CZ298845B6 - Apparatus for filtering blood plasma - Google Patents

Abstract

The present invention relates to an apparatus for filtering blood plasma comprising a filter element (3) being connected with a blood plasma supply tube (1) and a blood plasma discharge tube (4), a regeneration liquid supply tube (7) and a liquid discharge tube (10). Said liquid discharge tube (10) being connected to a discharge trap (11) is provided with a branch (12) having a discharge neck (13) and a closing element (14). When cleaning the filter element (3) the blood plasma, optionally the regeneration liquid flows off through the liquid discharge tube (10) to the discharge trap (11). Blood plasma or regeneration liquid take-off is carried out by a syringe put on the branch (12) discharge neck (13).

Description

Device for blood plasma filtration

Technical field

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a blood plasma filtering device comprising a filter element to which blood plasma inlet and outlet tubes, regenerative fluid supply tubes and fluid removal tubes are connected.

BACKGROUND OF THE INVENTION

Blood plasma filtration devices are disclosed, as disclosed in WO 87/06471, comprising a controller for adding a fluid to the blood disposed between a pump and a separator formed by a centrifuge for separating the blood into various components. Blood is mixed with the added fluid and drained back into the patient's body. WO 98/50091 discloses a control unit for a blood filtering member, where the filtration is performed in two sections through a semipermeable membrane and the blood flow is conveyed in one section by a pump and in the other section blood is ultrafiltrated in connection with a dosing line connected to a container with means for weighing the ultrafiltrate. Each section is equipped with mixers and the whole process is controlled by an electronic controller. Plasma filtration is also addressed in JP2177962, comprising two sections, one with a filter and the other with a centrifugal separator. EP 650737, in turn, includes a plasma filtration device performing separation of platelets from plasma in primary filtration and plasma purification in secondary filtration, the principle of which is based on filtration pressure ratios. These solutions are new solutions for plasma filtration and separation circuits, including the use of electronic systems, but as these structures imply, a recovery liquid or plasma discharge tube must be connected to a collection bag and sampling can only be performed after removal of the bag a prior art blood plasma filtering device comprising a filter element to which the blood plasma inlet and outlet tubes, the recovery fluid supply tube and the fluid removal tube are connected. The collection of these fluids, i.e., the regenerative liquid or plasma, into the collection bags requires constant collection of the collection bags, which is inefficient and also imposes a certain burden on the operator. Sampling may only be performed after removal of the collection bag.

It is therefore an object of the present invention to provide a blood plasma filtering device which avoids the need to use collection bags and thus allows more economical and less demanding operation of the blood plasma filtering device.

SUMMARY OF THE INVENTION

This object is achieved by a device according to the invention, characterized in that the fluid removal tube is connected to a drain well and is provided with a branch with a removal throat and a closing element. When filling or regenerating the filter element, the regeneration liquid or blood plasma is discharged through a tube for draining fluids to the drain well and the supply of this liquid to the tap-off branch is closed. Conversely, when collecting a sample filtered from blood plasma or regenerative fluid, the closure element is opened, the sterile cap is removed, a syringe is inserted into the sampling throat and a sample is taken in a sterile manner from which the required examinations or measurements can be performed.

Overview of the drawings

The blood plasma filtering device according to the invention is shown schematically in the attached drawing.

-1 CZ 298845 B6

DETAILED DESCRIPTION OF THE INVENTION

The device consists of a blood supply tube 1, in which a blood plasma supply solenoid valve 2 is inserted and the blood supply tube 1 is introduced into a filter element 3 from which a blood plasma discharge tube 4 is provided, provided with a blood plasma solenoid valve 5, wherein before the blood plasma solenoid valve 2 and the blood plasma solenoid valve 5, the blood plasma delivery tube 1 is connected to the blood plasma discharge tube 4 by a bypass tube 6. Before being connected to the filter element 3, the blood plasma delivery tube 1 is connected to the blood delivery tube 7. a regeneration liquid in which the pump 8 is located, wherein the regeneration liquid supply tube 7 is discharged from the regeneration liquid storage bag 9. From the filter element 3, a fluid removal tube 10 is also introduced, which is introduced into the drain well 11 and is provided with a branch 12 with a removal throat.

13, adapted to receive a syringe and provided with a closure element 14. The fluid removal tube 10 is also provided with a fluid removal solenoid valve 15. The fluid removal tube 10 is also provided with a fluid removal solenoid valve.

Blood plasma is fed through the plasma delivery tube 1 via the open plasma delivery solenoid valve 2 to the filter element 3 where it is filtered. It is then discharged by the blood plasma discharge tube 4 through the open blood plasma solenoid valve 5. After the limit contamination of the filter element 3 is exceeded, the blood plasma solenoid valve 2 and the blood plasma solenoid valve 5 are closed, the closure 16 is opened, and the filter element 3 is supplied with the regenerative liquid feed tube 7 pumped by the pump 8 from the regenerative storage bag 9. The fluid removal solenoid valve 15 is opened. The recovery liquid to be discharged flows through the fluid discharge tube 10 into the drain well 11. The closure element 14 is closed. The blood plasma filtration process does not take place at this point in time, and the supplied blood plasma is transferred through a bypass tube 6 to a blood plasma discharge tube 4. To check the cleansing of the filter element 3 or to take a blood plasma sample for various examinations, it is possible to place the syringe on the withdrawal neck 13 of the branch 12 and open the closure element 14. The collection can be performed sterile. After removal, the closure element 14 is closed again and the syringe is removed from the take-off throat 13 of the branch 12 and the cap is fitted. After the performance has been effected, the supply of regeneration liquid to the filter element 3 is stopped by switching off the pump 8, the closure 16 is closed on the regeneration liquid supply tube 7 and the liquid removal solenoid valve 15 is closed on the liquid discharge tube 10. The blood plasma solenoid valve 2 and the blood plasma solenoid valve 5 are opened again and the blood plasma filtration continues.

Claims (1)

PATENT CLAIMS A blood plasma filtering device comprising a filter element to which a plasma water and drain tube, a regeneration fluid supply tube, and a liquid drain tube are connected, wherein the liquid drain tube (10) is connected to a drain well. (11) and is provided with a branch (12) with a removal throat (13) and a closing element (14).