CY2026A - Use of 4H-1-benzopyran-4-one derivatives 4H-1-benzopyran-4-one derivatives and medicines containing same - Google Patents

Use of 4H-1-benzopyran-4-one derivatives 4H-1-benzopyran-4-one derivatives and medicines containing same

Info

Publication number
CY2026A
CY2026A CY202698A CY202698A CY2026A CY 2026 A CY2026 A CY 2026A CY 202698 A CY202698 A CY 202698A CY 202698 A CY202698 A CY 202698A CY 2026 A CY2026 A CY 2026A
Authority
CY
Cyprus
Prior art keywords
benzopyran
derivatives
containing same
medicines containing
compounds
Prior art date
Application number
CY202698A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CY2026A publication Critical patent/CY2026A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
CY202698A 1988-10-28 1998-02-20 Use of 4H-1-benzopyran-4-one derivatives 4H-1-benzopyran-4-one derivatives and medicines containing same CY2026A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3836676A DE3836676A1 (de) 1988-10-28 1988-10-28 Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
CY2026A true CY2026A (en) 1998-02-20

Family

ID=6366059

Family Applications (1)

Application Number Title Priority Date Filing Date
CY202698A CY2026A (en) 1988-10-28 1998-02-20 Use of 4H-1-benzopyran-4-one derivatives 4H-1-benzopyran-4-one derivatives and medicines containing same

Country Status (14)

Country Link
EP (1) EP0366061B1 (da)
JP (1) JP2879910B2 (da)
KR (1) KR100194505B1 (da)
AT (1) ATE133170T1 (da)
AU (1) AU628409B2 (da)
CA (1) CA1336715C (da)
CY (1) CY2026A (da)
DE (2) DE3836676A1 (da)
DK (1) DK175228B1 (da)
ES (1) ES2084593T3 (da)
GR (1) GR3018739T3 (da)
HK (1) HK1006167A1 (da)
IE (1) IE69982B1 (da)
PT (1) PT92145B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284856A (en) * 1988-10-28 1994-02-08 Hoechst Aktiengesellschaft Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
EP0508347A1 (en) * 1991-04-10 1992-10-14 Hoechst Aktiengesellschaft 5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl)) piperidinyl]-4H-1-benzopyran-4-one, its preparation and its use
US5464871A (en) * 1993-05-12 1995-11-07 Octamer, Inc. Aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents
US5733920A (en) * 1995-10-31 1998-03-31 Mitotix, Inc. Inhibitors of cyclin dependent kinases
DE59712561D1 (de) * 1996-03-12 2006-04-13 Sanofi Aventis Deutschland Neuartige Prodrugs für die Therapie von Tumoren und entzündlichen Erkrankungen
DE19802449A1 (de) 1998-01-23 1999-07-29 Hoechst Marion Roussel De Gmbh Verfahren zur Herstellung von (-)cis-3-Hydroxy-1-methyl-4-(2,4,6-trimethoxypyhenyl)-piperidin
DE19959546A1 (de) * 1999-12-09 2001-06-21 Rhone Poulenc Rorer Gmbh Pharmazeutische Zubereitung zur Behandlung von Tumorerkrankungen
US6821990B2 (en) 2000-01-18 2004-11-23 Aventis Pharma Deutschland Gmbh Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5, 7-dihydroxy-8 [4R-(3S-hydroxy-1-M ethyl) piperidinyl]-4H-1-benzopyran-4-one
US6576647B2 (en) 2000-01-18 2003-06-10 Aventis Pharmaceuticals Inc. Pseudopolymorph of (—)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4R-(3S-hydroxy -1-methyl)piperidinyl]-4H-1-benzopyran-4-one
ES2228800T3 (es) * 2000-01-18 2005-04-16 Aventis Pharmaceuticals Inc. Solvato de etanol de (-)-cis-2-(2-clorofenil)-5,7-dihidroxi-8-(4r-(3s-hidroxi-1-metil)piperidinil)-4h-1-benzopiran-4-ona.
FR2805538B1 (fr) * 2000-02-29 2006-08-04 Hoechst Marion Roussel Inc Nouveaux derives de flavones, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
KR100392468B1 (ko) * 2000-09-18 2003-07-22 주식회사 엘지생명과학 사이클린 의존 키나아제의 저해제로서 유용한3-히드록시크로멘-4-온 유도체
DE10113513A1 (de) * 2001-03-20 2002-10-02 Medinnova Ges Med Innovationen Kombinationspräparat zur Prophylaxe und/oder Therapie von Nervenzell- und/oder Gliazellschäden durch ein neues Behandlungsverfahren
US7547716B2 (en) 2001-06-08 2009-06-16 Institute Of Medicinal Molecular Design, Inc. Sulfonamide derivatives
JP4664597B2 (ja) 2002-04-17 2011-04-06 サイトキネティクス・インコーポレーテッド 化合物、組成物および方法
TWI331034B (en) * 2002-07-08 2010-10-01 Piramal Life Sciences Ltd Inhibitors of cyclin-dependent kinases and their use
WO2004006865A2 (en) 2002-07-17 2004-01-22 Cytokinetics, Inc. Compounds, compositions, and methods
US20120121692A1 (en) * 2009-05-08 2012-05-17 Shandong University Compounds and compositions comprising cdk inhibitors and methods for treating cancer
EP2580320B1 (en) 2010-06-14 2018-08-01 The Scripps Research Institute Reprogramming of cells to a new fate
WO2012007327A1 (en) 2010-07-12 2012-01-19 Dkfz Deutsches Krebsforschungszentrum Wogonin for the prevention and therapy of cardiac hypertrophy
WO2013113762A1 (en) 2012-01-31 2013-08-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for predicting the risk of having a cutaneous melanoma in a subject
BR112017022666A8 (pt) 2015-04-20 2022-10-18 Tolero Pharmaceuticals Inc Preparando resposta à alvocidib por perfilamento mitocondrial
TR201911032T4 (tr) 2015-05-18 2019-08-21 Tolero Pharmaceuticals Inc Artırılmış biyoyararlanıma sahip alvocıdıb ön ilaçları.
AU2016301315C1 (en) 2015-08-03 2022-07-07 Sumitomo Pharma Oncology, Inc. Combination therapies for treatment of cancer
WO2018094275A1 (en) 2016-11-18 2018-05-24 Tolero Pharmaceuticals, Inc. Alvocidib prodrugs and their use as protein kinase inhibitors
US11497756B2 (en) 2017-09-12 2022-11-15 Sumitomo Pharma Oncology, Inc. Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
CA3119807A1 (en) 2018-12-04 2020-06-11 Sumitomo Dainippon Pharma Oncology, Inc. Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
WO2020191326A1 (en) 2019-03-20 2020-09-24 Sumitomo Dainippon Pharma Oncology, Inc. Treatment of acute myeloid leukemia (aml) with venetoclax failure
CN110028475B (zh) * 2019-05-13 2022-07-01 中国药科大学 基于苯并吡喃结构的新型cdk9抑制剂、其制备方法及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329186A1 (de) * 1983-08-12 1985-02-21 Hoechst Ag, 6230 Frankfurt Chromonalkaloid, verfahren zu seiner isolierung aus dysoxylum binectariferum, und seine verwendung als arzneimittel
IN164232B (da) * 1986-04-11 1989-02-04 Hoechst India

Also Published As

Publication number Publication date
ES2084593T3 (es) 1996-05-16
IE69982B1 (en) 1996-10-16
DK537289D0 (da) 1989-10-27
DE3836676A1 (de) 1990-05-03
AU4384189A (en) 1990-05-03
PT92145A (pt) 1990-04-30
KR900006325A (ko) 1990-05-07
HK1006167A1 (en) 1999-02-12
PT92145B (pt) 1995-06-30
ATE133170T1 (de) 1996-02-15
JP2879910B2 (ja) 1999-04-05
DK175228B1 (da) 2004-07-19
IE893481L (en) 1990-04-28
AU628409B2 (en) 1992-09-17
DK537289A (da) 1990-04-29
KR100194505B1 (ko) 1999-06-15
GR3018739T3 (en) 1996-04-30
CA1336715C (en) 1995-08-15
EP0366061B1 (de) 1996-01-17
DE58909573D1 (de) 1996-02-29
JPH02178225A (ja) 1990-07-11
EP0366061A1 (de) 1990-05-02

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