CY1124713T1 - Μεθοδοι χορηγησης υψηλων συγκεντρωσεων νιτρικου οξειδιου - Google Patents

Μεθοδοι χορηγησης υψηλων συγκεντρωσεων νιτρικου οξειδιου

Info

Publication number
CY1124713T1
CY1124713T1 CY20211100967T CY211100967T CY1124713T1 CY 1124713 T1 CY1124713 T1 CY 1124713T1 CY 20211100967 T CY20211100967 T CY 20211100967T CY 211100967 T CY211100967 T CY 211100967T CY 1124713 T1 CY1124713 T1 CY 1124713T1
Authority
CY
Cyprus
Prior art keywords
nitric oxide
methods
high concentrations
administering
administering high
Prior art date
Application number
CY20211100967T
Other languages
English (en)
Inventor
Brahm Goldstein
Douglas Stuart GREENE
Original Assignee
Mallinckrodt Hospital Products IP Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2013/031665 external-priority patent/WO2013138654A1/en
Application filed by Mallinckrodt Hospital Products IP Limited filed Critical Mallinckrodt Hospital Products IP Limited
Publication of CY1124713T1 publication Critical patent/CY1124713T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Περιγράφονται μέθοδοι χορήγησης θεραπευτικών αερίων που περιλαμβάνουν υψηλές συγκεντρώσεις νιτρικού οξειδίου, ιδιαιτέρως συγκεντρώσεις πάνω από 2000 ppm. To θεραπευτικό αέριο μπορεί να χορηγείται σε ορισμένο ρυθμό δοσολογίας, όπως για παράδειγμα λιγότερο από 166 μικρογραμμάρια του οξειδίου του αζώτου ανά δευτερόλεπτο. Επίσης περιγράφονται μέθοδοι χορήγησης θεραπευτικού αερίου που περιλαμβάνει νιτρικό οξείδιο σε έναν ασθενή, όπου μία δόση νιτρικού οξειδίου χορηγείται από μία φορητή συσκευή που περιλαμβάνει σύστημα απελευθέρωσης και μινι-κύλινδρο. Επίσης περιγράφονται μέθοδοι διακεκομμένης χορήγησης παλμών νιτρικού οξειδίου.
CY20211100967T 2012-03-15 2021-11-09 Μεθοδοι χορηγησης υψηλων συγκεντρωσεων νιτρικου οξειδιου CY1124713T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/420,852 US20130239962A1 (en) 2012-03-15 2012-03-15 Methods Of Administering High Concentrations Of Nitric Oxide
PCT/US2013/031665 WO2013138654A1 (en) 2012-03-15 2013-03-14 Methods of administering high concentrations of nitric oxide

Publications (1)

Publication Number Publication Date
CY1124713T1 true CY1124713T1 (el) 2022-07-22

Family

ID=49156514

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20211100967T CY1124713T1 (el) 2012-03-15 2021-11-09 Μεθοδοι χορηγησης υψηλων συγκεντρωσεων νιτρικου οξειδιου

Country Status (9)

Country Link
US (1) US20130239962A1 (el)
EP (2) EP2825179B1 (el)
CN (1) CN109908169A (el)
CY (1) CY1124713T1 (el)
DK (1) DK2825179T3 (el)
ES (1) ES2894962T3 (el)
HK (1) HK1206255A1 (el)
PL (1) PL2825179T3 (el)
PT (1) PT2825179T (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2991025B1 (fr) * 2012-05-24 2014-07-04 Air Liquide Sante Int Conditionnement d'un melange gazeux no/azote a haute concentration en no
KR20180095504A (ko) * 2015-10-01 2018-08-27 말린크로트 하스피탈 프로덕츠 아이피 리미티드 흡입 치료 가스로 고농도 no를 확산시키는 장치 및 방법
CN107875489A (zh) * 2017-12-12 2018-04-06 中山市陶净科技有限公司 可控气量的呼吸装置
BR112020013109A2 (pt) * 2017-12-28 2020-11-24 Bellerophon Pulse Technologies Llc administração pulsada de óxido nítrico inalado para o tratamento da hipertensão pulmonar
EP3793437A4 (en) * 2018-05-17 2022-02-23 Bellerophon Therapeutics METHOD AND DEVICE FOR PULSATING NITROUS OXIDE DELIVERMENT
EP4017563A4 (en) * 2019-08-23 2024-04-03 Nota Laboratories, LLC NITRIC OXIDE GENERATION SYSTEMS
AU2020393170A1 (en) 2019-11-25 2022-07-14 Beyond Air, Inc. System and method for delivery of gas to a tissue

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5417950A (en) * 1994-07-07 1995-05-23 The Boc Group, Inc. Process for the purification of nitric oxide
US5823180A (en) * 1995-04-03 1998-10-20 The General Hospital Corporation Methods for treating pulmonary vasoconstriction and asthma
DK0973443T3 (da) * 1997-01-17 2006-07-24 Ino Therapeutics Gmbh Styret gasforsyningssystem
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
WO2006084911A2 (en) * 2005-02-11 2006-08-17 Nolabs Ab Improved device for application of medicaments, manufacturing method therefor, and method of treatment
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US20110245759A1 (en) * 2008-07-30 2011-10-06 Nitric Biotherapeutics, Inc. Methods of Treating An Infection with Nitric Oxide

Also Published As

Publication number Publication date
EP2825179A1 (en) 2015-01-21
EP3970729A3 (en) 2022-03-30
EP3970729A2 (en) 2022-03-23
DK2825179T3 (da) 2021-11-15
EP2825179B1 (en) 2021-08-11
US20130239962A1 (en) 2013-09-19
ES2894962T3 (es) 2022-02-16
PL2825179T3 (pl) 2022-01-10
CN109908169A (zh) 2019-06-21
HK1206255A1 (en) 2016-01-08
PT2825179T (pt) 2021-10-29

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