CY1123646T1 - Μεθοδος παρασκευης ωτικων προγονικων κυτταρων - Google Patents

Μεθοδος παρασκευης ωτικων προγονικων κυτταρων

Info

Publication number
CY1123646T1
CY1123646T1 CY20201101137T CY201101137T CY1123646T1 CY 1123646 T1 CY1123646 T1 CY 1123646T1 CY 20201101137 T CY20201101137 T CY 20201101137T CY 201101137 T CY201101137 T CY 201101137T CY 1123646 T1 CY1123646 T1 CY 1123646T1
Authority
CY
Cyprus
Prior art keywords
progenitor cells
ear progenitor
preparing
relates
preparing ear
Prior art date
Application number
CY20201101137T
Other languages
English (en)
Inventor
Carlos Marcelo Nicolas Rivolta
Darrell Michael BARROTT
Original Assignee
The University Of Sheffield
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Sheffield filed Critical The University Of Sheffield
Publication of CY1123646T1 publication Critical patent/CY1123646T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε μια βελτιωμένη μέθοδο για παραγωγή ωτικών προγονικών κυττάρων. Η εφεύρεση αναφέρεται επίσης σε χρήσεις των εν λόγω ωτικών προγονικών κυττάρων, για παράδειγμα ως φαρμάκων (π.χ. στη θεραπεία απώλειας ακοής, κώφωσης ή άλλης ακουστικής διαταραχής που σχετίζεται με απώλεια λειτουργίας του εσωτερικού αυτιού) και/ή σε μεθόδους διαλογής φαρμάκων.
CY20201101137T 2015-03-31 2020-11-30 Μεθοδος παρασκευης ωτικων προγονικων κυτταρων CY1123646T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1505605.4A GB201505605D0 (en) 2015-03-31 2015-03-31 Method for producing otic progenitors
PCT/GB2016/050882 WO2016156831A1 (en) 2015-03-31 2016-03-30 Method for producing otic progenitors

Publications (1)

Publication Number Publication Date
CY1123646T1 true CY1123646T1 (el) 2022-03-24

Family

ID=53178493

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20201101137T CY1123646T1 (el) 2015-03-31 2020-11-30 Μεθοδος παρασκευης ωτικων προγονικων κυτταρων

Country Status (13)

Country Link
US (2) US10844351B2 (el)
EP (1) EP3277801B1 (el)
CY (1) CY1123646T1 (el)
DK (1) DK3277801T3 (el)
ES (1) ES2834773T3 (el)
GB (1) GB201505605D0 (el)
HR (1) HRP20201917T1 (el)
HU (1) HUE053428T2 (el)
LT (1) LT3277801T (el)
PT (1) PT3277801T (el)
RS (1) RS61252B1 (el)
SI (1) SI3277801T1 (el)
WO (1) WO2016156831A1 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107073042A (zh) 2014-09-03 2017-08-18 布里格海姆妇女医院公司 用于产生内耳毛细胞来治疗听力损失的组合物、系统和方法
US11911416B2 (en) 2018-08-01 2024-02-27 University Of Iowa Research Foundation Compositions and methods to restore hearing loss and balance through embryonic ear transplant
EP3837351A1 (en) 2018-08-17 2021-06-23 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by downregulating foxo
WO2023167986A1 (en) * 2022-03-02 2023-09-07 Lineage Cell Therapeutics, Inc. Methods and compositions for treating hearing loss
GB202213060D0 (en) 2022-09-07 2022-10-19 Rinri Therapeutics Ltd Surgical method for treatment of auditory disease or condition
GB202214291D0 (en) 2022-09-29 2022-11-16 Rinri Therapeutics Ltd Laminin culture protocol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2667881A4 (en) 2011-01-24 2015-04-22 Univ Leland Stanford Junior METHODS OF GENERATING IN VITRO INTERNAL EAR CELLS
MX340004B (es) * 2011-01-26 2016-06-22 Curtain Wall Design And Consulting Inc Montajes para una estructura.
US9624468B2 (en) * 2012-05-04 2017-04-18 Indiana University Research & Technology Corporation Methods for generating the inner ear and other cranial placode-derived tissues using pluripotent stem cells

Also Published As

Publication number Publication date
HRP20201917T1 (hr) 2021-04-16
US20180087026A1 (en) 2018-03-29
EP3277801A1 (en) 2018-02-07
RS61252B1 (sr) 2021-01-29
PT3277801T (pt) 2020-11-30
ES2834773T3 (es) 2021-06-18
US10844351B2 (en) 2020-11-24
SI3277801T1 (sl) 2021-02-26
US20210108173A1 (en) 2021-04-15
DK3277801T3 (da) 2020-12-07
WO2016156831A1 (en) 2016-10-06
LT3277801T (lt) 2021-01-11
HUE053428T2 (hu) 2021-07-28
GB201505605D0 (en) 2015-05-13
EP3277801B1 (en) 2020-10-07

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