DE07011327T1 - Schnell gepulste Phakoemulsifikationsleistungszuführung für verbrennungsfreie Chirurgie - Google Patents
Schnell gepulste Phakoemulsifikationsleistungszuführung für verbrennungsfreie Chirurgie Download PDFInfo
- Publication number
- DE07011327T1 DE07011327T1 DE07011327T DE07011327T DE07011327T1 DE 07011327 T1 DE07011327 T1 DE 07011327T1 DE 07011327 T DE07011327 T DE 07011327T DE 07011327 T DE07011327 T DE 07011327T DE 07011327 T1 DE07011327 T1 DE 07011327T1
- Authority
- DE
- Germany
- Prior art keywords
- needle
- load
- handpiece
- drive voltage
- phacoemulsification
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001356 surgical procedure Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
- A61F9/00745—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/0207—Driving circuits
- B06B1/0223—Driving circuits for generating signals continuous in time
- B06B1/0238—Driving circuits for generating signals continuous in time of a single frequency, e.g. a sine-wave
- B06B1/0246—Driving circuits for generating signals continuous in time of a single frequency, e.g. a sine-wave with a feedback signal
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/0207—Driving circuits
- B06B1/0223—Driving circuits for generating signals continuous in time
- B06B1/0238—Driving circuits for generating signals continuous in time of a single frequency, e.g. a sine-wave
- B06B1/0246—Driving circuits for generating signals continuous in time of a single frequency, e.g. a sine-wave with a feedback signal
- B06B1/0253—Driving circuits for generating signals continuous in time of a single frequency, e.g. a sine-wave with a feedback signal taken directly from the generator circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00026—Conductivity or impedance, e.g. of tissue
- A61B2017/0003—Conductivity or impedance, e.g. of tissue of parts of the instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00106—Sensing or detecting at the treatment site ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00154—Details of operation mode pulsed
- A61B2017/00194—Means for setting or varying the repetition rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/32007—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic with suction or vacuum means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00666—Sensing and controlling the application of energy using a threshold value
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B2201/00—Indexing scheme associated with B06B1/0207 for details covered by B06B1/0207 but not provided for in any of its subgroups
- B06B2201/50—Application to a particular transducer type
- B06B2201/55—Piezoelectric transducer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B2201/00—Indexing scheme associated with B06B1/0207 for details covered by B06B1/0207 but not provided for in any of its subgroups
- B06B2201/70—Specific application
- B06B2201/76—Medical, dental
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Surgery (AREA)
- Mechanical Engineering (AREA)
- Surgical Instruments (AREA)
- Electrotherapy Devices (AREA)
- Paper (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Physical Water Treatments (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Abstract
Phakoemulsifikationssystem umfassend:
ein Phakoemulsifikationshandstück mit einer Nadel, welche an der distalen Spitze eine Last aufweist;
eine Energiequelle zum Bereitstellen elektrischer Leistung, welche eine Antriebsspannung für das Handstück aufweist, um die Nadel ultraschallförmig zu vibrieren;
eine Steuereinheit, welche es ermöglicht, dem Handstück elektrische Leitung in Pulsen bereitzustellen, welche einen Pulsarbeitszyklus und eine Pulswiederholungsrate von zwischen ungefähr 25 und ungefähr 2000 Pulsen pro Sekunde aufweist und welche die Antriebsspannung der elektrischen Leistung in Antwort auf eine Veränderung der Last der Nadel anpasst.
ein Phakoemulsifikationshandstück mit einer Nadel, welche an der distalen Spitze eine Last aufweist;
eine Energiequelle zum Bereitstellen elektrischer Leistung, welche eine Antriebsspannung für das Handstück aufweist, um die Nadel ultraschallförmig zu vibrieren;
eine Steuereinheit, welche es ermöglicht, dem Handstück elektrische Leitung in Pulsen bereitzustellen, welche einen Pulsarbeitszyklus und eine Pulswiederholungsrate von zwischen ungefähr 25 und ungefähr 2000 Pulsen pro Sekunde aufweist und welche die Antriebsspannung der elektrischen Leistung in Antwort auf eine Veränderung der Last der Nadel anpasst.
Claims (3)
- Phakoemulsifikationssystem umfassend: ein Phakoemulsifikationshandstück mit einer Nadel, welche an der distalen Spitze eine Last aufweist; eine Energiequelle zum Bereitstellen elektrischer Leistung, welche eine Antriebsspannung für das Handstück aufweist, um die Nadel ultraschallförmig zu vibrieren; eine Steuereinheit, welche es ermöglicht, dem Handstück elektrische Leitung in Pulsen bereitzustellen, welche einen Pulsarbeitszyklus und eine Pulswiederholungsrate von zwischen ungefähr 25 und ungefähr 2000 Pulsen pro Sekunde aufweist und welche die Antriebsspannung der elektrischen Leistung in Antwort auf eine Veränderung der Last der Nadel anpasst.
- Phakoemulsifikationssystem gemäß Anspruch 1, wobei die Steuereinheit so konfiguriert ist, dass sie die Antriebsspannung in Antwort auf ein Ansteigen der Last der Nadel erhöht, und die Antriebsspannung in Antwort auf ein Abnehmen der Last der Nadel absenkt.
- Phakoemulsifikationssystem gemäß Anspruch 1, wobei die Steuereinheit es ermöglicht, dass der Pulsarbeitszyklus variiert werden kann.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US764814 | 2001-01-16 | ||
US09/764,814 US6629948B2 (en) | 1997-01-22 | 2001-01-16 | Rapid pulse phaco power for burn free surgery |
Publications (1)
Publication Number | Publication Date |
---|---|
DE07011327T1 true DE07011327T1 (de) | 2008-02-21 |
Family
ID=25071862
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60221791T Expired - Lifetime DE60221791T2 (de) | 2001-01-16 | 2002-01-09 | Schnell gepulste phakoemulsifikationsleistungszuführung für verbrennungsfreie chirurgie |
DE07011327T Pending DE07011327T1 (de) | 2001-01-16 | 2002-01-09 | Schnell gepulste Phakoemulsifikationsleistungszuführung für verbrennungsfreie Chirurgie |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60221791T Expired - Lifetime DE60221791T2 (de) | 2001-01-16 | 2002-01-09 | Schnell gepulste phakoemulsifikationsleistungszuführung für verbrennungsfreie chirurgie |
Country Status (8)
Country | Link |
---|---|
US (1) | US6629948B2 (de) |
EP (2) | EP1351631B1 (de) |
JP (1) | JP4202758B2 (de) |
AT (1) | ATE369824T1 (de) |
BR (1) | BR0206480B1 (de) |
CA (1) | CA2434480C (de) |
DE (2) | DE60221791T2 (de) |
WO (1) | WO2002056806A1 (de) |
Families Citing this family (56)
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US7169123B2 (en) * | 1997-01-22 | 2007-01-30 | Advanced Medical Optics, Inc. | Control of pulse duty cycle based upon footswitch displacement |
US6780165B2 (en) * | 1997-01-22 | 2004-08-24 | Advanced Medical Optics | Micro-burst ultrasonic power delivery |
US20040097996A1 (en) | 1999-10-05 | 2004-05-20 | Omnisonics Medical Technologies, Inc. | Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode |
WO2002013906A1 (en) * | 2000-08-16 | 2002-02-21 | Vanderbilt University | Methods and devices for optical stimulation of neural tissues |
US7182759B2 (en) * | 2001-09-07 | 2007-02-27 | Advanced Medical Optics, Inc. | Cataract extraction apparatus and method with rapid pulse phaco power |
US6733491B2 (en) * | 2001-09-07 | 2004-05-11 | Advanced Medical Optics | Cataract extraction apparatus and method |
US6997935B2 (en) * | 2001-11-20 | 2006-02-14 | Advanced Medical Optics, Inc. | Resonant converter tuning for maintaining substantially constant phaco handpiece power under increased load |
US7316664B2 (en) * | 2002-10-21 | 2008-01-08 | Advanced Medical Optics, Inc. | Modulated pulsed ultrasonic power delivery system and method |
US7077820B1 (en) | 2002-10-21 | 2006-07-18 | Advanced Medical Optics, Inc. | Enhanced microburst ultrasonic power delivery system and method |
US20040092921A1 (en) * | 2002-10-21 | 2004-05-13 | Kadziauskas Kenneth E. | System and method for pulsed ultrasonic power delivery employing cavitation effects |
US20040152990A1 (en) * | 2003-01-29 | 2004-08-05 | Mackool Richard J. | Monitoring thermal conditions to vary operation of an ultrasonic needle tip of a surgical instrument |
US20130178789A1 (en) * | 2003-01-29 | 2013-07-11 | Novartis Ag | Monitoring Thermal Conditions To Vary Operation of an Ultrasonic Needle Tip of a Surgical Instrument |
EP2604235A1 (de) | 2003-03-12 | 2013-06-19 | Abbott Medical Optics Inc. | System und Verfahren zur Bereitstellung gepulster Ultraschallenergie durch Anwendung von Kavitationseffekten |
US7794414B2 (en) | 2004-02-09 | 2010-09-14 | Emigrant Bank, N.A. | Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes |
US7572242B2 (en) * | 2004-03-22 | 2009-08-11 | Alcon, Inc. | Method of operating an ultrasound handpiece |
US7645255B2 (en) * | 2004-03-22 | 2010-01-12 | Alcon, Inc. | Method of controlling a surgical system based on irrigation flow |
US7625388B2 (en) * | 2004-03-22 | 2009-12-01 | Alcon, Inc. | Method of controlling a surgical system based on a load on the cutting tip of a handpiece |
US7645256B2 (en) * | 2004-08-12 | 2010-01-12 | Alcon, Inc. | Ultrasound handpiece |
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US7297137B2 (en) * | 2004-03-22 | 2007-11-20 | Alcon, Inc. | Method of detecting surgical events |
US7811255B2 (en) * | 2004-03-22 | 2010-10-12 | Alcon, Inc. | Method of controlling a surgical system based on a rate of change of an operating parameter |
US9119700B2 (en) | 2004-11-30 | 2015-09-01 | Novartis Ag | Graphical user interface system and method for representing and controlling surgical parameters |
US7945341B2 (en) | 2004-11-30 | 2011-05-17 | Alcon, Inc. | Graphical user interface for selecting pulse parameters in a phacoemulsification surgical system |
AU2005323538A1 (en) * | 2005-01-05 | 2006-07-13 | Advanced Medical Optics, Inc. | Phacoemulsification system utilizing graphical user interfaces for adjusting pulse parameters |
US20060149301A1 (en) * | 2005-01-05 | 2006-07-06 | Claus Michael J | Phacoemulsification system utilizing graphical user interfaces for adjusting pulse parameters |
US8241242B2 (en) * | 2005-03-30 | 2012-08-14 | Abbott Medical Optics Inc. | Phacoaspiration flow restrictor with bypass tube |
US20060253062A1 (en) * | 2005-04-26 | 2006-11-09 | Alcon, Inc. | Low resistance irrigation system and apparatus |
US8353297B2 (en) * | 2005-08-31 | 2013-01-15 | Novartis Ag | Pulse manipulation for controlling a phacoemulsification surgical system |
DE102005053918A1 (de) * | 2005-11-11 | 2007-05-16 | Zimmer Elektromedizin Gmbh | Verfahren und Vorrichtung zur Einstrahlung von Ultraschall in Gewebe |
US7785336B2 (en) * | 2006-08-01 | 2010-08-31 | Abbott Medical Optics Inc. | Vacuum sense control for phaco pulse shaping |
CA2662869A1 (en) | 2006-09-07 | 2008-03-13 | Advanced Medical Optics, Inc. | Systems and methods for historical display of surgical operating parameters |
US8982195B2 (en) | 2006-09-07 | 2015-03-17 | Abbott Medical Optics Inc. | Digital video capture system and method with customizable graphical overlay |
US20080172076A1 (en) * | 2006-11-01 | 2008-07-17 | Alcon, Inc. | Ultrasound apparatus and method of use |
US7981074B2 (en) * | 2006-11-02 | 2011-07-19 | Novartis Ag | Irrigation/aspiration system |
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US20080139994A1 (en) * | 2006-12-08 | 2008-06-12 | Alcon, Inc. | Torsional Ultrasound at Resonant Frequencies That Eliminate Chatter |
US8579929B2 (en) * | 2006-12-08 | 2013-11-12 | Alcon Research, Ltd. | Torsional ultrasound hand piece that eliminates chatter |
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ITVI20070159A1 (it) * | 2007-05-31 | 2008-12-01 | Maurizio Marzaro | Metodo di preparazione alla rivitalizzazione di un tessuto organico a-cellulare e dispositivo atto a realizzare tale metodo |
US20100036256A1 (en) * | 2008-08-08 | 2010-02-11 | Mikhail Boukhny | Offset ultrasonic hand piece |
US8631831B2 (en) | 2008-09-04 | 2014-01-21 | Alcon Research, Ltd. | Multi-compliant tubing |
US9149387B2 (en) * | 2008-09-04 | 2015-10-06 | Novartis Ag | Varying material properties of a single fluidic line in ophthalmology tubing |
US20100094321A1 (en) * | 2008-10-10 | 2010-04-15 | Takayuki Akahoshi | Ultrasound Handpiece |
DE102009015911A1 (de) * | 2009-04-03 | 2010-10-07 | Carl Zeiss Meditec Ag | Vorrichtung und Verfahren zur Entfernung eines Lentikels aus der Hornhaut |
US8623040B2 (en) | 2009-07-01 | 2014-01-07 | Alcon Research, Ltd. | Phacoemulsification hook tip |
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US20110311943A1 (en) * | 2010-06-21 | 2011-12-22 | Steven Gagliano | Power varying pedal |
US11547539B2 (en) | 2010-06-21 | 2023-01-10 | Steven Gagliano | Power varying pedal |
US8784357B2 (en) | 2010-09-15 | 2014-07-22 | Alcon Research, Ltd. | Phacoemulsification hand piece with two independent transducers |
US10258505B2 (en) | 2010-09-17 | 2019-04-16 | Alcon Research, Ltd. | Balanced phacoemulsification tip |
JP5696484B2 (ja) * | 2011-01-12 | 2015-04-08 | セイコーエプソン株式会社 | 流体噴射装置、医療機器 |
US8414605B2 (en) | 2011-07-08 | 2013-04-09 | Alcon Research, Ltd. | Vacuum level control of power for phacoemulsification hand piece |
US9050627B2 (en) | 2011-09-02 | 2015-06-09 | Abbott Medical Optics Inc. | Systems and methods for ultrasonic power measurement and control of phacoemulsification systems |
US10092741B2 (en) * | 2015-06-08 | 2018-10-09 | Misonix, Inc. | Ultrasonic surgical apparatus and associated method |
US20170172796A1 (en) * | 2015-12-16 | 2017-06-22 | Novartis Ag | Surgical system with substance delivery system |
US11877953B2 (en) | 2019-12-26 | 2024-01-23 | Johnson & Johnson Surgical Vision, Inc. | Phacoemulsification apparatus |
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-
2001
- 2001-01-16 US US09/764,814 patent/US6629948B2/en not_active Expired - Lifetime
-
2002
- 2002-01-09 AT AT02704080T patent/ATE369824T1/de not_active IP Right Cessation
- 2002-01-09 WO PCT/US2002/000471 patent/WO2002056806A1/en active IP Right Grant
- 2002-01-09 BR BRPI0206480-4A patent/BR0206480B1/pt not_active IP Right Cessation
- 2002-01-09 DE DE60221791T patent/DE60221791T2/de not_active Expired - Lifetime
- 2002-01-09 DE DE07011327T patent/DE07011327T1/de active Pending
- 2002-01-09 EP EP02704080A patent/EP1351631B1/de not_active Expired - Lifetime
- 2002-01-09 JP JP2002557317A patent/JP4202758B2/ja not_active Expired - Fee Related
- 2002-01-09 CA CA002434480A patent/CA2434480C/en not_active Expired - Fee Related
- 2002-01-09 EP EP07011327.9A patent/EP1834614B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2434480C (en) | 2009-12-22 |
US6629948B2 (en) | 2003-10-07 |
BR0206480A (pt) | 2004-03-23 |
JP4202758B2 (ja) | 2008-12-24 |
JP2004522503A (ja) | 2004-07-29 |
CA2434480A1 (en) | 2002-07-25 |
BR0206480B1 (pt) | 2012-08-07 |
EP1351631B1 (de) | 2007-08-15 |
WO2002056806A1 (en) | 2002-07-25 |
EP1834614B1 (de) | 2015-12-30 |
EP1834614A1 (de) | 2007-09-19 |
EP1351631A1 (de) | 2003-10-15 |
ATE369824T1 (de) | 2007-09-15 |
US20010003155A1 (en) | 2001-06-07 |
DE60221791D1 (de) | 2007-09-27 |
DE60221791T2 (de) | 2008-06-05 |
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