DD129552A5 - Verfahren zur herstellung von derivaten der 3-chinolinkarbonsaeure - Google Patents

Verfahren zur herstellung von derivaten der 3-chinolinkarbonsaeure

Info

Publication number
DD129552A5
DD129552A5 DD7700197299A DD19729977A DD129552A5 DD 129552 A5 DD129552 A5 DD 129552A5 DD 7700197299 A DD7700197299 A DD 7700197299A DD 19729977 A DD19729977 A DD 19729977A DD 129552 A5 DD129552 A5 DD 129552A5
Authority
DD
German Democratic Republic
Prior art keywords
chinoline
derivatives
preparation
carboxylic acid
carboxylic
Prior art date
Application number
DD7700197299A
Other languages
German (de)
English (en)
Inventor
Andre Allais
Francois Clemence
Roger Deraedt
Martret Odile Le
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DD129552A5 publication Critical patent/DD129552A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DD7700197299A 1976-02-11 1977-02-09 Verfahren zur herstellung von derivaten der 3-chinolinkarbonsaeure DD129552A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7603754A FR2340735A1 (fr) 1976-02-11 1976-02-11 Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Publications (1)

Publication Number Publication Date
DD129552A5 true DD129552A5 (de) 1978-01-25

Family

ID=9168994

Family Applications (1)

Application Number Title Priority Date Filing Date
DD7700197299A DD129552A5 (de) 1976-02-11 1977-02-09 Verfahren zur herstellung von derivaten der 3-chinolinkarbonsaeure

Country Status (19)

Country Link
US (1) US4107310A (US06272168-20010807-M00014.png)
JP (1) JPS52116479A (US06272168-20010807-M00014.png)
AU (1) AU508345B2 (US06272168-20010807-M00014.png)
BE (1) BE851306A (US06272168-20010807-M00014.png)
CA (1) CA1089464A (US06272168-20010807-M00014.png)
CH (1) CH620437A5 (US06272168-20010807-M00014.png)
DD (1) DD129552A5 (US06272168-20010807-M00014.png)
DE (1) DE2705446A1 (US06272168-20010807-M00014.png)
DK (1) DK150512C (US06272168-20010807-M00014.png)
ES (1) ES455804A1 (US06272168-20010807-M00014.png)
FR (1) FR2340735A1 (US06272168-20010807-M00014.png)
GB (1) GB1572482A (US06272168-20010807-M00014.png)
IE (1) IE44879B1 (US06272168-20010807-M00014.png)
IL (1) IL51413A (US06272168-20010807-M00014.png)
LU (1) LU76742A1 (US06272168-20010807-M00014.png)
NL (1) NL7701398A (US06272168-20010807-M00014.png)
SE (1) SE441528B (US06272168-20010807-M00014.png)
SU (1) SU867299A3 (US06272168-20010807-M00014.png)
ZA (1) ZA77787B (US06272168-20010807-M00014.png)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190659A (en) * 1973-08-27 1980-02-26 Sandoz, Inc. Pharmaceutical preparation and use of 4-hydroxy-2-quinolinone-3-carboxylic acid esters
US4273930A (en) * 1977-06-20 1981-06-16 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acid esters
US4281131A (en) 1977-06-20 1981-07-28 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4187309A (en) * 1977-06-20 1980-02-05 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4221797A (en) * 1978-08-14 1980-09-09 Sandoz, Inc. Dihydroquinoline-one derivatives
FR2443467A1 (fr) * 1978-12-08 1980-07-04 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
FR2482596A1 (fr) * 1980-05-19 1981-11-20 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament
US4266050A (en) * 1980-07-02 1981-05-05 American Home Products Corporation 1,2-Dihydro-4-hydroxy-2-imino-N-substituted-3-quinolinecarboxamide derivatives
IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
HU190796B (en) * 1981-06-12 1986-11-28 Roussel Uclaf,Fr Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
FR2507602A1 (fr) * 1981-06-12 1982-12-17 Roussel Uclaf Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2523130A1 (fr) * 1982-03-15 1983-09-16 Roussel Uclaf Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2509728A1 (fr) * 1981-07-17 1983-01-21 Roussel Uclaf Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2537139B2 (fr) * 1982-03-15 1985-09-20 Roussel Uclaf Nouveau derive de la n-dihydrothiazolyl 3-quinoleine carboxamide, procede de preparation, application a titre de medicament et compositions le renfermant
FR2551437B2 (fr) * 1982-06-03 1985-10-25 Roussel Uclaf Nouveaux derives de l'acide 4-oh 3-quinoleine carboxylique substitues en 2, nouveau procede de preparation, leur application comme medicament et les compositions les renfermant et produits necessaires a leur preparation
FR2530633A1 (fr) * 1982-06-03 1984-01-27 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, et les compositions les renfermant
FR2532939A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur preparation, leur application comme medicament, les compositions les renfermant et les nouveaux intermediaires obtenus
FR2537140B1 (fr) * 1982-12-07 1986-07-18 Roussel Uclaf Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant
SE452170B (sv) * 1983-10-03 1987-11-16 Boliden Ab Forfarande for utvinning av metall ur koppar och/eller edelmetall innehallande material som innehaller antimon och vismut
FR2566405B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus
US4602014A (en) * 1984-07-09 1986-07-22 Ciba-Geigy Corporation Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators
JPH0358559A (ja) * 1989-07-26 1991-03-13 Sekisui Chem Co Ltd 電話システム
JPH07110853B2 (ja) * 1990-09-07 1995-11-29 シェリング・コーポレーション 抗ウイルス化合物および抗高血圧化合物
US5175151A (en) * 1990-09-07 1992-12-29 Schering Corporation Antiviral compounds and antihypertensive compounds
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
DE4138820A1 (de) * 1991-11-26 1993-05-27 Basf Ag Chinolin-3-carbonsaeureamide, deren herstellung und verwendung
SE9201076L (sv) * 1992-04-06 1993-10-07 Shimon Slavin Användningen av gamla läkemedel för behandling av diabetes
SE9400809D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of quinoline-3-carboxamide compounds
SE9400810D0 (sv) * 1994-03-10 1994-03-10 Pharmacia Ab New use of Quinoline-3-carboxamide compounds
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
SE0400235D0 (sv) * 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
US8314124B2 (en) 2004-02-06 2012-11-20 Active Biotech Ab Crystalline salts of quinoline compounds and methods for preparing them
EP2522659A3 (en) * 2004-06-24 2013-11-27 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
US8354427B2 (en) * 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
RU2556984C2 (ru) * 2004-06-24 2015-07-20 Вертекс Фармасьютикалз Инкорпорейтед Модуляторы транспортеров атф-связывающей кассеты
WO2006087830A1 (ja) * 2005-02-18 2006-08-24 Kanebo, Ltd. 帯状織物構造体およびその製法
CN101291911B (zh) * 2005-10-19 2014-08-13 泰华制药工业有限公司 拉奎尼莫钠晶体及其制备方法
EP1979367A2 (en) * 2005-12-24 2008-10-15 Vertex Pharmaceuticals Incorporated Quinolin-4-one derivatives as modulators of abc transporters
LT1993360T (lt) 2005-12-28 2017-06-12 Vertex Pharmaceuticals Incorporated N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma
MX2008015808A (es) * 2006-06-12 2009-02-17 Teva Pharma Preparaciones de laquinimod estable.
US20080221161A1 (en) * 2007-02-09 2008-09-11 Kalypsys, Inc. Heterocyclic modulators of tgr5 for treatment of disease
EP2977049A1 (en) 2007-12-20 2016-01-27 Teva Pharmaceutical Industries, Ltd. Stable laquinimod preparations
JP2012502038A (ja) * 2008-09-03 2012-01-26 テバ ファーマシューティカル インダストリーズ リミティド 免疫機能の２−オキソ−１，２−ジヒドロ−キノリンモジュレーター
PT3330255T (pt) 2009-03-20 2021-01-13 Vertex Pharma Processo para a fabricação de modeladores do regulador da condutância transmembranar da fibrose quística
US8598203B2 (en) * 2009-07-30 2013-12-03 Teva Pharmaceutical Industries, Ltd. Treatment of Crohn's disease with laquinimod
PL2467372T3 (pl) * 2009-08-10 2017-04-28 Teva Pharmaceutical Industries Ltd. Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu
ES2601819T3 (es) * 2010-03-03 2017-02-16 Teva Pharmaceutical Industries Ltd. Tratamiento de la artritis lúpica usando laquinimod
US8501766B2 (en) * 2010-03-03 2013-08-06 Teva Pharmaceutical Industries Ltd. Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
ES2558556T3 (es) * 2010-03-03 2016-02-05 Teva Pharmaceutical Industries Ltd. Tratamiento de nefritis lúpica usando laquinimod
CN102267984B (zh) * 2010-06-04 2014-07-30 中国人民解放军军事医学科学院毒物药物研究所 4-羟基喹啉-3-酰胺衍生物及其制备方法和用途
AU2011314411B2 (en) 2010-10-14 2014-06-12 Immunahr Ab 1,2-dihydro-4-hydroxy-2-oxo-quinoline-3-carboxanilides as AhR activators.
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
EP2537517A1 (en) * 2011-06-22 2012-12-26 Active Biotech AB Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide
EA201490748A1 (ru) 2011-10-12 2014-12-30 Тева Фармасьютикал Индастриз Лтд. Лечение рассеянного склероза комбинацией лахинимода и финголимода
BR112014018485A8 (pt) 2012-02-03 2017-07-11 Teva Pharma Uso de laquinimod para tratar pacientes com a doença de crohn que falharam com a primeira linha de terapia anti-tnf
US20130224293A1 (en) 2012-02-27 2013-08-29 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
TW201400117A (zh) 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
KR20150091077A (ko) 2012-11-07 2015-08-07 테바 파마슈티컬 인더스트리즈 리미티드 라퀴니모드의 아민염
SG11201505952WA (en) * 2013-01-31 2015-08-28 Vertex Pharma Quinoline and quinazoline amides as modulators of sodium channels
US9233927B2 (en) 2013-03-14 2016-01-12 Teva Pharmaceutical Industries, Ltd. Crystals of laquinimod sodium and improved process for the manufacture thereof
MX2016013944A (es) 2014-04-29 2017-01-09 Teva Pharma Laquinimod para el tratamiento de pacientes con esclerosis multiple recidivante-remitente (rrms) con un alto estado de discapacidad.
RU2749213C2 (ru) 2014-10-07 2021-06-07 Вертекс Фармасьютикалз Инкорпорейтед Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE635597A (US06272168-20010807-M00014.png) * 1962-03-01
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
FR2281761A1 (fr) * 1974-08-13 1976-03-12 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
JPS623152B2 (US06272168-20010807-M00014.png) 1987-01-23
NL7701398A (nl) 1977-08-15
US4107310A (en) 1978-08-15
CH620437A5 (US06272168-20010807-M00014.png) 1980-11-28
SE441528B (sv) 1985-10-14
AU508345B2 (en) 1980-03-20
FR2340735B1 (US06272168-20010807-M00014.png) 1978-11-03
DK150512C (da) 1987-11-16
SU867299A3 (ru) 1981-09-23
BE851306A (fr) 1977-08-10
FR2340735A1 (fr) 1977-09-09
ES455804A1 (es) 1978-01-16
IL51413A (en) 1980-09-16
DK56077A (da) 1977-08-12
AU2221877A (en) 1978-08-17
IL51413A0 (en) 1977-04-29
LU76742A1 (US06272168-20010807-M00014.png) 1977-08-19
GB1572482A (en) 1980-07-30
CA1089464A (fr) 1980-11-11
SE7700804L (sv) 1977-08-12
DE2705446A1 (de) 1977-08-18
JPS52116479A (en) 1977-09-29
IE44879L (en) 1977-08-11
DE2705446C2 (US06272168-20010807-M00014.png) 1989-10-12
ZA77787B (en) 1978-03-29
DK150512B (da) 1987-03-16
IE44879B1 (en) 1982-05-05

Similar Documents

Publication Publication Date Title
DD129552A5 (de) Verfahren zur herstellung von derivaten der 3-chinolinkarbonsaeure
DD134526A5 (de) Verfahren zur herstellung von alkyloxinderivaten der 7-aminothiazolylazetamidozephalosporansaeure
DD133952A5 (de) Verfahren zur herstellung von n-phosphonomethylglycinsalzen
DD128812A5 (de) Verfahren zur herstellung von chinazolonderivaten
DD129781A5 (de) Verfahren zur herstellung von glucoseaminderivaten
AT351187B (de) Verfahren zur herstellung von 7-dehydrochol- esterinderivaten
AT358572B (de) Verfahren zur herstellung von 5-aroyl-1- niederalkyl-pyrrol-2-essigsaeure-derivaten
ATA292078A (de) Verfahren zur herstellung von neuen 9-amino- desoxyclavulansaeurederivaten
DD130576A5 (de) Verfahren zur herstellung von derivaten von 5-hydroxy-chininzarinchinon
DD128196A5 (de) Verfahren zur herstellung von clavulansaeure-thioaethern
DD132429A5 (de) Verfahren zur herstellung von derivaten von phenoxyalkansaeuren
AT351019B (de) Verfahren zur herstellung von 2-(p-amylbenzoyl) -benzoesaeure
DD138652A5 (de) Verfahren zur herstellung von 2-hydrazono-propionsaeure-derivaten
DD129791A5 (de) Verfahren zur herstellung von naphtyridinderivaten
ATA706577A (de) Verfahren zur herstellung von substituierten 1-carbamoyl-2-cyanaziridinen
ATA425476A (de) Verfahren zur herstellung von steroid-carbon- saeurelactonen
DD129785A5 (de) Verfahren zur herstellung von indazolderivaten
DD135388A5 (de) Verfahren zur herstellung von oxazolinoazetidinylpentencarbonsaeure-derivaten
DD136136A5 (de) Verfahren zur herstellung von pyridincarbonsaeureamiden
AT345268B (de) Verfahren zur herstellung von sulfamylbenzoesaeuren
DD135485A5 (de) Verfahren zur herstellung von nitroalkanolderivaten
AT352144B (de) Verfahren zur herstellung von o,o-dialkyl-s-(n- methyl-carboxamidomethyl) -thiolphosphorsaeureestern
AT347434B (de) Verfahren zur herstellung der 2-(3- benzyolphenyl)-propionsaeure
AT347929B (de) Verfahren zur herstellung von triphenylalken- derivaten
AT341674B (de) Verfahren zur herstellung von 7- (d-2-amino-3-phenylacetamido)-3-methyl-3-cephem-4-carbonsaure

Legal Events

Date Code Title Description
PJ Ceased due to non-payment of renewal fee (addendum to changes before extension act)