecular weights are 50,000-500,000 gmol ^-1 .

Of the average degree of polymerization (DP) as well as the number of Carboxy groups of cellulose can be different by different physical Measurements are determined. The most common are viscosity measurements used to determine the DP, depending on its biological origin give characteristic values.

Under The term "cellulose" fall within the scope of the present Registration also chemically processed celluloses, not, however derivatized celluloses such as cellulose esters and ether.

As cellulose in the context of the present invention, for example, microcrystalline cellulose (Hydrocellulose) can be used. Microcrystalline cellulose is the name given to products obtained by partial hydrolysis of celluloses under conditions in which only the amorphous regions of these semi-crystalline polysaccharides are attacked and completely dissolved. This gentle hydrolysis also proceeds in the alkaline, but is preferably carried out in an acidic medium, for. B. by the action of dilute aqueous hydrochloric acid or sulfuric acid. In yields which correspond almost to the crystalline proportions (-70%) of the celluloses, initially result in micro-fine celluloses, which are disaggregated in aqueous suspension under mechanical force in microcrystalline cellulose. The degree of polymerization (LODP) of the microcrystalline cellulose correlates closely with the crystallite size of the starting celluloses and is in the range of about 30-400. Microcrystalline cellulose forms stable gels with water even at low concentrations (eg, 0.5% by weight). Formed from concentrated suspensions shaped bodies of ivory-like appearance are characterized by high hardness and low flammability. Microcrystalline celluloses are marketed as white powders.

When Cellulose are in the context of the present invention, for example Also viscose, modal, copper silk, rayon used. Also in the class of cellulosic fibers or particles are the Tencel and lyocell fibers or particles. These are with the same basic process produced. This is native cellulose first chemically modified and then by means of spinning or Molded nozzles placed in a bath containing fibers or Formed from cellulose. Usually the degree of polymerization of these celluloses is less than that the native starting cellulose.

The suspended in the flowable carrier Particles contain - based on their weight - at least 70 Wt .-% cellulose. Embodiments are preferred which the particles - based on their weight - at least 75% by weight, preferably at least 80% by weight, more preferably at least 85 wt .-% and in particular at least 90 wt .-% cellulose.

Preferably are the particles that mainly contain cellulose, loaded with active ingredients and / or auxiliaries. Here, for example, offer Dyes, fragrances, oils, flavors, anti-caries active ingredients, active against Halitosis, etc. Particularly preferred invention Oral and dental care and cleaning products are characterized that in the flowable carrier suspended particles - by weight - 0,01 contain up to 20% by weight of perfume (s) and / or flavorings.

When water-insoluble aroma oils are all for Oral and dental care products in use natural and synthetic flavors. Natural flavors can both in the form of the essential oils isolated from the drugs as well as in the form of isolated from these individual components become. Preferably, at least one aroma oil from the Group Peppermint oil, spearmint oil, aniseed oil, Star anise, caraway oil, eucalyptus oil, Fennel oil, cinnamon oil, clove oil, geranium oil, Sage oil, Pimento oil, Thyme oil, Marjoram oil, Basil oil, citrus oil, Gaultheria oil or one or more components of these oils isolated or synthetically produced therefrom be included. The main components of the oils mentioned are z. Menthol, carvone, anethole, cineole, eugenol, cinnamaldehyde, Caryophyllene, geraniol, citronellol, linalool, salvos, thymol, terpinene, terpinol, Methylchavicol and methyl salicylate. Other suitable flavors are z. Menthyl acetate, vanillin, ionone, linalyl acetate, rhodinol and Piperitone.

Especially preferred oral and dental hygiene and cleaning agents are characterized in that the suspended in the flowable carrier Particles - based on their weight - 0.05 to 19 wt .-%, preferably 0.1 to 18 wt .-%, particularly preferably 0.5 to 17 wt .-%, more preferably 0.75 to 16 wt .-% and in particular 1 to 15% by weight of at least one flavor from the group of peppermint, Spearmint, Menthol, Lime, Lime, Apple, Orange, Lemon, Strawberry, Aloe vera, containing chewing gum.

• – 2E,4E-Decadiensäure-N-Methylamid
• – 2E,4E-Decadiensäure-N-Ethylamid
• – 2E,4E-Decadiensäure-N-n-Propylamid
• – 2E,4E-Decadiensäure-N-Isopropylamid
• – 2E,4E-Decadiensäure-N-n-Butylamid
• – 2E,4E-Decadiensäure-N-(1-Methylpropyl)-amid
• – 2E,4E-Decadiensäure-N-Isobutylamid
• – 2E,4E-Decadiensäure-N-tert-Butylamid
• – 2E,4Z-Decadiensäure-N-Methylamid
• – 2E,4Z-Decadiensäure-N-Ethylamid
• – 2E,4Z-Decadiensäure-N-n-Propylamid
• – 2E,4Z-Decadiensäure-N-Isopropylamid
• – 2E,4Z-Decadiensäure-N-n-Butylamid
• – 2E,4Z-Decadiensäure-N-(1-Methylpropyl)-amid
• – 2E,4Z-Decadiensäure-N-Isobutylamid
• – 2E,4Z-Decadiensäure-N-tert-Butylamid
• – 2E,4E,8Z-Decatriensäure-N-Methylamid
• – 2E,4E,8Z-Decatriensäure-N-Ethylamid
• – 2E,4E,8Z-Decatriensäure-N-n-Propylamid
• – 2E,4E,8Z-Decatriensäure-N-Isopropylamid
• – 2E,4E,8Z-Decatriensäure-N-n-Butylamid
• – 2E,4E,8Z-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,4E,8Z-Decatriensäure-N-Isobutylamid
• – 2E,4E,8Z-Decatriensäure-N-tert-Butylamid
• – 2E,4Z,8Z-Decatriensäure-N-Methylamid
• – 2E,4Z,8Z-Decatriensäure-N-Ethylamid
• – 2E,4Z,8Z-Decatriensäure-N-n-Propylamid
• – 2E,4Z,8Z-Decatriensäure-N-Isopropylamid
• – 2E,4Z,8Z-Decatriensäure-N-n-Butylamid
• – 2E,4Z,8Z-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,4Z,8Z-Decatriensäure-N-Isobutylamid
• – 2E,4Z,8Z-Decatriensäure-N-tert-Butylamid
• – 2E,4E,8E-Decatriensäure-N-Methylamid
• – 2E,4E,8E-Decatriensäure-N-Ethylamid
• – 2E,4E,8E-Decatriensäure-N-n-Propylamid
• – 2E,4E,8E-Decatriensäure-N-Isopropylamid
• – 2E,4E,8E-Decatriensäure-N-n-Butylamid
• – 2E,4E,8E-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,4E,8E-Decatriensäure-N-Isobutylamid
• – 2E,4E,8E-Decatriensäure-N-tert-Butylamid
• – 2E,4Z,8E-Decatriensäure-N-Methylamid
• – 2E,4Z,8E-Decatriensäure-N-Ethylamid
• – 2E,4Z,8E-Decatriensäure-N-n-Propylamid
• – 2E,4Z,8E-Decatriensäure-N-Isopropylamid
• – 2E,4Z,8E-Decatriensäure-N-n-Butylamid
• – 2E,4Z,8E-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,4Z,8E-Decatriensäure-N-Isobutylamid
• – 2E,4Z,8E-Decatriensäure-N-tert-Butylamid
• – 2E,6Z,8E-Decatriensäure-N-Methylamid
• – 2E,6Z,8E-Decatriensäure-N-Ethylamid
• – 2E,6Z,8E-Decatriensäure-N-n-Propylamid
• – 2E,6Z,8E-Decatriensäure-N-Isopropylamid
• – 2E,6Z,8E-Decatriensäure-N-n-Butylamid
• – 2E,6Z,8E-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,6Z,8E-Decatriensäure-N-Isobutylamid
• – 2E,6Z,8E-Decatriensäure-N-tert-Butylamid
• – 2E,6E,8E-Decatriensäure-N-Methylamid
• – 2E,6E,8E-Decatriensäure-N-Ethylamid
• – 2E,6E,8E-Decatriensäure-N-n-Propylamid
• – 2E,6E,8E-Decatriensäure-N-Isopropylamid
• – 2E,6E,8E-Decatriensäure-N-n-Butylamid
• – 2E,6E,8E-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,6E,8E-Decatriensäure-N-Isobutylamid
• – 2E,6E,8E-Decatriensäure-N-tert-Butylamid
• – 2E,6Z,8Z-Decatriensäure-N-Methylamid
• – 2E,6Z,8Z-Decatriensäure-N-Ethylamid
• – 2E,6Z,8Z-Decatriensäure-N-n-Propylamid
• – 2E,6Z,8Z-Decatriensäure-N-Isopropylamid
• – 2E,6Z,8Z-Decatriensäure-N-n-Butylamid
• – 2E,6Z,8Z-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,6Z,8Z-Decatriensäure-N-Isobutylamid
• – 2E,6Z,8Z-Decatriensäure-N-tert-Butylamid
• – 2E,6E,8Z-Decatriensäure-N-Methylamid
• – 2E,6E,8Z-Decatriensäure-N-Ethylamid
• – 2E,6E,8Z-Decatriensäure-N-n-Propylamid
• – 2E,6E,8Z-Decatriensäure-N-Isopropylamid
• – 2E,6E,8Z-Decatriensäure-N-n-Butylamid
• – 2E,6E,8Z-Decatriensäure-N-(1-Methylpropyl)-amid
• – 2E,6E,8Z-Decatriensäure-N-Isobutylamid
• – 2E,6E,8Z-Decatriensäure-N-tert-Butylamid
• – 2E,7Z,9E-Undecatriensäure-N-Methylamid
• – 2E,7Z,9E-Undecatriensäure-N-Ethylamid
• – 2E,7Z,9E-Undecatriensäure-N-n-Propylamid
• – 2E,7Z,9E-Undecatriensäure-N-Isopropylamid
• – 2E,7Z,9E-Undecatriensäure-N-n-Butylamid
• – 2E,7Z,9E-Undecatriensäure-N-(1-Methylpropyl)-amid
• – 2E,7Z,9E-Undecatriensäure-N-isobutylamid
• – 2E,7Z,9E-Undecatriensäure-N-tert-Butylamid
• – 2E,7E,9E-Undecatriensäure-N-Methylamid
• – 2E,7E,9E-Undecatriensäure-N-Ethylamid
• – 2E,7E,9E-Undecatriensäure-N-n-Propylamid
• – 2E,7E,9E-Undecatriensäure-N-Isopropylamid
• – 2E,7E,9E-Undecatriensäure-N-n-Butylamid
• – 2E,7E,9E-Undecatriensäure-N-(1-Methylpropyl)-amid
• – 2E,7E,9E-Undecatriensäure-N-isobutylamid
• – 2E,7E,9E-Undecatriensäure-N-tert-Butylamid
• – 2E,7Z,9Z-Undecatriensäure-N-Methylamid
• – 2E,7Z,9Z-Undecatriensäure-N-Ethylamid
• – 2E,7Z,9Z-Undecatriensäure-N-n-Propylamid
• – 2E,7Z,9Z-Undecatriensäure-N-Isopropylamid
• – 2E,7Z,9Z-Undecatriensäure-N-n-Butylamid
• – 2E,7Z,9Z-Undecatriensäure-N-(1-Methylpropyl)-amid
• – 2E,7Z,9Z-Undecatriensäure-N-isobutylamid
• – 2E,7Z,9Z-Undecatriensäure-N-tert-Butylamid
• – 2E,7Z,9E-Undecatriensäure-N-Methylamid
• – 2E,7Z,9E-Undecatriensäure-N-Ethylamid
• – 2E,7Z,9E-Undecatriensäure-N-n-Propylamid
• – 2E,7Z,9E-Undecatriensäure-N-Isopropylamid
• – 2E,7Z,9E-Undecatriensäure-N-n-Butylamid
• – 2E,7Z,9E-Undecatriensäure-N-(1-Methylpropyl)-amid
• – 2E,7Z,9E-Undecatriensäure-N-isobutylamid
• – 2E,7Z,9E-Undecatriensäure-N-tert-Butylamid

The particles suspended in the flowable carrier may, in addition to flavorings and / or dyes or in their place, also contain pungent or heat-generating substances. As a pungent or a feeling of heat generating substance, a number of substances can be used. Preference is given in particular to N-alkyl-substituted amides of unsaturated carboxylic acids, for example

• 2E, 4E-decadienoic acid N-methylamide
• 2E, 4E-decadienoic acid N-ethylamide
• 2E, 4E-decadienoic acid-Nn-propylamide
• 2E, 4E-decadienoic acid N-isopropylamide
• 2E, 4E-decadienoic acid-Nn-butylamide
• 2E, 4E-decadienoic acid N- (1-methylpropyl) -amide
• 2E, 4E-decadienoic acid N-isobutylamide
• 2E, 4E-decadienoic acid N-tert-butylamide
• 2E, 4Z-decadienoic acid N-methylamide
• 2E, 4Z-decadienoic acid N-ethylamide
• 2E, 4Z-decadienoic acid-Nn-propylamide
• 2E, 4Z-decadienoic acid N-isopropylamide
• 2E, 4Z-decadienoic acid-Nn-butylamide
• 2E, 4Z-decadienoic acid N- (1-methylpropyl) -amide
• 2E, 4Z-decadienoic acid N-isobutylamide
• 2E, 4Z-decadienoic acid N-tert-butylamide
• 2E, 4E, 8Z-decatrienoic acid N-methylamide
• 2E, 4E, 8Z-decatrienoic acid N-ethylamide
• 2E, 4E, 8Z-decatrienoic acid-Nn-propylamide
• 2E, 4E, 8Z-decatrienoic acid N-isopropylamide
• 2E, 4E, 8Z-decatrienoic acid-Nn-butylamide
• 2E, 4E, 8Z-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 4E, 8Z-decatrienoic acid N-isobutylamide
• 2E, 4E, 8Z-decatrienoic acid N-tert-butylamide
• 2E, 4Z, 8Z-decatrienoic acid N-methylamide
• 2E, 4Z, 8Z-decatrienoic acid N-ethylamide
• 2E, 4Z, 8Z-decatrienoic acid-Nn-propylamide
• 2E, 4Z, 8Z-decatrienoic acid N-isopropylamide
• 2E, 4Z, 8Z-decatrienoic acid-Nn-butylamide
• 2E, 4Z, 8Z-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 4Z, 8Z-decatrienoic acid N-isobutylamide
• 2E, 4Z, 8Z-decatrienoic acid N-tert-butylamide
• 2E, 4E, 8E-Decatrienoic acid N-methylamide
• 2E, 4E, 8E-decatrienoic acid N-ethylamide
• 2E, 4E, 8E-decatrienoic acid-Nn-propylamide
• 2E, 4E, 8E-decatrienoic acid N-isopropylamide
• 2E, 4E, 8E-decatrienoic acid-Nn-butylamide
• 2E, 4E, 8E-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 4E, 8E-decatrienoic acid N-isobutylamide
• 2E, 4E, 8E-Decatrienoic acid N-tert-butylamide
• 2E, 4Z, 8E-decatrienoic acid N-methylamide
• 2E, 4Z, 8E-decatrienoic acid N-ethylamide
• 2E, 4Z, 8E-decatrienoic acid-Nn-propylamide
• 2E, 4Z, 8E-decatrienoic acid N-isopropylamide
• 2E, 4Z, 8E-decatrienoic acid-Nn-butylamide
• 2E, 4Z, 8E-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 4Z, 8E-decatrienoic acid N-isobutylamide
• 2E, 4Z, 8E-decatrienoic acid N-tert-butylamide
• 2E, 6Z, 8E-decatrienoic acid N-methylamide
• 2E, 6Z, 8E-decatrienoic acid N-ethylamide
• 2E, 6Z, 8E-decatrienoic acid-Nn-propylamide
• 2E, 6Z, 8E-decatrienoic acid N-isopropylamide
• 2E, 6Z, 8E-decatrienoic acid-Nn-butylamide
• 2E, 6Z, 8E-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 6Z, 8E-decatrienoic acid N-isobutylamide
• 2E, 6Z, 8E-decatrienoic acid N-tert-butylamide
• 2E, 6E, 8E-Decatrienoic acid N-methylamide
• 2E, 6E, 8E-decatrienoic acid N-ethylamide
• 2E, 6E, 8E-decatrienoic acid-Nn-propylamide
• 2E, 6E, 8E-decatrienoic acid N-isopropylamide
• 2E, 6E, 8E-decatrienoic acid-Nn-butylamide
• 2E, 6E, 8E-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 6E, 8E-decatrienoic acid N-isobutylamide
• 2E, 6E, 8E-Decatrienoic acid N-tert-butylamide
• 2E, 6Z, 8Z-decatrienoic acid N-methylamide
• 2E, 6Z, 8Z-decatrienoic acid N-ethylamide
• 2E, 6Z, 8Z-decatrienoic acid-Nn-propylamide
• 2E, 6Z, 8Z-decatrienoic acid N-isopropylamide
• 2E, 6Z, 8Z-decatrienoic acid-Nn-butylamide
• 2E, 6Z, 8Z-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 6Z, 8Z-decatrienoic acid N-isobutylamide
• 2E, 6Z, 8Z-decatrienoic acid N-tert-butylamide
• 2E, 6E, 8Z-decatrienoic acid N-methylamide
• 2E, 6E, 8Z-decatrienoic acid N-ethylamide
• 2E, 6E, 8Z-decatrienoic acid-Nn-propylamide
• 2E, 6E, 8Z-decatrienoic acid N-isopropylamide
• 2E, 6E, 8Z-decatrienoic acid-Nn-butylamide
• 2E, 6E, 8Z-decatrienoic acid N- (1-methylpropyl) -amide
• 2E, 6E, 8Z-decatrienoic acid N-isobutylamide
• 2E, 6E, 8Z-decatrienoic acid N-tert-butylamide
• 2E, 7Z, 9E undecatrienoic acid N-methylamide
• 2E, 7Z, 9E undecatrienoic acid N-ethylamide
• 2E, 7Z, 9E-undecatrienoic acid-Nn-propylamide
• 2E, 7Z, 9E undecatrienoic acid N-isopropylamide
• 2E, 7Z, 9E-undecatrienoic acid-Nn-butylamide
• 2E, 7Z, 9E-undecatrienoic acid N- (1-methylpropyl) -amide
• 2E, 7Z, 9E undecatrienoic acid N-isobutylamide
• 2E, 7Z, 9E undecatrienoic acid N-tert-butylamide
• 2E, 7E, 9E undecatrienoic acid N-methylamide
• 2E, 7E, 9E undecatrienoic acid N-ethylamide
• 2E, 7E, 9E-undecatrienoic acid-Nn-propylamide
• 2E, 7E, 9E undecatrienoic acid N-isopropylamide
• 2E, 7E, 9E-undecatrienoic acid-Nn-butylamide
• 2E, 7E, 9E-undecatrienoic acid N- (1-methylpropyl) -amide
• 2E, 7E, 9E undecatrienoic acid N-isobutylamide
• 2E, 7E, 9E undecatrienoic acid N-tert-butylamide
• 2E, 7Z, 9Z-undecatrienoic acid N-methylamide
• 2E, 7Z, 9Z-undecatrienoic acid N-ethylamide
• 2E, 7Z, 9Z-undecatrienoic acid-Nn-propylamide
• 2E, 7Z, 9Z-undecatrienoic acid N-isopropylamide
• 2E, 7Z, 9Z-undecatrienoic acid-Nn-butylamide
• 2E, 7Z, 9Z-undecatrienoic acid N- (1-methylpropyl) -amide
• 2E, 7Z, 9Z-undecatrienoic acid N-isobutylamide
• 2E, 7Z, 9Z-undecatrienoic acid N-tert-butylamide
• 2E, 7Z, 9E undecatrienoic acid N-methylamide
• 2E, 7Z, 9E undecatrienoic acid N-ethylamide
• 2E, 7Z, 9E-undecatrienoic acid-Nn-propylamide
• 2E, 7Z, 9E undecatrienoic acid N-isopropylamide
• 2E, 7Z, 9E-undecatrienoic acid-Nn-butylamide
• 2E, 7Z, 9E-undecatrienoic acid N- (1-methylpropyl) -amide
• 2E, 7Z, 9E undecatrienoic acid N-isobutylamide
• 2E, 7Z, 9E undecatrienoic acid N-tert-butylamide

Of course Other substitution patterns on the nitrogen atom are also possible and preferably, for example, longer-chain n-alkyl radicals (...- N-n-pentylamide, ...- N-n-pentylamide, ...- N-n-pentylamide, ...- N-n-pentylamide, ...- N-n-pentylamide, ...- N-n-hexylamide, ...- N-n-heptylamide, ...- N-n-octylamide, ... -N-n-nonylamide, ...- N-n-decylamide, ...- N-n-undecylamide, ...- N-n-dodecylamide, ... N-n-tridecylamide, etc.) or disubstituted... N, N-dialkylamides such as... N, N-dimethylamide,... N, N-diethylamide,... N, N-di-n-propylamide, N, N-diisopropylamide, N, N-di-n-butylamide, N, N-di (1-methylpropyl) amide, N, N-diisobutylamide, N, N-di-tert-butylamide, N, N-methyl-ethylamide, N, N-methyl-n-propylamide, N, N-methyl-isopropylamide, N, N-ethyl-n-propylamide, N, N-ethyl-isopropylamide, etc.

2E,4E,8Z-Decatriensäure-N-isobutylamid (N-Isobutyl-2E,4E,8Z-decatrienamid, auch Isoaffinin genannt):

2E,7Z,9E-Undecatriensäure-N-isobutylamid (N-Isobutyl-2E,7Z,9E-undecatrienamid):

2E,4Z-Decadiensäure-N-isobutylamid (cis-Pellitorin):

2E,4E-Decadiensäure-N-isobutylamid (trans-Pellitorin):

Among the compounds mentioned, some are particularly preferred in the context of the present invention. These are listed below: 2E, 6Z, 8E-decatrienoic acid N-isobutylamide (N-isobutyl-2E, 6Z, 8E-decatrienamide, also called spilanthol or affinin):

2E, 4E, 8Z-Decatrienoic acid N-isobutylamide (N-isobutyl-2E, 4E, 8Z-decatrienamide, also called isoaffinin):

2E, 7Z, 9E-undecatrienoic acid N-isobutylamide (N-isobutyl-2E, 7Z, 9E-undecatrienamide):

2E, 4Z-decadienoic acid N-isobutylamide (cis-pellitorin):

2E, 4E-decadienoic acid N-isobutylamide (trans-pellitorin):

N-[2-(4-Hydroxy-3-methoxyphenynethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2E)-propensäureamid(trans-Feruloylmethoxytyramin):

N-[2-(4-Hydroxy-3-methoxyphenynethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2Z)-propensäureamid(cis-Feruloylmethoxytyramin):

N-[2-(4-Hydroxy-3-methoxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-propansäureamid (Dihydroferuloylmethoxytyramin):

N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2E)-propensäureamid (trans-Feruloyldopamin):

N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2Z)-propensäureamid (cis-Feruloyldopamin):

N-[2-(4-Hydroxyphenyl)ethyl]-3-(3,4-dihydroxyphenyl)-(2E)-propensäureamid (trans-Caffeoyltyramin):

N-[2-(4-Hydroxyphenynethyl]-3-(3,4-dihydroxyphenyl)-(2Z)-propensäureamid (cis-Caffeoyltyramin):

N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(3,4-dimethoxyphenyl)-(2E)-propensäureamid (trans-Rubenamin):

N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(3,4-dimethoxy-phenyl)-(2Z)-propensäureamid (cis-Rubenamin):

Ferulic acid amides, for example Ferulic acid N vanillylamide:

N- [2- (4-hydroxy-3-methoxyphenynethyl] -3- (4-hydroxy-3-methoxy-phenyl) - (2E) -propenoic acid amide (trans-feruloylmethoxytyramine):

N- [2- (4-hydroxy-3-methoxyphenynethyl] -3- (4-hydroxy-3-methoxy-phenyl) - (2 Z) -propenoic acid amide (cis-feruloylmethoxytyramine):

N- [2- (4-Hydroxy-3-methoxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) -propanoic acid amide (dihydroferuloylmethoxytyramine):

N- [2- (3,4-Dihydroxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) - (2E) -propenoic acid amide (trans -feruloyldopamine):

N- [2- (3,4-Dihydroxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) - (2Z) -propenoic acid amide (cis -feruloyldopamine):

N- [2- (4-Hydroxyphenyl) ethyl] -3- (3,4-dihydroxyphenyl) - (2E) -propenoic acid amide (trans-caffeoyltyramine):

N- [2- (4-Hydroxyphenynethyl) -3- (3,4-dihydroxyphenyl) - (2Z) -propenoic acid amide (cis-caffeoyltyramine):

N- [2- (3,4-Dimethoxyphenyl) ethyl] -3- (3,4-dimethoxyphenyl) - (2E) -propenoic acid amide (trans-Rubenamine):

N- [2- (3,4-dimethoxyphenyl) ethyl] -3- (3,4-dimethoxyphenyl) - (2Z) -propenoic acid amide (cis-Rubenamine):

Further in the context of the present invention can be used with particular preference For example, pungent substances are extracts from natural plants. Sharp Tasting herbal extracts can all be physiological be safe plant extracts that have a sharp or produce a warm sensory impression. Preferably as pungent-tasting vegetable extracts are, for example, pepper extract (Piper ssp. in particular Piper nigrum), water pepper extract (Polygonum ssp., in particular Polygonum hydropiper), extracts of Allium ssp. (especially Onion and garlic extracts), extracts of radish (Raphanus ssp.), Horseradish extracts (Cochlearia armoracia), extracts of black (Brassica nigra), wild or yellow mustard (Sinapis ssp., In particular Sinapis arvensis and Sinapis alba), Bertram root extracts (Anacyclus ssp., especially Anacyclus pyrethrum L.), sun hatch extracts (Echinaceae ssp.), extracts of Szechuan pepper (Zanthoxylum ssp., in particular Zanthoxylum piperitum), spilanthate extract (Spilanthes ssp., In particular Spilanthes acmella), chile extract (Capsicum ssp., Especially Capsicum frutescens), grains of paradise extract (Aframomum ssp, in particular Aframomum melegueta [Rose] K. Schum.), Ginger Extract (Zingiber ssp., Zingiber officinale in particular) and galangae extract (Kaempferia galanga or alpinia galanga).

A particularly suitable substance is the gingerol derived from the ginger extract:

It is also possible to use N-ethyl-p-menthane-3-carboxamide (N-ethyl-5-methyl-2-isopropylcyclohexanecarboxamide):

Other sharp-tasting or a feeling of heat-producing Substances can z. B. Capsaicin, Dihydrocapsaicin, Gingerol, paradole, shogaol, piperine, carboxylic acid N-vanillylamide, in particular nonanoic acid N-vanillylamide, 2-alkeneamides, in particular 2-nonenoic acid N-isobutylamide, 2-nonenoic acid N-4-hydroxy-3-methoxyphenylamide, Alkyl ethers of 4-hydroxy-3-methoxybenzyl alcohol, in particular 4-hydroxy-3-methoxybenzyl n-butyl ether, Alkyl ethers of 3-hydroxy-4-methoxybenzyl alcohol, alkyl ethers of 3,4-dimethoxybenzyl alcohol, Alkyl ethers of 3-ethoxy-4-hydroxybenzyl alcohol, alkyl ethers of 3,4-methylenedioxybenzyl alcohol, Nicotinaldehyde, methyl nicotinate, propyl nicotinate, 2-butoxyethyl nicotinate, Benzyl nicotinate, 1-acetoxychavicol, polygodial or isodrimeninol.

• – 2E,6Z,8E-Decatriensäure-N-isobutylamid (Spilanthol) und/oder
• – 2E,4E,8Z-Decatiensäure-N-isobutylamid und/oder
• – 2E,7Z,9E-Undecatriensäure-N-isobutylamid und/oder
• – 2E,4Z-Decadiensäure-N-isobutylamid (cis-Pellitorin) und/oder
• – 2E,4E-Decadiensäure-N-isobutylamid (trans-Pellitorin) und/oder
• – Ferulasäure-N-Vanillylamid und/oder
• – N-[2-(4-Hydroxy-3-methoxyphenynethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2E)-propensäureamid (trans-Feruloylmethoxytyramin) und/oder
• – N-[2-(4-Hydroxy-3-methoxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2Z)-propensäureamid (cis-Feruloylmethoxytyramin) und/oder
• – N-[2-(4-Hydroxy-3-methoxyphenynethyl]-3-(4-hydroxy-3-methoxy-phenyl)-propansäureamid (Dihydroferuloylmethoxytyramin) und/oder
• – N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2E)-propensäureamid (trans-Feruloyldopamin) und/oder
• – N-[2-(3,4-Dihydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)-(2Z)-propensäureamid (cis-Feruloyldopamin) und/oder
• – N-[2-(4-Hydroxyphenynethyl]-3-(3,4-dihydroxyphenyl)-(2E)-propensäureamid(trans-Caffeoyltyramin) und/oder
• – N-[2-(4-Hydroxyphenyl)ethyl]-3-(3,4-dihydroxyphenyl)-(2Z)-propensäureamid (cis-Caffeoyltyramin) und/oder
• – N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(3,4-dimethoxyphenyl)-(2E)-propensäureamid (trans-Rubenamin) und/oder
• – N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(3,4-dimethoxy-phenyl)-(2Z)-propensäureamid (cis-Rubenamin)

enthaltenParticularly preferred oral and dental care and cleaning agents according to the invention are characterized in that the suspended in the flowable carrier particles at least one Scharfstoff from the group of N-alkyl-substituted amides of unsaturated carboxylic acids, preferably

• 2E, 6Z, 8E-decatrienoic acid N-isobutylamide (Spilanthol) and / or
• 2E, 4E, 8Z-decatienoic acid N-isobutylamide and / or
• 2E, 7Z, 9E-undecatrienoic acid N-isobutylamide and / or
• 2E, 4Z-decadienoic acid N-isobutylamide (cis-pellitorin) and / or
• 2E, 4E-decadienoic acid N-isobutylamide (trans-pellitorin) and / or
• Ferulic acid N-vanillylamide and / or
• N- [2- (4-hydroxy-3-methoxyphenynethyl) -3- (4-hydroxy-3-methoxyphenyl) (2E) -propenoic acid amide (trans -feruloylmethoxytyramine) and / or
• N- [2- (4-hydroxy-3-methoxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) - (2Z) -propenoic acid amide (cis -feruloylmethoxytyramine) and / or
• N- [2- (4-hydroxy-3-methoxypheny nyl) -3- (4-hydroxy-3-methoxy-phenyl) -propanoic acid amide (dihydroferuloylmethoxy-tyramine) and / or
• N- [2- (3,4-dihydroxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) (2E) -propenoic acid amide (trans -feruloyldopamine) and / or
• N- [2- (3,4-dihydroxyphenyl) ethyl] -3- (4-hydroxy-3-methoxyphenyl) - (2Z) -propenoic acid amide (cis -feruloyldopamine) and / or
• N- [2- (4-hydroxyphenynethyl) -3- (3,4-dihydroxyphenyl) (2E) -propenoic acid amide (trans-caffeoyltyramine) and / or
• - N- [2- (4-hydroxyphenyl) ethyl] -3- (3,4-dihydroxyphenyl) - (2Z) -propenoic acid amide (cis-caffeoyltyramine) and / or
• N- [2- (3,4-dimethoxyphenyl) ethyl] -3- (3,4-dimethoxyphenyl) (2E) -propenoic acid amide (trans-Rubenamine) and / or
• N- [2- (3,4-dimethoxyphenyl) ethyl] -3- (3,4-dimethoxyphenyl) (2Z) -propenoic acid amide (cis-Rubenamine)

contain

at The preparation of the suspended particles may involve incorporation of active ingredients can be facilitated by the use of surfactants. These surfactants naturally remain in the particle. In addition, the particle suspension is stabilized by the surfactant, so that preferred oral and dental care and cleaning products are characterized that in the flowable carrier suspended particles - in relation to their weight - in addition 0.01 to 5 wt .-%, preferably 0.05 to 2.5 wt .-% and in particular 0.1 to 1 wt .-% surfactant (s) containing preferred surfactants selected are from fatty alcohol sulfates, especially sodium lauryl sulfate, and / or betaines, in particular cocoamidopropylbetaine.

Regarding the shape of the cellulosic particles in the suspension is the present invention not limited. Preferred are visually consistent, recurrent regular forms, such as for example, spheres, cuboids, polyhedra (Vielflächner) etc .. It is particularly preferred to design the particles such that they significantly larger in at least one spatial direction are as in the other two spatial directions. Here are inventive Oral and dental care and cleaning agents are preferred in which which suspended in the flowable carrier Particles are rod-shaped, d. H. in a spatial direction have an extent which is at least twice, preferably at least triple, especially preferred at least quadruple and in particular at least five times as large as the larger of the expansions in the other two Spatial directions.

preferred Forms of this embodiment are, for example, threads or long cylinders.

Another preferred geometric shape that the suspended particles can take is platy. Here oral and dental care and cleaning agents according to the invention are preferred in de The particles suspended in the flowable carrier are platelet-shaped, ie have an expansion in two spatial directions which is at least twice, preferably at least three times, more preferably at least four times and in particular at least five times as large as the extent in the other spatial direction.

In This embodiment may be planar Designs are realized. In addition to the shape of the "walkway slab" or "wall tile" (square or rectangle with a height, which is significantly smaller than the side lengths) can Circles, triangles, pentagons, hexagons, plus signs, rings etc. are selected. Even irregular forms like Trees, stars, animal shapes, clouds, letters, numbers, etc. are preferred. It is possible and preferred that not only particles of a design in the inventive Products, but several particle series with a variety of particles each having the same design, such as circles and rings.

Also in terms of size in the inventive Containing particles containing the invention is not limited subjected. Oral and dental care and cleaning agents are preferred, those in the flowable carrier suspended particles in the largest spatial Expansion lengths between 100 and 10,000 μm, preferably between 200 and 8000 microns, more preferably between 500 and 7000 μm and in particular between 1000 and 5000 microns.

The Oral and dental care and cleaning agents according to the invention usually contain other ingredients.

Prefers here is the use of so-called humectants, the prevent toothpaste from drying out. In so-called liquid tooth creams with flowable rheology these serve as a matrix and are used in higher amounts.

Here are inventive mouth and Zahnpflege- and -reinigungsmittel preferred, which - based on their weight - 10 to 60% by weight, preferably 12.5 to 50% by weight, more preferably 15 to 45 wt .-% and in particular 20 to 40 wt .-% of at least one polyhydric alcohol from the group of sorbitol and / or glycerol and / or 1,2-propylene glycol .-% contained.

beschreiben und kommt in Form farbloser, mäßig hygroskopischer, optisch aktiver Nadeln, welche sich leicht in Wasser lösen, in den Handel.Sorbitol (also called glucitol) is a sugar alcohol of glucose, which is a hexitol. Sorbitol can be prepared by hydrogenation of glucose, it breaks down intramolecularly relatively easily one or two molecules of water and forms cyclic ethers. Sorbitol can be expressed by the formula

describe and comes in the form of colorless, moderately hygroscopic, optically active needles, which dissolve easily in water, in the trade.

glycerin (1,2,3-propanediol, 1,2,3-trihydroxypropane, glycerol, oil sweet, INCI name: Glycerin, E 422) is a colorless, clear, heavy-moving, odorless, sweet-tasting, hygroscopic liquid that is miscible with water and alcohol in any ratio.

beschreiben. Die Herstellung von Glycerin erfolgte ursprünglich als Nebenprodukt der Fettverseifung. Die heutigen technischen Verfahren gehen von Propen aus, das über die Zwischenstufen Allylchlorid und Epichlorhydrin zu Glycerin verarbeitet wird. Ein weiteres technisches Verfahren ist die Hydroxylierung von Allylalkohol mit Wasserstoffperoxid am WO₃-Kontakt über die Stufe des Glycids.Glycerol can be defined by the formula

describe. The production of glycerin was originally as a by-product of fat saponification. Today's technical processes are based on propene, which is processed into glycerol via the intermediates allyl chloride and epichlorohydrin. Another technical process is the hydroxylation of allyl alcohol with hydrogen peroxide at the WO ₃ contact via the step of the glycide.

1,2-propylene glycol (1,2-propanediol) is a colorless and highly hygroscopic liquid, in any ratio with water and alcohols (such as methanol, Ethanol, propanols, butanols) is miscible. Technical 1,2-propanediol is a racemate of (-) - (R) - and (+) - (S) -1,2-propylene glycol. The preparation is carried out by direct hydrolysis of propylene oxide. Because 1,2-P. reacted further with propylene oxide, thereby forming a mixture of 1,2- and tripropylene glycol, which are separated by distillation got to. 1,2-propylene glycol can also be made from renewable raw materials three different routes are produced: a) catalytic Hydrogenation of sugars; b) Fermentation of sugars to lactic acid and then hydrogenation of the lactic acid ester; c) direct fermentation of sugars.

For certain applications may be advantageous, only one use of the three ingredients mentioned above. In most Cases sorbitol is preferred. However, you can in other applications mixtures of two of the three substances or of all three substances. Particularly advantageous Here is a mixture of glycerol, sorbitol and 1,2-propylene glycol in a weight ratio of 1: (0.5-1) :( 0.1-0.5) proved.

Next Sorbitol or glycerol or 1,2-propylene glycol are suitable as further polyhydric alcohols such having at least 2 OH groups, preferably Mannitol, xylitol, polyethylene glycol, polypropylene glycol and theirs Mixtures.

Under These compounds are those having 2 to 12 OH groups and in particular those with 2, 3, 4, 5, 6 or 10 OH groups are preferred.

Polyhydroxy compounds having 2 OH groups are, for example, glycol (CH ₂ (OH) CH ₂ OH) and other 1,2-diols such as H- (CH ₂ ) _n -CH (OH) CH ₂ OH where n = 2, 3, 4 , 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20. Also 1,3-diols such as H- (CH ₂ ) _n -CH ( OH) CH ₂ CH ₂ OH with n = 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 used according to the invention. The (n, n + 1) or (n, n + 2) diols with non-terminal OH groups can also be used.

Important Representatives of polyhydroxy compounds having 2 OH groups are also the polyethylene and polypropylene glycols.

When preferred further polyhydric alcohols may, for. Xylitol, Propylene glycols, polyethylene glycols, especially those with medium Molecular weights of 200-800 are used.

Especially preferred is the use of sorbitol, so that means that contain no other polyhydric alcohols other than sorbitol, are particularly preferred.

Of the Use of cleaning agents (abrasives) is also preferred. Cleaning bodies are amorphous, predominantly inorganic, largely water-insoluble, very small-particle powder, the have no sharp edges. They favor tooth and oral care products cleaning the teeth and polishing at the same time the tooth surface (polish).

When Polishing agents are in principle all suitable for toothpastes known friction body, in particular those which do not contain calcium ions contain. Preferably suitable polishing agent components are therefore Silicas, aluminum hydroxide, alumina, sodium aluminosilicates, organic polymers or mixtures of such friction bodies.

calcium-containing Polishing components such. Chalk, calcium pyrophosphate, dicalcium phosphate dihydrate but in amounts up to 5 wt .-% - related on the overall composition - be included.

Of the Total content of polishing agents is preferably in the range of 5-50% by weight of the dentifrice.

Toothpastes and liquid dentifrices containing silicic acids as a polishing agent are particularly preferred. Suitable silicas are, for. As gel silicas, hydrogel silicic acids and precipitated silicas. Gel silicas are prepared by reacting sodium silicate solutions with strong, aqueous mineral acids to form a hydrosol, aging to the hydrogel, washing and drying. If the drying takes place under mild conditions to water contents of 15 to 35 wt .-%, the so-called hydrogel silicas are obtained. Drying to water contents below 15% by weight results in an irreversible shrinkage of the previously loose structure of the hydrogel to the dense structure of the so-called Xerogel.

A second, preferably suitable group of silica polishing agents are the precipitated silicas. These are obtained by precipitation of silica from dilute alkali silicate solutions by addition of strong acids under conditions in which aggregation to the sol and gel can not occur. Suitable methods for preferably suitable is a precipitated silica having a BET surface area of 15-110 m ² / g, a particle size of 0.5-20 microns, wherein at least 80 wt .-% of the primary particles should be less than 5 microns, and a viscosity in 30% glycerol-water (1: 1) dispersion of 30-60 Pa.s (20 ° C) in an amount of 10-20% by weight of the dentifrice. Particularly suitable precipitated silicas of this type have rounded corners and edges and are commercially available under the trade name ^® Sident 12 DS (DEGUSSA).

Other precipitated silicas of this type are ident ^® 8 (DEGUSSA) and Sorbosil® ^® AC 39 (Crosfield Chemicals). These silicas are characterized by a lower thickening effect and a slightly higher average particle size of 8-14 microns at a specific surface area of 40-75 m ² / g (according to BET) and are particularly suitable for liquid toothpastes. These should have a viscosity (25 ° C, shear rate D = 10 s ^-1 ) of 10-100 Pa · s.

On the other hand, toothpastes which have a significantly higher viscosity of more than 100 Pa.s (25 ° C., D = 10 s ^-1 ) require a sufficiently high proportion of silicas having a particle size of less than 5 μm, preferably at least 3% by weight. -% of a silica with a particle size of 1-3 microns. Such toothpastes are therefore preferably used in addition to the precipitated silicas mentioned finely divided, so-called thickening silicic acids having a BET surface area of 150-250 m ² / g, z. As the commercial products Sipernat 22 LS or Sipernat ^® 320 DS.

When further polish component can also z. B. alumina in Form of slightly calcined clay containing and Contain alumina in an amount of about 1-5 wt .-% be. Such a suitable alumina is under the trade name "Poliertonerde P10 finest" (Giulini Chemie) available.

When Polishes are also all known for toothpastes Reibkörper such. B. sodium aluminum silicates such. B. Zeolite A, organic polymers such. As polymethacrylate or mixtures this and the aforementioned friction body.

In summary, agents according to the invention are those which additionally have cleaning bodies, preferably silicic acids, aluminum hydroxide, aluminum oxide, calcium pyrophosphate, chalk, dicalcium phosphate dihydrate (CaHPO ₄ .2H ₂ O), sodium aluminum silicates, in particular zeolite A, organic polymers, in particular polymethacrylates or mixtures of these friction bodies, preferably in quantities from 1 to 30 wt .-%, preferably from 2.5 to 25 wt .-% and in particular from 5 to 22 wt .-%, each based on the total agent included.

The indicated quantities refer to the total amount of friction bodies, wherein individual friction body preferably in narrower ranges be used. According to the invention preferred Agents contain, for example, 5 to 20% by weight, preferably 8 to 21 wt .-%, more preferably 9 to 20 wt .-% and in particular 11 to 19% by weight of silica (s). Further preferred inventive Means are characterized by being 0.25 to 2 Wt .-%, preferably 0.5 to 1.5 wt .-% and in particular 0.75 to Contain 1.25 wt .-% alumina.

Mouth- and dentifrices and cleaning agents, in particular toothpastes z. B. also contain substances that are resistant to plaque and / or tartar are effective.

plaque (Plaque) is a rough, sticky coating on the teeth, which consists of saliva, bacteria and food residues. Sit down Mineral salts (eg calcium, phosphate) from the saliva in the dental plaque, thus hard, white or yellowish deposits form on the tooth called tartar. In the porous calculus In turn, plaque can easily settle on the gums attacks.

The bacteria on the tooth surface reduce carbohydrates, especially sugars, from food to acid. This acid dissolves the tooth substance and it comes to tooth decay (tooth rot). In particular, the minerals calcium and phosphate are extracted from the enamel. After the enamel coat also inner layers of the tooth are attacked. Bacteria can invade the pulp and lead there to inflammation. Mostly it comes then to stinging toothache.

As already mentioned, plaque involves bacteria, so that are suitable for controlling plaque antimicrobial substances. These also have an effect as a preservative.

In For example, mouth and teeth care and cleaners can the preservative also approved in foodstuffs sorbic acid (E 200), potassium sorbate (E 202), calcium sorbate (E 203), benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212), calcium benzoate (E 213), ethyl 4-hydroxybenzoate (E 214), ethyl 4-hydroxybenzoate, Sodium salt (E 215), propyl 4-hydroxybenzoate (E 216), propyl 4-hydroxybenzoate, Sodium salt (E 217), methyl 4-hydroxybenzoate (E 218), methyl 4-hydroxybenzoate, Sodium salt (E 219), sulfur dioxide (sulphurous acid), (E 220), sodium sulfite (E 221), sodium hydrogen sulfite (E 222), sodium disulfite (E 223), potassium bisulfite (E 224), calcium sulfite (E 226), calcium hydrogen sulfite (E 227), potassium hydrogen sulfite (E 228), biphenyl (E 230), orthophenylphenol (2-biphenylol), (E 231), sodium orthophenylphenolate (E 232), nisin (E 234), natamycin (E 235), formic acid (E 236), sodium formate (E 237), calcium formate (E 238), hexamethylenetetramine (E 239), dimethyl dicarbonate (E 242), potassium nitrite (E 249), sodium nitrite (E 250), sodium nitrate (E 251), potassium nitrate (E 252), acetic acid (E 260), potassium acetate (E 261), sodium acetate (E 262), calcium acetate (E 263), lactic acid (E 270), propionic acid (E 280), sodium propionate (E 281), Calcium propionate (E 282), potassium propionate (E 283), boric acid (E 284), sodium tetraborate (E 285), malic acid (Malic acid), (E 296), fumaric acid (E. 297), lysozyme (E 1105).

preferred Substances are selected from p-hydroxybenzoic acid methyl, ethyl or propyl ester, sodium sorbate, sodium benzoate, bromochlorophen, Triclosan, phenyl salicylic acid esters, biguanides z. B. Chlorhexidine (1,1'-hexamethylenebis [5- (4-chlorophenyl) biguanide), Thymol etc.

According to the invention preferred Agents additionally contain antiplaque agents, preferably p-hydroxybenzoic acid methyl, ethyl or propyl ester, Sodium sorbate, sodium benzoate, bromochlorophene, triclosan, phenyl Salicylic acid esters, biguanides z. Chlorhexidine, thymol, preferably in amounts of 0.1 to 5 wt .-%, preferably of 0.25 to 2.5 wt .-% and in particular from 0.5 to 1.5 wt .-%, respectively based on the total mean.

The indicated amounts refer to the total amount of antiplaque agents, wherein individual active ingredients preferably in narrower ranges be used. Preferred agents according to the invention contain, for example, 0.1 to 2 wt .-%, preferably 0.2 to 1.75 wt .-%, more preferably 0.3 to 1.5 wt .-% and in particular 0.4 to 1.0% by weight of sodium benzoate. Further preferred inventive Means are characterized by being 0.005 to 0.1 Wt .-%, preferably 0.01 to 0.075 wt .-% and in particular 0.02 contain up to 0.05 wt .-% chlorhexidine. Chlorhexidine is preferably used together with alkyl polyglycosides (APG), wherein in preferred agents according to the invention as alkyl glycosides such with 8-18 C atoms in the alkyl group and a medium degree of oligomerization of the glycoside residue of 1-3 in an amount of 0.025 to 2.5 wt .-% are included.

Anti-calculus substances may be, for example, chelating agents such. As ethylenediaminetetraacetic acid and its sodium salts, pyrophosphate salts such as the water-soluble dialkali or Tetraalkalimetallpyrophosphat- salts, z. B. Na ₄ P ₂ O ₇ , K ₄ P ₂ O ₇ , Na ₂ K ₂ P ₂ O ₇ , Na ₂ H ₂ P ₂ O ₇ and K ₂ H ₂ P ₂ O ₇ or polyphosphate salts, the z. B. from water-soluble Alkalimethalltripolyphosphaten as sodium tripolyphosphate and potassium tripolyphosphate can be selected.

According to the invention preferred Means are characterized in that they additionally Phosphate (s), preferably alkali metal phosphate (s) and in particular Sodium tripolyphosphate, preferably in amounts of from 1 to 10% by weight, particularly preferably from 2 to 8% by weight and in particular from 3 to 7 wt .-%, each based on the total agent included.

mouth and dental care and cleaning agents can do about it In addition, anticaries drugs are particularly preferred. These For example, they can be organic or inorganic Be selected fluorides, for. B. from sodium fluoride, potassium fluoride, Sodium monofluorophosphate and sodium fluorosilicate. Also zinc fluoride, Tin (II) fluoride is preferred. Preferred should be a lot of 0.01-0.2% by weight of fluorine in the form of the compounds mentioned be included.

Compositions according to the invention which additionally contain anti-caries agents, preferably fluorine compound (s), in particular sodium fluoride, potassium fluoride, sodium monofluorophosphate, zinc fluoride, tin fluoride and sodium fluorosilicate, preferably in amounts of from 0.01 to 5% by weight, preferably from 0.1 to 2, 5 wt .-% and ins particular from 0.2 to 1.1 wt .-%, each based on the total agent, are preferred according to the invention.

As a consistency regulator (or binder) serve z. As natural and / or synthetic water-soluble polymers such as alginates, carrageenan, tragacanth, starch and starch ethers, cellulose ethers such. As carboxymethyl cellulose (Na salt), hydroxyethyl cellulose, methyl hydroxypropyl cellulose, guar, Akaziengum, agar-agar, xanthan gum, succinoglycan gum, locust bean flour, pectins, water-soluble carboxyvinyl polymers (eg. Carbopol ^® types), polyvinyl alcohol, polyvinyl pyrrolidone, Polyethylene glycols, in particular those having molecular weights of 1 500-1 000 000.

Further Substances suitable for viscosity control are z. B. phyllosilicates such. B. montmorillonite clays, colloidal Thickening silicas such. B. airgel silicas, pyrogenic silicic acids or finely ground precipitated silicas. It can also viscosity stabilizing additives from the group of cationic, zwitterionic or ampholytic nitrogen-containing surfactants, the hydroxypropyl-substituted hydrocolloids or the polyethylene glycol / polypropylene glycol copolymers having a average molecular weight of 1000 to 5000 or a combination of mentioned compounds are used in the toothpastes.

Also Surfactants are in the toothpastes for Support the cleaning effect and if desired also for the development of foam during tooth brushing and for stabilizing the polishing body dispersion in Contain carrier in an amount of 0.15 wt .-%.

Suitable surfactants are, for. B. linear sodium alkyl sulfates having 12-18 C atoms in the alkyl group. These substances additionally have an enzyme-inhibiting effect on the bacterial metabolism of the dental plaque. Further suitable surfactants are alkali metal salts, preferably sodium salts of alkylpolyglycol ether sulfate having 12-16 C atoms in the linear alkyl group and 2-6 glycol ether groups in the molecule, of linear alkane (C ₁₂ -C ₁₈ ) sulfonate, of sulfosuccinic acid monoalkyl (C ₁₂ -C ₁₈ ) esters of sulfated fatty acid monoglycerides, sulfated fatty acid alkanolamides, sulfoacetic acid alkyl (C ₁₂ -C ₁₆ ) esters, acylsarcosines, acyl taurides and acyl isothionates each having 8-18 C atoms in the acyl group. Also zwitterionic, ampholytic and nonionic surfactants are suitable, for. B. Oxethylates of fatty acid mono- and diglycerides, of fatty acid sorbitan esters and alkyl (oligo) glucosides.

The Oral and dental care products, in particular the toothpastes, can also the insensitivity of the teeth-increasing substances contain, for example, potassium salts such. Potassium nitrate, potassium citrate, potassium chloride, Potassium bicarbonate and potassium oxalate. According to the invention preferred Means are characterized by their insensitivity the teeth-enhancing substances, preferably potassium salts, particularly preferably potassium nitrate and / or potassium citrate and / or Potassium chloride and / or potassium bicarbonate and / or potassium oxalate, preferably in amounts of 0.5 to 20 wt .-%, particularly preferably from 1.0 to 15 wt .-%, more preferably from 1.5 to 5 wt .-% and in particular from 1.75 to 2.5% by weight, based in each case on the total agent, contain.

Especially preferred mouth and dental care and cleaning agents contain 0.5 to 9.5 wt .-%, preferably 1 to 9 wt%, more preferably 2 to 8 wt%, even more preferably 3 to 7 wt .-% and in particular 4 to 6 wt .-% potassium salt (s).

The agents according to the invention, in particular toothpastes, can also have additional wound healing and anti-inflammatory substances, eg. B. agents for gingivitis, contain. Such substances may, for. B. selected from allantoin, azulene, chamomile extracts, tocopherol, panthenol, bisabolol, Sage extracts.

When non-cationic, bactericidal component are suitable for. Phenols, Resorcinols, bisphenols, salicylanilides and their halogenated derivatives, halogenated carbanilides and p-hydroxybenzoic acid esters. Particularly preferred antimicrobial components are halogenated Diphenyl ether, e.g. B. 2,4-dichloro-2'-hydroxydiphenyl ether, 4,4'-dichloro-2'-hydroxydiphenyl ether, 2,4,4'-tribromo-2'-hydroxydiphenyl ether and 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). They are preferred in amounts of 0.01-1 % By weight in the dentifrices according to the invention used. Triclosan is particularly preferred in an amount of 0.01-0.3 wt .-% used.

D-panthenol D - (+) - 2,4-dihydroxy-N- (3-hydroxypropyl) -3,3-dimethyl-butyramide exhibits a biological activity corresponding to pantothenic acid. The pantothenic acid (R - (+) - N- (2,4-dihydroxy-3,3-dimethylbuty ryl-β-alanine) is a precursor in the biosynthesis of coenzyme A and is counted to the vitamin B complex (B3). These substances are known to promote wound healing and have a beneficial effect on the skin. They have therefore also been occasionally described in toothpastes. The dentifrices according to the invention preferably contain 0.05-5% by weight of panthenol or a salt of pantothenic acid.

Retinol (3,7-dimethyl-9- (2,6,6-trimethyl-1-cyclohexenyl) -2,4,6,8-nonatetraen-1-ol is the international common name for vitamin A1, but may also be used instead of retinol one of its derivatives having a similar biological activity, for example an ester or the retinoic acid (tretinoin), one of its salts or its esters is preferably used, a retinol ester, in particular a fatty acid ester of a fatty acid having 12-22 C atoms Retinol palmitate is particularly preferably used When using a retinol ester, for example retinol palmitate with an activity of 1.7 × 10 ⁶ IU per g, an amount of 0.001 to 0.1% by weight is preferred When using other retinol derivatives, an amount of use corresponding to a concentration of 10 ³ to 10 ⁶ IU (International Units) per 100 g is recommended Preferred dentifrices according to the present invention include, in addition to polishing agents, fluorine compounds, humectants and binders
0.01-1 wt .-% of a halogenated diphenyl ether
0.05-5 wt.% Panthenol or a salt of pantothenic acid and
0.01-0.1% by weight of a retinol ester, preferably retinol palmitate.

The agents according to the invention, in particular toothpastes, may also contain substances to increase the mineralizing Potentials include, for example, calcium-containing substances such as z. Calcium chloride, calcium acetate and dicalcium phosphate dihydrate. The concentration of the calcium-containing substance depends on the solubility of the substance and the interaction with other substances contained in the oral and dental care products from.

Next the said compulsory components, the inventive Dentifrices other, known per se auxiliaries and additives contain. This is an additive that serves as a toothpaste component has long been known in the inventive Dentifrices particularly effective: calcium glycerophosphate, the Calcium salt of glycerol-1-phosphoric acid or glycerol-2-phosphoric acid or the glycerol-1-phosphoric acid enantiomeric glycerol-3-phosphoric acid - or a mixture of these acids. The compound has in dentifrices a remineralizing effect as it contains both calcium and calcium Provides phosphate ions. In the invention Dentifrices are preferred in quantities of calcium glycerophosphate 0.01-1 wt .-% used. Overall, you can the dentifrices according to the invention usual Auxiliaries and additives in amounts up to 10 wt .-% included.

The Dentifrices according to the invention can z. B. by the addition of aromatic oils and sweeteners be improved in their organoleptic properties.

When Aromatic oils can all be used for oral and Dentifrices usual natural and synthetic flavors be used. Natural flavors can be both in the form of natural essential oils isolated from drugs and the individual components isolated therefrom.

suitable Flavors are z. B. peppermint oil, spearmint oil, Eucalyptus oil, aniseed oil, fennel oil, caraway oil, menthyl acetate, Cinnamaldehyde, anethole, vanillin, thymol and mixtures of these components.

suitable Sweeteners are z. Saccharin sodium, sodium cyclamate, Sucrose, lactose, meltose, fructose.

• – Oberflächenaktive Stoffe, bevorzugt anionische, zwitterionische, amphotere, nicht-ionische Tenside oder eine Kombination mehrerer verschiedener Tenside
• – Lösungsmittel und Lösungsvermittler, z. B. niedere einwertige oder mehrwertige Alkohole oder Ether, z. B. Ethanol, 1,2-Propylenglycol, Diethylenglycol oder Butyldi-glycol
• – Pigmente, wie z. B. Titandioxid
• – Farbstoffe
• – Puffersubstanzen, z. B. primäre, sekundäre oder tertiäre Alkaliphosphate oder Citronen-säure-/Na-Citrat
• – weitere wundheilende oder entzündungshemmende Stoffe, z. B. Allantoin, Harnstoff, Azulen, Kamillewirkstoffe, Acetylsalicylsäurederivate oder Rhodanid
• – weitere Vitamine wie z. B. Ascorbinsäure, Biotin, Tocopherol oder Rutin
• – Mineralsalze wie z. B. Mangan-, Zink- oder Magnesiumsalze.

Further customary auxiliaries and additives for toothpastes are

• - Surface-active substances, preferably anionic, zwitterionic, amphoteric, nonionic surfactants or a combination of several different surfactants
• - Solvents and solubilizers, eg. As lower monohydric or polyhydric alcohols or ethers, for. For example, ethanol, 1,2-propylene glycol, diethylene glycol or butyl di-glycol
• - pigments, such as. For example, titanium dioxide
• - Dyes
• - Buffer substances, for. As primary, secondary or tertiary alkali metal phosphates or citric acid / Na citrate
• - other wound-healing or anti-inflammatory substances, eg. Allantoin, urea, azulene, chamomile agents, acetylsalicylic acid derivatives or rhodanide
• - other vitamins such. As ascorbic acid, biotin, tocopherol or rutin
• - Mineral salts such. For example, manganese, zinc or magnesium salts.

A another important group of ingredients used in the invention Agents that can be included are the so-called bioactive glasses.

Of the Term "bioactive glasses" includes in Within the scope of the present application glasses which are biologically are active and / or biologically active. The biological effectiveness For example, a glass can be found in its antimicrobial Properties show biologically active glass is different of conventional lime-sodium-silicate glasses in that it binds living tissue. Biologically active For example, glass refers to a glass that has a strong bond with body tissue, wherein a hydroxyl apatite layer is trained. Bioactive glass is also understood to mean a glass, the antimicrobial and / or anti-inflammatory effect shows. The glass powders show bacteria, fungi as well as viruses a biocidal or a biostatic effect; are in Contact with humans skin-friendly, toxicological harmless and especially suitable for consumption.

Particularly according to the invention preferred agents are characterized in that they 0.2 to 20 wt .-%, preferably 0.4 to 14 wt .-%, particularly preferably 0.5 to 3 wt .-% and in particular 0.6 to 2 wt .-% of at least one contain bioactive glass.

The Oral and dental care and cleaning agents according to the invention This embodiment contains bioactive glass or glass powder or glass ceramic powder or composite materials, which one include bioactive glass. Under glass powders are under the present application also granules and glass beads Understood.

by virtue of the requirements for the toxicological safety of the glass as well as their suitability for consumption the glass powder should be particularly pure be. The burden of heavy metals is preferably low. Thus, the maximum concentration in the field of cosmetic Formulations preferably for Pb <20 ppm, Cd <5 ppm, As <5 ppm, Sb <10 ppm, Hg <1 ppm, Ni <10 ppm.

The unfused starting glass, which is contained directly in the preferred compositions according to the invention or is optionally used for the production of a glass ceramic which can be used according to the invention, contains SiO ₂ as a network former, preferably between 35-80% by weight. At lower concentrations, the spontaneous tendency to crystallize increases greatly and the chemical resistance decreases sharply. At higher SiO ₂ values, the crystallization stability may decrease and the processing temperature is significantly increased, so that the hot-forming properties deteriorate. Na ₂ O is used as a flux when melting the glass. At concentrations of less than 5%, the melting behavior is adversely affected. Sodium is a constituent of the phases which form during the ceramization and, if high crystalline phase fractions are to be adjusted by the ceramization, must be present in the glass in correspondingly high concentrations. K ₂ O acts as a flux when melting the glass. In addition, potassium is released in aqueous systems. If high potassium concentrations are present in the glass, potassium-containing phases such as calcium silicates are also eliminated. The P ₂ O ₅ content of silicate glasses, glass ceramics or composites can be used to adjust the chemical resistance of the glass and thus the ion emission in aqueous media. For Phospaht glasses, P ₂ O _{5 is} network images. The P ₂ O ₅ content is preferably between 0 and 80 wt .-%. In order to improve the meltability, the glass may contain up to 25% by weight of B ₂ O ₃ . Al ₂ O ₃ is used to adjust the chemical resistance of the glass.

to Reinforcement of antimicrobial, especially antibacterial Properties of the glass ceramic can have antimicrobial properties Ions such. B. Ag, Au, I, Ce, Cu, Zn in concentrations smaller Be contained 5 wt .-%.

coloring Ions such. Mn, Cu, Fe, Cr, Co, V, may be singly or combined, preferably in a total concentration less than 1 Wt .-%, be contained.

Usually the glass or the glass ceramic is used in powder form. The Ceramization can either be done with a glass block or glass ribbons done or with glass powder. After the ceramization must the glass ceramic blocks or ribbons are ground to powder. If the powder has been ceramized, it may also have to be re-used are ground to agglomerates, which formed during the ceramization step are to remove. The grindings can be both dry as well as in aqueous or non-aqueous milling media be performed. Usually they are Particle sizes smaller than 500 μm. As appropriate have particle sizes <100 microns or <20 microns proved. Particularly suitable are particle sizes <10 microns as well as smaller 5 μm as well as smaller 2 μm, see further below.

The in the preferred compositions of the invention contained bioactive glasses or

Glass powders or glass ceramic powders or composite compositions comprise glasses which preferably comprise the following components: SiO ₂ : 35-80% by weight, Na ₂ O: 0-35% by weight, P ₂ O ₅ : 0-80% by weight. %, MgO: 0-5 wt%, Ag ₂ O: 0-0.5 wt%, AgJ: 0-0.5 wt%, NaJ: 0-5 wt%, TiO ₂ : 0-5 wt%, K ₂ O: 0-35 wt%, ZnO: 0-10 wt%, Al ₂ O ₃ : 0-25 wt%, and B ₂ O ₃ : 0 -25% by weight.

Furthermore, the base glass according to the above composition to achieve further effects such as color or UV filtering ions such as Fe, Co, Cr, V, Ce, Cu, Mn, Ni, Bi, Sn, Ag, Au, J individually or in total to be added to 10 wt .-%. A further glass composition may be as follows: SiO ₂ : 35-80 wt%, Na ₂ O: 0-35 wt%, P ₂ O ₅ : 0-80 wt%, MgO: 0-5 wt %, Ag ₂ O: 0-0.5 wt%, AgJ: 0-0.5 wt%, NaJ: 0-5 wt%, TiO ₂ : 0-5 wt% , K ₂ O: 0-35 wt .-%, ZnO: 0-10 wt .-%, Al ₂ O ₃ : 0-25 wt .-%, B ₂ O ₃ : 0-25 wt .-%, SnO : 0-5 wt%, CeO ₂ : 0-3 wt%, and Au: 0.001-0.1 wt%.

Particularly preferred oral and dental care and cleaning agents according to the invention are characterized in that the bioactive glass - based on its weight - has the following composition: SiO ₂ From 35 to 60% by weight, preferably 40 to 60% by weight, Na ₂ O 0 to 35% by weight, preferably From 5 to 30% by weight, K ₂ O 0 to 35% by weight, preferably 0 to 20% by weight, P ₂ O ₅ 0 to 10% by weight, preferably From 2 to 10% by weight, MgO 0 to 10% by weight, preferably 0 to 5% by weight, CaO 0 to 35% by weight, preferably From 5 to 30% by weight, Al ₂ O ₃ 0 to 25% by weight, preferably 0 to 5% by weight, B ₂ O ₃ 0 to 25% by weight, preferably 0 to 5% by weight, TiO ₂ 0 to 10% by weight, preferably 0.1 to 5 wt .-%.

As already mentioned above, the bioactive glass is preferably used in particulate form.

Here are particularly preferred oral and dental care and cleaning agent characterized in that the antimicrobial glass particle sizes <10 μm, preferably from 0.5 to 4 .mu.m, more preferably from 1 to 2 microns, has.

QUOTES INCLUDE IN THE DESCRIPTION

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Cited patent literature

• WO 2005/058265 A1 [0010]

Claims (15)

Oral and dental care and cleaning compositions, comprising a flowable carrier and particles suspended therein, characterized in that a) the flowable carrier - based on its weight - contains at least 5 wt .-% water, and b) suspended in the flowable carrier Particles - based on their weight - contain at least 70 wt .-% cellulose. Oral and dental care and cleaning agents after Claim 1, characterized in that the flowable Carrier - based on its weight - at least 10% by weight, preferably at least 20% by weight, more preferably at least 30% by weight, more preferably at least 40% by weight, and especially at least 50 wt .-% water. Oral and dental care and cleaning agents after one of claims 1 or 2, characterized in that the suspended in the flowable carrier Particles - based on their weight - 0.01 to 20 wt .-% perfume (s) and / or flavorings. Oral and dental care and cleaning agents after one of claims 1 to 3, characterized in that the suspended in the flowable carrier Particles - based on their weight - 0.05 to 19 wt .-%, preferably 0.1 to 18 wt .-%, particularly preferably 0.5 to 17 wt .-%, more preferably 0.75 to 16 wt .-% and in particular 1 to 15% by weight of at least one flavor from the group of peppermint, Spearmint, Menthol, Lime, Lime, Apple, Orange, Lemon, Strawberry, Aloe vera, containing chewing gum. Oral and dental care and cleaning agents after one of claims 1 to 4, characterized in that the suspended in the flowable carrier Particles - in relation to their weight - additionally 0.01 to 5 wt .-%, preferably 0.05 to 2.5 wt .-% and in particular 0.1 to 1 wt .-% surfactant (s) containing preferred surfactants selected are from fatty alcohol sulfates, especially sodium lauryl sulfate, and / or betaines, in particular cocoamidopropylbetaine. Oral and dental care and cleaning agents after one of claims 1 to 5, characterized in that the suspended in the flowable carrier Particles are rod-shaped, d. H. in one spatial direction one Have expansion that at least twice, preferably at least three times, more preferably at least four times and in particular at least five times the size of the larger one the expansions in the other two spatial directions. Oral and dental care and cleaning agents after one of claims 1 to 5, characterized in that the suspended in the flowable carrier Particles are platelet-shaped, d. H. in two directions one Have expansion that at least twice, preferably at least three times, more preferably at least four times and in particular at least five times the size of the extension in the other spatial direction. Oral and dental care and cleaning agents after one of claims 1 to 7, characterized in that the suspended in the flowable carrier Particles in the largest spatial extent Lengths between 100 and 10,000 μm, preferably between 200 and 8000 microns, more preferably between 500 and 7000 microns and in particular between 1000 and 5000 microns exhibit. Mouth and teeth care and cleanser after one of claims 1 to 8, characterized in that it 0.5 to 9.5 wt%, preferably 1 to 9 wt%, more preferably 2 to 8 wt .-%, more preferably 3 to 7 wt .-% and in particular 4 to 6 wt .-% potassium salt (s). Mouth and teeth care and cleanser after one of claims 1 to 9, characterized in that - related on its weight - 10 to 60 wt .-%, preferably 12.5 to 50 wt .-%, particularly preferably 15 to 45 wt .-% and in particular 20 to 40 wt .-% of at least one polyhydric alcohol from the Group sorbitol and / or glycerol and / or 1,2-propylene glycol .-% contains. Oral and dental care and cleaning agent according to one of claims 1 to 10, characterized in that it additionally cleaning body, preferably silicic acid, aluminum hydroxide, alumina, calcium pyrophosphate, chalk, dicalcium phosphate dihydrate (CaHPO ₄ · 2H ₂ O), sodium aluminum silicates, in particular Zeolite A, organic polymers, in particular polymethacrylates or mixtures of these friction bodies, preferably in amounts of 1 to 30 wt .-%, preferably from 2.5 to 25 wt .-% and in particular from 5 to 22 wt .-%, each based on the total agent contains. Oral and dental care and cleaning agents after one of claims 1 to 11, characterized in that it additionally phosphate (s), preferably alkali metal phosphate (s) and especially sodium tripolyphosphate, preferably in amounts from 1 to 10 wt .-%, particularly preferably from 2 to 8 wt .-% and in particular from 3 to 7 wt .-%, each based on the total agent contains. Oral and dental care and cleaning agents after one of claims 1 to 12, characterized in that it additionally antiplaque agents, preferably methyl p-hydroxybenzoate, ethyl or propyl ester, sodium sorbate, sodium benzoate, bromochlorophen, Triclosan, hexetidines, phenyl salicylic acid esters, biguanides z. As chlorhexidine, thymol, preferably in amounts of 0.05 to 5 wt .-%, preferably from 0.10 to 2.5 wt .-% and in particular from 0.30 to 1.5% by weight, based in each case on the total agent, contains. Oral and dental care and cleaning agents after one of claims 1 to 13, characterized in that it additionally anticaries drugs, preferably fluorine compound (s), especially sodium fluoride, potassium fluoride, sodium monofluorophosphate, Zinc fluoride, stannous fluoride and sodium fluorosilicate, preferably in amounts of from 0.01 to 5% by weight, preferably from 0.1 to 2.5% by weight and in particular from 0.2 to 1.1 wt .-%, each based on the entire means, contains. Oral and dental care and cleaning agents after one of claims 1 to 14, characterized in that it 0.2 to 20 wt .-%, preferably 0.4 to 14 wt .-%, particularly preferably 0.5 to 3 wt .-% and in particular 0.6 to 2 wt .-% of at least one contains bioactive glass.