DE102005014334A1 - Preparing hypnotic/sedative, psychopharmacologic drugs/anti-depressive and anxiolytic, for clarifying and strengthening the mind, comprises adding myrrh tincture and wine, mixing sweet wood root juice with mixture and agitating - Google Patents

Preparing hypnotic/sedative, psychopharmacologic drugs/anti-depressive and anxiolytic, for clarifying and strengthening the mind, comprises adding myrrh tincture and wine, mixing sweet wood root juice with mixture and agitating Download PDF

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DE102005014334A1
DE102005014334A1 DE102005014334A DE102005014334A DE102005014334A1 DE 102005014334 A1 DE102005014334 A1 DE 102005014334A1 DE 102005014334 A DE102005014334 A DE 102005014334A DE 102005014334 A DE102005014334 A DE 102005014334A DE 102005014334 A1 DE102005014334 A1 DE 102005014334A1
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mixture
wine
hypnotic
sedative
agitating
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DE102005014334B4 (en
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Franz Udo Willerscheidt
Marion Hedwig Willerscheidt
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Franz Udo Willerscheidt De
MARION HEDWIG WILLERSCHEIDT, DE
Willerscheidt Franz Udo De
Willerscheidt Marion Hedwig De
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Preparation of a hypnotic/sedative, psychopharmacologic drugs/anti depressive and an anxiolytic comprises adding myrrh tincture and wine to give a mixture, mixing sweet wood root juice with the mixture and agitating the obtained mixture. ACTIVITY : Hypnotic; Neuroprotective; Nootropic. No biological data given. MECHANISM OF ACTION : None given.

Description

technisches Gebiet: technical area:

  • mikrobiologisches Verfahren zur Herstellung eines Mittelsmicrobiological process for the preparation of an agent

a) Hypnotika/Sedativaa) Hypnotics / Sedatives

Pflanzliche Hypnotika/Sedativa zeigen nur eine Besserung zwischen 10%–30%.vegetable Hypnotics / sedatives show only an improvement between 10% -30%.

Chemisch definierte Hypnotika/Sedativa haben starke Nebenwirkungen und beeinträchtigen das Reaktionsvermögen.chemical Defined hypnotics / sedatives have strong side effects and affect the reactivity.

b) Psychopharmaka/Antidepressiva/Anxiolytikab) psychotropic drugs / antidepressants / anxiolytics

Pflanzliche Psychopharmaka/Antidepressiva zeigen nur eine Besserung zwischen 10%–20%.vegetable Psychotropic drugs / antidepressants only show an improvement between 10% -20%.

Chemisch definierte Psychopharmaka/Antidepressiva haben starke Nebenwirkungen und beeinträchtigen das Reaktionsvermögen.chemical Defined psychotropic drugs / antidepressants have strong side effects and affect the reactivity.

Beschreibung der Herstellung und WirkprinzipDescription of the production and operating principle

Zur Herstellung werden verwendet:
handelsüblicher herber Rotwein als Trägersubstanz
Tinctura Myrrhae(90% Ethanol) 1 : 5
Succus Liquiritiae depur. Solut. 1+1
For the production are used:
commercial herber red wine as a carrier
Tinctura Myrrhae (90% ethanol) 1: 5
Succus Liquiritiae depur. Solut. 1 + 1

Zu einem Liter Wein gibt man 100 ml Myrrhentinktur. Der Mix wird 15 min. leicht geschüttelt. Anschließend wird 80 ml Süßholzwurzelsaft dem Mix hinzugeführt. Die Mixtur wird nun 7 Tage lang täglich 20 min. leicht geschüttelt.
Dosierung: einmal täglich 20–25 Tropfen.
One liter of wine is added with 100 ml of myrrhine tincture. The mix is 15 min. slightly shaken. Then add 80 ml of licorice root juice to the mix. The mixture is now daily 20 minutes for 7 days. slightly shaken.
Dosage: 20-25 drops once daily.

Bedenken zur inneren Verwendung von Myrrhe und Süßholzwurzel:
Die Firma Repha empfiehlt für Ihr Medikament "Myrrhinil-intest" eine Tagesdosis von: 600mg bis 1200 mg.
Concerns about the internal use of myrrh and licorice root:
The company Repha recommends for your drug "Myrrhinil-intest" a daily dose of: 600mg to 1200 mg.

Die Tagesdosis von Myrrhe meiner Mixtur beträgt: ca. 10 mg.The Daily dose of myrrh of my mixture is about 10 mg.

Hinzu kommt, daß die Zugabe von Succus Liquiritae die Toxizität von Arzneimitteln herabsetzt.
Quellenangabe: Arzneibuch der chinesischen Medizin; Glycyrrhizae Radix; Wirkung und Indikation; Deutscher Apotheker Verlag Stuttgart
In addition, the addition of Succus Liquiritae reduces the toxicity of drugs.
Source: Pharmacopoeia of Chinese Medicine; Glycyrrhizae Radix; Effect and indication; German Pharmacist Verlag Stuttgart

Die Tagesdosis für Süßholzwurzel liegt bei ca. 25mg.The Daily dose for licorice is about 25mg.

Laut dem "Deutschen Arznei Buch" liegt die bedenkliche Tagesdosis für Glycyrrhizinsäure bei, über 100mg.Loud the "German medicine Book "lies the questionable Daily dose for glycyrrhizic at, over 100mg.

Nebenwirkungen bei Patienten mit: Lebererkrankungen; Nierenerkrankungen; oder Hypokaliämie konnte ich nicht beobachten. Bei 10% der Hypertoniker kam es, bei Einnahme vor dem Schlafengehen zu Aufregung im Gemüht.side effects in patients with: liver disease; Kidney disease; or hypokalaemia could I do not watch. In 10% of hypertensive patients, when ingested before going to bed to excitement in the harvested.

Die Einnahme der 25 Tropfen (Tagesdosis) auf ein Glas Wasser ca. 50 mL nach dem Mittagessen blieb bei allen Patienten gut verträglich und Nebenwirkungsfrei.The Take the 25 drops (daily dose) on a glass of water about 50 mL after lunch remained well tolerated in all patients and No side effects.

Wirkprinzip:Operating principle:

24% der Testpersonen beschreiben eine Aufhellung ihres Gemüts nach 20 min. bis 45 min.24% the subjects describe a lightening of their mind 20 min. up to 45 min.

58% der Testpersonen hatten in der 1 Wo. keine Einschlaf- oder Durchschlafstörungen mehr.58% the subjects had in the 1 Wo. no more falling asleep or staying asleep.

Nach zwei Wochen medikamentation liegt die Quote bei 87%.
Psyche: Ängste; Sorgen; Depressionen; Trauer; Unruhe; Neurosen
After two weeks of medication, the rate is 87%.
Psyche: fears; To care; Depressions; mourning; Unrest; neuroses

Alle Testpersonen mit psychischen Problemen hatten, nach einer 14 tägigen Einnahme, eine Linderung zwischen 30%–70%.All Subjects with mental health problems had, after a 14-day intake, a relief between 30% -70%.

Resultat in Bezugnahme auf den Stand der Technik:Result in reference on the state of the art:

Chemisch definierte Hypnotika/Sedativa und Psychopharmaka/Antidepressiva haben starke Nebenwirkungen bis zur Suchtgefahr.chemical defined hypnotics / sedatives and psychotropic drugs / antidepressants have strong side effects to addictiveness.

Pflanzliche Hypnotika/Sedativa und Psychopharmaka/Antidepressiva/Anxiolytika sind als Einzelstoffe, Kombinationen, Teezubereitungen, nicht allgemein verträglich. Teilweise schränken Sie das Reaktionsvermögen ein oder erhöhen die Photosensibilität. Quellenangabe: Rote Liste; Anwendungsbeschränkungen (H 55) Die Wirksamkeit bisheriger pflanzlicher Produkte liegt nach meiner 20 jährigen Erfahrung zwischen 10% und 30%.vegetable Hypnotics / sedatives and psychotropic drugs / antidepressants / anxiolytics are as individual substances, combinations, tea preparations, not general compatible. Partial cupboards You the reactivity on or increase the photosensitivity. Source: Red List; Application restrictions (H 55) The effectiveness previous herbal products lies after my 20 years of experience between 10% and 30%.

An Schwangeren und Kindern wurde die, unter Punkt 5. verwendeten Mixtur, nicht getestet.At Pregnant women and children became the mixture used under point 5. not tested.

Die unter Punkt 5. verwendete Mixtur ist universell einsetzbar und hat einen überzeugend hohen Wirkungsgrad als rein pflanzliches Produkt. Die Herstellungskosten für einen Liter Mixtur betragen ca. EUR 5,00.The under point 5 used mixture is universally applicable and has a convincing one high efficiency as a pure vegetable product. The manufacturing costs for one Liter mixture amount to approx. EUR 5,00.

Anmerkung:Annotation:

Die Indikationsmerkmale von Myrrhe und Süßholzwurzel werden, durch das unter Punkt 5. verwendete Verfahren, in der Mixtur unbedeutend. Ganz neue Indikationsmerkmale sind entstanden.The indications of myrrh and Licorice root becomes insignificant in the mixture by the method used under point 5. Completely new indications have emerged.

Claims (1)

Wir beantragen Patentschutz für: a) die Herstellung eines Hypnotika/Sedativa unter Verwendung von: Myrrhe und Süßholzwurzel b) die Herstellung eines Psychopharmaka/Antidepressiva unter Verwendung von: Myrrhe und Süßholzwurzel c) die Herstellung eines Anxiolytika unter Verwendung von Myrrhe und Süßholzwurzel d) Das Herstellungsverfahren wie unter Punkt 5. angegeben mit Wein, Myrrhe und Süßholzwurzel. e) Die Herstellung wie unter Punkt 5. angegeben als Trockenextrakt Produkt aus Wein, Myrrhe und Süßholzwurzel.We apply for patent protection for: a) the production of a hypnotics / sedatives using: myrrh and licorice root b) the preparation of a psychotropic / antidepressant using from: myrrh and licorice root c) the preparation of an anxiolytics using myrrh and licorice d) The production process as indicated in point 5 with wine, Myrrh and licorice root. e) The preparation as indicated under point 5 as a dry extract Product of wine, myrrh and licorice root.
DE102005014334A 2005-03-24 2005-03-24 Sedative comprising myrrh, licorice root and wine Expired - Fee Related DE102005014334B4 (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997002040A1 (en) * 1995-07-03 1997-01-23 Bevilacqua, Maria Terpene-based pharmaceutical product
US20020031559A1 (en) * 2000-03-08 2002-03-14 Liang Kin C. Herbal suppositories
US20040180104A1 (en) * 2003-03-11 2004-09-16 Lin Chih Hui Herbal composition for preventing and/or treating conditions in associated with depression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002058450A (en) * 2000-08-17 2002-02-26 (有)日本バイオメディカル研究所 Food product for antidepression

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997002040A1 (en) * 1995-07-03 1997-01-23 Bevilacqua, Maria Terpene-based pharmaceutical product
US20020031559A1 (en) * 2000-03-08 2002-03-14 Liang Kin C. Herbal suppositories
US20040180104A1 (en) * 2003-03-11 2004-09-16 Lin Chih Hui Herbal composition for preventing and/or treating conditions in associated with depression

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JP 2002-058450 A (abstracts). In: Patent Abstracts of Japan (CD-ROM)
JP 2002058450 A (abstracts). In: Patent Abstractsof Japan (CD-ROM) *
Psychrembel Wörterbuch Naturheilkunde und alterna- tive Heilkunde, 1998, S. 274, ISBN: 3-8112-1663-5
Psychrembel Wörterbuch Naturheilkunde und alterna-tive Heilkunde, 1998, S. 274, ISBN: 3-8112-1663-5 *

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