CY1123272T1 - Προϊοντα και μεθοδοι για θεραπεια αμυοτροφικης πλευρικης σκληρυνσης - Google Patents

Προϊοντα και μεθοδοι για θεραπεια αμυοτροφικης πλευρικης σκληρυνσης

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Publication number
CY1123272T1
CY1123272T1 CY20201100717T CY201100717T CY1123272T1 CY 1123272 T1 CY1123272 T1 CY 1123272T1 CY 20201100717 T CY20201100717 T CY 20201100717T CY 201100717 T CY201100717 T CY 201100717T CY 1123272 T1 CY1123272 T1 CY 1123272T1
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Cyprus
Prior art keywords
methods
treatment
lateral sclerosis
amyotrophic lateral
products
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CY20201100717T
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English (en)
Inventor
Brian K. Kaspar
Kevin Foust
Don W. Cleveland
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Research Institute At Nationwide Children's Hospital
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Application filed by Research Institute At Nationwide Children's Hospital filed Critical Research Institute At Nationwide Children's Hospital
Publication of CY1123272T1 publication Critical patent/CY1123272T1/el

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    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
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    • C12Y115/01001—Superoxide dismutase (1.15.1.1)
    • A—HUMAN NECESSITIES
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract

Η παρούσα εφεύρεση αφορά σε RNA-βασιζόμενες μεθόδους για αναστολή της έκφρασης του γονιδίου δισμουτάσης υπεροξειδίου 1 (SOD-1). Ανασυνδυασμένοι αδενο-συναφείς ιοί της εφεύρεσης απελευθερώνουν DNAs που κωδικοποιούν RNAs που εξουδετερώνουν την έκφραση του SOD-1. Οι μέθοδοι έχουν εφαρμογή στη θεραπεία αμυοτροφικής πλευρικής σκλήρυνσης.
CY20201100717T 2013-08-27 2020-08-04 Προϊοντα και μεθοδοι για θεραπεια αμυοτροφικης πλευρικης σκληρυνσης CY1123272T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361870585P 2013-08-27 2013-08-27
PCT/US2014/052753 WO2015031392A1 (en) 2013-08-27 2014-08-26 Products and methods for treatment of amyotrophic lateral sclerosis

Publications (1)

Publication Number Publication Date
CY1123272T1 true CY1123272T1 (el) 2021-12-31

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Country Status (15)

Country Link
US (4) US20160272976A1 (el)
EP (3) EP3702466B1 (el)
CA (1) CA2922500A1 (el)
CY (1) CY1123272T1 (el)
DK (2) DK3039146T3 (el)
ES (2) ES2799437T3 (el)
FI (1) FI3702466T3 (el)
HR (2) HRP20230015T1 (el)
HU (2) HUE050546T2 (el)
LT (2) LT3702466T (el)
PL (1) PL3702466T3 (el)
PT (2) PT3039146T (el)
RS (2) RS63942B1 (el)
SI (2) SI3702466T1 (el)
WO (1) WO2015031392A1 (el)

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EP4219727A3 (en) 2023-09-06
PT3039146T (pt) 2020-08-11
DK3702466T5 (da) 2024-08-26
EP3702466A1 (en) 2020-09-02
PT3702466T (pt) 2023-01-24
SI3702466T1 (sl) 2023-04-28
ES2799437T3 (es) 2020-12-17
DK3702466T3 (da) 2023-03-20
PL3702466T3 (pl) 2023-04-24
EP3702466B1 (en) 2022-12-28
EP3039146B1 (en) 2020-05-27
WO2015031392A9 (en) 2015-06-18
SI3039146T1 (sl) 2020-10-30
US20190144868A1 (en) 2019-05-16
LT3039146T (lt) 2020-07-27
CA2922500A1 (en) 2015-03-05
EP4219727A2 (en) 2023-08-02
US20240344071A1 (en) 2024-10-17
HRP20200862T1 (hr) 2020-08-21
EP3039146A1 (en) 2016-07-06
HUE061629T2 (hu) 2023-07-28
US20210108209A1 (en) 2021-04-15
RS60434B1 (sr) 2020-07-31
US10793861B2 (en) 2020-10-06
FI3702466T3 (fi) 2023-03-23
HUE050546T2 (hu) 2020-12-28
US20160272976A1 (en) 2016-09-22
LT3702466T (lt) 2023-02-27
DK3039146T3 (da) 2020-08-10
HRP20230015T1 (hr) 2023-02-17
RS63942B1 (sr) 2023-02-28
ES2936220T3 (es) 2023-03-15
WO2015031392A1 (en) 2015-03-05

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