DE1003920B - Disinfectants - Google Patents

Disinfectants

Info

Publication number
DE1003920B
DE1003920B DEC7926A DEC0007926A DE1003920B DE 1003920 B DE1003920 B DE 1003920B DE C7926 A DEC7926 A DE C7926A DE C0007926 A DEC0007926 A DE C0007926A DE 1003920 B DE1003920 B DE 1003920B
Authority
DE
Germany
Prior art keywords
formula
benzyl
disinfectants
compounds
disinfection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEC7926A
Other languages
German (de)
Inventor
Dr Jules Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
BASF Schweiz AG
Original Assignee
Ciba Geigy AG
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Ciba AG filed Critical Ciba Geigy AG
Publication of DE1003920B publication Critical patent/DE1003920B/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/38—Cationic compounds
    • C11D1/62—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Description

DEUTSCHESGERMAN

Die Erfindung betrifft Desinfektionsmittel, enthaltend wasserlösliche quaternäre Ammoniumsalze der FormelThe invention relates to disinfectants containing water-soluble quaternary ammonium salts of the formula

CH,CH,

XH2CH2OH
XH9CH9OHXH 2 CH 2 OH
XH 9 CH 9 OH

X"X "

Anmelder: CIBA Aktiengesellschaft, Basel (Schweiz)Applicant: CIBA Aktiengesellschaft, Basel (Switzerland)

Vertreter: Dipl.-Ing. E. Splanemann, Patentanwalt, Hamburg 36, Neuer Wall 10Representative: Dipl.-Ing. E. Splanemann, patent attorney, Hamburg 36, Neuer Wall 10

Beanspruchte Priorität: Schweiz vom 29. Juli 1952Claimed priority: Switzerland of July 29, 1952

Dr. Jules Meyer, Basel (Schweiz), ist als Erfinder genannt wordenDr. Jules Meyer, Basel (Switzerland), has been named as the inventor

worin X ein Anion bedeutet. 1O wherein X is an anion. 1 O

Die Verbindungen der erwähnten Formel werden zweckmäßig ausDodecyl-di-(/?-hydroxyäthyl)-amin durch Einwirkung von benzylierenden Mitteln der FormelThe compounds of the formula mentioned are expediently made from dodecyl di - (/? - hydroxyethyl) amine Exposure to benzylating agents of the formula

/ N-CH2X ao 2/ N-CH 2 X ao 2

das Benzylnitrat und insbesondere die Benzylhalogenide,the benzyl nitrate and especially the benzyl halides,

hergestellt. Sie können auch durch Umsetzung von wie Benzylbromid oder Benzylchlorid, zu verstehen. Benzyl-di-(/S-hydroxyäthyl)-amin mit einem Dodecyl- Wird zur Herstellung für die erfindungsgemäßen Pro-manufactured. They can also be understood by reacting such as benzyl bromide or benzyl chloride. Benzyl di - (/ S-hydroxyethyl) amine with a dodecyl is used for the preparation of the inventive pro

halogenid erhalten werden. 25 dukte Dodecyl-di-(/3-oxyäthyl)-amin und Benzylchloridhalide can be obtained. 25 products dodecyl-di- (/ 3-oxyethyl) -amine and benzyl chloride

Die erfindungsgemäßen Verbindungen können schließ- benutzt, so gelangt man zu dem als Baktericid und lieh auch aus tertiären Aminen der allgemeinen Formel Fungicid sehr wirksamen Benzyl-dodecyl-di-(/?-oxyäthyl)-The compounds according to the invention can finally be used as a bactericide and borrowed from tertiary amines of the general formula Fungicid very effective benzyl-dodecyl-di - (/? - oxyäthyl) -

ammoniumchlorid der Formel
CH2CH2OHammonium chloride of the formula
CH 2 CH 2 OH

II.

-N-N

C12H25 C 12 H 25

und einer Verbindung der Formel XCH2CH2OH hergestellt werden.and a compound of the formula XCH 2 CH 2 OH.

Ein besonders geeignetes Ausgangsmaterial ist das Dodecyl-di-(/?~oxyäthyl)-amin der FormelA particularly suitable starting material is dodecyldi (/? ~ Oxyethyl) amine of the formula

XH2CH2OHXH 2 CH 2 OH

CHoCHo

CH9CH9OHCH 9 CH 9 OH

erhe

■N.■ N.

XH9CH9OHXH 9 CH 9 OH

CH9CH0OHCH 9 CH 0 OH

das z. B. durch Anlagerung von 2 Mol Äthylenoxyd an 1 Mol Dodecylamin oder durch Umsetzung von Dodecylbromid mit Diäthanolamin erhältlich ist.
Unter den benzylierenden Mitteln der Formelthe Z. B. can be obtained by adding 2 moles of ethylene oxide to 1 mole of dodecylamine or by reacting dodecyl bromide with diethanolamine.
Among the benzylating agents of the formula

• CH9 · X• CH 9 · X

sind die Benzylester von anorganischen Säuren, z. B.are the benzyl esters of inorganic acids, e.g. B.

Die Umsetzungen, die zu den erfindungsgemäßen quaternären Salzen führen, werden unter den für die Herstellung von ähnlichen Verbindungen bekannten Maßnahmen und Bedingungen durchgeführt. Für die Herstellungsverfahren wird hiermit Patentschutz nichtThe reactions that lead to the quaternary salts according to the invention are among those for Preparation of similar compounds carried out known measures and conditions. For the This does not mean that the manufacturing process is patented

beansprucht. :claimed. :

Die neuen quaternären Salze sind in Wasser und auch in verschiedenen organischen Lösungsmitteln löslich. Solche Lösungen, namentlich die wäßrigen, zeigen noch in großer Verdünnung starke baktericide und fungicide Eigenschaften. Da die Verbindungen außerdem geruchlos und für den Menschen verhältnismäßig ungiftig sind, sind sie ganz allgemein verwendbare Desinfektions- und Konservierungsmittel. Sie sind z. B. geeignet zur Desinfektion von Eß-, Trink- und Vorratsgeräten, z. B. inThe new quaternary salts are soluble in water and also in various organic solvents. Such solutions, especially the aqueous ones, show strong bactericides and fungicides even in great dilution Properties. Since the compounds are also odorless and relatively non-toxic to humans, they are generally usable disinfectants and preservatives. You are e.g. B. suitable for disinfection of eating, drinking and storage devices, e.g. Am

1 609 838/3241 609 838/324

der Getränkeindustrie. Ihre Verwendung ist ferner angezeigt zur Desinfektion von ärztlichen Instrumenten, Verbandstoffen und anderen Gebrauchsgegenständen sowie von Wäsche u. dgl. Auch die Desinfektion von Fußböden und Wänden kann auf diese Weise erfolgen. Die neuen Verbindungen lassen sich auch zur Desinfektion bzw. Konservierung von Nahrungsmitteln, wie Obst, Gemüse u. dgl., verwenden. Auch zur Konservierung, d. h. Ausschaltung von bakteriellen und autolytischen Zersetzungsvorgängen von tierischem Material, wie ζ. Β. ίο Fleisch, Häuten, Blut, Drüsen oder sonstigen Organen od. dgl., sind diese Verbindungen geeignet.the beverage industry. Their use is also indicated for the disinfection of medical instruments, Dressing materials and other utensils as well as laundry and the like. Also the disinfection of Floors and walls can be done this way. The new compounds can also be used for disinfection or preservation of foods such as fruits, vegetables and the like. Also for preservation, d. H. Elimination of bacterial and autolytic decomposition processes of animal material, such as ζ. Β. ίο Meat, skins, blood, glands or other organs or the like, these compounds are suitable.

Die neuen Substanzen lassen sich auch in Verdünnung mit hartem Wasser verwenden, ohne an ihrer Wirkung einzubüßen. In den zur Desinfektion notwendigen Verdünnungen greifen sie die Haut nicht an und können deshalb auch zur Desinfektion der Haut, insbesondere der Hände, Verwendung finden. Sie können für sich allein zur Anwendung gelangen oder zusammen mit anderen aktiven Verbindungen. Zweckmäßig werden sie zu den für Desinfektionsmittel üblichen Handelsformen, z. B. Lösungen, Cremen oder Streupudern verarbeitet. Im allgemeinen genügt eine geringe Menge der erfindungsgemäßen Verbindungen, um die gewünschte Konservierung zu erhalten.The new substances can also be used in dilution with hard water without affecting their effect to forfeit. In the dilutions required for disinfection, they do not and can not attack the skin therefore also find use for disinfecting the skin, especially the hands. You can for yourself can be used alone or together with other active compounds. Become useful they to the usual commercial forms for disinfectants, z. B. solutions, creams or sprinkling powders processed. In general, a small amount of the compounds according to the invention is sufficient to achieve the desired Preservation.

Claims (1)

PATENTANSPRUCH:PATENT CLAIM: Desinfektionsmittel, enthaltend wasserlösliche quaternäre Ammoniumsalze der FormelDisinfectants containing water-soluble quaternary ammonium salts of the formula CH2CH2OHCH 2 CH 2 OH C12H25-NC 12 H 25 -N CH9 CH 9 CH2CH2OHCH 2 CH 2 OH worin X ein Anion bedeutet.wherein X is an anion. In Betracht gezogene Druckschriften: Deutsche Patentschriften Nr. 680 599, 708 076; USA.-Patentschriften Nr. 2 541 088, 2 541 089; Chemiker-Zeitung, 62, 404, 1938.Considered publications: German Patent Nos. 680 599, 708 076; U.S. Patent Nos. 2,541,088, 2,541,089; Chemiker-Zeitung, 62, 404, 1938. © 609 838/324 2.57© 609 838/324 2.57
DEC7926A 1952-07-29 1953-07-22 Disinfectants Pending DE1003920B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1003920X 1952-07-29

Publications (1)

Publication Number Publication Date
DE1003920B true DE1003920B (en) 1957-03-07

Family

ID=4552178

Family Applications (1)

Application Number Title Priority Date Filing Date
DEC7926A Pending DE1003920B (en) 1952-07-29 1953-07-22 Disinfectants

Country Status (1)

Country Link
DE (1) DE1003920B (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE680599C (en) * 1933-04-13 1939-09-01 Gerhard Domagk Dr Procedure for disinfection and preservation
DE708076C (en) * 1935-05-25 1941-07-11 Gerhard Domagk Dr Disinfection method
US2541088A (en) * 1946-12-05 1951-02-13 Burton T Bush Inc Process for preparing n-alkyl substituted n, n-beta, beta'-dialkanolamines
US2541089A (en) * 1946-12-05 1951-02-13 Burton T Bush Inc Process for preparing n-alkyl-substituted n-beta alkanolamines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE680599C (en) * 1933-04-13 1939-09-01 Gerhard Domagk Dr Procedure for disinfection and preservation
DE708076C (en) * 1935-05-25 1941-07-11 Gerhard Domagk Dr Disinfection method
US2541088A (en) * 1946-12-05 1951-02-13 Burton T Bush Inc Process for preparing n-alkyl substituted n, n-beta, beta'-dialkanolamines
US2541089A (en) * 1946-12-05 1951-02-13 Burton T Bush Inc Process for preparing n-alkyl-substituted n-beta alkanolamines

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